期刊
JOURNAL OF THE MECHANICAL BEHAVIOR OF BIOMEDICAL MATERIALS
卷 4, 期 6, 页码 909-920出版社
ELSEVIER SCIENCE BV
DOI: 10.1016/j.jmbbm.2011.03.007
关键词
Biomechanics; Bone remodelling; Multiphysical phenomena; Multiscale analysis; Poromechanics; Numerical simulations
Cortical bone, constituting the outer shell of long bones, is continuously renewed by bone cells in response to daily stimuli. This process, known as bone remodelling, is essential for proper bone functioning in both physiological and pathological conditions. Classical bone remodelling models do not, or only implicitly do, take into account physico-chemical phenomena, focussing on the mechanosensitivity property of the tissue. The aim of this paper is to carry out an investigation of the multiphysical phenomena occuring in bone life. Using a recent multiscale model combining piezoelectricity and electrokinetics to poromechanics, the usual viewpoint of bone remodelling models is questioned and new research avenues are proposed. (C) 2011 Elsevier Ltd. All rights reserved.
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