Review
Biochemistry & Molecular Biology
Yu Sawada
Summary: The skin, as the outermost layer of the human body, is constantly exposed to external stimuli, which can lead to skin irritation. Occupational skin diseases, especially in the healthcare sector, are the most common work-related illnesses. During the COVID-19 pandemic, healthcare professionals experienced a range of occupational skin diseases associated with their work. This review focuses on the characteristics of these skin disorders in COVID-19-engaged healthcare professionals and explores potential pathogenesis and preventive methods.
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
(2023)
Review
Dermatology
F. Larese Filon, M. Pesce, M. S. Paulo, T. Loney, A. Modenese, S. M. John, S. Kezic, J. Macan
Summary: Healthcare workers are at increased risk of developing occupational contact dermatitis (OCD) due to frequent hand washing and glove use. Incidence rates of OCD vary among different regions and time periods, with higher rates observed in specific occupational groups like dental practitioners. Prospective cohort studies are needed to accurately estimate OCD incidence and develop prevention strategies, especially during pandemics.
JOURNAL OF THE EUROPEAN ACADEMY OF DERMATOLOGY AND VENEREOLOGY
(2021)
Article
Allergy
Andreas Brynolf, Inese Hauksson, Ola Bergendorff, Cecilia Svedman, Nils Hamnerius
Summary: During the COVID-19 pandemic, the use of face masks by healthcare workers has led to an increase in adverse skin reactions. However, no contact allergies to the tested face masks were found in this study. Eczema was the most common type of skin reaction observed.
CONTACT DERMATITIS
(2023)
Review
Dermatology
Jiade Yu, Jennifer K. Chen, Christen M. Mowad, Margo Reeder, Sara Hylwa, Sarah Chisolm, Cory A. Dunnick, Ari M. Goldminz, Sharon E. Jacob, Peggy A. Wu, Jonathan Zippin, Amber Reck Atwater
Summary: Prolonged wear of masks and respirators can lead to allergic and irritant dermatoses in healthcare workers, mainly caused by substances released from mask materials and prolonged pressure and friction. The occurrence of these skin disorders is associated with personal history and duration of wear.
JOURNAL OF THE AMERICAN ACADEMY OF DERMATOLOGY
(2021)
Article
Allergy
Aoife Hollywood, John F. Bourke
Summary: This is a case series of allergic contact dermatitis to F5 in pharmaceutical workers, confirmed by patch testing. With the globalized production of imatinib, more similar cases may arise.
CONTACT DERMATITIS
(2022)
Article
Pharmacology & Pharmacy
R. K. Barradah, M. S. Ahmad, R. A. Shaik, R. K. Ahmad, A. Badar Almutairi, W. K. Alghuyaythat
Summary: A study conducted among car garage workers in Majmaah City, Saudi Arabia found a 14.5% self-reported prevalence of eczema/contact dermatitis, with hand lesions being the most common. Workers aged 18-30, working as car mechanics, and working for more than 10 hours had a significantly higher prevalence of contact dermatitis. However, only 30% sought treatment for their condition.
EUROPEAN REVIEW FOR MEDICAL AND PHARMACOLOGICAL SCIENCES
(2021)
Article
Dermatology
Erin M. Warshaw, Lindsey M. Voller, Howard Maibach, Kathryn A. Zug, Joel G. DeKoven, Amber R. Atwater, Margo J. Reeder, Denis Sasseville, James S. Taylor, Joseph F. Fowler, Melanie D. Pratt, Jonathan Silverberg, Anthony F. Fransway, Matthew J. Zirwas, Donald Belsito, James G. Marks, Vincent A. DeLeo
Summary: A retrospective analysis of North American Contact Dermatitis Group data from 1994-2016 revealed that patients with eyelid dermatitis were more likely to be female, white, and over 40 years old, with a higher prevalence of hay fever, atopic dermatitis, or both. Allergic contact dermatitis was a common primary diagnosis among these patients.
JOURNAL OF THE AMERICAN ACADEMY OF DERMATOLOGY
(2021)
Article
Dermatology
P. B. Lima, J. A. F. Dias, D. P. Cassiano, A. C. C. Esposito, L. D. B. Miot, E. Bagatin, H. A. Miot
Summary: This study compared the efficacy and tolerability of topical 0.2% Thiamidol vs. 4% hydroquinone for facial melasma. Results showed that both treatments were equally effective in improving melasma, quality of life, and color contrast.
JOURNAL OF THE EUROPEAN ACADEMY OF DERMATOLOGY AND VENEREOLOGY
(2021)
Article
Health Care Sciences & Services
Ghadah F. Alotaibi, Hanan H. Alsalman, Rama A. Alhallaf, Rayan A. Ahmad, Hashem A. Alshareef, Jumanah Meshari Muammar, Fahad M. Alsaif, Felwah F. Alotaibi, Mohamed F. Balaha, Nehad J. Ahmed, El-Sayed Khafagy, Hadil F. Alotaibi, Rahaf Alshammari, Sarah Fatani
Summary: This study investigated the association between smoking and contact dermatitis in the Saudi population. The results suggest that the prevalence of allergic contact dermatitis may be lower in smokers compared to non-smokers, while the prevalence of irritant contact dermatitis may be higher. Further epidemiologic studies are needed to explore the role of smoking in the occurrence of contact dermatitis and its possible mechanisms.
Review
Allergy
Andrew W. Liu, Jacob E. Gillis, Tina L. Sumpter, Daniel H. Kaplan
Summary: The skin is populated by various immune cells and sensory neurons, and the interaction between the nervous and immune systems plays a crucial role in inflammatory skin diseases. Neurotransmitters secreted by nerve terminals mediate immune cell function, while immune factors derived from immune cells interact with neurons to induce itching. This review explores the effector functions of neurons on skin immune cells in mouse models of atopic and contact dermatitis, and discusses the contribution of specific neuronal subsets and immune factors to itch induction and inflammation. The findings also shed light on treatment strategies and the relationship between scratching and dermatitis.
JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY
(2023)
Article
Dermatology
Jonathan Silverberg, Erin M. Warshaw, Amber R. Atwater, Howard Maibach, Kathryn A. Zug, Margo J. Reeder, Denis Sasseville, James S. Taylor, Joseph F. Fowler, Melanie D. Pratt, Anthony F. Fransway, Matthew J. Zirwas, Donald Belsito, James G. Marks, Vincent A. DeLeo, Joel G. DeKoven
Summary: This study retrospectively analyzed data from a large number of patients with hand eczema (HE), and found that HE was associated with higher proportions of positive patch tests, with a heterogeneous profile of allergens.
JOURNAL OF THE AMERICAN ACADEMY OF DERMATOLOGY
(2021)
Article
Chemistry, Multidisciplinary
Mario Pagliaro, Anne-Sylvie Fabiano-Tixier, Rosaria Ciriminna
Summary: First reported in 2004, the use of d-limonene as a natural product extraction solvent offers various advantages beyond its eco-friendly nature. This study reviews its applications in extracting different natural products, including economic and safety considerations that are often overlooked. The study identifies three key research outcomes and provides two guidelines for bioeconomy practitioners interested in utilizing this terpene in new extraction and production processes.
Article
Allergy
Linda Piapan, Davide Bramuzzo, Francesca Rui, Francesca Larese Filon
Summary: This study investigated and compared the incidence and clinical features of occupational skin diseases (OSDs) among healthcare workers (HCWs) before and during the COVID-19 pandemic. The results showed a slight increase in the incidence of OSDs during the pandemic, with higher incidence in the winter and spring seasons. Overall, there was a non-significant increase in the incidence of OSDs in HCWs during the pandemic, likely due to the preventive strategies implemented in the cohort over the years.
CONTACT DERMATITIS
(2022)
Article
Dermatology
Holly Neale, Anna Cristina Garza-Mayers, Idy Tam, JiaDe Yu
Summary: ACD is a delayed hypersensitivity skin reaction to environmental allergens that affects children and adults similarly. However, pediatric patch testing for ACD is less common due to challenges such as smaller surface area for testing and difficulty in cooperation, particularly with younger children. Clinical suspicion guided by patient presentation and history is key in diagnosing ACD in children.
JOURNAL OF THE AMERICAN ACADEMY OF DERMATOLOGY
(2021)
Article
Dermatology
Erin M. Warshaw, Sara A. Kullberg, Joel G. DeKoven, Howard Maibach, Donald Belsito, Jonathan Silverberg, Joseph F. Fowler, Amber R. Atwater, Denis Sasseville, Margo J. Reeder, James S. Taylor, Vincent A. DeLeo, Melanie D. Pratt, Kathryn A. Zug, Anthony F. Fransway
Summary: A retrospective cross-sectional analysis of North American Contact Dermatitis Group data from 1996 to 2016 revealed that isolated scalp involvement was less likely to be associated with allergic contact dermatitis than when adjacent anatomic sites were involved. Multiple diagnoses, including seborrheic dermatitis, irritant dermatitis, and other dermatoses, overlapped frequently in patients with scalp conditions.
JOURNAL OF THE AMERICAN ACADEMY OF DERMATOLOGY
(2021)