Article
Medicine, Research & Experimental
Qiong Huang, Junhong Wang, Dianfu Li, Jihong Zhao, Xiangjun Feng, Ningtian Zhou
Summary: The study found that the combined EET+SE method has superior diagnostic efficiency in diagnosing suspected MI compared to traditional examinations, showing better sensitivity and specificity. This may reduce the prevalence of MI and medical costs.
EXPERIMENTAL AND THERAPEUTIC MEDICINE
(2021)
Article
Cardiac & Cardiovascular Systems
Serge C. Harb, Tom Kai Ming Wang, Paul C. Cremer, Yuping Wu, Leslie Cho, Venu Menon, Wael A. Jaber
Summary: Women are more likely to be referred for less demanding exercise protocols, use more imaging protocols, and achieve lower CRF levels compared to men, but after adjustment, female sex is associated with significantly lower long-term mortality for equivalent CRF levels.
INTERNATIONAL JOURNAL OF CARDIOLOGY
(2021)
Article
Cardiac & Cardiovascular Systems
Leonard Mandes, Monica Rosca, Daniela Ciuperca, Andreea Calin, Carmen C. Beladan, Roxana Enache, Andreea Cuculici, Cristian Baicus, Ruxandra Jurcut, Carmen Ginghina, Bogdan A. Popescu
Summary: This study found that atrial fibrillation (AF) is associated with electrocardiographic and echocardiographic parameters (structural and functional) in patients with hypertrophic cardiomyopathy (HCM). Specifically, left atrium booster pump function and electrical dispersion were identified as independent predictors of AF in HCM patients, providing further assessment of AF risk in patients, including those considered at lower risk based on conventional assessment of left atrial size.
FRONTIERS IN CARDIOVASCULAR MEDICINE
(2022)
Review
Acoustics
Jesus Peteiro
Summary: According to guidelines, exercise should be the first choice for stress echocardiography in patients able to exercise. Treadmill exercise with acquisition of images at peak exercise has several advantages, including high sensitivity and prognostic value. However, this method is not mentioned in the guidelines.
JOURNAL OF CLINICAL ULTRASOUND
(2022)
Article
Cardiac & Cardiovascular Systems
Hiroto Utsunomiya, Kanako Izumi, Akane Tsuchiya, Atsuo Mogami, Kosuke Takahari, Hajime Takemoto, Erasta Ramandika, Yusuke Ueda, Kiho Itakura, Yukiko Nakano
Summary: This study proposed a novel risk stratification system for severe tricuspid regurgitation and validated its prognostic significance. The findings showed that a large 3D-AROA and reduced right ventricular contractile reserve during exercise were independently associated with poor prognosis.
EUROPEAN HEART JOURNAL-CARDIOVASCULAR IMAGING
(2022)
Article
Cardiac & Cardiovascular Systems
Shinichi Goto, Divyarajsinhji Solanki, Jenine E. John, Ryuichiro Yagi, Max Homilius, Genki Ichihara, Yoshinori Katsumata, Hanna K. Gaggin, Yuji Itabashi, Calum A. MacRae, Rahul C. Deo
Summary: This study developed machine learning models using ECGs and echocardiograms to detect and differentiate hypertrophic cardiomyopathy (HCM) from other cardiac conditions. The models showed good generalizability across multiple institutions when trained in a federated manner, improving the accuracy of HCM detection.
Article
Endocrinology & Metabolism
So Young Yang, Hui-Jeong Hwang
Summary: Despite the perception of higher cardiovascular risk in patients with diabetes, this study suggests that the occurrence of cardiovascular events in patients with diabetes, who have negative results on stress echocardiography, is comparable to those without diabetes. Monitoring diastolic dysfunction, appropriate use of statins, and individualized selection of antidiabetic drugs are essential in reducing cardiovascular risk in patients with diabetes.
Article
Endocrinology & Metabolism
So Young Yang, Hui-Jeong Hwang
Summary: Despite negative stress test results, patients with diabetes have comparable cardiovascular morbidity and mortality rates to those without diabetes. Predictors of MACEs in diabetic patients include diastolic dysfunction, lack of statin and dipeptidyl peptidase-4 inhibitor use, and the use of sulfonylureas.
Article
Medicine, General & Internal
Tiantian He, Chen Liu, Weihao Liang
Summary: This study aimed to explore the prognostic value of abnormal electrocardiogram (ECG) at baseline in patients with heart failure with preserved ejection fraction (HFpEF). The results showed that abnormal ECG was significantly associated with higher risks of cardiovascular events and HF hospitalization in HFpEF patients. Specific abnormalities like bundle branch block and atrial fibrillation were also found to be predictive of adverse outcomes.
POSTGRADUATE MEDICAL JOURNAL
(2023)
Article
Medicine, General & Internal
Tsang -Wei Chang, Han -Chung Hsu, Wei-Chuan Tsai
Summary: This study examined the association between left ventricular global area strain (GAS) and exercise capacity, and found a significant association between LV GAS3d and exercise time. LV GAS3d can serve as an independent predictor of exercise capacity and improve the predictive value of early mitral filling velocity to average mitral annulus velocity for exercise capacity.
INTERNATIONAL JOURNAL OF MEDICAL SCIENCES
(2022)
Article
Cardiac & Cardiovascular Systems
Juanjuan Lu, Jie Wang, Long Yu, Rong Cui, Ying Zhang, Hanqing Ding, Guofeng Yan
Summary: The study showed that treadmill exercise improves neurobehavioral outcomes, reduces infarct volumes, and promotes the activation of M2 microglia while inhibiting M1 microglia. This effect is achieved through enhancing IL-4 expression and activating the JAK1-STAT6 pathway.
FRONTIERS IN CARDIOVASCULAR MEDICINE
(2021)
Article
Cardiac & Cardiovascular Systems
Jingru Lin, Weichun Wu, Lijian Gao, Jia He, Zhenhui Zhu, Kunjing Pang, Jiangtao Wang, Mengyi Liu, Hao Wang
Summary: The study investigates the use of global myocardial work (MW) combined with treadmill exercise stress to detect significant coronary artery disease (CAD) in patients with angina pectoris. The results show that peak global work efficiency (GWE) and recovery global wasted work (GWW) can predict significant CAD. A model combining peak GWE and recovery GWW performs better in identifying significant CAD compared to peak GWE alone. Overall, global MW parameters combined with exercise stress serve as an accurate noninvasive screening method before invasive diagnostic techniques.
JOURNAL OF THE AMERICAN SOCIETY OF ECHOCARDIOGRAPHY
(2022)
Article
Physiology
Gabriella F. Bellissimo, Jeremy Ducharme, Zachary Mang, Desmond Millender, Jessica Smith, Matthew J. Stork, Johnathan P. Little, Michael R. Deyhle, Ann L. Gibson, Flavio de Castro Magalhaes, Fabiano Amorim
Summary: This study compared the acute physiological, perceptual, and enjoyment responses between bodyweight high-intensity interval exercise (BW-HIIE) and treadmill running high-intensity interval exercise (RUN-HIIE). The results showed that BW-HIIE elicited higher oxygen consumption, blood lactate, heart rate, and rating of perceived exertion compared to RUN-HIIE, while the physical activity enjoyment was similar between the two exercises.
FRONTIERS IN PHYSIOLOGY
(2022)
Article
Cardiac & Cardiovascular Systems
Fabijan Lulic, Zdravko Virag
Summary: This study evaluated changes in Doppler mitral inflow variables from rest to post-exercise in subjects with and without echocardiographic evidence of ischemic response. The results showed that the changes in peak E-wave velocity and E-wave deceleration rate were bigger in ischemic subjects compared to nonischemic subjects. There was a significant interaction between time from exercise cessation to imaging and ischemic response.
INTERNATIONAL JOURNAL OF CARDIOVASCULAR IMAGING
(2022)
Article
Cardiac & Cardiovascular Systems
Hyungseop Kim, In-Cheol Kim, Jongmin Hwang, Hyoung-Seob Park, Cheol Hyun Lee, Yun-Kyeong Cho, Hyuck-Jun Yoon, Chang-Wook Nam, Seongwook Han, Seung-Ho Hur
Summary: This study aimed to explore the clinical implications of AS-MCE in revealing decreased coronary blood flow or perfusion defects after coronary revascularization and determine the prognostic value of PDs in asymptomatic patients following PCI. The results showed that PDs might be a complementary indicator in risk stratification along with rRWMA.
INTERNATIONAL JOURNAL OF CARDIOVASCULAR IMAGING
(2022)
Editorial Material
Cardiac & Cardiovascular Systems
Ahmed Aljizeeri, Firas Al Badarin, Mouaz H. Al-Mallah
JOURNAL OF NUCLEAR CARDIOLOGY
(2022)
Editorial Material
Cardiac & Cardiovascular Systems
Akanksha N. Thakkar, Talal S. Alnabelsi, Mouaz H. Al-Mallah
JOURNAL OF NUCLEAR CARDIOLOGY
(2022)
Article
Cardiac & Cardiovascular Systems
Alexander R. van Rosendael, A. Maxim Bax, Inge J. van den Hoogen, Jeff M. Smit, Subhi J. Al'Aref, Stephan Achenbach, Mouaz H. Al-Mallah, Daniele Andreini, Daniel S. Berman, Matthew J. Budoff, Filippo Cademartiri, Tracy Q. Callister, Hyuk-Jae Chang, Kavitha Chinnaiyan, Benjamin J. W. Chow, Ricardo C. Cury, Augustin DeLago, Gudrun Feuchtner, Martin Hadamitzky, Joerg Hausleiter, Philipp A. Kaufmann, Yong-Jin Kim, Jonathon A. Leipsic, Erica Maffei, Hugo Marques, Pedro de Araujo Goncalves, Gianluca Pontone, Gilbert L. Raff, Ronen Rubinshtein, Todd C. Villines, Heidi Gransar, Yao Lu, Jessica M. Pena, Fay Y. Lin, Leslee J. Shaw, Jagat Narula, James K. Min, Jeroen J. Bax
Summary: This study evaluated the relationship between dyspnoea, coronary artery disease (CAD), and major cardiovascular events (MACE). The findings suggest that dyspnoea is associated with severe obstructive CAD, and the severity of obstructive CAD explains the elevated MACE rates in patients with dyspnoea.
EUROPEAN HEART JOURNAL-CARDIOVASCULAR IMAGING
(2022)
Review
Cardiac & Cardiovascular Systems
Mahmoud Al Rifai, Alka M. Kanaya, Namratha R. Kandula, Jaideep Patel, Mouaz H. Al-Mallah, Matthew Budoff, Miguel Cainzos-Achirica, Michael H. Criqui, Salim S. Virani
Summary: Individuals of South Asian ancestry have a higher risk of atherosclerotic cardiovascular disease. Coronary artery calcium volume and density can identify unique plaque characteristics in this population, providing important prognostic information. Cardiovascular risk factors are associated with CAC density and volume.
CURRENT PROBLEMS IN CARDIOLOGY
(2023)
Article
Cardiac & Cardiovascular Systems
Donghee Han, Billy Chen, Heidi Gransar, Stephan Achenbach, Mouaz H. Al-Mallah, Matthew J. Budoff, Filippo Cademartiri, Erica Maffei, Tracy Q. Callister, Kavitha Chinnaiyan, Benjamin J. W. Chow, Augustin DeLago, Martin Hadamitzky, Joerg Hausleiter, Philipp A. Kaufmann, Todd C. Villines, Yong-Jin Kim, Jonathon Leipsic, Gudrun Feuchtner, Ricardo C. Cury, Gianluca Pontone, Daniele Andreini, Hugo Marques, Ronen Rubinshtein, Hyuk-Jae Chang, Fay Y. Lin, Leslee J. Shaw, James K. Min, Daniel S. Berman
Summary: This study found that proximal coronary involvement is associated with increased risk of major adverse cardiovascular events in patients with non-obstructive coronary artery disease, independent of plaque extent.
EUROPEAN HEART JOURNAL-CARDIOVASCULAR IMAGING
(2022)
Article
Cardiac & Cardiovascular Systems
Donghee Han, Andrew Lin, Keiichiro Kuronuma, Evangelos Tzolos, Alan C. Kwan, Eyal Klein, Daniele Andreini, Jeroen J. Bax, Filippo Cademartiri, Kavitha Chinnaiyan, Benjamin J. W. Chow, Edoardo Conte, Ricardo C. Cury, Gudrun Feuchtner, Martin Hadamitzky, Yong-Jin Kim, Jonathon A. Leipsic, Erica Maffei, Hugo Marques, Fabian Plank, Gianluca Pontone, Todd C. Villines, Mouaz H. Al-Mallah, Pedro de Araujo Goncalves, Ibrahim Danad, Heidi Gransar, Yao Lu, Ji-Hyun Lee, Sang-Eun Lee, Lohendran Baskaran, Subhi J. Al'Aref, Yeonyee E. Yoon, Alexander Van Rosendael, Matthew J. Budoff, Habib Samady, Peter H. Stone, Renu Virmani, Stephan Achenbach, Jagat Narula, Hyuk-Jae Chang, James K. Min, Fay Y. Lin, Leslee J. Shaw, Piotr J. Slomka, Damini Dey, Daniel S. Berman
Summary: Adverse geometric characteristics of coronary lesions are associated with the risk of future acute coronary syndrome (ACS). These geometric features provide prognostic information beyond plaque assessment.
Article
Radiology, Nuclear Medicine & Medical Imaging
Isabella Lipkin, Anha Telluri, Yumin Kim, Alfateh Sidahmed, Joseph M. Krepp, Brian G. Choi, Rebecca Jonas, Hugo Marques, Hyuk-Jae Chang, Jung Hyun Choi, Joon-Hyung Doh, Ae-Young Her, Bon-Kwon Koo, Chang-Wook Nam, Hyung-Bok Park, Sang-Hoon Shin, Jason Cole, Alessia Gimelli, Muhammad Akram Khan, Bin Lu, Yang Gao, Faisal Nabi, Ryo Nakazato, U. Joseph Schoepf, Roel S. Driessen, Michiel J. Bom, James J. Jang, Michael Ridner, Chris Rowan, Erick Avelar, Philippe Genereux, Paul Knaapen, Guus A. de Waard, Gianluca Pontone, Daniele Andreini, Mouaz H. Al-Mallah, Tami R. Crabtree, James P. Earls, Andrew D. Choi, James K. Min
Summary: This study compared the diagnostic performance of myocardial perfusion imaging (MPI) and coronary CTA with artificial intelligence quantitative CT (AI-QCT) interpretation for detecting obstructive coronary artery disease (CAD) and assessed the downstream impact of including AI-QCT in diagnostic algorithms. The results showed that AI-QCT had higher diagnostic performance than MPI, and using AI-QCT in diagnostic algorithms could substantially reduce unnecessary invasive testing and costs.
AMERICAN JOURNAL OF ROENTGENOLOGY
(2022)
Editorial Material
Cardiac & Cardiovascular Systems
Jean Michel Saad, Ahmed Ibrahim Ahmed, Mouaz H. Al-Mallah
Editorial Material
Cardiac & Cardiovascular Systems
Terrence D. Ruddy, Mouaz Al-Mallah, James A. Arrighi, John P. Bois, David A. Bluemke, Marcelo F. Di Carli, Vasken Dilsizian, Robert J. Gropler, Hossein Jadvar, Saurabh Malhotra, Matthier Pelletier-Galarneau, Thomas H. Schindler, Pamela K. Woodard, Panithaya Chareonthaitawee
CIRCULATION-CARDIOVASCULAR IMAGING
(2022)
Correction
Infectious Diseases
Michal Pazdernik, Bernard Iung, Bulent Mutlu, Francois Alla, Robert Riezebos, William Kong, Maria Carmo Pereira Nunes, Luc Pierard, Ilija Srdanovic, Hirotsugu Yamada, Andrea De Martino, Marcelo Haertel Miglioranza, Julien Magne, Cornelia Piper, Cecile Laroche, Aldo P. Maggioni, Patrizio Lancellotti, Gilbert Habib, Christine Selton-Suty
Article
Cardiac & Cardiovascular Systems
Ahmed Ibrahim Ahmed, Jean Michel Saad, Yushui Han, Maan Malahfji, Mouaz H. Al-Mallah
Summary: This study aimed to determine the prognostic value of positron emission tomography (PET) derived left ventricular mass (LVM) in addition to clinical variables and myocardial flow reserve (MFR). The results showed that LVM was not independently associated with outcomes and had no incremental prognostic value over MFR and clinical variables.
JOURNAL OF NUCLEAR CARDIOLOGY
(2023)
Editorial Material
Cardiac & Cardiovascular Systems
Maan Malahfji, Valentina Crudo, Ahmed Ibrahim Ahmed, Mujtaba Saeed, Jean Michel Saad, William A. Zoghbi, Mouaz H. Al-Mallah
JOURNAL OF NUCLEAR CARDIOLOGY
(2023)
Article
Cardiac & Cardiovascular Systems
Ahmed Ibrahim Ahmed, Mahmoud Al Rifai, Fares Alahdab, Jean Michel Saad, Yushui Han, Moath Said Alfawara, Faisal Nabi, John J. Mahmarian, Mouaz H. Al-Mallah
Summary: This study aimed to assess the prognostic value of myocardial flow reserve (MFR) using the latest generation of digital PET scanners in patients with suspected or known CAD. The results showed that impaired MFR was significantly associated with adverse events, and it significantly improved the predictive ability over traditional risk factors.
INTERNATIONAL JOURNAL OF CARDIOLOGY
(2023)
Editorial Material
Cardiac & Cardiovascular Systems
Malek Nayfeh, Ahmed Ibrahim Ahmed, Fares Alahdab, Mahmoud Al Rifai, Mouaz Al-Mallah
Editorial Material
Cardiac & Cardiovascular Systems
Abdallah El Bizri, Mouaz H. AL-Mallah