Article
Sport Sciences
Alex S. Ribeiro, Luiz C. Pereira, Brad J. Schoenfeld, Joao Pedro Nunes, Witalo Kassiano, Hellen C. G. Nabuco, Paulo Sugihara Junior, Rodrigo R. Fernandes, Melissa Antunes, Andreo F. Aguiar, Edilson S. Cyrino
Summary: This study examined the effects of protein intake on body recomposition in older women after resistance training. The results showed that protein intake is a moderating variable for body recomposition, with low protein intake having a less favorable effect.
MEDICINE & SCIENCE IN SPORTS & EXERCISE
(2022)
Article
Nutrition & Dietetics
Natalia Maira da Cruz Alves, Karina Pfrimer, Priscila Carvalho Santos, Ellen Cristini de Freitas, Thiago Neves, Rodrigo Antonio Pessini, Marcia Varella Morandi Junqueira-Franco, Marcello H. Nogueira-Barbosa, Carolyn Anne Greig, Eduardo Ferriolli
Summary: This study found that fish oil supplementation can enhance the response of sarcopenic older women to exercise, increasing muscle strength and physical performance.
Article
Medicine, General & Internal
Oscar Bergens, Andreas Nilsson, Fawzi Kadi
Summary: The study found that in older women, there was a negative association between skeletal muscle index and pro-inflammatory markers independent of lifestyle factors, while no such associations were observed in older men. This highlights the importance of considering biological sex in the interaction between systemic inflammation and muscle health.
JOURNAL OF CLINICAL MEDICINE
(2021)
Article
Geriatrics & Gerontology
Marc Sim, Jack Dalla Via, David Scott, Wai H. Lim, Jonathan M. Hodgson, Kun Zhu, Robin M. Daly, Gustavo Duque, Richard L. Prince, Joshua R. Lewis
Summary: The study found that women with low Cr:Cyc had weaker grip strength, worse performance in the timed-up-and-go test, and lower appendicular lean mass adjusted for height or body mass index. They also had a higher risk of falls and fall-related hospitalizations compared to women with high Cr:Cyc.
JOURNALS OF GERONTOLOGY SERIES A-BIOLOGICAL SCIENCES AND MEDICAL SCIENCES
(2022)
Article
Geriatrics & Gerontology
Je Hyun Seo, Young Lee
Summary: This study found that moderate to vigorous physical activity (PA) is associated with higher skeletal muscle mass and muscle strength in older adults. Specifically, engaging in high-intensity PA is positively correlated with the prevention of sarcopenia.
Article
Biology
Jort Veen, Diego Montiel-Rojas, Fawzi Kadi, Andreas Nilsson
Summary: The study investigates the impact of reallocating time spent in different intensities of physical activity (PA) on sarcopenia risk in older adults. The results show that reallocating sedentary time to at least light-intensity PA is significantly related to a lower sarcopenia risk score (SRS), even after adjustment for PA type and protein intake. Similarly, reallocating time in light- to moderate-to-vigorous-intensity PA is also related to a lower SRS. These findings emphasize the importance of displacing sedentary behaviors for more active pursuits in older adults to alleviate age-related deterioration of muscle health.
Review
Geriatrics & Gerontology
Charles Phillipe de Lucena Alves, Samuel Brito de Almeida, Danielle Pessoa Lima, Pedro Braga Neto, Ana Lucia Miranda, Todd Manini, Lara Vlietstra, Debra L. Waters, Renata Moraes Bielemann, Rosaly Correa-de-Araujo, Ana Paula Fayh, Eduardo Caldas Costa
Summary: This scoping review aimed to map out definitions and assessment methods of muscle quality in older adults. A total of 96 articles were included, revealing a substantial heterogeneity of definitions and assessment methods across functional and morphological domains. Standardizing the definition of muscle quality may help utilize it as a potential marker of skeletal muscle health in older adults.
JOURNAL OF THE AMERICAN MEDICAL DIRECTORS ASSOCIATION
(2023)
Article
Endocrinology & Metabolism
Samuel R. R. Buchanan, Ryan M. M. Miller, Michelle Nguyen, Christopher D. D. Black, J. Mikhail Kellawan, Michael G. G. Bemben, Debra A. A. Bemben
Summary: Evaluating alterations in circulating microRNA expression and its relationship with musculoskeletal health in postmenopausal women, this study found that whole-body vibration is an effective mechanical stimulus for altering c-miR-21-5p expression.
FRONTIERS IN ENDOCRINOLOGY
(2022)
Article
Biochemistry & Molecular Biology
Renata R. Bruno, Fernanda C. Rosa, Paula C. Nahas, Flavia M. S. de Branco, Erick P. de Oliveira
Summary: Aging is associated with decreased muscle strength and increased reactive oxygen species. This cross-sectional study found that serum levels of alpha-carotene were positively associated with muscle strength in older adults, while other antioxidants were not. This suggests that alpha-carotene may have a beneficial effect on muscle strength in aging individuals.
Article
Health Care Sciences & Services
Carlos A. F. Santos, Gislene R. Amirato, Alessandro F. Jacinto, Ana V. Pedrosa, Adriana Caldo-Silva, Antonio R. Sampaio, Nuno Pimenta, Juliana M. B. Santos, Alberto Pochini, Andre L. L. Bachi
Summary: This study aimed to assess the safety and usefulness of vertical jump tests in evaluating physical performance in older women. The results showed that vertical jump tests are safe and accurate, making them useful for monitoring age-related muscle performance loss in robust older women.
Review
Endocrinology & Metabolism
Yves Rolland, Cedric Dray, Bruno Vellas, Philipe De Souto Barreto
Summary: Sarcopenia, the loss of muscle mass and function, is a prevalent and severe condition in older adults. Currently, strength exercise training and nutritional support are the main treatments, as no approved drugs exist. However, few trials have specifically focused on sarcopenia patients, and most drug trials have been conducted in different older populations. While some drugs have shown effectiveness in improving muscle mass and strength, there has been limited improvement in physical performance. Promising molecules, such as apelin and irisin, are being investigated in ongoing clinical and preclinical trials.
METABOLISM-CLINICAL AND EXPERIMENTAL
(2023)
Article
Cell Biology
Levi H. Jales Neto, Bidossessi W. Hounkpe, Georgea H. Fernandes, Liliam Takayama, Neuza H. M. Lopes, Alexandre C. Pereira, Rosa M. R. Pereira
Summary: This study identified key mediators and biological mechanisms associated with age-related low muscle mass through transcriptomic analysis. The results revealed the relevance of inflammation, immunity, and metabolic alterations at the transcriptomic level, as well as significant metabolic pathways related to aging processes. The study generated a predicted regulatory network and highlighted potential key mediators for further investigation.
Article
Environmental Sciences
Mingyang Wu, Linfei Dou, Aisimila Abudoula, Yanling Shu, Youjie Wang
Summary: This study aimed to evaluate the relationship between blood and urine cadmium levels and muscle strength. The study found that there was a linear dose-response relationship between cadmium concentrations in blood and urine and muscle strength, with lower levels of cadmium associated with decreased muscle strength. This association was more evident among male participants.
ENVIRONMENTAL SCIENCE AND POLLUTION RESEARCH
(2023)
Article
Environmental Sciences
Mingyang Wu, Linfei Dou, Aisimila Abudoula, Yanling Shu, Youjie Wang
Summary: This study examined the relationship between blood and urine cadmium levels and muscle strength, finding a dose-response relationship between cadmium concentrations and decreased muscle strength, particularly in men. Further longitudinal investigations are needed to fully understand this issue.
ENVIRONMENTAL SCIENCE AND POLLUTION RESEARCH
(2023)
Article
Geriatrics & Gerontology
Simone de Azevedo Bach, Regis Radaelli, Marcio Beck Schemes, Rodrigo Neske, Charlles Garbelotto, Hamilton Roschel, Ronei Silveira Pinto, Claudia Dornelles Schneider
Summary: Supplementing whey protein to low-protein meals does not further enhance resistance training-induced muscle strength and mass adaptations in healthy older individuals.
EXPERIMENTAL GERONTOLOGY
(2022)