Article
Hematology
Heleen Alblas, Coen van Kan, Suzanne C. van Het Westeinde, Jasper Emmering, Andre Niezen, Ibrahim A. M. al Butaihi, Anton Vonk Noordegraaf, Josien van Es
Summary: This study assessed the rate of persistent dyspnea and perfusion defects after acute pulmonary embolism (PE) and their association with long-term quality of life (QoL). The results showed that persistent dyspnea was associated with a lower QoL on the long term, however no relation was found between persistent perfusion defects and a lower QoL.
THROMBOSIS RESEARCH
(2022)
Article
Geriatrics & Gerontology
Patricia M. Harasym, Misha Afzaal, Sarah Brisbin, Aynharan Sinnarajah, Lorraine Venturato, Patrick Quail, Sharon Kaasalainen, Sharon Straus, Tamara Sussman, Navjot Virk, Jayna M. Holroyd-Leduc
Summary: This two-phase study successfully identified and prioritized the top interventions needed to develop a supportive end of life care strategy for frail, older adults in long term care (LTC) homes through consensus-building approach involving multi-disciplinary stakeholders.
Article
Oncology
Alexandra S. Bercow, Roni Nitecki, Hilary Haber, Allison A. Gockley, Emily Hinchcliff, Kaitlyn James, Alexander Melamed, Elisabeth Diver, Mihir M. Kamdar, Sarah Feldman, Whitfield B. Growdon
Summary: The study investigated the impact of palliative care referral on women who died from cervical cancer in two tertiary care centers. Less than half of cervical cancer decedents received palliative care consultations, and those referred to palliative care were often evaluated late in their disease course. Palliative care utilization was associated with a lower incidence of poor-quality end-of-life care.
INTERNATIONAL JOURNAL OF GYNECOLOGICAL CANCER
(2021)
Review
Medicine, General & Internal
Emily S. Tonorezos, Richard J. Cohn, Adam W. Glaser, Jeremy Lewin, Eileen Poon, Claire E. Wakefield, Kevin C. Oeffinger
Summary: Worldwide advancements in the treatment and supportive care for children and adolescents with cancer have resulted in a growing population of survivors. However, this population is at a high risk of late occurring health problems due to knowledge gaps and fragmented healthcare during the transition from pediatric to adult care settings.
Article
Cardiac & Cardiovascular Systems
Brendan T. Heiden, Melanie P. Subramanian, Jingxia Liu, Angela Keith, Kathryn E. Engelhardt, Bryan F. Meyers, Varun Puri, Benjamin D. Kozower
Summary: This study evaluated patient-reported pain, dyspnea, and functional status before and up to 1 year after lung cancer resection. The results showed that pain interference, physical function, and dyspnea severity scores were worse 1 month postoperatively. Pain interference and physical function scores returned to baseline by 6 months after surgery, but dyspnea severity scores remained persistently worse up to 1 year after surgery. Patients who underwent thoracotomy initially reported worse pain and physical function, but these impairments improved by 6 months after surgery.
JOURNAL OF THORACIC AND CARDIOVASCULAR SURGERY
(2022)
Article
Health Care Sciences & Services
Bregje D. Onwuteaka-Philipsen, H. Roeline W. Pasman, Ida J. Korfage, Erica Witkamp, Masha Zee, Liza G. G. van Lent, Anne Goossensen, Agnes van der Heide
Summary: This study described characteristics of patients who died and the care they received during the COVID-19 pandemic, finding that having COVID-19 was negatively associated with the evaluation of end-of-life care while having a serious chronic illness was positively associated. Visiting restrictions in the last 2 days of life were common among COVID-19 patients and were negatively related to the evaluation of care at the end of life and the dying process. Care at the end of life was less positively evaluated in hospitals and nursing homes compared to home settings and hospices, suggesting further optimization of end-of-life care during the pandemic, especially in nursing homes and hospitals. Allowance of some level of visits by relatives seems to be crucial.
PALLIATIVE MEDICINE
(2021)
Review
Medicine, General & Internal
Nicolas Paul, Elena Ribet Buse, Anna-Christina Knauthe, Monika Nothacker, Bjorn Weiss, Claudia D. Spies
Summary: ObjectiveCare bundles are important tools for improving bedside quality of care in the ICU. This study aimed to explore their impact on long-term patient-relevant outcomes. The results showed that the effects of these bundles on long-term outcomes are inconclusive.
Article
Geriatrics & Gerontology
Pamela Irwin, Deanne Taylor, Janice M. Keefe
Summary: This study analyzed policies related to the quality of life of long-term care residents in four Canadian provinces. It identified three key policy levers: situations, structures, and trajectories. The findings showed that certain policies prioritize safety and security, while others focus on resident-centered quality of life. These findings can inform resource utilization and improve long-term care in Canada.
Article
Multidisciplinary Sciences
Tetsuya Ito, Emi Tomizawa, Yuki Yano, Kiyozumi Takei, Naoko Takahashi, Fumio Shaku
Summary: This study investigated the impact of anxiety on cancer patients receiving palliative care, finding that patients with greater functional impairment and symptom control needs experienced more severe anxiety. Factors correlated with patient anxiety included symptoms, edema, and disabilities in daily living.
SCIENTIFIC REPORTS
(2021)
Article
Geriatrics & Gerontology
Emi Teraoka, Susumu Kunisawa, Yuichi Imanaka
Summary: This study examined the trajectories of end-of-life medical and long-term care expenditures in a large-scale linked database in Japan. It identified six distinct spending trajectories for total healthcare expenditures and found that most patients had high persistent spending patterns in their last 5 years. Factors such as chronic illnesses and organ failures were associated with higher spending trajectories, providing healthcare providers with insights into longer-term end-of-life care planning.
Article
Medicine, General & Internal
Pietro Alfano, Giuseppina Cuttitta, Palma Audino, Giovanni Fazio, Sabina La Grutta, Salvatore Marcantonio, Salvatore Bucchieri, Snamid Palermo Cooperative Grp
Summary: The study aimed to evaluate the mediating role of dyspnea perception in the relationship between multimorbidity and Quality of Life in both patients with and without airflow obstruction in a primary care setting.
JOURNAL OF CLINICAL MEDICINE
(2022)
Article
Obstetrics & Gynecology
Karishma P. Ramlakhan, Johanna A. van Der Zande, Jolien W. Roos-Hesselink, Arie Franx, Jerome Cornette
Summary: The study assessed the long-term quality of life after obstetric ICU admission and found that it is associated with reductions in physical and mental health. The findings suggest the need for multidisciplinary rehabilitation and long-term psychosocial support.
BJOG-AN INTERNATIONAL JOURNAL OF OBSTETRICS AND GYNAECOLOGY
(2023)
Article
Oncology
Hilde Van Parijs, Vincent Vinh-Hung, Christel Fontaine, Guy Storme, Claire Verschraegen, Dung M. Nguyen, Nele Adriaenssens, Nam P. Nguyen, Olena Gorobets, Mark De Ridder
Summary: Comparison between conventional radiotherapy and tomotherapy on long-term patient-reported outcomes (PRO) after breast cancer adjuvant radiotherapy showed that modern radiation therapy can significantly improve long-term PRO for patients.
Article
Pediatrics
Eleonore S. V. de Sonnaville, Marsh K. Konigs, Cornelieke S. H. Aarnoudse-Moens, Job B. M. van Woensel, Jaap Oosterlaan, Hennie Knoester
Summary: This study aimed to investigate the long-term impact of pediatric intensive care unit (PICU) admission on daily life functioning and the potential mediating role of neurocognitive outcome. The study compared children aged 6-12 years with previous PICU admission for bronchiolitis requiring mechanical ventilation to healthy peers. The results showed that children admitted to the PICU had poorer academic performance and school-related quality of life compared to the control group. Lower intelligence was found to contribute to academic difficulties after PICU admission. The findings highlight the importance of monitoring daily life and neurocognitive functioning after PICU admission.
JOURNAL OF PEDIATRICS
(2023)
Article
Health Care Sciences & Services
Leslye Rojas-Concha, Maiken Bang Hansen, Mathilde Adsersen, Morten Aagaard Petersen, Mogens Groenvold
Summary: This study evaluated the implementation of clinical guidelines in palliative care services in Denmark and found that the implementation was more successful for physical symptoms than for depression.
PALLIATIVE MEDICINE
(2023)
Article
Gerontology
Joseph W. June, Debra Dobbs, Victor Molinari, Hongdao Meng, John R. Bowblis, Kathryn Hyer
Summary: This study examines the factors associated with closure of assisted living facilities (ALFs) and finds that fewer beds, not accepting Medicaid, and more deficiencies are significant factors that increase the odds of closure. Market concentration and population density also have a marginal association with closure. The study highlights the impact of closure on community-based long-term care and suggests expanding Medicaid acceptance in ALFs as a protective measure against closure.
Article
Health Care Sciences & Services
Lisa DiMartino, Thomas Miano, Kathryn Wessell, Buck Bohac, Laura C. Hanson
Summary: This study evaluated the feasibility of using natural language processing (NLP) to identify symptom burden in hospitalized cancer patients using electronic health records (EHR). The results showed that NLP can be an effective method for identifying symptom burden, but further model development is needed.
JOURNAL OF PAIN AND SYMPTOM MANAGEMENT
(2022)
Article
Geriatrics & Gerontology
Joshua D. Niznik, Sarah D. Berry, Maggie Syme, Casey J. Kelley, Laura C. Hanson, Jill Harrison
Summary: COVID-19 vaccination rates are low among frontline healthcare assistants. Safety concerns are the primary contributors to vaccine hesitancy. Addressing short-term and long-term safety implications can effectively increase vaccination rates among healthcare assistants.
Article
Public, Environmental & Occupational Health
Joseph W. June, Lindsay Peterson, Kathryn Hyer, Debra Dobbs
Summary: This study aimed to explore the relationship between characteristics of nursing homes and assisted living facilities in Florida and their compliance with a new emergency power rule. The results suggest that certain characteristics, such as dementia care unit and reliance on Medicaid, are associated with compliance.
DISASTER MEDICINE AND PUBLIC HEALTH PREPAREDNESS
(2022)
Article
Gerontology
Tongda Sun, Rangcheng Jia, Jodie-Ann Clarke, Mingze Zhu, Debra Dobbs, Yuntong Di, Xiaoxin Dong, Hongdao Meng
Summary: This study describes the perceived and unmet needs for health and social services among families coping with dementia in urban China, and examines their relative importance. The findings highlight the wide range of services and supports needed by people living with dementia and their families to live in the community.
DEMENTIA-INTERNATIONAL JOURNAL OF SOCIAL RESEARCH AND PRACTICE
(2022)
Article
Gerontology
Britney M. Veal, Debra Dobbs, Soomi Lee, Jennifer A. Bugos, Mary P. Pyfrom, Samantha Boddupalli, Cecile A. Lengacher, Hongdao Meng
Summary: This study aimed to examine the feasibility and acceptability of a group music intervention in reducing agitation among persons with dementia. The results showed that the majority of participants completed the intervention and 63.2% experienced a reduction in agitation. Therefore, this intervention is feasible and acceptable in memory care and may be efficacious.
JOURNAL OF APPLIED GERONTOLOGY
(2022)
Article
Oncology
Eliza M. Park, Allison M. Deal, Hillary M. Heiling, Ahrang Jung, Justin M. Yopp, Savannah M. Bowers, Laura C. Hanson, Mi-Kyung Song, Carmina G. Valle, Brian Yi, Anna Cassidy, Hannah Won, Donald L. Rosenstein
Summary: The study assessed the feasibility, acceptability, and preliminary effects of Families Addressing Cancer Together (FACT), a web-based intervention for parents with cancer to talk with their children. Most participants found FACT helpful, relevant, and easy to understand, with potential to address communication concerns of parents with cancer.
SUPPORTIVE CARE IN CANCER
(2022)
Article
Geriatrics & Gerontology
Hillary J. Rouse, Cassidy Doyle, Gizem Hueluer, Mia D. Torres, Lindsay J. Peterson, Xi Pan, Debra Dobbs, Yan Du, Kyaien Conner, Hongdao Meng
Summary: This study aimed to examine the association between music engagement and episodic memory in middle- and older-aged adults in the United States over a period of 12 years. The results showed that participants who reported both passive and active music engagement performed better on episodic memory tasks compared to those with no music engagement. Participants with passive music engagement also had slower decline in memory scores. Further research is needed to investigate the impact of community-based music engagement interventions on memory decline.
JOURNALS OF GERONTOLOGY SERIES B-PSYCHOLOGICAL SCIENCES AND SOCIAL SCIENCES
(2023)
Article
Gerontology
Lindsay J. Peterson, Sara E. Hackett, Debra Dobbs, William E. Haley
Summary: This study aimed to understand the disaster preparedness of caregivers of persons with dementia in order to provide guidance for future interventions. The study found that disaster preparedness was challenging for caregivers but also perceived as an important responsibility. The study recommends providing more resources for caregivers to cope with the stressors associated with disaster preparedness.
Article
Gerontology
Debra Dobbs, Jessica Yauk, Carlyn E. Vogel, Dany Fanfan, Harleah Buck, William E. Haley, Hongdao Meng
Summary: This study aims to identify effective interventions for delivering palliative care to residents with dementia in assisted living facilities. A pilot study was conducted in 10 ALs in Florida, showing promising results in terms of feasibility and efficacy. However, a larger randomized trial is needed to further test its effectiveness.
Review
Geriatrics & Gerontology
Jennifer L. Gabbard, Joan G. Carpenter, Natalie C. Ernecoff, Kimberly Mournighan, Isabella Cornea, Mark McKone, Laura C. Hanson
Summary: This study conducted a scoping review of outcome measures utilized in ACP randomized controlled clinical trials, evaluating their pragmatic characteristics. The results showed that only 23% of the outcome measures were highly pragmatic, and the majority of these measured healthcare utilizations. New outcome measures that address the lived experience of persons living with dementia and their care partners are needed.
JOURNAL OF THE AMERICAN GERIATRICS SOCIETY
(2023)
Article
Geriatrics & Gerontology
Laura C. Hanson, Kathryn Wessell, Natalie Meeks, Antonia V. Bennett, Mark Toles, Josh Niznik, Sheryl Zimmerman, Joan Carpenter, Christine S. Ritchie, Natalie C. Ernecoff, Debra Saliba
Summary: This study describes the development and structure of the IMbedded Pragmatic ADRD Clinical Trials Collaboratory (IMPACT) iLibrary of potential outcome measures for ADRD pragmatic trials and evaluates their pragmatic characteristics. The study found that pragmatic outcome measures are brief, meaningful to diverse populations, easily scored and interpreted by clinicians, and available in electronic format for analysis. The iLibrary can aid in the selection of measures for a wide range of outcomes relevant to people with ADRD and their care partners.
JOURNAL OF THE AMERICAN GERIATRICS SOCIETY
(2023)
Article
Geriatrics & Gerontology
Antonia V. Bennett, Kyra O'Brien, Monica Moreno, Kerry Lanigan, Katie Maslow, Carolyn A. Malone, Laura C. Hanson, Sheryl Zimmerman, Jason Karlawish, Emily A. Largent, Maria P. Aranda, Ladson Hinton, Brenda P. Nicholson, Louise Phillips, Sam Fazio, Gary Epstein-Lubow
Summary: The National Institute on Aging convened a Lived Experience Panel to provide input on research priorities and conducting clinical trials of dementia care interventions. In its first year, the panel met with different cores of the IMPACT Collaboratory and offered valuable insights and discussions on issues relevant to dementia care.
JOURNAL OF THE AMERICAN GERIATRICS SOCIETY
(2023)
Article
Health Care Sciences & Services
Anne M. Walling, Katherine Ast, Jordan M. Harrison, Sydney M. Dy, Mary Ersek, Laura C. Hanson, Arif H. Kamal, Christine S. Ritchie, Joan M. Teno, Joseph D. Rotella, Vyjeyanthi S. Periyakoil, Sangeeta C. Ahluwalia
Summary: This study developed and tested two patient-reported measures to assess the quality of Palliative care. The development process involved patient engagement and feedback. The measures addressed the gaps in research and received endorsement from the National Quality Forum.
JOURNAL OF PAIN AND SYMPTOM MANAGEMENT
(2023)
Article
Medicine, Research & Experimental
Meghan Hendricksen, Andrea J. Loizeau, Daniel A. Habtemariam, Ruth A. Anderson, Laura C. Hanson, Erika M. C. D'Agata, Susan L. Mitchell
Summary: This study examined facility and provider characteristics associated with adherence to the TRAIN-AD program. The results showed that being a nurse was associated with higher likelihood of attending training seminars, while providers who were in facilities when implementation began and in facilities with better quality ratings were more likely to complete the online course. Prevalent participation and higher facility quality were also significantly associated with greater adherence to either seminar or online course.
CONTEMPORARY CLINICAL TRIALS COMMUNICATIONS
(2022)