Direct Inhibition of Cellular Fatty Acid Synthase Impairs Replication of Respiratory Syncytial Virus and Other Respiratory Viruses

Abstract 801: Sensitivity of cell lines to Fatty Acid Synthase inhibitors depends on the lipid content in the cellular environment

(2015) Karine A. Smans et al.   CANCER RESEARCH

Cancer Cells Differentially Activate and Thrive on De Novo Lipid Synthesis Pathways in a Low-Lipid Environment

(2014) Veerle W. Daniëls et al.   PLoS One

Nutrient-dependent phosphorylation channels lipid synthesis to regulate PPARα

(2013) Anne P. L. Jensen-Urstad et al.   JOURNAL OF LIPID RESEARCH

Differential Regulation of Host Genes Including Hepatic Fatty Acid Synthase in HBV-Transgenic Mice

(2013) Hongmin Zhang et al.   JOURNAL OF PROTEOME RESEARCH

Hepatitis C Virus Replication Is Modulated by the Interaction of Nonstructural Protein NS5B and Fatty Acid Synthase

(2013) J.-T. Huang et al.   JOURNAL OF VIROLOGY

Hsp90 Inhibitors Exhibit Resistance-Free Antiviral Activity against Respiratory Syncytial Virus

(2013) Ron Geller et al.   PLoS One

Palmitoylation of virus proteins

(2012) Michael Veit   BIOLOGY OF THE CELL

Imidazopyridine-Based Fatty Acid Synthase Inhibitors That Show Anti-HCV Activity and in Vivo Target Modulation

(2012) Johan D. Oslob et al.   ACS Medicinal Chemistry Letters

Cholesterol-Rich Microdomains as Docking Platforms for Respiratory Syncytial Virus in Normal Human Bronchial Epithelial Cells

(2011) H. San-Juan-Vergara et al.   JOURNAL OF VIROLOGY

Blockade of Fatty Acid Synthase Induces Ubiquitination and Degradation of Phosphoinositide-3-Kinase Signaling Proteins in Ovarian Cancer

(2011) K. Tomek et al.   MOLECULAR CANCER RESEARCH

Identification of nucleolin as a cellular receptor for human respiratory syncytial virus

(2011) Farnoosh Tayyari et al.   NATURE MEDICINE

Cholesterol-rich lipid rafts are required for release of infectious human respiratory syncytial virus particles

(2011) Te-Hung Chang et al.   VIROLOGY

Progress in understanding and controlling respiratory syncytial virus: Still crazy after all these years

(2011) Peter L. Collins et al.   VIRUS RESEARCH

Caveolin-1 interacts with a lipid raft-associated population of fatty acid synthase

(2010) Dolores Di Vizio et al.   CELL CYCLE

Global burden of acute lower respiratory infections due to respiratory syncytial virus in young children: a systematic review and meta-analysis

(2010) Harish Nair et al.   LANCET

Dengue virus nonstructural protein 3 redistributes fatty acid synthase to sites of viral replication and increases cellular fatty acid synthesis

(2010) N. S. Heaton et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Novel Inhibitors of Fatty Acid Synthase with Anticancer Activity

(2009) T. Puig et al.   CLINICAL CANCER RESEARCH

Importance of viral and bacterial infections in chronic obstructive pulmonary disease exacerbations

(2009) Gaston De Serres et al.   JOURNAL OF CLINICAL VIROLOGY

Inhibition of fatty acid synthase by luteolin post-transcriptionally down-regulates c-Met expression independent of proteosomal/lysosomal degradation

(2009) D. T. Coleman et al.   MOLECULAR CANCER THERAPEUTICS

Evidence that selective changes in the lipid composition of raft-membranes occur during respiratory syncytial virus infection

(2009) Dawn Su-Yin Yeo et al.   VIROLOGY