Article
Radiology, Nuclear Medicine & Medical Imaging
Junhan Pan, Mengchen Song, Lili Yang, Yanci Zhao, Yanyan Zhu, Meng Wang, Feng Chen
Summary: This study evaluated the value of using EC or modified capsule appearance in LI-RADS for diagnosing HCC <= 3.0 cm on Gd-EOB-MRI, and explored the relationship between imaging features and the histological fibrous capsule. The results showed that EC appearance improved the diagnostic sensitivity of LI-RADS for HCC, and considering NEC as an alternative capsule appearance allowed for better inter-reader reliability and comparable diagnostic ability.
EUROPEAN RADIOLOGY
(2023)
Article
Radiology, Nuclear Medicine & Medical Imaging
Jerome Hodel, Meike W. Vernooij, Mona K. Beyer, Mariasavina Severino, Xavier Leclerc, Alain Creange, Abir Wahab, Neesmah Badat, Sarah Toledano, Luc van den Hauwe, Ana Ramos, Antonella Castellano, Alexandre Krainik, Tarek Yousry, Alex Rovira
Summary: This study evaluated compliance with recommendations in imaging for multiple sclerosis (MS). The results showed that while MS imaging practices are relatively consistent across Europe, there is still partial adherence to recommendations.
EUROPEAN RADIOLOGY
(2023)
Article
Radiology, Nuclear Medicine & Medical Imaging
Hongfei Lu, Jiajun Guo, Shihai Zhao, Shan Yang, Jianying Ma, Meiying Ge, Yinyin Chen, Mengsu Zeng, Hang Jin
Summary: This study evaluated the performance of 3.0 T non-contrast-enhanced Dixon water-fat separation CS whole-heart CMRA sequence and found it to be a promising noninvasive and radiation-free technique for detecting clinically significant coronary stenosis in patients with suspected CAD.
ACADEMIC RADIOLOGY
(2022)
Article
Radiology, Nuclear Medicine & Medical Imaging
Isabelle Riederer, Mark Muehlau, Claus Zimmer, Magaly Gutbrod-Fernandez, Nico Sollmann, Jan S. Kirschke
Summary: The study found that pre-contrast T1-w imaging does not significantly increase diagnostic confidence or detection rate of contrast-enhancing lesions in spinal cord MRI follow-up exams for patients with multiple sclerosis (MS).
EUROPEAN RADIOLOGY
(2021)
Article
Radiology, Nuclear Medicine & Medical Imaging
Michal Rivlin, Debbie Anaby, Noam Nissan, Moritz Zaiss, Anagha Deshmane, Gil Navon, Miri Sklair-Levy
Summary: The feasibility of using GlcN CEST MRI technique to distinguish between tumor and surrounding tissue in diagnosing breast cancer in a clinical setting is indicated by the results of this initial study.
EUROPEAN RADIOLOGY
(2022)
Article
Cardiac & Cardiovascular Systems
Keyan Wang, Wenbo Zhang, Shuman Li, Xiaoming Bi, Michaela Schmidt, Jing An, Jie Zheng, Jingliang Cheng
Summary: The study explored the use of a free-breathing CMR protocol in patients with coronary heart disease, assessing prognosis by calculating infarction size and left ventricular ejection fraction. Results showed that these values were significantly associated with major adverse cardiovascular events.
BMC CARDIOVASCULAR DISORDERS
(2021)
Article
Engineering, Biomedical
Gary Stinnett, Nasim Taheri, Jake Villanova, Arash Bohloul, Xiaoting Guo, Edward P. Esposito, Zhen Xiao, Deanna Stueber, Carolina Avendano, Paolo Decuzzi, Robia G. Pautler, Vicki L. Colvin
Summary: This study introduces shape-engineered plate-like nanocrystals with sulfonated surface polymers that promote second-sphere relaxation processes, providing remarkable contrast even at high fields. These noncytotoxic materials release no detectable free Gadolinium even under mild acidic conditions, and have a circulation half-life in the liver 50% longer than commercial agents. These features enable the first-time application of T-1 MRI contrast agents to the ex vivo detection of nonalcoholic fatty liver disease in mice.
ADVANCED HEALTHCARE MATERIALS
(2021)
Review
Oncology
Federico Bruno, Vincenza Granata, Flavia Cobianchi Bellisari, Ferruccio Sgalambro, Emanuele Tommasino, Pierpaolo Palumbo, Francesco Arrigoni, Diletta Cozzi, Francesca Grassi, Maria Chiara Brunese, Silvia Pradella, Maria Luisa Mangoni di S. Stefano, Carmen Cutolo, Ernesto Di Cesare, Alessandra Splendiani, Andrea Giovagnoni, Vittorio Miele, Roberto Grassi, Carlo Masciocchi, Antonio Barile
Summary: This article introduces the application of magnetic resonance imaging in the field of nanomedicine and the characteristics of nanoparticles as diagnostic and therapeutic tools. Imaging techniques play an important role in studying the properties of nanoconstructs and their interactions with the biological environment.
Article
Medicine, General & Internal
Ou Ou Yang, Tian Lan, Jun Ling He, Hai Bin Xu, Liang Hao, Chang Shu, Zu Jian Hu, Hua Luo
Summary: Primary breast angiosarcoma is a rare and aggressive entity that is difficult to diagnose, leading to recurrence and metastasis. Combining contrast-enhanced ultrasound and MRI can help in the diagnosis of breast angiosarcomas.
Review
Chemistry, Multidisciplinary
Mike Jeon, Mackenzie Halbert, Zachary R. Stephen, Miqin Zhang
Summary: Gadolinium-based chelates are commonly used contrast agents for MRI, but their toxicity and potential retention in patients' bodies have raised safety concerns. Iron oxide nanoparticles have emerged as a promising alternative due to their non-toxic and biodegradable nature, but their development as T-1 contrast agents is complex and challenging. Progress is being made in exploring IONPs as safe and improved alternatives, but there are still many hurdles to overcome before they can be used clinically.
ADVANCED MATERIALS
(2021)
Article
Cardiac & Cardiovascular Systems
Hongfei Lu, Shihai Zhao, Di Tian, Yinyin Chen, Jianying Ma, Meiying Ge, Mengsu Zeng, Hang Jin
Summary: This study aimed to investigate the clinical application of coronary MR angiography (MRA) in coronary artery disease (CAD) patients and design an optimal scan protocol to evaluate its diagnostic performance and feasibility to measure coronary distensibility index (CDI) noninvasively.
JOURNAL OF CARDIOVASCULAR MAGNETIC RESONANCE
(2023)
Article
Cardiac & Cardiovascular Systems
Gemma A. Figtree, Philip D. Adamson, Charalambos Antoniades, Roger S. Blumenthal, Michael Blaha, Matthew Budoff, David S. Celermajer, Mark Y. Chan, Clara K. Chow, Damini Dey, Girish Dwivedi, Nicola Giannotti, Stuart M. Grieve, Christian Hamilton-Craig, Bronwyn A. Kingwell, Jason C. Kovacic, James K. Min, David E. Newby, Sanjay Patel, Karlheinz Peter, Peter J. Psaltis, Stephen T. Vernon, Dennis T. Wong, Stephen J. Nicholls
Summary: Coronary artery disease (CAD) is the leading cause of adult mortality globally. Improvements in imaging techniques have provided a better understanding of different phenotypes of coronary atherosclerosis, which are associated with different risks for acute ischemic events. Noninvasive coronary imaging techniques have the potential to accelerate cardiovascular drug development and reduce costs and timelines.
Article
Radiology, Nuclear Medicine & Medical Imaging
E. Reizine, M. Ronot, M. Ghosn, J. Calderaro, N. Frulio, P. Bioulac-Sage, H. Trillaud, V. Vilgrain, V Paradis, A. Luciani
Summary: The uptake of hepatospecific contrast agent on hepatobiliary phase is strongly associated with marked activation of the beta-catenin pathway in hepatocellular adenomas, suggesting its potential for improving subtype classification of hepatocellular adenomas on MRI.
EUROPEAN RADIOLOGY
(2021)
Article
Multidisciplinary Sciences
Robert Siepmann, Henning Nilius, Florian Mueller, Katrin Mueller, Claudio Luisi, Seyed Mohammadali Dadfar, Marcel Straub, Volkmar Schulz, Sebastian Daniel Reinartz
Summary: The study evaluated whether MPI could measure coronary blood velocities and calculate CFR, showing that MPI can reliably measure coronary blood velocities at rest and under hyperaemia, but the accuracy of CFR calculation needs substantial improvement.
Article
Multidisciplinary Sciences
Gabriella Hernadi, David Pinter, Szilvia Anett Nagy, Gergely Orsi, Samuel Komoly, Jozsef Janszky, Norbert Kovacs, Gabor Perlaki
Summary: The study compared different MRI sequences for nigral hyperintensity imaging and found that EPISEG performed the best in reducing motion artifacts, increasing radiologist confidence, and lowering the rate of non-diagnostic scans.
SCIENTIFIC REPORTS
(2021)
Article
Surgery
Yangzi Zhu, Meiyan Zhou, Xiuqin Jia, Wei Zhang, Yibing Shi, Shengjie Bai, Sanketh Rampes, Marcela P. Vizcaychipi, Congyou Wu, Kai Wang, Daqing Ma, Qi Yang, Liwei Wang
Summary: The goal of this study was to investigate the changes in functional connectivity (FC) after cardiac surgery and its relationship with cognitive deficits and systemic inflammation. Seventeen patients who underwent cardiac valve replacement and age-matched healthy controls were included in the study. Results showed that executive function was significantly impaired after cardiac surgery. The surgical patients demonstrated decreased FC within the executive control network and attenuated negative connectivity in the default mode network, which were related to increased tumor necrosis factor-a levels and decreased executive function up to day 7 after surgery.
Article
Neuroimaging
Song Tan, Yuzhao Lu, Bin Li, Qi Yang, Xiaobing Zhou, Yang Wang
Summary: This study aimed to prospectively evaluate the diagnostic performance of silent MRA in the follow-up of intracranial aneurysms treated by different interventional approaches. The results showed that silent MRA demonstrated excellent performance in visualizing the treated sites and evaluating the occlusion status of the aneurysms. Therefore, silent MRA may be an ideal option for repeated examinations.
JOURNAL OF NEUROINTERVENTIONAL SURGERY
(2023)
Article
Clinical Neurology
Min Li, Xiaogang Gao, Qi Yang, Xuxiang Zhang, Jian Chen, Ran Meng, Xunming Ji
Summary: This multicenter prospective cohort study aims to fill the gap in epidemiological data on cerebral venous thrombosis in China and provide strong evidence on the incidence rate, recurrence rate, demographic data, clinical outcomes, and special risk factors of this disease in the Chinese population.
CEREBROVASCULAR DISEASES
(2023)
Editorial Material
Radiology, Nuclear Medicine & Medical Imaging
Jin Li, Zhaoyang Fan, Qi Yang
JOURNAL OF MAGNETIC RESONANCE IMAGING
(2023)
Article
Neurosciences
Yingying Li, Xin Liu, Xuejia Jia, Haoyuan Li, Xiuqin Jia, Qi Yang
Summary: This study used a meta-analysis to identify stable brain structural and neuronal functional abnormalities in patients with cerebral small vessel disease (CSVD). The findings provide insights into the pathogenesis of CSVD and CSVD-related cognitive impairment, as well as offer an index to evaluate the effectiveness of treatment protocols.
Article
Neuroimaging
Xiuqin Jia, Chen Ling, Yingying Li, Jinyuan Zhang, Zhixin Li, Xuejia Jia, Danny J. J. Wang, Zihao Zhang, Yun Yuan, Qi Yang
Summary: Brain damage caused by small vessel disease (SVD) differs between males and females. This study aimed to investigate the sex-specific neuroanatomical mechanisms of SVD by adjusting for the effects of age and sex on healthy brain volume. Male CADASIL patients showed significant cognitive declines and greater gray matter atrophy compared to female patients, specifically in the orbitofrontal cortex (OFC), anterior cingulate cortex (ACC), entorhinal cortex (EC), and temporooccipital cortex. Working memory was associated with volumes in the right OFC in female CADASIL patients, while visuospatial ability was associated with the right hOcl volume in males. These findings highlight the importance of considering sex differences in the pathogenesis and treatment of CADASIL and SVD.
NEUROIMAGE-CLINICAL
(2023)
Article
Medicine, General & Internal
Ji-Fang He, Yi-Xing Yang, Jiang-Yuan Li, Lu Liang, Li Xu, Yu Liu, Zong-Sheng Guo, Qi Yang, Tao Jiang, Xiang-Min Lin, Xin-Chun Yang, Mu-Lei Chen, Pi-Xiong Su, Jiu-Chang Zhong, Le-Feng Wang
Summary: The VCR strategy for PCI in patients with STEMI is feasible and safe.
JOURNAL OF CLINICAL MEDICINE
(2023)
Article
Radiology, Nuclear Medicine & Medical Imaging
Xiaojuan Guo, Mingxi Liu, Juanni Gong, Yuanhua Yang, Min Liu, Wenhuan Li, Qi Yang
Summary: In patients with Takayasu arteritis (TAK) and preserved left ventricular ejection fraction (pLVEF), both global and segmental myocardial strain decreased. Pulmonary hypertension (PH), male gender, long disease duration, elevated erythrocyte sedimentation rate (ESR), and myocardial late gadolinium enhancement (LGE) were associated with declined left ventricular strain. Baseline increased circumferential diastolic peak strain rates (DPSR) may be associated with the decline in LVEF during follow-up.
QUANTITATIVE IMAGING IN MEDICINE AND SURGERY
(2023)
Article
Radiology, Nuclear Medicine & Medical Imaging
Xiaojuan Guo, Min Liu, Mingxi Liu, Zhanhong Ma, Juanni Gong, Yuanhua Yang, Wei Gao, Jiaoyan Wu, Qi Y. Ang, Min-Fu Yang
Summary: This study aimed to compare the value of DE-MRI with 18F-FDG PET/CT in the evaluation of pulmonary artery lesions in Takayasu's arteritis (TAK). The results showed that DE-MRI had good correlations with PET/CT findings and performed better in thoracic aorta than in the pulmonary artery. Combining DE with erythrocyte sedimentation rate (ESR) improved the efficiency of assessing disease status.
QUANTITATIVE IMAGING IN MEDICINE AND SURGERY
(2023)
Article
Radiology, Nuclear Medicine & Medical Imaging
Xiao-Yi Guo, Hyeok Jung Kwon, Hak Young Rhee, Soonchan Park, Ah Rang Cho, Chang-Woo Ryu, Geon-Ho Jahng
Summary: This study used MRI with contrast agent to detect microvascular alterations in AD patients. The results showed increased BVf and MvWI in the AD group. The correlation between these values and age was also evaluated. These indexes can be used to non-invasively evaluate microvascular morphology alterations in AD patients.
QUANTITATIVE IMAGING IN MEDICINE AND SURGERY
(2023)
Article
Clinical Neurology
Xiaoxu Yang, Pengxin Yu, Haoyue Zhang, Rongguo Zhang, Yuehong Liu, Haoyuan Li, Penghui Sun, Xin Liu, Yu Wu, Xiuqin Jia, Jiangang Duan, Xunming Ji, Qi Yang
Summary: This study developed and evaluated a novel deep learning algorithm for detecting cerebral venous thrombosis (CVT) using routine brain magnetic resonance imaging. The algorithm achieved high sensitivity and specificity, improving the diagnostic performance of routine brain magnetic resonance imaging for CVT detection.
Article
Medicine, General & Internal
Hongyu Gao, Yueyan Bian, Gen Cheng, Huan Yu, Yuze Cao, Huixue Zhang, Jianjian Wang, Qian Li, Qi Yang, Lihua Wang
Summary: This study developed a deep learning approach based on CTP or PWI to identify a 6-hour window for endovascular thrombectomy (EVT) in patients with acute ischemic stroke (AIS). The classifier had higher performance compared to other machine learning algorithms, and it showed potential in accurately estimating the stroke onset time of patients with wake-up stroke (WUS).
FRONTIERS IN MEDICINE
(2023)
Article
Public, Environmental & Occupational Health
Haibin Li, Jiajia Zhang, Xinye Zou, Xiuqin Jia, Deqiang Zheng, Xiuhua Guo, Wuxiang Xie, Qi Yang
Summary: This study examined the longitudinal bidirectional association between gait speed and cognitive function in older Chinese adults. It found that baseline cognitive function had a stronger association with subsequent gait speed than the reverse. This interlinkage is noteworthy and suggests that maintaining normal cognitive function may be an important intervention strategy for mitigating age-related gait speed reduction.
JMIR PUBLIC HEALTH AND SURVEILLANCE
(2023)
Article
Geriatrics & Gerontology
Jiajia Zhang, Xiuqin Jia, Yingying Li, Deqiang Zheng, Xiuhua Guo, Haibin Li, Qi Yang
Summary: The study found that higher baseline serum uric acid levels were associated with better baseline cognition and slower subsequent cognitive decline among Chinese adults. Furthermore, there was an indirect association between baseline serum uric acid and subsequent cognition through the mediating effect of baseline depressive symptoms.
JOURNALS OF GERONTOLOGY SERIES A-BIOLOGICAL SCIENCES AND MEDICAL SCIENCES
(2023)
Article
Radiology, Nuclear Medicine & Medical Imaging
Chen Ling, Jinyuan Zhang, Xingfeng Shao, Li Bai, Zhixin Li, Yunchuang Sun, Fan Li, Zhaoxia Wang, Rong Xue, Yan Zhuo, Qi Yang, Zihao Zhang, Danny J. J. Wang, Yun Yuan
Summary: This study found that the BBB water exchange rate was decreased in patients with CADASIL. The decreased rate was associated with increased MRI lesion burden and functional dependence of the patients, suggesting the involvement of BBB dysfunction in the pathogenesis of CADASIL.
EUROPEAN RADIOLOGY
(2023)
