Article
Chemistry, Analytical
Tingting Zhao, Yuhuan Gao, Jun Wang, Yanyun Cui, Shuyan Niu, Shenghao Xu, Xiliang Luo
Summary: The near-infrared light-activated intelligent nanoprobe can accurately image multiple intracellular miRNAs on demand, effectively avoiding false-positive signals and improving imaging accuracy. This technology shows feasibility in precise imaging and disease diagnosis.
ANALYTICAL CHEMISTRY
(2021)
Article
Chemistry, Multidisciplinary
Mariam Bayoumi, Stefanos K. Nomidis, Kherim Willems, Enrico Carlon, Giovanni Maglia
Summary: The synthetic nanoscale piston presented in the study uses chemical energy to transport molecules against applied bias, allowing for selected DNA molecules to be transported across a nanopore through hybridization and strand displacement reactions. The device demonstrates multiple automated and reciprocating cycles without the need for external bias force, exhibiting characteristics of biological transporters.
Article
Chemistry, Physical
Qiong Yang, Jingjing Wang, Haoran Wu, Shaoxiong Qin, Jiaqi Pan, Chaorong Li
Summary: In this study, a hierarchically rough CuO/Ag composite film with good SERS performance and recyclability was prepared by loading silver nanoparticles onto a copper oxide film with hierarchical micro/nanostructures. The CuO/Ag composite substrate can degrade surface adsorbed molecules under light irradiation, achieving self-cleaning and reusable. With the optimized composite film as the SERS active substrate, low detection limits for R6G and CV molecules were achieved. The hierarchical CuO/Ag composite film has great potential for efficient SERS sensors.
APPLIED SURFACE SCIENCE
(2022)
Article
Nanoscience & Nanotechnology
X. Hai, M. Ji, K. Yu, T. Tian, Z. Cui, S. Bi, X. Zhang
Summary: DNA nanotechnology has been utilized to construct a DNA-Au nanomachine with active/passive dual-targeting capacity for lysosomal acidic microenvironment-activated combinational chemo-photothermal therapy of cervical carcinoma. The nanomachine consists of three-dimensional DNA nanoflowers and BSA-modified gold nanoparticles, allowing for targeted chemotherapy and photothermal therapy. In vitro and in vivo studies demonstrate the potential of this nanomachine for targeted combinational therapy of cancer.
MATERIALS TODAY NANO
(2023)
Article
Biochemistry & Molecular Biology
Jingjing Wu, Jianfeng Xi, Haibo Chen, Yishan Liu, Lei Zhang, Peng Li, Weibing Wu
Summary: A flexible SERS substrate was developed for the detection of malachite green bactericide. The substrate was prepared by in situ photochemical synthesis of silver nanoparticles on a nanocellulose film. The obtained composite SERS substrate showed high sensitivity and good detection reproducibility to Rhodamine 6G and malachite green. This nanocellulose-based 2D SERS substrate has the potential for rapid and sensitive identification of various toxic and harmful pollutants.
INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES
(2022)
Article
Chemistry, Multidisciplinary
Arnab Mukherjee, Ambroise de Izarra, Jeril Degrouard, Enrick Olive, Prabal K. Maiti, Yun Hee Jang, Yves Lansac
Summary: The process of packaging the paternal genome into tiny sperm nuclei during spermatogenesis involves a high level of DNA compaction, mainly mediated by protamine, but the exact mechanism remains unclear. Research has shown that DNA condensates formation can be reversibly controlled by adjusting the protamine-to-DNA ratio, providing valuable insights for understanding early and intermediate stages of spermatogenesis. This reversible microscopic mechanism induced by protamination modulation could also potentially improve the efficiency of recent vaccines using protamine for virus infections and cancers.
Article
Chemistry, Multidisciplinary
Jun-Ge Li, Meng-Yin Li, Xin-Yi Li, Xue-Yuan Wu, Yi-Lun Ying, Yi-Tao Long
Summary: This study improves the resolution of nanopores by controlling the full width at half maximum (fwhm) of current blockage and establishes a correlation between fwhm and duration. It provides a new strategy for molecular sensing using nanopores.
Article
Chemistry, Multidisciplinary
Vasyl Shvalya, Aswathy Vasudevan, Martina Modic, Mohammad Abutoama, Cene Skubic, Nejc Nadizar, Janez Zavasnik, Damjan Vengust, Aleksander Zidansek, Ibrahim Abdulhalim, Damjana Rozman, Uros Cvelbar
Summary: Surface-enhanced Raman spectroscopy (SERS) can identify bacteria based on their genomic DNA composition. Spectral differentiation of bacterial species was achieved using nanogold aggregates, allowing SERS probing at nanogram sample quantities. Molecular fingerprints and nitrogenous base content estimation confirmed the genomic composition.
Article
Materials Science, Multidisciplinary
Rahul Prajesh, Rakesh Kumar Saini, Ashok Kumar Sharma, Ajay Agarwal
Summary: Thiram is a fungicide with health-related issues when consumed regularly. Monitoring its presence in food and vegetables is crucial. This study aims to develop a low-cost and simple label-free SERS active substrate for detecting low-level concentrations of Thiram.
MATERIALS CHEMISTRY AND PHYSICS
(2023)
Article
Spectroscopy
Mohammad Kamal Hossain, Qasem Ahmed Drmosh
Summary: Plasmonic nanostructures, particularly irregular surfaces of silver nanorings, have shown promise in surface-enhanced Raman scattering (SERS) spectroscopy. Through the fabrication and characterization of clusters-based Ag nanorings, it was found that they could achieve SERS enhancement factors as high as 2.1 x 10^4. By simulating EM near-field distributions and investigating the irregular shapes and arrangements of clusters within the nanorings, a deeper understanding of the underlying EM mechanism in SERS enhancements was gained.
SPECTROCHIMICA ACTA PART A-MOLECULAR AND BIOMOLECULAR SPECTROSCOPY
(2021)
Article
Biochemistry & Molecular Biology
Tasneem Elamin, Hans Brandstetter, Elfriede Dall
Summary: This study investigates the regulatory mechanisms of Legumain enzyme activity, substrate structures, and conformations. The research reveals that extended active site residues and substrate conformation can influence the protease and ligase activities of Legumain. Understanding these mechanisms is important for designing proteases with enhanced enzymatic activity and improved ligase substrates.
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
(2022)
Article
Nanoscience & Nanotechnology
Chuanshen Han, Yisheng Wei, Fengcai Lei, Shulong Zhao, Yumeng Wang, Chonghui Li, Shuai Su, Chao Zhang, Zhen Li, Jing Yu
Summary: This study presents a wettability-switchable SERS structure with impressive performance under both hydrophobic and hydrophilic states, showing potential for trace detection. Mechanism is revealed and quantifiability is demonstrated.
Article
Chemistry, Analytical
Tingting Zhang, Liyun Wu, Junchang Pei, Xuefeng Li, Haowen Li, Frank Inscore
Summary: In this study, we developed a portable method for detecting caffeine using surface-enhanced Raman spectroscopy (SERS). The results showed that this method has high sensitivity, can detect caffeine at low concentrations, and has good stability and reproducibility.
Article
Biochemistry & Molecular Biology
Lina Yao, Yanjie Li, Zhenzhong Zuo, Ziyi Gong, Jie Zhu, Xiaoqiang Feng, Dan Sun, Kaige Wang
Summary: In this study, the interaction properties of the anticancer drug BENDA with ctDNA were investigated using surface-enhanced Raman spectroscopy, UV-visible spectroscopy, and molecular docking simulation. The results showed that BENDA binds to ctDNA through covalent binding and hydrogen bonding, with the N7 atom of G base as the main binding site. This study helps to understand the mechanism of BENDA at the single-molecule level and provides guidance for the development of effective new drugs with low toxicity and side effects.
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
(2023)
Article
Biochemistry & Molecular Biology
Yuanqi Jing, Remigio Usai, Yilin Liu, James R. Kincaid
Summary: This study investigates the active site structure of CYP51 enzyme in the presence of its hydroxylase and lyase substrates using Resonance Raman spectroscopy and Nanodisc technology. The results show that the hydroxyl group of the lyase substrate interacts directly with the iron center, while a water ligand coordinated to the heme iron is retained, leading to a low degree of spin conversion in CYP51. The nanodisc-incorporated assemblies provide more well-defined active site responses and induce a larger spin conversion.
JOURNAL OF INORGANIC BIOCHEMISTRY
(2023)
Article
Chemistry, Multidisciplinary
Wei Tan, Hatim Alsenani, Shaohua Xie, Yandi Cai, Peng Xu, Annai Liu, Jiawei Ji, Fei Gao, Lin Dong, Ewa Chukwu, Ming Yang, Fudong Liu
Article
Engineering, Biomedical
Richard Johnson, Michael Rafuse, Prakash Parthiban Selvakumar, Wei Tan
Summary: This study evaluated the impacts of allogeneic bone marrow-derived stromal cells and recipient age on the long-term remodeling of vascular grafts. The results showed significant effects of these factors on graft outcomes. Additionally, compared to acellular grafts, cellular grafts showed efficient recruitment of vascular cells to form more organized structures.
ACTA BIOMATERIALIA
(2021)
Article
Chemistry, Physical
Yaxin Yu, Wei Tan, Dongqi An, Xiuwen Wang, Annai Liu, Weixin Zou, Changjin Tang, Chengyan Ge, Qing Tong, Jingfang Sun, Lin Dong
Summary: Research has shown that SO2 poisoning of NH3-SCR catalysts at low temperature remains a challenge. The formation of sulfate species inhibits the adsorption of NOx, while the formation of ferric sulfate enhances surface acidity, leading to an increase in catalytic activity.
APPLIED CATALYSIS B-ENVIRONMENTAL
(2021)
Article
Engineering, Environmental
Wei Tan, Annai Liu, Shaohua Xie, Yong Yan, Thomas E. Shaw, Yu Pu, Kai Guo, Lulu Li, Shuohan Yu, Fei Gao, Fudong Liu, Lin Dong
Summary: Investigating catalytic reaction mechanisms can guide catalyst design, as demonstrated by the innovative CeO2-SiO2 mixed oxide catalyst (CeSi2) with excellent SO2/H2O resistance in harsh working conditions. The strong Ce-O-Si interaction and abundant surface hydroxyl groups on CeSi2 provide active acid sites and inhibit SO2 adsorption, enhancing the NH3-SCR performance through an enhanced Eley-Rideal mechanism. This work offers a strategy to develop an environmentally friendly NH3-SCR catalyst with superior SO2 resistance.
ENVIRONMENTAL SCIENCE & TECHNOLOGY
(2021)
Article
Engineering, Environmental
Shaohua Xie, Zhiwei Wang, Wei Tan, Yatong Zhu, Samantha Collier, Lu Ma, Steven N. Ehrlich, Peng Xu, Yong Yan, Tao Xu, Jiguang Deng, Fudong Liu
Summary: A novel two-step wetness impregnation method was developed to fabricate a unique and highly stable CeO2/Al2O3 support, enabling Pd catalysts anchored on this support to exhibit higher activity and thermal stability in CO and hydrocarbon oxidations. This approach can be applied as a universal method to prepare stable metal oxide-alumina-based supports, with broad applications in environmental catalyst design.
ENVIRONMENTAL SCIENCE & TECHNOLOGY
(2021)
Article
Chemistry, Applied
Wei Tan, Jin Wang, Yandi Cai, Lulu Li, Shaohua Xie, Fei Gao, Fudong Liu, Lin Dong
Summary: This study proposes a new strategy of Mo doping to improve the low-temperature SCR activity of CeSi2. A Mo-Ce-Si mixed-oxide catalyst was prepared by a simple co-precipitation method. Mo doping significantly enhances the NH3-SCR activity of CeSi2 and exhibits superior N2 selectivity and resistance to SO2/H2O poisoning.
Article
Chemistry, Multidisciplinary
Wang Song, Jiawei Ji, Kai Guo, Xin Wang, Xiaoqian Wei, Yandi Cai, Wei Tan, Lulu Li, Jingfang Sun, Changjin Tang, Lin Dong
Summary: CeO2/TiO2 catalysts prepared by solid-phase impregnation showed better catalytic activity in low-temperature selective catalytic reduction of NOx with NH3. Surface changes of TiO2 were found to have a significant impact on the improved activity.
CHINESE CHEMICAL LETTERS
(2022)
Article
Engineering, Environmental
Wei Tan, Shaohua Xie, Yandi Cai, Meiyu Wang, Shuohan Yu, Ke-Bin Low, Yuejin Li, Lu Ma, Steven N. Ehrlich, Fei Gao, Lin Dong, Fudong Liu
Summary: This study explores the engineering of surface defects on CeO2 supports through ZrO2 doping to enhance the catalytic performance of Pt/CZO catalysts. Activation by H-2 reduction significantly boosts the catalytic oxidation performance of Pt/CZO catalyst and improves thermal stability, making it superior to Pt/CeO2 in vehicle emission control applications.
ENVIRONMENTAL SCIENCE & TECHNOLOGY
(2021)
Article
Engineering, Environmental
Wei Tan, Chunying Wang, Shuohan Yu, Yaobin Li, Shaohua Xie, Fei Gao, Lin Dong, Fudong Liu
Summary: The study revealed that the NH3-SCR activity of Nb2O5-CeO2 and WO3-CeO2 catalysts depends significantly on the strong interaction between the redox component (CeO2) and acidic component (Nb2O5 or WO3), as well as the presence of paired redox-acid sites. At lower temperatures (200 degrees Celsius), NH3-SCR activity is primarily influenced by the surface acidity of the catalysts, while at higher NOx conversion rates, the activity is more determined by the redox properties.
JOURNAL OF HAZARDOUS MATERIALS
(2021)
Article
Chemistry, Applied
Lulu Li, Jiawei Ji, Wei Tan, Wang Song, Xin Wang, Xiaoqian Wei, Kai Guo, Wanyu Zhang, Changjin Tang, Lin Dong
Summary: In this work, a supported catalyst consisting of FeOx and MnOx co-supported on aluminum-modified CeO2 was synthesized and applied in the low-temperature NH3-selective catalytic reduction (NH3-SCR) of NO. The study revealed that the SCR activity of the catalyst was significantly influenced by the amount of added aluminum and the appropriate Ce/Al molar ratio. The Fe-Mn/Ce1Al2 catalyst exhibited over 90% NO conversion at a temperature range of 75-250 degrees Celsius and displayed better resistance to SO2 compared to FeeMn/CeO2.
JOURNAL OF RARE EARTHS
(2022)
Article
Engineering, Environmental
Wei Tan, Shaohua Xie, Xin Wang, Chunying Wang, Yaobin Li, Thomas E. Shaw, Lu Ma, Steven N. Ehrlich, Annai Liu, Jiawei Ji, Fei Gao, Lin Dong, Fudong Liu
Summary: The study focuses on the improvement of Pt-CeO2 catalysts by designing new ceria-based supports. Through a unique T-IWI method, a Pt single site catalyst with excellent thermal stability was synthesized on a CZA-T support. The catalyst showed higher oxidation activity and Oxygen storage capacity (OSC) compared to traditional Pt catalysts on regular CeO2/Al2O3 and one-step prepared CeZrOx/Al2O3 supports. The higher Pt dispersion and stronger Pt-O-Ce interaction on the CZA-T support played a vital role in the CO oxidation performance and OSC of the catalyst.
CHEMICAL ENGINEERING JOURNAL
(2021)
Article
Chemistry, Physical
Shaohua Xie, Wei Tan, Yuejin Li, Lu Ma, Steven N. Ehrlich, Jiguang Deng, Peng Xu, Fei Gao, Lin Dong, Fudong Liu
Summary: In this study, an efficient NbCuCe oxide catalyst for reducing NOx emissions in cold-start diesel engines is reported. The catalyst exhibits higher DeNO(x) activity below 200 degrees C compared to the Cu-CHA zeolite catalyst, along with superior sulfur resistance, faster response, and lower NH3 slip. Atomically dispersed Cu species facilitate strong interaction between Cu and the Nb/Ce base catalyst, leading to improved low-temperature redox properties and NH3 adsorption/activation. The developed NbCuCe catalyst shows promising potential for efficient DeNO(x) in cold-start diesel engines and can be combined with Cu-CHA for a broader temperature range of operation.
Article
Chemistry, Multidisciplinary
Shaohua Xie, Liping Liu, Yu Lu, Chunying Wang, Sufeng Cao, Weijian Diao, Jiguang Deng, Wei Tan, Lu Ma, Steven N. Ehrlich, Yaobin Li, Yan Zhang, Kailong Ye, Hongliang Xin, Maria Flytzani-Stephanopoulos, Fudong Liu
Summary: The local coordination structure of metal sites plays a crucial role in the performance of supported metal catalysts. This study successfully fabricated Pt atomic single-layer structures with precisely controlled local coordination environment, which exhibited higher turnover frequency and improved catalytic activity in CO oxidation. This work provides new insights for achieving 100% atomic utilization efficiency and optimal intrinsic catalytic activity.
JOURNAL OF THE AMERICAN CHEMICAL SOCIETY
(2022)
Article
Chemistry, Physical
Wei Tan, Shaohua Xie, Xin Wang, Juntian Xu, Yong Yan, Kaili Ma, Yandi Cai, Kailong Ye, Fei Gao, Lin Dong, Fudong Liu
Summary: In this study, an efficient CuO catalyst supported on a CeO2-Al2O3 support (CA-T) prepared by two-step incipient wetness impregnation (T-IWI) method was successfully developed. The Cu/CA-T catalyst exhibited better catalytic performance in CO oxidation and NO reduction by CO (NO + CO reaction) as well as higher thermal stability compared to the CuO catalyst loaded on conventional CeO2-Al2O3 support (Cu/CA). The microstructure of CuO-CeO2-Al2O3 catalysts, especially the state of Cu species, was systematically investigated using various characterization techniques. The mechanisms of CO oxidation and NO + CO reactions on Cu/CA and Cu/CA-T catalysts were collaboratively revealed.
Article
Chemistry, Multidisciplinary
Qinglong Liu, Peng Yang, Wei Tan, Haowei Yu, Jiawei Ji, Cong Wu, Yandi Cai, Shaohua Xie, Fudong Liu, Song Hong, Kaili Ma, Fei Gao, Lin Dong
Summary: The size effect on nanoparticles plays a crucial role in catalysis performance. Tuning the oxygen vacancies on a metal-oxide support can help reduce the size of Pt particles, thus improving the catalysis performance of the supported catalyst. In this study, Ce-Sn solid solutions (CSO) with abundant oxygen vacancies were synthesized. After CO reduction, the catalytic CO oxidation performance of Pt/CSO was significantly better than that of Pt/CeO2. This improvement was attributed to the creation of smaller Pt clusters on CSO with more exposed active sites.
CHEMISTRY-A EUROPEAN JOURNAL
(2023)