期刊
JOURNAL OF THE AMERICAN CHEMICAL SOCIETY
卷 134, 期 51, 页码 20573-20576出版社
AMER CHEMICAL SOC
DOI: 10.1021/ja3088482
关键词
-
资金
- National Research Foundation of Korea
- Ministry of Education, Science and Technology [2012-0000908, 2011-0012141]
- Research Center Program of Institute for Basic Science
- National Research Foundation of Korea [2011-0012141] Funding Source: Korea Institute of Science & Technology Information (KISTI), National Science & Technology Information Service (NTIS)
In nature, complex and well-defined structures are constructed by the self-assembly of biomolecules. It has been shown that beta-peptide foldamers can mimic natural peptides and self-assemble into three-dimensional molecular architectures thanks to their rigid and predictable helical conformation in solution. Using shorter foldamers, which can be prepared more easily than longer ones, to form such architectures is highly desirable, but shorter foldamers have been overlooked due to the seemingly inferior number of intramolecular hydrogen bonds to stabilize a folded state in solution. Here we report that a beta-peptide tetramer, although it lacks full helical propensity in solution, does self-assemble to form well-defined microtubes with rectangular cross-section by evaporation-induced self-assembly.
作者
我是这篇论文的作者
点击您的名字以认领此论文并将其添加到您的个人资料中。
推荐
暂无数据