Article
Biochemical Research Methods
Magali Tournus, Miguel Escobedo, Wei-Feng Xue, Marie Doumic, Philip K. Maini, Mark Alber, Philip K. Maini, Mark Alber, Philip K. Maini, Mark Alber
Summary: The study discovered mathematical formulae to extract fibril division characteristics from experimental data and discussed the impact of small errors in measurements on division rate. It also suggested new experimental designs to improve estimates of division patterns.
PLOS COMPUTATIONAL BIOLOGY
(2021)
Review
Chemistry, Applied
J. H. Markna, Prashant K. Rathod
Summary: This review article provides a comprehensive overview of the efficiency of quantum dot sensitized solar cells (QDSCs) based on dye-synthesized solar cells and nanotechnology, and discusses their status under the influence of photoanode and quantum dot sensitizers.
Article
Chemistry, Physical
Daniel T. W. Toolan, Michael P. P. Weir, Shuangqing Wang, Simon A. A. Dowland, Zhilong Zhang, James Xiao, Jonathan Rawle, Neil Greenham, Richard H. H. Friend, Akshay Rao, Richard A. L. Jones, Anthony J. J. Ryan
Summary: Organic-inorganic nanocomposite films formed from blends of small-molecule organic semiconductors and colloidal quantum dots are promising for solar energy harvesting devices. Understanding and controlling the self-assembly of these films is crucial for device optimization, especially for large-scale manufacturing techniques.
NANOSCALE HORIZONS
(2023)
Article
Multidisciplinary Sciences
Pratibha Kumari, Dhiman Ghosh, Agathe Vanas, Yanick Fleischmann, Thomas Wiegand, Gunnar Jeschke, Roland Riek, Cedric Eichmann
Summary: This study investigated the interaction between monomeric alpha-Syn and its fibrillar form using NMR and electron paramagnetic resonance spectroscopy, revealing that intermolecular interactions reduce intramolecular contacts in monomeric alpha-Syn, leading to further unfolding of its intrinsically disordered states and critically contributing to the aggregation kinetics of alpha-Syn during secondary nucleation.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
(2021)
Article
Food Science & Technology
Daniel Golodnizky, Maya Davidovich-Pinhas
Summary: The transition from an isotropic liquid state to an organized crystalline state of triacylglycerols is important in designing lipid-based materials and food products. The research suggests that the conversion from the tuning-fork (Tf) conformation to other conformations is the limiting factor during nucleation, while the conversion to the Tf conformation from other conformations is the limiting factor during crystal growth.
INNOVATIVE FOOD SCIENCE & EMERGING TECHNOLOGIES
(2022)
Article
Multidisciplinary Sciences
Satyendra Nath Gupta, Ora Bitton, Tomas Neuman, Ruben Esteban, Lev Chuntonov, Javier Aizpurua, Gilad Haran
Summary: Plasmonic cavities can confine electromagnetic radiation to deep sub-wavelength regimes, allowing for strong coupling phenomena with individual quantum emitters. By studying scattering spectra and using interferometry, researchers observed Rabi splitting and non-classical emission in devices with semiconductor quantum dots, revealing complex interactions between bright and dark states. Model simulations based on an extended Jaynes-Cummings Hamiltonian explained the experimental findings, highlighting the potential of controlling quantum state dynamics through the coupling of quantum emitters to plasmonic cavities.
NATURE COMMUNICATIONS
(2021)
Article
Medicine, Research & Experimental
Jackson L. Amaral, Pedro F. N. Souza, Jose T. A. Oliveira, Valder N. Freire, Daniele O. B. Sousa
Summary: The study analyzed the action mechanisms of the synthetic peptide Mo-CBP3-PepIII against Candida albicans, showing strong interaction with EXG at the active site, insertion into the yeast membrane, induction of cracks and scars in the cell wall, and pore formation on the Candida membrane. Mo-CBP3-PepIII has strong potential as a new drug with a broad spectrum of action due to its different mode of action compared to conventional drugs.
Article
Chemistry, Physical
Xichen Huang, Yanyun Sun, Xiaoxi Tan, Chaobo Zhang, Yu Huang, WenQiang Liao, Fusheng Liu
Summary: In this study, a kinetic model is developed that combines classical nucleation theory with Mie theory, reproducing the experimental phenomenon of water rapid freezing. The process of ice formation and the decrease in transmissivity during freezing are revealed. The change in transparency may be caused by ice/vacuum interface scattering, and an approximate formula between nucleation rate and sample transparency is given.
PHYSICAL CHEMISTRY CHEMICAL PHYSICS
(2023)
Editorial Material
Neurosciences
Michael Fine, Xiaochun Li
Summary: TRPA1 is identified as a promising target for novel treatments of chronic pain. The study introduces a new non-covalent TRPA1-biased agonist, GNE551, which reveals a unique binding pocket and activation properties that lay the groundwork for new avenues in chronic pain treatment.
Article
Thermodynamics
Jun Zhang, Zili Wang, Liwen Li, Youguo Yan, Jiafang Xu, Jie Zhong
Summary: This study investigates the kinetic roles of methanol in hydrate nucleation using molecular dynamics simulation. The results show that the addition of methanol can inhibit hydrate nucleation, and this inhibition effect is related to the H-bond formation ability between methanol and water molecules.
Article
Multidisciplinary Sciences
Emmanuel W. Smith, Simon Lattmann, Zhehui Barry Liu, Bilal Ahsan, Daniela Rhodes
Summary: This study reports the structures of POT1 bound by TPP1, revealing the flexibility of the OB1 and OB2 folds in DNA binding. It is found that POT1 has strong DNA binding capacity and can adapt to different binding sites. These findings suggest that the structural flexibility of POT1 enhances its binding to telomeric repeats and increases telomere protection.
Article
Chemistry, Physical
Sabyasachi Pramanik, Mihir Manna, Biswajit Hudait, Shilaj Roy, Satyapriya Bhandari
Summary: A complexation reaction between Zn2+ ions and a non-emitting copper quinolate complex led to the formation of a greenish blue-emitting surface zinc quinolate complex, contributing to the production of photostable bright white light by the quantum dot complex (QDC). The reaction rate was observed to be first order with respect to CuQ(2), with a complexation constant for the formation of ZnQ(2) estimated to be 8.3 x 10(5) M-1.
PHYSICAL CHEMISTRY CHEMICAL PHYSICS
(2021)
Article
Chemistry, Multidisciplinary
Daniel T. W. Toolan, Michael P. Weir, Jesse Allardice, Joel A. Smith, Simon A. Dowland, Jurjen Winkel, James Xiao, Zhilong Zhang, Victor Gray, Adam L. Washington, Anthony J. Petty, John E. Anthony, Neil C. Greenham, Richard H. Friend, Akshay Rao, Richard A. L. Jones, Anthony J. Ryan
Summary: Controlling the dispersibility of crystalline inorganic quantum dots within organic-QD nanocomposite films is crucial for a wide range of optoelectronic devices. Using appropriate organic ligands on the quantum dots can help compatibilize them with the organic host, both electronically and structurally. The surface chemistry of quantum dot ligands has a pronounced effect on the self-assembly of nanocomposite films.
ADVANCED FUNCTIONAL MATERIALS
(2022)
Article
Chemistry, Multidisciplinary
Nikita Orekhov, Nikolay Kondratyuk, Mikhail Logunov, Alexandra Timralieva, Vladimir Shilovskikh, Ekaterina Skorb
Summary: This study provides molecular insights into the self-assembly of melamine cyanurate in aqueous solution and identifies mechanisms of aggregation. The research suggests that the formation of small M-CA complexes is mainly stabilized through aromatic p-p stacking rather than hydrogen bond formation. It also demonstrates that changing the concentration ratio of M to CA leads to a variation in the structure of critical nuclei, indicating a potential for the programmable design of functional supramolecular materials.
CRYSTAL GROWTH & DESIGN
(2021)
Article
Chemistry, Multidisciplinary
Sarthak Nag, Yoko Tomo, Koji Takahashi, Masamichi Kohno
Summary: This study investigates the merging process of surface nanobubbles using liquid-phase electron microscopy, revealing that the merging of stable nanobubbles is initiated by gradual localized changes in the physical properties of the region between adjoining nanobubble boundaries. The analysis of gas exchange mechanisms during the merging process enhances understanding of nanobubble behavior and dynamics, leading to potential new applications in various fields.
Article
Physics, Applied
Zhentao Hou, Trevor M. Tumiel, Todd D. Krauss
Summary: Single-molecule microscopy was used to observe photoluminescence brightening of individual sodium-dodecyl-sulfate-wrapped single-walled carbon nanotubes upon the addition of dithiothreitol. The photoluminescence enhancement varied for each nanotube, and longer nanotubes showed a uniform brightening phenomenon along their length.
JOURNAL OF APPLIED PHYSICS
(2021)
Article
Chemistry, Physical
Rebeckah Burke, Kara L. Bren, Todd D. Krauss
Summary: This article focuses on the implementation of semiconductor NCs for photochemical fuel formation, discussing different system designs and relevant reactions toward solar fuel targets. It also highlights the versatile roles of NCs in light-driven chemical reactions and provides perspectives on the future of the field.
JOURNAL OF CHEMICAL PHYSICS
(2021)
Article
Chemistry, Multidisciplinary
Sean W. O'Neill, Todd D. Krauss
Summary: This study focuses on understanding the fundamental chemical mechanisms involved in the formation of SnTe nanocrystals and identifies key reactive species that initiate the formation and growth. This knowledge is crucial for the production of high-quality SnTe nanocrystals.
JOURNAL OF THE AMERICAN CHEMICAL SOCIETY
(2022)
Article
Chemistry, Multidisciplinary
Jonas K. Widness, Daniel G. Enny, Kaelyn S. McFarlane-Connelly, Mahilet T. Miedenbauer, Todd D. Krauss, Daniel J. Weix
Summary: This paper reports the use of CdS nanocrystal quantum dots as strong photoreductants for efficient photoreductive cleavage of aryl chlorides and phosphate esters. The conditions described in this study also enable other challenging reductions and achieve high turnover numbers. The stability of the CdS quantum dots under these conditions makes them a promising catalyst for various reduction reactions.
JOURNAL OF THE AMERICAN CHEMICAL SOCIETY
(2022)
Article
Chemistry, Physical
Wenxiang Hu, Ignacio Gustin, Todd D. Krauss, Ignacio Franco
Summary: This article demonstrates how quantum light in optical cavities can be used to protect the quantum coherence of molecular chromophores and generate quantum superposition states with tunable coherence time scales. The study shows that by implementing these tunable coherence enhancements in lossy cavities, the quantum coherence lifetime in molecules can be increased.
JOURNAL OF PHYSICAL CHEMISTRY LETTERS
(2022)
Article
Chemistry, Physical
Erin E. Christensen, Mitesh Amin, Trevor M. Tumiel, Todd D. Krauss
Summary: This study investigates the electrostatic interactions of single-walled carbon nanotubes using electrostatic force microscopy. The results show that surfactant coverage on long nanotubes leads to nonuniform spatial charge distributions and the potential well depth can be estimated by charge densities, suggesting the localization of excitons.
JOURNAL OF PHYSICAL CHEMISTRY LETTERS
(2022)
Article
Chemistry, Physical
Braden M. Weight, Todd D. Krauss, Pengfei Huo
Summary: Coupling molecules to the quantized radiation field inside an optical cavity creates new photon-matter hybrid states called polariton states. We investigate molecular polaritons using ab initio simulations by combining electronic structure theory with quantum electrodynamics (QED). This parametrized QED approach provides exact molecule-cavity interactions, limited by approximations made in the electronic structure. Our demonstrated accuracy and selected applications in light-harvesting and light-emitting materials suggest that this framework can be a powerful tool for simulating exciton polaritons in molecule-cavity hybrid systems.
JOURNAL OF PHYSICAL CHEMISTRY LETTERS
(2023)
Article
Multidisciplinary Sciences
Emily H. Edwards, Jana Jelusic, Ryan M. Kosko, Kevin P. McClelland, Soraya S. Ngarnim, Wesley Chiang, Sanela Lampa-Pastirk, Todd D. Krauss, Kara L. Bren
Summary: A new approach to constructing a living bio-nano system for hydrogen production using semiconductor nanoparticles and electrogenic bacteria is demonstrated.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
(2023)
Article
Chemistry, Physical
Julianna M. Mouat, Jonas K. Widness, Daniel G. Enny, Mahilet T. Meidenbauer, Farwa Awan, Todd D. Krauss, Daniel J. Weix
Summary: This study demonstrates that 5.7 nm CdS quantum dots (QDs) are efficient photocatalysts for photoredox-promoted cross-electrophile coupling with a high turnover number (up to 40,000). NMR studies reveal that triethanolamine-capped QDs serve as the active catalyst and can displace native ligands on the QD surface, highlighting the significance of surface chemistry in catalytic performance.
Article
Nanoscience & Nanotechnology
Abigail Freyer, Trevor M. Tumiel, Michelle Smeaton, Benjamin H. Savitzky, Lena F. Kourkoutis, Todd D. Krauss
Summary: Cation exchange is commonly used for doping nanocrystals, but the relationships between the exchange process, the doped products, and the resulting photophysics are not well understood. Single molecule investigations of Ag+ doping on CdSe nanocrystals reveal the presence of multiple species within a single sample, suggesting that the differences in optical properties are due to the contributions of each species. The heterogeneity of the doped samples highlights the challenges in controlling the cation exchange method for producing homogeneous samples.
ACS NANOSCIENCE AU
(2023)
Article
Chemistry, Physical
M. Elious Mondal, Eric R. Koessler, Justin Provazza, A. Nickolas Vamivakas, Steven T. Cundiff, Todd D. Krauss, Pengfei Huo
Summary: We have developed an accurate and numerically efficient method for simulating the non-linear spectroscopy of exciton-polariton systems. By investigating the influence of light-matter coupling strength and cavity loss rate on the optical response, we have confirmed the polaron decoupling effect and demonstrated the prolongation of polariton coherence time.
JOURNAL OF CHEMICAL PHYSICS
(2023)
Article
Nanoscience & Nanotechnology
Wesley Chiang, Angela Stout, Francine Yanchik-Slade, Herman Li, Niccolo Terrando, Bradley L. L. Nilsson, Harris A. A. Gelbard, Todd D. D. Krauss
Summary: Despite limited evidence for SARS-CoV-2 infection in the central nervous system, cognitive impairment is a common complication in recovered COVID-19 patients. In this study, nanocrystal quantum dot micelles decorated with spike protein were used to investigate neurological damage caused by SARS-CoV-2. The findings provide evidence of an inflammatory response in brain cells without direct exposure to SARS-CoV-2-like nanoparticles and suggest potential neuroprotective strategies.
ACS APPLIED NANO MATERIALS
(2023)
Article
Chemistry, Multidisciplinary
Nicole M. B. Cogan, Kevin P. Mcclelland, Chari Y. M. Peter, Chayan Carmenate Rodriguez, Alex A. Fertig, Mitesh Amin, William W. Brennessel, Todd D. Krauss, Ellen M. Matson
Summary: A limitation in the implementation of cadmium chalcogenide quantum dots (QDs) in charge transfer systems is the efficient removal of photogenerated holes. This study shows that incorporating oxygen vacancies into polyoxovanadate-alkoxide clusters can improve hole transfer kinetics and facilitate QD-hole acceptor association through reversible complexation.
Article
Biochemistry & Molecular Biology
Elizabeth R. Piedmont, Erin E. Christensen, Todd D. Krauss, Benjamin E. Partridge
Summary: This study reports a series of amphiphilic dendrons that can assemble into sphere-like particles in aqueous solutions and inhibit the aggregation of Aβ16-22 protein. The solubility of these dendrons and their assemblies can be tuned by varying the relative sizes of their hydrophilic and hydrophobic regions. These dendrons mimic the activity of holdase chaperones by stabilizing Aβ16-22 peptide with respect to aggregation at sub-stoichiometric concentrations. These findings highlight the potential of these amphiphilic molecules as a novel approach to artificial chaperones.
RSC CHEMICAL BIOLOGY
(2023)
Proceedings Paper
Engineering, Biomedical
Wesley Chiang, Jennifer Urban, Angela Litzburg, Bradley Nilsson, Harris Gelbard, Todd Krauss
Summary: In this study, quantum dots were encapsulated in polymeric phospholipid micelles conjugated to multiple ligands of SARS-CoV-2 spike protein, forming fluorescent biomimetic nanoparticles. The average number of spike proteins conjugated per COVID-QD was estimated to be seven. By using these COVID-QD constructs in an in-vitro model system for the neurovascular unit, the study investigated the potential modulation of NVU and its association with COVID-19 neuropathophysiology.
COLLOIDAL NANOPARTICLES FOR BIOMEDICAL APPLICATIONS XVII
(2022)
