Review
Chemistry, Analytical
Mariola Brycht, Lukasz Poltorak, Simona Baluchova, Karolina Sipa, Paulina Borgul, Konrad Rudnicki, Slawomira Skrzypek
Summary: This review comprehensively describes the progress in electrochemistry of ANAs over the last four decades, focusing on the development of electrochemical sensing protocols and achievements in studying the interactions of ANAs with DNA, carcinogenic cells, biomimetic membranes, peptides, and enzymes.
CRITICAL REVIEWS IN ANALYTICAL CHEMISTRY
(2022)
Review
Food Science & Technology
Duoduo Zhang, Xingtao Zhou, Wengan Zhou, Steve W. Cui, Shaoping Nie
Summary: This paper summarizes the complex mechanisms through which dietary nutrients regulate intestinal homeostasis, and introduces the application and advantages of intestinal organoid (IO) in investigating the interaction between nutrients and intestinal balance. It also highlights the importance of using IOs to study the mechanisms of macronutrients and micronutrients on intestinal homeostasis, as well as their potential in precision nutrition research.
FOOD RESEARCH INTERNATIONAL
(2023)
Review
Cell Biology
Oksana Shevchuk, Svitlana Palii, Anastasiia Pak, Nuria Chantada, Nuria Seoane, Mykhaylo Korda, Manuel Campos-Toimil, Ezequiel alvarez
Summary: COVID-19 causes various vascular and blood-related reactions. Endothelial cells play a remarkable role in the acute response and may remain important beyond the acute phase. Research is needed to determine the vascular consequences of COVID-19 and the potential long-term effects on the cardiovascular system. Vessel-on-a-chip technology shows potential in studying COVID-19 pathophysiology and could be used for personalized follow-up of the disease and research of new drugs.
Article
Chemistry, Applied
Stephane Loridant
Summary: This paper reviews the various opportunities offered by Raman spectroscopy for advanced characterization of ceria-based catalysts, including spectral modifications induced by nanocrystallinity, defects, doping, reduction, identification of supported molecular species, isolated atoms, nanoclusters, surface modes, hydroxyl groups, and reaction intermediates. In situ/operando studies for environmental catalysis are also summarized, highlighting Raman spectroscopy as a powerful tool for characterizing ceria-based catalysts.
Review
Biochemical Research Methods
Jennifer Noro, Artur Cavaco-Paulo, Carla Silva
Summary: The demand for diverse and eco-friendly production procedures has led to advancements in the field of enzymes, with lipases being excellent catalysts. Lipases have a wide range of applications, and their activity can be enhanced through structural and chemical modifications. This review provides practical insights into the strategies developed in recent years for lipase modification and how it impacts their activity, stability, and biotechnological applications.
BIOTECHNOLOGY JOURNAL
(2022)
Article
Chemistry, Applied
Lucile Lecas, Vincent Dugas, Claire Demesmay
Summary: Affinity chromatography, often overlooked in receptor/ligand studies, offers new perspectives with its simplicity and ability to provide diverse information. Different immobilization strategies have been developed to encompass a wide range of applications, from ligand-ranking to fragment screening and identification of active components from natural extracts.
SEPARATION AND PURIFICATION REVIEWS
(2021)
Review
Chemistry, Multidisciplinary
Tianyi Chen, Jialin Xin, Shwu Jen Chang, Ching-Jung Chen, Jen-Tsai Liu
Summary: Interface phenomena are caused by various physical and chemical processes at phase interfaces and have applications in many fields. Traditional detection equipment is limited in observing interface phenomena, but surface plasmon resonance (SPR) combined technology is a powerful tool for investigating these phenomena and providing valuable information. In the future, SPR combined technology will develop towards signal enhancement, light source coupling mode, and sensor chip design, enabling real-time in situ detection of interface phenomena.
ADVANCED MATERIALS INTERFACES
(2023)
Article
Polymer Science
Mustapha El Hariri El Nokab, Mohamed H. Habib, Yasser A. Alassmy, Marwan M. Abduljawad, Khalid M. Alshamrani, Khaled O. Sebakhy
Summary: Solid state nuclear magnetic resonance (ssNMR) is a powerful tool for studying the chemical structure and dynamics of various materials. It is particularly advanced in the structural analysis of cellulose-based materials. However, its capabilities are often underestimated due to the lack of pulse sequences and time-consuming experiments.
Article
Chemistry, Physical
Alexandru Vincentiu Florian Neculae, Gerard Audran, Sofiane Bourdillon, Gabriela Ionita, Jean Patrick Joly, Sylvain R. A. Marque, Iulia Matei, Sorin Mocanu
Summary: The isotropic hyperfine coupling constants of p-phosphorylated nitroxides corresponding to nitrogen and phosphorous atoms are sensitive to polarity and local interactions, leading to changes in molecular conformation. The study demonstrates different solvent effects and interactions of these nitroxides with cyclodextrins of various cavity sizes. The binding constants show high sensitivity to cyclodextrin concentration and the association process can be reversible. This research highlights the potential of using p-phosphorylated nitroxides as analytical markers for discriminating between different cyclodextrin solutions based on EPR spectra patterns.
JOURNAL OF MOLECULAR LIQUIDS
(2022)
Review
Chemistry, Physical
Thi Ngoc Lam Tran, Alessandro Chiasera, Anna Lukowiak, Maurizio Ferrari
Summary: The unique spectroscopic properties of Eu3+ ion make it a powerful tool in various high-tech application areas, such as biology, structural engineering, environmental monitoring systems, and quantum technology. By utilizing the photoluminescent properties of Eu3+ ions, researchers can understand complex dynamical processes and develop materials with specific characteristics. Eu3+ optical spectroscopy is also utilized in probing local structures, studying dynamical processes, and developing rare-earth-based platforms for quantum technologies.
Article
Chemistry, Physical
Katrin Zoeller, Anna Karlegger, Martyna Truszkowska, Daniel Stengel, Andreas Bernkop-Schnuerch
Summary: This study investigates the cellular uptake of hydrophobic complexes via nanocarriers using hydrophobic ion pairs (HIPs) formed between two fluorescent components. The results show that HIPs increase the lipophilicity of the model drugs and incorporating HIPs into nanoemulsions (NE) further enhances cellular uptake. HIPs serve as a powerful tool to visualize the cellular distribution of hydrophobic complexes and study their cellular uptake.
JOURNAL OF COLLOID AND INTERFACE SCIENCE
(2024)
Article
Toxicology
Andrea Gerdemann, Matthias Behrens, Melanie Esselen, Hans-Ulrich Humpf
Summary: Mycotoxins are secondary fungal metabolites that exhibit toxic effects in low concentrations. Metabolic profiling is a powerful tool for evaluating the toxicity of xenobiotics such as mycotoxins.
ARCHIVES OF TOXICOLOGY
(2022)
Article
Chemistry, Physical
Josipa Sarjanovic, Martina Stojic, Mirta Rubcic, Luka Pavic, Jana Pisk
Summary: Molybdenum coordination complexes with biological and pharmacological potential and good catalytic performance were synthesized using a hydrazone Schiff-base tetradentate ligand. The structures of the ligands and complexes were determined by spectroscopic methods and X-ray diffraction. The electrical properties of the complexes were examined using impedance spectroscopy.
Review
Chemistry, Medicinal
Francesca Ruggieri, Nina Compagne, Kevin Antraygues, Maxime Eveque, Marion Flipo, Nicolas Willand
Summary: Antimicrobial resistance (AMR) is a major public health issue causing 5 million deaths per year. To combat this problem, new antibiotics with novel targets or modes of action are needed. Promising compounds such as gepotidacin, zoliflodacin, ibezapolstat, MGB-BP-3, CRS-3123, afabicin, TXA-709, and recently approved lefamulin have shown potential in clinical trials. This review provides information on the chemical synthesis, mode of action, structure-activity relationships, in vitro and in vivo activities, and clinical data of these eight small molecules.
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY
(2023)
Article
Chemistry, Multidisciplinary
Yu Fukunaga, Rintaro Ogawa, Amane Homma, Tetsuo Okada
Summary: Thin layer chromatography (TLC) is used to confirm chemical synthesis by identifying spot retention factors. Coupling TLC with surface-enhanced Raman spectroscopy (SERS) overcomes challenges and freezing eliminates interference, enhancing TLC-SERS performance. TLC-freeze SERS can monitor reactions, identify similar products, detect compounds with high sensitivity, and provide reliable reaction time determination.
CHEMISTRY-A EUROPEAN JOURNAL
(2023)
