A Network-Based Target Overlap Score for Characterizing Drug Combinations: High Correlation with Cancer Clinical Trial Results

JBioWH: an open-source Java framework for bioinformatics data integration

(2013) R. Vera et al.   Database-The Journal of Biological Databases and Curation

The drug cocktail network

(2012) Ke-Jia Xu et al.   BMC Systems Biology

INDI: a computational framework for inferring drug interactions and their associated recommendations

(2012) Assaf Gottlieb et al.   Molecular Systems Biology

STRING v9.1: protein-protein interaction networks, with increased coverage and integration

(2012) Andrea Franceschini et al.   NUCLEIC ACIDS RESEARCH

An enhanced Petri-net model to predict synergistic effects of pairwise drug combinations from gene microarray data

(2011) G. Jin et al.   BIOINFORMATICS

Network target for screening synergistic drug combinations with application to traditional Chinese medicine

(2011) Shao Li et al.   BMC Systems Biology

Four-Year Follow-Up of Trastuzumab Plus Adjuvant Chemotherapy for Operable Human Epidermal Growth Factor Receptor 2–Positive Breast Cancer: Joint Analysis of Data From NCCTG N9831 and NSABP B-31

(2011) Edith A. Perez et al.   JOURNAL OF CLINICAL ONCOLOGY

Systematic exploration of synergistic drug pairs

(2011) M. Cokol et al.   Molecular Systems Biology

Therapeutic target database update 2012: a resource for facilitating target-oriented drug discovery

(2011) F. Zhu et al.   NUCLEIC ACIDS RESEARCH

STITCH 3: zooming in on protein-chemical interactions

(2011) M. Kuhn et al.   NUCLEIC ACIDS RESEARCH

Prediction of Drug Combinations by Integrating Molecular and Pharmacological Data

(2011) Xing-Ming Zhao et al.   PLoS Computational Biology

Candidate gene prioritization by network analysis of differential expression using machine learning approaches

(2010) Daniela Nitsch et al.   BMC BIOINFORMATICS

A systems biology approach to identify effective cocktail drugs

(2010) Zikai Wu et al.   BMC Systems Biology

Network medicine: a network-based approach to human disease

(2010) Albert-László Barabási et al.   NATURE REVIEWS GENETICS

DrugBank 3.0: a comprehensive resource for 'Omics' research on drugs

(2010) C. Knox et al.   NUCLEIC ACIDS RESEARCH

Pre-Clinical Drug Prioritization via Prognosis-Guided Genetic Interaction Networks

(2010) Jianghui Xiong et al.   PLoS One

Associating Genes and Protein Complexes with Disease via Network Propagation

(2010) Oron Vanunu et al.   PLoS Computational Biology

DCDB: Drug combination database

(2009) Y. Liu et al.   BIOINFORMATICS

Disease candidate gene identification and prioritization using protein interaction networks

(2009) Jing Chen et al.   BMC BIOINFORMATICS

Prognosis of Women With Metastatic Breast Cancer byHER2Status and Trastuzumab Treatment: An Institutional-Based Review

(2009) Shaheenah Dawood et al.   JOURNAL OF CLINICAL ONCOLOGY

Synergistic drug combinations tend to improve therapeutically relevant selectivity

(2009) Joseph Lehár et al.   NATURE BIOTECHNOLOGY

Semantic Similarity in Biomedical Ontologies

(2009) Catia Pesquita et al.   PLoS Computational Biology

ROC analysis: applications to the classification of biological sequences and 3D structures

(2008) P. Sonego et al.   BRIEFINGS IN BIOINFORMATICS

Cinfony – combining Open Source cheminformatics toolkits behind a common interface

(2008) Noel M O'Boyle et al.   Chemistry Central Journal

Finding multiple target optimal intervention in disease-related molecular network

(2008) Kun Yang et al.   Molecular Systems Biology

Network pharmacology: the next paradigm in drug discovery

(2008) Andrew L Hopkins   Nature Chemical Biology

Closed-loop control of cellular functions using combinatory drugs guided by a stochastic search algorithm

(2008) Pak Kin Wong et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Search Algorithms as a Framework for the Optimization of Drug Combinations

(2008) Diego Calzolari et al.   PLoS Computational Biology

Balanced ROC analysis (BAROC) protocol for the evaluation of protein similarities

(2007) Róbert Busa-Fekete et al.