期刊
JOURNAL OF THE AMERICAN CHEMICAL SOCIETY
卷 130, 期 49, 页码 16502-+出版社
AMER CHEMICAL SOC
DOI: 10.1021/ja807696e
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资金
- National Science Foundation
- National Institutes of Health [NIH-13598]
The Ruthenium catalyzed, atom-economical domino redox isomerization/cyclization of tethered aminopropargyl alcohols is reported. This process displays a broad scope and functional group tolerance, Furthermore, it presents a novel retrosynthetic disconnection linking simple and easily available, linear propargyl alcohols with added-value nitrogen heterocycles in a single catalytic step. [GRAPHICS]
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