A Randomized Controlled Trial on the Effect of Tapentadol and Morphine on Conditioned Pain Modulation in Healthy Volunteers

Tapentadol potentiates descending pain inhibition in chronic pain patients with diabetic polyneuropathy

(2014) M. Niesters et al.   BRITISH JOURNAL OF ANAESTHESIA

Recommendations on practice of conditioned pain modulation (CPM) testing

(2014) D. Yarnitsky et al.   EUROPEAN JOURNAL OF PAIN

Distinct brain mechanisms support spatial vs temporal filtering of nociceptive information

(2014) Hadas Nahman-Averbuch et al.   PAIN

Influence of ketamine and morphine on descending pain modulation in chronic pain patients: a randomized placebo-controlled cross-over proof-of-concept study

(2013) M. Niesters et al.   BRITISH JOURNAL OF ANAESTHESIA

Oxycodone alters temporal summation but not conditioned pain modulation: Preclinical findings and possible relations to mechanisms of opioid analgesia

(2013) Erica Suzan et al.   PAIN

Pain modulation profile and pain therapy: Between pro- and antinociception

(2013) David Yarnitsky et al.   PAIN

Effectiveness and safety of tapentadol prolonged release with tapentadol immediate release on-demand for the management of severe, chronic osteoarthritis-related knee pain: results of an open-label, phase 3b study

(2012) Ilona Steigerwald et al.   Journal of Pain Research

Offset Analgesia in Neuropathic Pain Patients and Effect of Treatment with Morphine and Ketamine

(2011) Marieke Niesters et al.   ANESTHESIOLOGY

A Double-blind, Placebo-controlled Study on the Effect of Buprenorphine and Fentanyl on Descending Pain Modulation

(2011) Lars Arendt-Nielsen et al.   CLINICAL JOURNAL OF PAIN

Pronociceptive Pain Modulation in Patients with Painful Chemotherapy-Induced Polyneuropathy

(2011) Hadas Nahman-Averbuch et al.   JOURNAL OF PAIN AND SYMPTOM MANAGEMENT

Synergistic Interaction between the Two Mechanisms of Action of Tapentadol in Analgesia

(2011) W. Schroder et al.   JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS

The antinociceptive and antihyperalgesic effect of tapentadol is partially retained in OPRM1 (μ-opioid receptor) knockout mice

(2011) Babette Kögel et al.   NEUROSCIENCE LETTERS

Effect of ketamine on endogenous pain modulation in healthy volunteers

(2011) Marieke Niesters et al.   PAIN

Treating pain with pain: Supraspinal mechanisms of endogenous analgesia elicited by heterotopic noxious conditioning stimulation

(2011) Christian Sprenger et al.   PAIN

Engagement of descending inhibition from the rostral ventromedial medulla protects against chronic neuropathic pain

(2011) Milena De Felice et al.   PAIN

Descending Inhibitory Pain Modulation Is Impaired in Patients With Chronic Pancreatitis

(2010) Søren Schou Olesen et al.   Clinical Gastroenterology and Hepatology

Recommendations on terminology and practice of psychophysical DNIC testing

(2010) David Yarnitsky et al.   EUROPEAN JOURNAL OF PAIN

Central modulation of pain

(2010) Michael H. Ossipov et al.   JOURNAL OF CLINICAL INVESTIGATION

Perspective on Diffuse Noxious Inhibitory Controls as a Model of Endogenous Pain Modulation in Clinical Pain Syndromes

(2010) Gerrit van Wijk et al.   JOURNAL OF PAIN

An Experimental Paradigm for the Prediction of Post-Operative Pain (PPOP)

(2010) Ruth Landau et al.   Jove-Journal of Visualized Experiments

Differential endogenous pain modulation in complex-regional pain syndrome

(2009) F. Seifert et al.   BRAIN

Deficiency in endogenous modulation of prolonged heat pain in patients with Irritable Bowel Syndrome and Temporomandibular Disorder

(2009) Christopher D. King et al.   PAIN

The methodology of experimentally induced diffuse noxious inhibitory control (DNIC)-like effect in humans

(2009) Dorit Pud et al.   PAIN

Single Dose Analgesic Efficacy of Tapentadol in Postsurgical Dental Pain: The Results of a Randomized, Double-Blind, Placebo-Controlled Study

(2008) Regina Kleinert et al.   ANESTHESIA AND ANALGESIA

Prediction of chronic post-operative pain: Pre-operative DNIC testing identifies patients at risk

(2008) David Yarnitsky et al.   PAIN