Article
Neurosciences
Zi-Yue Liu, Fei-Fei Zhai, Fei Han, Ming-Li Li, Lixin Zhou, Jun Ni, Ming Yao, Shu-Yang Zhang, Li-Ying Cui, Zheng-Yu Jin, Yi-Cheng Zhu
Summary: The study aims to investigate the association between white matter microstructure and structural network changes with different cognitive domains. The findings suggest that white matter damage and connectivity issues are closely related to cognitive impairment in the elderly population, with the anterior brain predominantly involved in executive dysfunction and the midline and right temporal brain primarily involved in verbal memory loss.
JOURNAL OF ALZHEIMERS DISEASE
(2022)
Article
Oncology
Holly A. Aleksonis, Lisa C. Krishnamurthy, Tricia Z. King
Summary: High white matter hyperintensity (WMH) burden is consistently associated with decreases in cognitive performance, especially processing speed, in several clinical populations. This study found that survivors of childhood cerebellar tumor, especially those treated with chemoradiation therapy, showed higher total WMH volumes and slower processing speed. Multivariate brain-behavior relationships revealed that periventricular WMHs were significantly associated with slower processing speed performance.
JOURNAL OF NEURO-ONCOLOGY
(2021)
Article
Endocrinology & Metabolism
Ruiting Zhang, Peiyu Huang, Yeerfan Jiaerken, Shuyue Wang, Hui Hong, Xiao Luo, Xiaopei Xu, Xinfeng Yu, Kaicheng Li, Qingze Zeng, Xiao Wu, Min Lou, Minming Zhang
Summary: A study revealed that in CSVD patients, disrupted DMVs cause an increase in interstitial fluid, leading to white matter damage. This link is independent of arterial perfusion variations and warrants further investigation.
JOURNAL OF CEREBRAL BLOOD FLOW AND METABOLISM
(2021)
Article
Neuroimaging
Annerine Roos, Catherine J. Wedderburn, Jean-Paul Fouche, Shantanu H. Joshi, Katherine L. Narr, Roger P. Woods, Heather J. Zar, Dan J. Stein, Kirsten A. Donald
Summary: Prenatal exposure to maternal depression increases the risk of emotional and behavioral disorders in children. This study investigates the effects of prenatal depression on white matter microstructural integrity in infants and at 2-3 years old, as well as associated neurodevelopment. The findings suggest that prenatal exposure to depression may lead to alterations in white matter integrity and impact cognitive development in early childhood.
BRAIN IMAGING AND BEHAVIOR
(2022)
Article
Clinical Neurology
Aimi Nadhiah Abdullah, Asma Hayati Ahmad, Rahimah Zakaria, Sofina Tamam, Aini Ismafairus Abd Hamid, Wen Jia Chai, Hazim Omar, Muhammad Riddha Abdul Rahman, Diana Noma Fitzrol, Zamzuri Idris, Abdul Rahman Izaini Ghani, Wan Nor Azlen Wan Mohamad, Faiz Mustafar, Muhammad Hafiz Hanafi, Mohamed Faruque Reza, Hafidah Umar, Mohd Faizal Mohd Zulkifly, Song Yee Ang, Zaitun Zakaria, Kamarul Imran Musa, Azizah Othman, Zunaina Embong, Nur Asma Sapiai, Regunath Kandasamy, Haidi Ibrahim, Mohd Zaid Abdullah, Kannapha Amaruchkul, Pedro Antonio Valdes-Sosa, Maria Luisa Bringas Vega, Bharat Biswal, Jitkomut Songsiri, Hamwira Sakti Yaacob, Putra Sumari, Nor Azila Noh, Azlinda Azman, Paramjit Singh Jamir Singh, Jafri Malin Abdullah
Summary: This study examines the state of white matter connectivity in patients with non-severe TBI during the subacute phase and its relationship with neuropsychological scores.
FRONTIERS IN NEUROLOGY
(2022)
Article
Clinical Neurology
Rebecca Kerestes, Hannah Cummins, Nellie Georgiou-Karistianis, Louisa P. P. Selvadurai, Louise A. A. Corben, Martin B. B. Delatycki, Gary F. F. Egan, Ian H. H. Harding
Summary: In this study, we investigated the changes in functional connectivity between the cerebellum and cerebral cortex in individuals with Friedreich ataxia (FRDA). We found that altered connectivity in motor circuits was associated with disease severity and white matter damage in these patients.
JOURNAL OF NEUROLOGY
(2023)
Article
Oncology
Kimberly A. A. Miller, Angela A. A. Li, Katherine Y. Y. Wojcik, Julia Stal, Myles G. G. Cockburn, Gino K. K. In, David R. R. Freyer, Ann S. S. Hamilton, Joel E. E. Milam
Summary: This study examined the awareness and prevalence of skin cancer screening among young adult childhood cancer survivors, and found that adherence to recommended screening for skin cancer was low in this at risk population, especially among those exposed to radiotherapy. Therefore, effective strategies need to be developed to improve skin cancer screening rates in this high-risk population.
Article
Clinical Neurology
Chia-Jui Tsai, Hsiang-Yuan Lin, Isaac Wen-Yih Tseng, Susan Shur-Fen Gau
Summary: This study utilized canonical correlation analysis to demonstrate distinct multivariate associations between WM microstructural properties of a set of tracts and emotion dysregulation severity (diagnosis by ED interaction) in children with ADHD and typically developing controls. These tracts interconnect cortical regions involved in emotion processing, integration, and cognitive control across multiple brain systems. Impairment in WM microstructural integrity may be an essential correlate of emotion dysregulation in ADHD.
PROGRESS IN NEURO-PSYCHOPHARMACOLOGY & BIOLOGICAL PSYCHIATRY
(2021)
Article
Neurosciences
Andrea Escelsior, Alberto Inuggi, Maria Bianca Amadeo, Batya Engel-Yeger, Alice Trabucco, Davide Esposito, Claudio Campus, Anna Bovio, Sara Comparini, Beatriz Pereira da Silva, Gianluca Serafini, Monica Gori, Mario Amore
Summary: The study aims to examine the structural MRI correlates of sensory profiles in typically developed adults. The results show a significant correlation between sensation seeking and white matter integrity, but no correlation with whole brain cortical thickness.
FRONTIERS IN NEUROSCIENCE
(2023)
Article
Neuroimaging
Yu-Ling Chang, Ruei-Yi Chao, Yung-Chin Hsu, Ta-Fu Chen, Wen-Yih Isaac Tseng
Summary: This study investigated white matter microstructural integrity and cognitive correlates of memory awareness in older adults with or without mild cognitive impairment (MCI). While patients with MCI and poor awareness of memory deficits showed lower integrity in certain white matter fibers, the memory awareness deficits in MCI patients could not be solely explained by mnemonic anosognosia.
NEUROIMAGE-CLINICAL
(2021)
Article
Oncology
Yoonji Kim, Anamara Ritt-Olson, Jessica Tobin, Marcie Haydon, Joel Milam
Summary: This study investigated the correlates of well-being in young adult childhood cancer survivors, beyond depressive symptoms. The findings identified unique factors such as posttraumatic growth, social support, sense of adulthood, and self-rated health that were associated with well-being. These findings highlight the importance of considering broader aspects of well-being in psychosocial interventions and survivorship care for young adult childhood cancer survivors.
JOURNAL OF CANCER SURVIVORSHIP
(2023)
Article
Multidisciplinary Sciences
Garazi Labayru, Borja Camino, Antonio Jimenez-Marin, Joana Garmendia, Jorge Villanua, Miren Zulaica, Jesus M. Cortes, Adolfo Lopez de Munain, Andone Sistiaga
Summary: DM1 patients exhibit significant loss of WM integrity over time, with progressive anterior-posterior disconnection.
SCIENTIFIC REPORTS
(2022)
Article
Neurosciences
Mikael Noven, Hampus Olsson, Gunther Helms, Merle Horne, Markus Nilsson, Mikael Roll
Summary: The study found that language learning aptitude is related to cortical morphology and white matter microstructure, with vocabulary learning possibly correlated with cortical surface area in the left posterior-inferior precuneus. Phonetic memory, on the other hand, may be associated with the white matter tracts connecting cortical areas important for phonological working memory such as the left arcuate fasciculus and left superior longitudinal fasciculus III.
HUMAN BRAIN MAPPING
(2021)
Article
Neurosciences
Jing Chen, Anyan Ge, Ying Zhou, Yuanyuan Ma, Shaoping Zhong, Caizhong Chen, Weibin Shi, Jing Ding, Xin Wang
Summary: The study examined the relationships between cognitive function and white matter hyperintensity volume (WMHV) in patients with silent cerebrovascular disease, and found that impaired white matter integrity mediates the impact of WMHV on cognitive function. The findings suggest the importance of white matter integrity in cognitive rehabilitation strategies for patients with silent cerebrovascular diseases.
CNS NEUROSCIENCE & THERAPEUTICS
(2023)
Article
Oncology
L. M. E. van Erp, H. Maurice-Stam, L. C. M. Kremer, W. J. E. Tissing, H. J. H. van der Pal, L. Beek, A. C. H. de Vries, M. M. van den Heuvel-Eibrink, B. A. B. Versluys, M. van der Heiden-van der Loo, M. van Gorp, G. A. Huizinga, M. A. Grootenhuis
Summary: This study examined the support needs and associated factors of young adult childhood cancer survivors (YACCS) in the Netherlands. The results showed that YACCS had the strongest need for concrete information in the domains of lifestyle, fertility, and physical consequences of childhood cancer. The associated factors were mainly socioeconomic and psychosocial in nature. The study suggests that psychosocial care should be integrated into survivorship care for YACCS.
SUPPORTIVE CARE IN CANCER
(2022)