Review
Oncology
Mengyao Zhu, Shihao Sun, Yiheng Zhang, Lili Chen, Haiyan He, Juanjuan Chen, Ni Zhang, Meifen Zhang
Summary: Appearance care has positive immediate and short-term effects on self-esteem, anxiety, depression, and sexual function in breast cancer patients. However, its effects on body image and quality of life are uncertain.
SUPPORTIVE CARE IN CANCER
(2022)
Article
Psychology, Multidisciplinary
Elody Hutten, Ellen M. M. Jongen, Peter Verboon, Arjan E. R. Bos, Sanny Smeekens, Antonius H. N. Cillessen
Summary: This study found that developmental trajectories of loneliness in adolescence significantly predicted psychosocial functioning in young adulthood. Two different trajectories of loneliness were associated with risk of depression and self-esteem, while low-increasing loneliness was linked to risk of anxiety.
FRONTIERS IN PSYCHOLOGY
(2021)
Article
Psychology, Developmental
Helen Sharpe, Elian Fink, Fiona Duffy, Praveetha Patalay
Summary: Victimization by peers and siblings is associated with poorer mental health outcomes in adolescence. The study found that reducing victimization experiences can improve mental health outcomes for victims. It suggests the potential for bullying interventions in schools to limit the deterioration in mental health among victimized groups.
EUROPEAN CHILD & ADOLESCENT PSYCHIATRY
(2022)
Article
Dermatology
Crystal Zhou, Abhinav Vempati, Curtis Tam, Jeffrey Khong, Ruslan Vasilev, Kevin Tam, Sanam Hazany, Salar Hazany
Summary: Post-acne scarring is a common consequence of acne vulgaris with no universal cure. Recent advances in physically addressing acne scars have been made, but research on their psychosocial impacts is still lacking. A comprehensive PubMed search highlights known sources of mental distress caused by post-acne scarring and suggests that it requires a unique clinical approach separate from that used for active acne.
CLINICAL COSMETIC AND INVESTIGATIONAL DERMATOLOGY
(2023)
Article
Oncology
Anne Maas, Heleen Maurice-Stam, Leontien C. M. Kremer, Alied van der Aa-van Delden, Eline van Dulmen-den Broeder, Wim J. E. J. Tissing, Jacqueline Loonen, Helena J. H. van der Pal, Andrica C. H. M. de Vries, Marry van den Heuvel-Eibrink, Cecile Ronckers, Sebastian Neggers, Dorine Bresters, Marloes Louwerens, Margriet van der van der Loo, Marloes van Gorp, Martha Grootenhuis
Summary: This study compared the psychosocial outcomes of adult childhood cancer survivors with the general population and identified sociodemographic and medical risk factors. The results showed that childhood cancer survivors had similar self-esteem and anxiety levels, but were less depressed. However, their health-related quality of life was poorer, except for bodily pain. Factors such as female sex, lower education level, lack of relationship, and unemployment were negatively associated with most psychosocial outcomes. Few medical characteristics were found to be related to psychosocial outcomes, except for central nervous system tumor diagnosis. Future research should investigate additional factors such as coping, social support, and physical late effects in explaining the psychosocial functioning of cancer survivors.
Article
Psychology, Multidisciplinary
Sarah McDonald, Louise Sharpe, Carolyn MacCann, Alex Blaszczynski
Summary: This study explored the relationships between body image, personal investment, and psychosocial outcomes in individuals with amputations and diabetes using White's theoretical model. The results showed that body image disturbance mediated the relationship between personal investment and psychosocial outcomes, as well as between self-ideal discrepancy and psychosocial outcomes. The findings emphasize the importance of addressing body image in psychological interventions for individuals with health conditions.
FRONTIERS IN PSYCHOLOGY
(2021)
Article
Multidisciplinary Sciences
Yuxin Zhang, Jie Zhao, Nan Jiang, Yongyi Liu, Ting Wang, Xi Yu, Jiwei Wang, Jinming Yu
Summary: This study aimed to explore the association between types and numbers of comorbidities and stigma among breast cancer survivors. The results showed that participants with stroke, digestive diseases or musculoskeletal diseases had significantly higher stigma, and stigma was also higher among survivors with a greater number of comorbidities.
SCIENTIFIC REPORTS
(2022)
Article
Pediatrics
Christianne Milena Zulic-Agramunt, Iris Paola Guzman-Guzman, Pedro Delgado-Floody, Monserrat Belen Cerda Saavedra, Patricio Gutierrez De la Fuente, Mario Meza Solano, Claudia Sagredo Berrios, Carles Perez Testor
Summary: This study found that self-harm, low social and psychological well-being, and feeling mistreated by a boyfriend/girlfriend were associated with suicidality in Chilean adolescents.
Article
Psychiatry
Eun Hyun Seo, Seung-Gon Kim, Jae-Hon Lee, Chandlee C. Dickey, Mella Y. Kim, Ravneet Kaur Ghumman, Hyung-Jun Yoon
Summary: This study investigated the influence of psychosocial factors on medical students' quality of life. The results showed that higher levels of depression and Internet addiction were associated with lower scores in all domains of quality of life, while higher levels of self-esteem and social support were associated with higher scores. Certain sociodemographic factors also had significant effects on specific domains of quality of life. Educational strategies that focus on strengthening self-esteem and social support, as well as preventing depression and Internet addiction, may contribute to improving medical students' quality of life.
PSYCHIATRY INVESTIGATION
(2023)
Article
Nursing
Yunhee Jang, Mihyeon Seong, Sohyune Sok
Summary: This study examined the impact of body image and self-esteem on the quality of life of breast cancer patients who underwent breast reconstruction. The results showed that body image and self-esteem are important factors in determining the quality of life of these patients. In clinical practice, nurses should pay attention to the body image and self-esteem of breast cancer patients in order to enhance their quality of life.
JOURNAL OF CLINICAL NURSING
(2023)
Article
Obstetrics & Gynecology
Katja Linde, Franziska Lehnig, Michaela Nagl, Holger Stepan, Anette Kersting
Summary: Pregnancy can lead to changes in body image, both positive and negative. Factors such as self-esteem, worries, physical activity, and weight-related issues can impact body image dissatisfaction.
BMC PREGNANCY AND CHILDBIRTH
(2022)
Review
Psychology, Clinical
Min Kai Chan, Qian Hui Chew, Kang Sim
Summary: This systematic review examined resilience in bipolar disorder (BD) and its relationships with demographic, psychopathology, illness features, and psychosocial functioning. The findings suggested that higher resilience in BD was associated with specific psychopathology, clinical features, social factors, and psychosocial functioning. Therefore, enhancing resilience levels should be emphasized in the treatment of BD.
JOURNAL OF CLINICAL PSYCHIATRY
(2023)
Article
Dermatology
Eftychia Platsidaki, Vasiliki Efstathiou, Vasiliki Markantoni, Anargyros Kouris, Georgios Kontochristopoulos, Electra Nikolaidou, Dimitrios Rigopoulos, Alexandros Stratigos, Stamatios Gregoriou
Summary: This study aimed to assess the impact of melasma on depression, social anxiety, and self-esteem in the Greek population. The results showed that melasma patients had significantly higher levels of anxiety compared to healthy controls, while no differences were found in terms of depression or self-esteem. Furthermore, the severity of melasma was correlated with longer disease duration, higher levels of depression, and impaired health-related quality of life.
DERMATOLOGY AND THERAPY
(2023)
Article
Psychology, Multidisciplinary
Letizia Iannopollo, Grazia Cristaldi, Caterina Borgese, Samuela Sommacal, Giulia Silvestri, Samantha Serpentini
Summary: This article presents a case report of a breast cancer patient, highlighting the use of mindfulness-based interventions to improve her psychological well-being and quality of life. Through a combination of individual and group therapies, the patient received peer support and tools to manage her psychoemotional reactions.
BEHAVIORAL SCIENCES
(2022)
Article
Health Care Sciences & Services
Ewa Wojtyna, Malgorzata Pasek, Aleksandra Nowakowska, Anna Gozdzialska, Malgorzata Jochymek
Summary: Self-esteem is an important factor affecting the quality of life (QoL) for cancer patients undergoing surgical procedures for bodily deformities. However, little data exists on which aspects of self-esteem are most closely associated with QoL. This article presents two studies aimed at addressing this gap. Study 1 focuses on changes in global self-esteem and QoL in oral cancer patients (n = 35) treated surgically, while Study 2 examines changes in explicit and implicit self-esteem and QoL in women with breast cancer undergoing mastectomy (n = 96). Both studies used the EORTC QLQ-C30 and Rosenberg's SES questionnaires, with Study 2 also including the Implicit Association Test (IAT). Results showed that patients experienced a decline in global QoL and self-esteem after surgery. Study 1 revealed that patients with higher initial self-esteem experienced a greater decrease in self-esteem and QoL compared to those with lower initial self-esteem. In Study 2, women with fragile self-esteem exhibited the largest decreases in various dimensions of QoL and explicit self-esteem. Conversely, women with high explicit and implicit self-esteem had the best QoL after mastectomy. These findings highlight the need for special psycho-oncological care for cancer patients with high, fragile self-esteem.
Review
Pharmacology & Pharmacy
Patrick O. Perche, Madison K. Cook, Steven R. Feldman
Summary: This article reviews the efficacy and safety of abrocitinib as an oral medication for patients with moderate-to-severe atopic dermatitis. The study found that abrocitinib is effective in treating atopic dermatitis, with higher efficacy compared to other conventional medications, and has fewer side effects.
ANNALS OF PHARMACOTHERAPY
(2023)
Review
Pharmacology & Pharmacy
Alexandra Taylor, Rohan Singh, Steven R. Feldman
Summary: This review highlights the pharmacokinetics, efficacy, and safety of recently approved calcipotriene and betamethasone dipropionate (C-BD) cream in the treatment of psoriasis. The results showed that C-BD cream was effective and safe, with higher treatment success rates compared to C-BD topical suspension and vehicle. The use of C-BD cream provides a convenient and preferred option for patients with mild-to-moderate psoriasis.
ANNALS OF PHARMACOTHERAPY
(2023)
Review
Pharmacology & Pharmacy
Jessica N. Pixley, Taylor Schaetzle, Steven R. Feldman
Summary: This article reviews clinical trials on the efficacy, safety, and clinical application of once-daily roflumilast 0.3% cream for plaque psoriasis treatment. The results show that roflumilast is effective and safe, and it has potential as a nonsteroidal alternative to topical corticosteroids.
ANNALS OF PHARMACOTHERAPY
(2023)
Article
Infectious Diseases
Patrick O. Perche, Gabrielle M. Peck, Lillian Robinson, Ayman Grada, Alan B. Fleischer Jr, Steven R. Feldman
Summary: Acne vulgaris is a common reason for patients to seek care from dermatologists in the US, but referring providers may be hesitant to prescribe acne treatments or certain medications. A study analyzed prescription rates for acne therapies from 1993 to 2016 and found that younger patients and privately insured patients were more likely to receive prescription treatments. Dermatologists were more likely to recommend prescription medications compared to family medicine and pediatric providers. Oral minocycline and oral doxycycline were the most commonly prescribed antibiotics, while benzoyl peroxide was the most utilized and recommended over-the-counter drug for acne.
Editorial Material
Dermatology
Heli Patel, Steven R. Feldman
AMERICAN JOURNAL OF CLINICAL DERMATOLOGY
(2023)
Review
Pharmacology & Pharmacy
Christopher Alihosseini, Hannah Kopelman, Mallory Zaino, Steven R. Feldman
Summary: This study reviewed the safety and efficacy of avacopan for the treatment of ANCA-associated vasculitis. The results showed that avacopan can improve remission rates and reduce side effects caused by steroid use. Therefore, avacopan may be a new option for the treatment of ANCA-associated vasculitis.
ANNALS OF PHARMACOTHERAPY
(2023)
Review
Pharmacology & Pharmacy
Meghan C. Grossmann, Jessica N. Pixley, Steven R. Feldman
Summary: This article reviews the efficacy and safety of 1% tapinarof cream for plaque psoriasis. The results of two 12-week phase III clinical trials showed that around 35.4% to 40.2% of patients achieved clear or almost clear disease severity at week 12. In the 40-week, open-label extension trial, 40.9% of patients achieved a Physician's Global Assessment (PGA) score of 0 at least once. Tapinarof may be an effective and safe topical treatment for mild to severe plaque psoriasis.
ANNALS OF PHARMACOTHERAPY
(2023)
Letter
Dermatology
William B. Song, Gabrielle M. Peck, Aakriti Neopaney, Daniel B. Shin, Alan B. Fleischer Jr, Steven R. Feldman, Joel M. Gelfand, Hideki Mochizuki, James T. Elder, Yukinori Okada
JOURNAL OF INVESTIGATIVE DERMATOLOGY
(2023)
Letter
Dermatology
Emily A. Parks, Mallory L. Zaino, Jessica N. Pixley, Vani Mangalam Subramanian, Deepak Sirdeshmukh, Steven R. Feldman, Rita O. Pichardo
JOURNAL OF DERMATOLOGICAL TREATMENT
(2023)
Article
Dermatology
Rachel E. Tao, Jessica N. Pixley, Phillip G. Holovach, Alan B. Fleischer Jr, Steven R. Feldman
Summary: Off-label treatments are commonly used for pediatric psoriasis, with topical treatments, especially unapproved tacrolimus, being the most common approach. This may indicate a hesitance to use corticosteroids in children.
DERMATOLOGY AND THERAPY
(2023)
Review
Infectious Diseases
Rachel E. Tao, Stuti Prajapati, Jessica N. Pixley, Ayman Grada, Steven R. Feldman
Summary: Tetracycline-class drugs are commonly used in dermatology for treating skin diseases. This study reviewed the available evidence on whether taking these drugs with food affects their absorption and clinical efficacy. The study found that co-administration with food decreased systemic absorption of tetracycline, while the impact on doxycycline and minocycline varied. Oral sarecycline showed decreased absorption with food. Only sarecycline demonstrated limited or no impact of food intake on clinical efficacy. The study suggested considering patient adherence when choosing to take doxycycline, minocycline, and sarecycline with food.
Review
Pharmacology & Pharmacy
Rithi J. J. Chandy, Diem-Phuong D. Dao, Cristian C. C. Rivis, Divya M. M. Shan, Steven R. R. Feldman
Summary: The objective of this study was to compare the safety and efficacy of noncorticosteroid topical treatments for plaque psoriasis. A literature search was conducted, and relevant articles and clinical trial data were analyzed. Six classes of noncorticosteroid topicals were studied, and the results showed that they are effective and safe for treating plaque psoriasis.
JOURNAL OF PHARMACY TECHNOLOGY
(2023)
Review
Biochemistry & Molecular Biology
Heli A. A. Patel, Rishab R. R. Revankar, Sofia T. T. Pedroza, Shaveonte Graham, Steven R. R. Feldman
Summary: Understanding the genetic factors in psoriasis can help improve targeted treatment strategies. This review discusses the genes associated with psoriasis pathogenesis and their connection to available treatment options. Searching various databases, relevant genetic markers and treatments were identified. Gene variants involved in inflammatory pathways, such as interleukins and interferons, are commonly implicated in psoriasis. Some treatments, like IL23 and TYK2 inhibitors, target genes associated with psoriasis. Multiple genes are involved in psoriasis pathogenesis, providing potential avenues for developing new treatment strategies and improving outcomes.
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
(2023)
Article
Dermatology
Rachel E. Tao, Jessica N. Pixley, Christina L. Kontzias, Steven R. Feldman
Summary: Drug efficacy is best evaluated through randomized, controlled, double-blind clinical trials, while safety assessment is more challenging. The Medical Dictionary for Regulatory Activities (MedDRA) is used to track and categorize adverse events (AE) during clinical trials. This study reviewed recent clinical trials on atopic dermatitis to demonstrate the importance of understanding MedDRA in evaluating adverse events related to herpes simplex virus (HSV) infection.
ARCHIVES OF DERMATOLOGICAL RESEARCH
(2023)
Review
Dermatology
Gaurav N. Pathak, Rithi J. Chandy, Vidisha Naini, Steven R. Feldman, Babar K. Rao
Summary: This study analyzed clinical trials on vitiligo and found that less than half of the trials used quality of life (QoL) assessments, with DLQI and CDLQI being the commonly used tools. As the number of trials increases, vitiligo-specific questionnaires may be more suitable for evaluating unique vitiligo-related concerns.
DERMATOLOGIC THERAPY
(2023)
