Article
Dermatology
Allen G. Strickler, Payal Shah, Shirin Bajaj, Richard Mizuguchi, Rajiv Nijhawan, Mercy Odueyungbo, Anthony Rossi, Desiree Ratner
Summary: Cutaneous surgery is crucial for comprehensive dermatologic care, and dermatologists must be well-prepared to manage and prevent risks associated with surgical procedures to avoid complications. This review focuses on preventing surgical complications both pre-and postoperatively, as well as during the surgical procedure.
JOURNAL OF THE AMERICAN ACADEMY OF DERMATOLOGY
(2021)
Article
Cardiac & Cardiovascular Systems
Larry M. Baddour, Imre Janszky, Martin H. Thornhill, Zerelda Esquer Garrigos, Daniel C. Desimone, Karen Welty-Wolf, Annette L. Baker, Pei-Ni Jone, Bernard Prendergast, Mark J. Dayer
Summary: There is currently no published prospective randomized clinical trial that has established the association between invasive dental and nondental invasive procedures and the risk of infective endocarditis. The efficacy and safety of antibiotic prophylaxis in preventing infective endocarditis in high-risk patients during invasive procedures have not been defined. Recent investigations from Sweden and England have shown an association between nondental invasive procedures and the subsequent development of infective endocarditis.
Review
Dermatology
Justin Gabriel Schlager, Daniela Hartmann, Virginia Ruiz San Jose, Kathrin Patzer, Lars E. French, Benjamin Kendziora
Summary: This study analyzed whether specific procedure-related factors are associated with surgical site infections (SSIs). The results showed that local flaps, skin grafting, and severely contaminated surgical sites have a higher risk for SSI, while second intention healing and probably delayed wound closure are not associated with postoperative wound infection.
DERMATOLOGIC SURGERY
(2022)
Review
Dermatology
Isabella Dreyfuss, Amanda Ramnot, Philippe H. Jean-Pierre, Fabio Frech, Loren Hernandez, Keyvan Nouri
Summary: Antibiotics are commonly used in dermatologic procedures, but their specific usage and dosage depend on the procedure, diagnosis, and patient's condition. Current guidelines aim to address contraindications and explore alternative methods to prevent antibiotic resistance.
DERMATOLOGIC THERAPY
(2022)
Article
Surgery
Seema P. Anandalwar, Carly Milliren, Dionne A. Graham, Jason G. Newland, Katherine He, Jonathan L. Hills-Dunlap, Mark A. Kashtan, Shawn J. Rangel
Summary: This study aimed to quantify inappropriate antimicrobial prophylaxis utilization at the procedure level in pediatric surgery in order to identify high-priority targets for stewardship efforts. The analysis revealed that cholecystectomy, inguinal hernia repair, and procedures involving the small and large bowel were the main procedures with inappropriate antimicrobial utilization, and should be prioritized for antimicrobial stewardship efforts.
Review
Dermatology
Christoph R. Loeser, Soeren L. Becker, Daniela Hartmann, Lukas Kofler, Christian Kunte, Cornelia S. L. Mueller, Justin Gabriel Schlager, Galina Balakirski
Summary: The aim of perioperative antibiotic prophylaxis is to prevent surgical site infections or other infectious complications. While effective in high infection rate surgeries, the general surgical recommendations do not fully address the needs of dermatologic surgery. Unlike the US, there are currently no specific guidelines for perioperative antibiotic prophylaxis in dermatologic surgery in Germany, leading to diverse use of antimicrobial substances guided by surgeons' experience.
JOURNAL DER DEUTSCHEN DERMATOLOGISCHEN GESELLSCHAFT
(2023)
Review
Infectious Diseases
Andrea Polistena, Francesco Paolo Prete, Stefano Avenia, Giuseppe Cavallaro, Giovanna Di Meo, Alessandro Pasculli, Fabio Rondelli, Alessandro Sanguinetti, Lucia Ilaria Sgaramella, Nicola Avenia, Mario Testini, Angela Gurrado
Summary: This systematic review analyzed the impact of antibiotic prophylaxis on postoperative surgical site infection (SSI) rates in thyroid and parathyroid surgery. The meta-analysis of multiple studies found no significant difference in SSI rates between the group receiving antibiotic prophylaxis and the group without preoperative antibiotics. Low-quality evidence supports the similar SSI rates produced by antibiotic prophylaxis in these surgeries compared to the absence of perioperative antibiotics.
Article
Medicine, General & Internal
Alan T. N. Tita, Waldemar A. Carlo, Elizabeth M. McClure, Musaku Mwenechanya, Elwyn Chomba, Jennifer J. Hemingway-Foday, Avinash Kavi, Mrityunjay C. Metgud, Shivaprasad S. Goudar, Richard Derman, Adrien Lokangaka, Antoinette Tshefu, Melissa Bauserman, Carl Bose, Poonam Shivkumar, Manju Waikar, Archana Patel, Patricia L. Hibberd, Paul Nyongesa, Fabian Esamai, Osayame A. Ekhaguere, Sherri Bucher, Saleem Jessani, Shiyam S. Tikmani, Sarah Saleem, Robert L. Goldenberg, Sk M. Billah, Ruth Lennox, Rashidul Haque, William Petri, Lester Figueroa, Manolo Mazariegos, Nancy F. Krebs, Janet L. Moore, Tracy L. Nolen, Marion Koso-Thomas
Summary: In women planning a vaginal delivery, a single oral dose of azithromycin significantly reduced the risk of maternal sepsis or death compared to placebo, but had little effect on newborn sepsis or death.
NEW ENGLAND JOURNAL OF MEDICINE
(2023)
Article
Orthopedics
Felix Rohrer, Anita Maurer, Hubert Noetzli, Brigitta Gahl, Andreas Limacher, Tanja Hermann, Jan Bruegger
Summary: The use of prolonged surgical antibiotic prophylaxis (PSAP) in orthopaedic surgery, despite guidelines advising against it, was found to be 12% in this study. Patient-related factors associated with PSAP use included older age, higher BMI, ASA classification >= 3, and lung disease, while surgery-related factors included use of prosthetics, knee surgery, longer surgery duration, and presence of drains. All four surgical site infections (SSI) occurred in the SAP group, indicating a potentially lower SSI risk in the PSAP group. Surgeons varied in their frequencies of administering PSAP, suggesting differing approaches to antibiotic prophylaxis.
BMC MUSCULOSKELETAL DISORDERS
(2021)
Article
Infectious Diseases
Jose Pablo Diaz-Madriz, Esteban Zavaleta-Monestel, Jorge Arturo Villalobos-Madriz, Carolina Rojas-Chinchilla, Priscilla Castrillo-Portillo, Alison Melendez-Alfaro, Ana Fernanda Vasquez-Mendoza, Gabriel Munoz-Gutierrez, Sebastian Arguedas-Chacon
Summary: This study aimed to evaluate the impact of an antimicrobial stewardship program on the selection of surgical antibiotic prophylaxis in adult patients. The implementation of the program showed positive results in improving the selection and duration of antibiotics for surgical prophylaxis, as well as other related variables.
Review
Dermatology
Galina Balakirski, Soren L. Becker, Daniela Hartmann, Lukas Kofler, Christian Kunte, Cornelia S. L. Mueller, Thomas Volz, Benjamin Kendziora, Justin Gabriel Schlager, Christoph R. R. Loeser
Summary: This article discusses specific indications for the use of perioperative antibiotic prophylaxis (PAP) in skin surgery, including patients who have undergone heart valve replacement or experienced bacterial endocarditis. It also provides recommendations for the administration of PAP in special situations based on current scientific literature.
JOURNAL DER DEUTSCHEN DERMATOLOGISCHEN GESELLSCHAFT
(2023)
Review
Cardiac & Cardiovascular Systems
Walter R. Wilson, Michael Gewitz, Peter B. Lockhart, Ann F. Bolger, Daniel C. DeSimone, Dhruv S. Kazi, David J. Couper, Andrea Beaton, Catherine Kilmartin, Jose M. Miro, Craig Sable, Mary Anne Jackson, Larry M. Baddour
Summary: After reviewing the available evidence, no changes are recommended to the 2007 guidelines for preventing Viridans Group Streptococcal Infective Endocarditis. It is still advised to use antibiotic prophylaxis for high-risk patients, emphasizing the importance of oral health in disease prevention. Further randomized controlled studies are needed to refine recommendations.
Review
Medicine, General & Internal
Paolo Paioni, Christoph Aebi, Julia Bielicki, Michael Buettcher, Pierre Alex Crisinel, Christian R. Kahlert, Noemie Wagner, Christoph Berger
Summary: Infection following surgical procedures is a significant concern for patients of all ages. The use of sterile techniques, antibiotic prophylaxis, and improved postoperative wound care has helped reduce the incidence of surgical site infections over time. However, there is a lack of recommendations for perioperative antimicrobial prophylaxis in the pediatric population. This article provides a standardized approach to the effective use of antimicrobial agents for preventing surgical site infections in children, aiming to promote targeted and rational antibiotic use in Switzerland.
SWISS MEDICAL WEEKLY
(2022)
Article
Public, Environmental & Occupational Health
Antonelle Pardo, Vianney Ntabaza, Mathieu Rivolta, Aline Goulard, Serge Stenuit, Remy Demeester, Sandrine Milas, Pierre Duez, Stephanie Patris, Marc Joris, Philippe Dony, Soraya Cherifi
Summary: This study analyzed the use of surgical antibiotic prophylaxis in a Belgian hospital from 2016 to 2021 and evaluated the impact of stewardship interventions. The results showed that a combined intervention strategy involving pharmacists significantly increased compliance with guidelines, but the effects were not fully sustained after discontinuation of the interventions.
ANTIMICROBIAL RESISTANCE AND INFECTION CONTROL
(2022)
Article
Cardiac & Cardiovascular Systems
Radoslaw Jaworski, Katarzyna Dzierzanowska-Fangrat, Agnieszka Czajkowska, Bohdan Maruszewski, Andrzej Kansy
Summary: The study found that extrapolating antibiotic prophylaxis recommendations from adults to children may lead to suboptimal antibiotic concentrations. It is necessary to consider the volume of extracorporeal circulation priming when determining the dose of cefazolin for pediatric cardiac surgery.
EUROPEAN JOURNAL OF CARDIO-THORACIC SURGERY
(2022)