Article
Public, Environmental & Occupational Health
Yuko Akiyama, Yuta Norimatsu, Yuki Ohno
Summary: This study investigated whether prophylactic antibiotic use after punch biopsies reduces the risk of surgical site infections (SSIs). The results suggest that the incidence of SSIs in punch biopsies without prophylaxis seems to be low. However, further research is needed due to the small number of cases in this study.
ANTIMICROBIAL RESISTANCE AND INFECTION CONTROL
(2022)
Article
Surgery
Abdelaziz Atwez, Kayla Antosz, Lindsey Cooper, Paulina Le, Tarik Mujadzic, Jackson Seagle, Mirsad Mujadzic, Harold Friedman
Summary: Compared with other facial fractures, mandibular fractures have the highest rate of postsurgical site infection. There is conflicting data regarding the role of prophylactic preoperative antibiotics in reducing rates of surgical site infections (SSIs). This study compares the rate of infections in patients who underwent mandibular fracture repair and received different antibiotic treatments.
ANNALS OF PLASTIC SURGERY
(2023)
Article
Dermatology
Edward W. Seger, Brett C. Neill, Soham Patel, Spyros M. Siscos, Thomas L. H. Hocker
Summary: Most patients undergoing Mohs surgery were willing to attempt home suture removal and were more willing, confident, and less anxious after viewing educational resources. Patients with previous suture removal experience were more likely to attempt removal after their procedure, and 97% of patients who were willing were successful. No major complications were reported.
DERMATOLOGIC SURGERY
(2022)
Article
Gastroenterology & Hepatology
Martin Rutegard, Alethea Tang, Darren James Gregoire, Christopher Stewart, Libor Hurt, Susan Chandler, Matthew David Hitchings, Brendan Healy, Dean Harris
Summary: The study aims to evaluate the impact of oral antibiotics on the incidence of surgical site infections in colorectal surgery. The results show that the use of oral antibiotics in colorectal surgery may reduce the risk of infection and alter the structure of the intestinal microbiome. However, further research is needed on the application methods of different oral antibiotics and the mechanism of the gut microbiome.
INTERNATIONAL JOURNAL OF COLORECTAL DISEASE
(2023)
Article
Dentistry, Oral Surgery & Medicine
Andreas Naros, Carola Helene Naros, Daniel Awad, Michael Krimmel, Susanne Kluba
Summary: This retrospective study evaluated the incidence of surgical site infections (SSI) and associated risk factors in orthognathic surgery. Low rates of SSIs were found following an intraoperative single-dose antibiotic prophylaxis. Postoperative infections were significantly associated with type of surgery, type of drainage, smoking, and previous surgically assisted rapid palatal expansion (SARPE). No significant relationships were observed between infections and antibiotic regime, age at surgery, gender, craniofacial malformations, surgery duration, displacement distances, and mandibular setback vs. advancement.
Article
Dermatology
Alexander Hicks, Anika Mazumder, Rylee Moody, Krithika Kumanan, Ramona Behshad
Summary: Gram-negative surgical site infections (SSIs) after Mohs micrographic surgery (MMS) may have more subtle clinical features compared with typical gram-positive infections. Having a low threshold for obtaining wound culture for edematous or painful postoperative wounds may help in detecting potentially overlooked gram-negative infections.
DERMATOLOGIC SURGERY
(2023)
Article
Pharmacology & Pharmacy
Kyung Mi Kim, Sung-Hoon Kim, Ho-Yong Yun, Jiwon Jung, Ji-Yeon Bang, Eun-Kyung Lee, Byung-Moon Choi, Gyu-Jeong Noh
Summary: This study aimed to construct a pharmacokinetic model of cefoxitin for colorectal surgical patients using the TCI method, and found that TCI method has a significantly higher fraction of time maintaining free cefoxitin concentration above the minimum inhibitory concentration compared to the standard method.
BRITISH JOURNAL OF CLINICAL PHARMACOLOGY
(2021)
Article
Public, Environmental & Occupational Health
David K. Warren, Kate M. Peacock, Katelin B. Nickel, Victoria J. Fraser, Margaret A. Olsen
Summary: Prophylactic antibiotics are commonly prescribed at discharge for mastectomy, with anti-MSSA antibiotics associated with decreased risk of surgical-site infection (SSI) for both mastectomy-only and mastectomy with immediate reconstruction patients. High numbers needed to treat indicate potential benefits of postdischarge antibiotics should be weighed against potential harms of antibiotic overuse.
INFECTION CONTROL AND HOSPITAL EPIDEMIOLOGY
(2022)
Review
Obstetrics & Gynecology
N. Islam, L. Furuya-Kanamori, S. Mahmood, L. Thalib
Summary: Prophylactic antibiotics are effective in reducing post-abortion GTI among women undergoing surgical procedures for incomplete abortion, especially in high-income countries. However, the effect is not significant in low- and middle-income countries, and more studies are needed for confirmation.
BJOG-AN INTERNATIONAL JOURNAL OF OBSTETRICS AND GYNAECOLOGY
(2021)
Review
Biochemistry & Molecular Biology
Simran Grewal, J. Reinder D. Reuvers, Gabor S. A. Abis, Rene H. J. Otten, Geert Kazemier, Hein B. A. C. Stockmann, Marjolein van Egmond, Steven J. Oosterling
Summary: Prophylactic oral antibiotics combined with mechanical bowel preparation can reduce the rates of surgical-site infection and anastomotic leakage in patients undergoing elective colorectal carcinoma surgery, with selective decontamination of the digestive tract showing greater effectiveness in reducing anastomotic leakage compared to broad-spectrum antibiotics.
Article
Infectious Diseases
Marco Lollobrigida, Gianluca Pingitore, Luca Lamazza, Giulia Mazzucchi, Giorgio Serafini, Alberto De Biase
Summary: The benefit of antibiotic prophylaxis for most oral surgical procedures is controversial, with substantial agreement found in some clinical scenarios but discordant responses in others. Specific guidelines on antibiotics in dentistry, particularly on antibiotic prophylaxis in oral surgery, are needed to avoid unnecessary prescriptions, as indicated by the heterogeneous responses collected from the survey sample.
Article
Immunology
Tong Niu, Yuelun Zhang, Ziquan Li, Yanyan Bian, Jianguo Zhang, Yipeng Wang
Summary: This study analyzed the use of alternative antibiotics in patients with penicillin allergy undergoing orthopedic surgeries and its relationship with surgical site infection (SSI). The results showed that patients with penicillin allergy had a higher risk of postoperative SSI, especially deep SSI, compared to patients without penicillin allergy. The increased infection rate may be attributed to the use of alternative prophylactic antibiotics.
FRONTIERS IN CELLULAR AND INFECTION MICROBIOLOGY
(2023)
Review
Clinical Neurology
Elizabeth Duquette, Pravjit Bhatti, Samir Sur, Daniel R. Felbaum, Ehsan Dowlati
Summary: This study reviewed the literature on the usage of antibiotic irrigation in neurosurgical operations. The results showed that antibiotic irrigation can reduce the incidence of surgical site infections in neurosurgery. However, the generalizability of these results is limited due to the variations in study methods and limitations. Further randomized control trials are needed to determine the best practices for antibiotic irrigation in neurosurgical procedures.
WORLD NEUROSURGERY
(2022)
Article
Surgery
Manuel O. O. Jakob, Adriana Bruggemann, Nina Moser, Daniel Candinas, Guido Beldi, Tobias Haltmeier
Summary: This study revealed that emergency hospitalization, previous laparotomy, duration of operation, laparotomy, bariatric, colorectal, and emergency surgery, as well as abdominal contamination or infection, and usage of non-polypropylene mesh were independent predictors for surgical site infection (SSI) following intra-abdominal onlay mesh implantation. In contrast, hernia surgery was associated with a lower risk for SSI.
SURGICAL ENDOSCOPY AND OTHER INTERVENTIONAL TECHNIQUES
(2023)
Article
Infectious Diseases
Margaret A. Olsen, Jacob K. Greenberg, Kate Peacock, Katelin B. Nickel, Victoria J. Fraser, David K. Warren
Summary: This study aims to investigate the prevalence and factors associated with post-discharge prophylactic antibiotic use after spinal fusion, as well as its relationship with the risk of surgical site infection (SSI). Data from the MarketScan Commercial Database were analyzed, and it was found that post-discharge prophylactic antibiotic use was not associated with decreased SSI risk.
JOURNAL OF ANTIMICROBIAL CHEMOTHERAPY
(2022)