Article
Pediatrics
Sarah Kristine Norgaard, Nadja Hawwa Vissing, Bo Lund Chawes, Jakob Stokholm, Klaus Bonnelykke, Hans Bisgaard
Summary: Childhood illness imposes a significant economic burden on society. A study on 700 children investigated the economic impact of illness in the first three years of life, finding that factors such as fish-oil supplementation during pregnancy, gestational age, and birth weight were associated with reduced costs, while cesarean delivery was associated with higher costs. Targeting perinatal risk factors may help reduce the financial burden of common childhood illnesses.
Article
Allergy
Laure M. Fijen, Philip C. G. Klein, Danny M. Cohn, Tim A. Kanters
Summary: This study aims to establish the entire burden of hereditary angioedema (HAE) which includes disease control, treatment satisfaction, reductions in quality of life, and societal costs. A cross-sectional survey was conducted on adult patients with HAE under treatment at the Dutch national center of reference, and the results provide valuable information for reimbursement decisions for HAE treatments.
JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY-IN PRACTICE
(2023)
Article
Health Care Sciences & Services
Mabel Aoun, Elie Helou, Ghassan Sleilaty, Rony M. Zeenny, Dania Chelala
Summary: This study estimated the cost of illness of all stages of CKD in Lebanon and found a high burden of hemodialysis and peritoneal dialysis cost. The study also revealed a significantly higher cost of medications in transplant patients.
BMC HEALTH SERVICES RESEARCH
(2022)
Review
Clinical Neurology
Steven Simoens
Summary: The economic burden of multiple sclerosis is substantial, with costs increasing with disease severity and influenced by relapses and therapy adherence. Cost estimates vary between countries, and disease-modifying therapies are generally not cost-effective for relapsing-remitting multiple sclerosis, depending on the local setting.
FRONTIERS IN NEUROLOGY
(2022)
Article
Public, Environmental & Occupational Health
May Phyu Sin, Md Zahid Hasan, Birger C. Forsberg
Summary: This study examined the change in the societal economic burden of under-five diarrhoea in Bangladesh from 2007 to 2018. It found a 36.4% reduction in the economic burden, but it still accounted for 0.29% of the country's gross domestic product in 2018. Premature deaths were the major contributor to the costs.
JOURNAL OF GLOBAL HEALTH
(2023)
Article
Clinical Neurology
Mario Alberto Battaglia, Daiana Bezzini, Isabella Cecchini, Cinzia Cordioli, Francesca Fiorentino, Tommaso Manacorda, Mihaela Nica, Michela Ponzio, Daniela Ritrovato, Chiara Vassallo, Francesco Patti
Summary: This study estimates the burden and cost of illness of multiple sclerosis (MS) in Italy in 2019 from a societal perspective. The results show a significant impact of the disease on patients' daily activities and work, increasing with disability. Fatigue is identified as a major burden. The overall cost of the disease in Italy is estimated at 4.8 billion euros.
JOURNAL OF NEUROLOGY
(2022)
Article
Hematology
Laura H. Bukkems, Kathelijn Fischer, Idske Kremer-Hovinga, Anouk A. M. Donners, Karin Fijnvandraat, Roger E. G. Schutgens, Marjon H. Cnossen, Ron A. A. Mathot
Summary: The study developed a cost-efficient alternative dosing regimen for emicizumab maintenance, which achieved similar plasma concentrations compared to the registered dosing regimen and saved costs for patients.
THROMBOSIS AND HAEMOSTASIS
(2022)
Article
Clinical Neurology
Esme Fuller-Thomson, Lauren Carrique, Andie MacNeil
Summary: There is a high comorbidity between ADHD and GAD, highlighting the need for targeted interventions to support these often overlapping disorders.
JOURNAL OF AFFECTIVE DISORDERS
(2022)
Article
Health Care Sciences & Services
Argerie Tsimicalis, Michael Gasse, Marilyn Morand, Frank Rauch
Summary: This study describes the financial impacts of osteogenesis imperfecta (OI) and highlights the effectiveness of crowdfunding platforms in alleviating costs. The results emphasize the need for further research to better understand OI costs and provide economic support for individuals with OI.
Article
Health Care Sciences & Services
Christoffer Bugge, Erik Magnus Saether, Odd Terje Brustugun, Ivar Sonbo Kristiansen
Summary: This study aimed to estimate and reveal the societal costs of cancer, with indirect costs almost as high as direct costs. The value of lost life years and quality of life represents the greatest cost, along with other commonly omitted costs such as informal nursing, patient time costs, and excess costs of using public funds.
Article
Health Care Sciences & Services
Jordan Everson, Robert J. Besaw, Christine C. Whitmore, T. Joseph Mattingly II, Anna D. Sinaiko, Nancy L. Keating, Nicole Senft Everson, Stacie B. Dusetzina
Summary: This study examined the experiences of 1,020 older adults in discussing medication costs with their healthcare team. Results showed that 43% of respondents found prior conversations difficult to understand, 3% felt their healthcare team was not respectful, and 48% felt there was not enough time for the discussion. Those who had difficulty understanding or felt that their clinician was not respectful were less interested in future discussions. Only 6% and 10% of respondents were comfortable discussing medication prices with financial counselors or social workers, respectively.
JOURNAL OF GENERAL INTERNAL MEDICINE
(2023)
Article
Immunology
Daniela Olivera Mesa, Peter Winskill, Azra C. Ghani, Katharina Hauck
Summary: This study estimated the societal costs of vaccine refusal using measles as a case study. The findings showed that even small reductions in vaccine uptake can result in large outbreaks of infectious diseases. In the case study of England, each vaccine refusal imposed a societal loss of GBP 292 million and a disease burden of 17,630 quality-adjusted-life-years over a 20 year time horizon.
Article
Geriatrics & Gerontology
Stephanie Nothelle, Evan Bollens-Lund, Kenneth E. Covinsky, Amy Kelley
Summary: This study examines the co-occurrence of dementia and other manifestations of serious illness in older adults, and its impact on healthcare utilization, Medicare costs, caregiving hours, and out-of-pocket expenses. Findings indicate that the majority of individuals with dementia (67%) also have other serious illnesses. Those with dementia and advanced medical conditions had the highest hospital utilization and Medicare costs.
JOURNAL OF THE AMERICAN GERIATRICS SOCIETY
(2023)
Article
Multidisciplinary Sciences
Xavier Sanchez, Gerardine Leal, Angel Padilla, Ruth Jimbo
Summary: The objective of this study was to estimate the direct medical cost per episode and the annual cost for acute diarrhea in children under five in Ambulatory Care Centers of the Ministry of Public Health of Ecuador. The study found that a high proportion of the direct medical cost of acute diarrhea in children under five in outpatient settings is due to unnecessary laboratory tests.
Article
Clinical Neurology
Till Wagner, Nele Assmann, Sandra Koehne, Anja Schaich, Daniel Alvarez-Fischer, Stefan Borgwardt, Arnoud Arntz, Ulrich Schweiger, Eva Fassbinder
Summary: This study focuses on the high cost-of-illness associated with borderline personality disorder (BPD), finding that in Germany, each BPD patient incurred costs of euro 31,130 per year before receiving disorder-specific outpatient treatment. Direct costs, mainly related to hospital treatment, accounted for 54.8%, while indirect costs, with work disability as a key driver, made up 45.2% of the total costs. The study emphasizes the significant economic burden of BPD and highlights the importance of addressing both direct and indirect costs for societal impact.
EUROPEAN ARCHIVES OF PSYCHIATRY AND CLINICAL NEUROSCIENCE
(2022)
Article
Cardiac & Cardiovascular Systems
Benjamin S. Wessler, Lana Y. H. Lai, Whitney Kramer, Michael Cangelosi, Gowri Raman, Jennifer S. Lutz, David M. Kent
CIRCULATION-CARDIOVASCULAR QUALITY AND OUTCOMES
(2015)
Review
Psychiatry
M. Fridman, P. S. Hodgkins, J. S. Kahle, M. H. Erder
EUROPEAN PSYCHIATRY
(2015)
Article
Health Care Sciences & Services
James D. Chambers, Matthew Chenoweth, Michael J. Cangelosi, Junhee Pyo, Joshua T. Cohen, Peter J. Neumann
Article
Health Care Sciences & Services
James D. Chambers, Michael J. Cangelosi, Peter J. Neumann
Article
Health Care Sciences & Services
James D. Chambers, Matthew D. Chenoweth, Junhee Pyo, Michael J. Cangelosi, Peter J. Neumann
INTERNATIONAL JOURNAL OF TECHNOLOGY ASSESSMENT IN HEALTH CARE
(2015)
Article
Cardiac & Cardiovascular Systems
Benjamin S. Wessler, Lana Y. H. Lai, Whitney Kramer, Michael Cangelosi, Gowri Raman, Jennifer S. Lutz, David M. Kent
CIRCULATION-CARDIOVASCULAR QUALITY AND OUTCOMES
(2015)
Review
Respiratory System
Donald R. VanDevanter, Jennifer S. Kahle, Amy K. O'Sullivan, Slaven Sikirica, Paul S. Hodgkins
JOURNAL OF CYSTIC FIBROSIS
(2016)
Article
Allergy
Robert M. Niven, Michael R. Simmonds, Michael J. Cangelosi, Dominic P. Tilden, Suzanne Cottrell, Narinder S. Shargill
Article
Multidisciplinary Sciences
L. Eugene Arnold, Paul Hodgkins, Herve Caci, Jennifer Kahle, Susan Young
Article
Health Care Sciences & Services
Michael J. Cangelosi, Jesse D. Ortendahl, Lisa M. Meckley, Tanya G. K. Bentley, Ayanna M. Anene, Kelly M. Shriner, John Fox
EXPERT REVIEW OF PHARMACOECONOMICS & OUTCOMES RESEARCH
(2015)
Review
Respiratory System
Ranjani Somayaji, Michael D. Parkins, Anand Shah, Stacey L. Martiniano, Michael M. Tunney, Jennifer S. Kahle, Valerie J. Waters, J. Stuart Elborn, Scott C. Bell, Patrick A. Flume, Donald R. VanDevanter
JOURNAL OF CYSTIC FIBROSIS
(2019)
Review
Biochemistry & Molecular Biology
Britney N. Lizama, Jennifer Kahle, Susan M. Catalano, Anthony O. Caggiano, Michael Grundman, Mary E. Hamby
Summary: There is a significant medical need to develop disease-modifying treatment options for age-related degenerative diseases of the central nervous system. The sigma-2 receptor plays a role in regulating cell functions and has potential as a therapeutic target for Alzheimer's disease, a-synucleinopathies, and dry age-related macular degeneration.
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
(2023)
Article
Gastroenterology & Hepatology
Ananya Das, Michael J. Cangelosi, V. Raman Muthusamy
Summary: The study aimed to estimate the cost-effectiveness of EXALT in the US healthcare system. The results showed that EXALT is a viable and cost-effective strategy for Endoscopic Retrograde Cholangiopancreatography (ERCP), especially with the support of device-specific reimbursement. It can reduce the net costs for hospitals while maintaining QALY gains.
TECHNIQUES AND INNOVATIONS IN GASTROINTESTINAL ENDOSCOPY
(2022)
Article
Critical Care Medicine
Robert Kruklitis, Kim French, Michael Joseph Cangelosi, Kevin L. Kovitz
Article
Oncology
J. M. Martinez, A. Anene, T. G. K. Bentley, M. J. Cangelosi, L. M. Meckley, J. D. Ortendahl, A. J. Montero
JOURNAL OF GASTROINTESTINAL CANCER
(2017)