Article
Medicine, General & Internal
Edith Lopez-Toro, Casper J. H. Wolf, Rafael A. Gonzalez, Wim van den Brink, Arnt Schellekens, Maria C. Velez-Pastrana
Summary: This study used network analysis to examine the relationships between symptoms of substance use disorders (SUD) and other psychiatric conditions. The findings support the current diagnostic classification system, but also suggest the need for future research to include a broader range of symptoms and explore changes in symptom networks during treatment.
JOURNAL OF CLINICAL MEDICINE
(2022)
Article
Medicine, General & Internal
Daniela P. R. Chieffo, Federica Moriconi, Marika Pane, Simona Lucibello, Elisabetta Ferraroli, Giulia Norcia, Martina Ricci, Anna Capasso, Gianpaolo Cicala, Bianca Buchignani, Giorgia Coratti, Costanza Cutrona, Monia Pelizzari, Claudia Brogna, Jos G. M. Hendriksen, Francesco Muntoni, Eugenio Mercuri
Summary: The aim of this study was to evaluate the consistency of intellectual functioning in DMD boys over time and its relationship to behavioral and neuropsychiatric difficulties. The findings indicate that there are changes in IQ in DMD patients, which are likely to be associated with behavioral and attention deficits.
JOURNAL OF CLINICAL MEDICINE
(2023)
Article
Pharmacology & Pharmacy
Emmi Kujala, Helina Hakko, Pirkko Riipinen, Kaisa Riala
Summary: We conducted a study to explore factors associated with benzodiazepine (BZD) use during late adolescence and early adulthood. The study included 508 adolescents admitted to psychiatric inpatient care between April 2001 and March 2006. Results showed that heavy BZD use in males was associated with substance-use disorder and parents' psychiatric problems, while heavy use in females was linked to conduct disorder, being a bully/bully-victim, and parental substance-use problems. The study also highlighted the importance of cautious prescribing of BZDs to young adults, as heavy BZD use was associated with female suicide attempts.
INTERNATIONAL CLINICAL PSYCHOPHARMACOLOGY
(2023)
Article
Multidisciplinary Sciences
Ditte Demontis, Raymond K. Walters, Veera M. Rajagopal, Irwin D. Waldman, Jakob Grove, Thomas D. Als, Soren Dalsgaard, Marta Ribases, Jonas Bybjerg-Grauholm, Maria Baekvad-Hansen, Thomas Werge, Merete Nordentoft, Ole Mors, Preben Bo Mortensen, Bru Cormand, David M. Hougaard, Benjamin M. Neale, Barbara Franke, Stephen Faraone, Anders D. Borglum
Summary: This study identified three genome-wide significant loci for ADHD comorbid with DBDs, with one locus on chromosome 11 found to be a strong risk locus across European and Chinese ancestries. The findings suggest an increased load of common risk variants in ADHD+DBDs compared to ADHD without DBDs, particularly in association with aggressive behavior.
NATURE COMMUNICATIONS
(2021)
Article
Psychology, Multidisciplinary
Katharina Leo, Sonja Kewitz, Lutz Wartberg, Katajun Lindenberg
Summary: The trajectories of internalizing disorders and behavioral addictions remain largely unknown, with this study focusing on the predictive influence of clinically relevant depression and social anxiety on future Internet use disorder symptoms. Results showed a significant temporal relationship between clinically relevant internalizing disorders and Internet use disorder symptoms at 12-month follow-up. Findings highlight the importance of clinicians paying attention to adolescents with depression and social anxiety who are at increased risk of developing behavioral addictions.
FRONTIERS IN PSYCHOLOGY
(2021)
Article
Psychology, Clinical
Raimondo Maria Pavarin, Francesca Fontana, Monica Pacetti, Samantha Sanchini
Summary: This study investigated individuals with substance use disorders in the metropolitan area of Bologna from 2009 to 2019, and identified a proportion of suicide attempts in this population. The suicide rate was higher than the general population, particularly within one year from the first visit, especially in patients with depression, neurotic and somatoform syndromes, as well as personality and behavioral disorders. The risk was higher in the year 2020 compared to the previous year, but the difference was not significant.
INTERNATIONAL JOURNAL OF MENTAL HEALTH AND ADDICTION
(2022)
Article
Psychiatry
Christoffer Brynte, Lotfi Khemiri, Hannes Stenstrom, Maija Konstenius, Nitya-Jayaram Lindstrom, Johan Franck
Summary: The study found that individuals with both ADHD and AMPH use disorder are more likely to exhibit impulsive behaviors and have deficits in decision-making abilities. Compared to individuals with ADHD alone, those with both ADHD and AMPH use disorder performed worse in impulsive choice tasks. These findings provide evidence for the need of targeted treatment for this comorbid patient group.
Article
Psychiatry
Valdemar Landgren, Elisabeth Fernell, Christopher Gillberg, Magnus Landgren, Mats Johnson
Summary: The study investigated the outcomes in adulthood for children diagnosed with ADHD combined with DCD at a young age. The results showed that individuals with ADHD+DCD had higher rates of psychiatric diagnoses, prescriptions of psychoactive medications, and sick pension occurrence, as well as lower educational attainment and higher welfare recipiency compared to the comparison groups.
Article
Medicine, General & Internal
Alessandro Pallucchini, Marco Carli, Angelo G. I. Maremmani, Marco Scarselli, Giulio Perugi, Icro Maremmani
Summary: The study found that in A-ADHD-SUD patients, the treatment retention rate was the same as in A-ADHD patients without SUD, suggesting that substance use comorbidity does not have an influence on this clinical parameter.
JOURNAL OF CLINICAL MEDICINE
(2021)
Article
Clinical Neurology
Ta-Chuan Yeh, Mu-Hong Chen, Ya-Mei Bai, Shih-Jen Tsai, Ju-Wei Hsu, Kai-Lin Huang, Tung-Ping Su, Tzeng-Ji Chen, Chih-Sung Liang
Summary: This large-scale longitudinal study using the Taiwan National Health Insurance Research Database found that children and adolescents with ASD are more likely to be diagnosed with anxiety disorder in late childhood, and with schizophrenia, bipolar disorder, depressive disorder, and OCD in adolescence.
JOURNAL OF AFFECTIVE DISORDERS
(2023)
Article
Psychology, Developmental
Mao-Hsiu Hua, Kai-Lin Huang, Ju-Wei Hsu, Ya-Mei Bai, Tung-Ping Su, Shih-Jen Tsai, Cheng-Ta Li, Wei-Chen Lin, Tzeng-Ji Chen, Mu-Hong Chen
Summary: The study revealed that adolescents with ADHD were more likely to experience pregnancy and early pregnancy compared to their counterparts without ADHD. Long-term use of ADHD medication was associated with a decreased risk of subsequent early pregnancy.
JOURNAL OF ATTENTION DISORDERS
(2021)
Article
Medicine, General & Internal
Vincenza Spera, Alessandro Pallucchini, Marco Carli, Marco Maiello, Angelo G. Maremmani, Giulio Perugi, Icro Maremmani
Summary: The study compared demographic, clinical, and symptomatologic features between Dual Disorder A-ADHD (DD/A-ADHD) patients and those without dual disorders (NDD/A-ADHD). Results showed that NDD patients were more likely diagnosed with inattentive ADHD subtype, while DD/A-ADHD patients displayed more severe symptoms of hyperactivity/impulsivity. Type 1 and Type 2 substance use patterns had different effects on A-ADHD patients, leading to varied implications in diagnostic and therapeutic processes.
JOURNAL OF CLINICAL MEDICINE
(2021)
Article
Psychiatry
Rahim Badrfam, Atefeh Zandifar, Mahdi Barkhori Mehni, Malihe Farid, Fatemeh Rahiminejad
Summary: The study found a high prevalence of adult ADHD and substance use disorder comorbidity among bipolar disorder patients, with a significant association between adult ADHD and earlier onset of mood episodes in bipolar disorder. Further multicenter studies with larger sample sizes are needed to increase awareness of this comorbidity in hospital settings.
Article
Substance Abuse
Shelley A. Gresko, Maya Rieselbach, Robin P. Corley, Christian J. Hopfer, Michael C. Stallings, John K. Hewitt, Soo Hyun Rhee
Summary: This study examined the association between subjective effects (SEs) and substance use disorders (SUDs) in a clinical sample. The results showed that SEs predicted general and substance-specific SUDs in adolescence and adulthood, and also predicted changes in SUD severity. The study found no racial/ethnic differences in these associations.
DRUG AND ALCOHOL DEPENDENCE
(2023)
Article
Clinical Neurology
Allan Hvolby, Jakob Christensen, Christiane Gasse, Soren Dalsgaard, Julie Werenberg Dreier
Summary: This study found that children and adolescents with ADHD, ASD, and ODD/CD were at higher risk of sleep problems, with females more likely to experience sleep issues than males. Additionally, individuals with these neurodevelopmental disorders had a significantly increased likelihood of sleep problems compared to those without the disorders.
JOURNAL OF SLEEP RESEARCH
(2021)