Article
Medicine, General & Internal
Annegret Hella Dahlmann-Noor, John A. Greenwood, Andrew Skilton, Daniel Baker, Siobhan Ludden, Amanda Davis, Hakim-Moulay Dehbi, Steven C. Dakin
Summary: Current treatments for amblyopia in children often have suboptimal results. In order to address this, a new treatment method called balanced binocular viewing (BBV) using movies has been developed. BBV aims to improve adherence in children and rebalance input from the two eyes. A feasibility trial is needed to test the safety and efficacy of BBV.
Article
Medicine, General & Internal
Hui Huang, Jing Wang, Haoran Li, Ruxue Lei, Weiwen Zou, Qun Huang, Na Gao, Yanlin Zheng
Summary: This study aims to compare the efficacy and safety of acupuncture versus sham acupuncture in treating retinitis pigmentosa. 64 eligible patients will be randomly divided into two groups for a 48-session treatment over 3 months, with follow-up assessments at month 6/9. The primary outcome measures include visual field mean sensitivity and visual field mean deviation, while secondary outcomes include other visual indicators.
Article
Medicine, General & Internal
Navid Farassat, Daniel Boehringer, Sebastian Kuechlin, Fanni E. Molnar, Anne Schwietering, Dorina Seger, Martin J. Hug, Anja-Birte Knoebel, Sabine Schneider-Fuchs, Gabriele Ihorst, Bettina Wabbels, Christina Beisse, Focke Ziemssen, Frank Schuettauf, Andrea Hedergott, Theresia Ring-Mangold, Claudia Schuart, Armin Wolf, Stefanie Schmickler, Julia Biermann, Philipp Eberwein, Karsten Hufendiek, Anja Eckstein, Gabriele Gusek-Schneider, Michael Schittkowski, Thomas Lischka, Wolf A. Lagreze
Summary: The AIM study aims to test the efficacy and safety of 0.02% atropine compared to placebo in controlling myopia in Caucasian children. The study will be divided into three phases, including observation of age, visual changes, and axial length changes. The results of the study will be disseminated through peer-reviewed publications and conference presentations.
Article
Medicine, General & Internal
Alicia Pareja-Rios, Sabato Ceruso, Pedro Romero-Aroca, Sergio Bonaque-Gonzalez
Summary: This study reports the development of a deep learning algorithm (AI) that can accurately detect signs of diabetic retinopathy (DR) from fundus images. The algorithm shows comparable performance to doctors in determining the presence of DR.
JOURNAL OF CLINICAL MEDICINE
(2022)
Article
Medicine, General & Internal
Gen Miura, Yoshihito Ozawa, Yuki Shiko, Yohei Kawasaki, Takayuki Iwase, Tadami Fujiwara, Takayuki Baba, Hideki Hanaoka, Shuichi Yamamoto
Summary: This study is a clinical trial aimed at evaluating the safety and efficacy of transdermal electrical stimulation therapy in patients with retinitis pigmentosa. The study uses multiple measures to assess the treatment outcomes and plans to recruit 50 patients from three Japanese institutions for a one-year follow-up.
Article
Engineering, Biomedical
Bin Duan, Linfei Xiong, Xiaolong Guan, Yongqing Fu, Yongwei Zhang
Summary: Ultrasound scanning is a commonly used diagnostic method with limited access to experienced doctors in rural areas. To address this issue, a remote robotic ultrasound scanning system is introduced, allowing doctors to control the robotic arm and ultrasound machine remotely for diagnosis in remote areas.
BIOMEDICAL SIGNAL PROCESSING AND CONTROL
(2021)
Article
Engineering, Multidisciplinary
Ying Du, Hongkun Wu, David Garcia Cava
Summary: Unmanned aerial vehicles have emerged as a promising method for surface damage detection in wind turbine blades, aiming to reduce cost and downtimes. To tackle the degradation issue caused by motion-blur in captured blade images, an area-based deblurring method is proposed. It involves region division, point spread function estimation, Wiener filter algorithm and image fusion, which effectively mitigates blurring effects and improves the detection accuracy for on-line inspection.
Article
Rehabilitation
Deirdre R. Dawson, Nicole D. Anderson, Malcolm Binns, Yael Bar, Adora Chui, Natasha Gill, Elizabeth Linkewich, Sara McEwen, Emily Nalder, Elizabeth Skidmore
Summary: Long-term limitations in social participation after stroke can be attenuated through tele-rehabilitation, with transfer of learning effects observed. The feasibility and acceptability of tele-CO-OP are high, showing significant improvements in social participation and mood for participants.
DISABILITY AND REHABILITATION
(2022)
Article
Engineering, Multidisciplinary
Filippo Attivissimo, Vito Ivano D'Alessandro, Attilio Di Nisio, Giuliano Scarcelli, Justin Schumacher, Anna Maria Lucia Lanzolla
Summary: This paper examines eye blinking as a means to determine the state of the eyes, analyzing and comparing the performance of five video-based blink algorithms. The results show that the proposed techniques are successful in detecting eye blinks.
Review
Cell Biology
Yinxu Bian, Tao Xing, Kerong Jiao, Qingqing Kong, Jiaxiong Wang, Xiaofei Yang, Shenmin Yang, Yannan Jiang, Renbing Shen, Hua Shen, Cuifang Kuang
Summary: As the demand for bio-medical mobile workstations increases, there is a growing need for lightweight, low-cost microscopic imaging devices. High-performance computational portable microscopes with small sizes and low prices are suitable for fast, timely, and large-scale deployment.
Article
Health Care Sciences & Services
Afsane Riazi, Trefor Aspden, Gary Rubin, Gareth Ambler, Fatima Jichi, Laurence Mynors-Wallice, Miriam O'Driscoll, Kate Walters
Summary: Based on a pilot parallel-group randomized controlled trial, this study found that Problem-Solving Treatment (PST) was associated with a significant and sustained improvement in psychological well-being for people with recent vision loss. The improvements were observed in various outcome measures, including mental well-being level, distress symptoms, quality of life, and self-efficacy.
JOURNAL OF PERSONALIZED MEDICINE
(2022)
Article
Health Care Sciences & Services
Jeewoo Yoon, Jinyoung Han, Junseo Ko, Seong Choi, Ji In Park, Joon Seo Hwang, Jeong Mo Han, Daniel Duck-Jin Hwang
Summary: This study proposes an artificial intelligence-based computer-aided diagnosis system for diagnosing retinal diseases using optical coherence tomography (OCT) images in ophthalmology. Through observer performance tests and evaluation of the deep learning algorithm, the system outperforms ophthalmologists in diagnosing central serous chorioretinopathy (CSC). Especially with the assistance of AI, nonretina specialists can achieve expert-level diagnostic performance.
JOURNAL OF MEDICAL INTERNET RESEARCH
(2023)
Review
Medicine, General & Internal
Grayson W. Armstrong, John B. Miller
Summary: The use of ophthalmic telemedicine for patients with age-related macular degeneration has made significant progress in recent years. It has become even more important during the COVID pandemic, as it provides a safer alternative for evaluating high-risk elderly patients and has shown early successes in home-based remote monitoring.
JOURNAL OF CLINICAL MEDICINE
(2022)
Article
Medicine, General & Internal
Oliver Rajesh Marmoy, Emma Hodson-Tole, Dorothy Ann Thompson
Summary: This project aims to evaluate the PhNR in detecting and monitoring pediatric rICP. The study includes a cross-sectional study and a longitudinal study, assessing the relationship between the PhNR and directly recorded intracranial pressure measurements through regression analysis. The research aims to determine clinically relevant cut-off values and calculate diagnostic accuracy.
Article
Neurosciences
James W. Roberts, Simon J. Bennett
Summary: This study found that aiming accuracy and precision are higher under blurred vision conditions, indicating the importance of online visual feedback for target-directed aiming.
HUMAN MOVEMENT SCIENCE
(2022)
Article
Ophthalmology
Ankush Kawali, Padmamalini Mahendradas, Srinivasan Sanjay, Ashwin Mohan, Bhujang Shetty
Summary: The presence or absence of a positive Weil Felix Test did not significantly impact the clinical manifestations and disease outcomes in Epidemic Retinitis patients. Resolution times for macular edema and retinitis did not differ significantly between the two groups.
OCULAR IMMUNOLOGY AND INFLAMMATION
(2022)
Article
Ophthalmology
Sai Bhakti Mishra, Padmamalini Mahendradas, Ankush Kawali, Srinivasan Sanjay, Rohit Shetty
Summary: This article presents a rare case of varicella zoster infection following COVID-19 vaccination in an elderly Asian Indian male. The findings suggest a possible link between COVID-19 vaccine and viral reactivation, particularly in elderly individuals with comorbidities.
EUROPEAN JOURNAL OF OPHTHALMOLOGY
(2023)
Article
Ophthalmology
Ankush Kawali, Sanjay Srinivasan, Padmamalini Mahendradas, Rohit Shetty
Summary: Treatment of inflammatory macular edema post endophthalmitis is challenging, with risks associated with steroids and anti-VEGF therapy. A 34-year-old Asian Indian woman with traumatic endophthalmitis and recurrent macular edema was successfully treated with topical interferon therapy, showing resolution of edema after 2 months and recurrence responding well to interferon monotherapy during COVID-lock down. Topical interferon may be a safer, economical, and non-invasive treatment option for such cases.
EUROPEAN JOURNAL OF OPHTHALMOLOGY
(2022)
Article
Ophthalmology
Padmamalini Mahendradas, Prathibha Hande, Aditya Patil, Ankush Kawali, Srinivasan Sanjay, Syed Asrar Ahmed, Sherina Thomas, Rohit Shetty
Summary: This case report presents a patient with bilateral multifocal retinitis and multiple vascular occlusions three weeks after a febrile illness, which was managed with systemic steroids, doxycycline, and anticoagulants leading to improvement in vision. High seropositive response against SARS-CoV-2 was identified as the causative agent, but the cross-reactivity of SARS-CoV-2 with other viruses poses a challenge for interpretation.
OCULAR IMMUNOLOGY AND INFLAMMATION
(2022)
Article
Ophthalmology
Srinivasan Sanjay, Seo Wei Leo, Kah - Guan Au Eong, Gitalisa Andayani Adriono, Kenneth C. S. Fong, Kartik Anand, Rumita S. Kadarisman, David B. Granet, Padmamalini Mahendradas, Rohit Shetty, Sharon D. Souza, Swaminathan P. Iyer
Summary: Global ophthalmologists have experienced significant changes in practice patterns during the COVID-19 pandemic, with a precipitous drop in surgical procedures. 41% of ophthalmologists are considering resuming elective surgeries after evaluating the situation. More than 2/3 of respondents prioritize physical distancing, mask-wearing, and hand disinfection for patient protection.
OPHTHALMIC EPIDEMIOLOGY
(2022)
Letter
Ophthalmology
Srinivasan Sanjay, Ankush Kawali, Padmamalini Mahendradas
INDIAN JOURNAL OF OPHTHALMOLOGY
(2022)
Letter
Ophthalmology
Srinivasan Sanjay, Ankush Kawali
INDIAN JOURNAL OF OPHTHALMOLOGY
(2022)
Letter
Ophthalmology
Srinivasan Sanjay, Sai Bhakti Mistra, Sithun Kumar Patro, Ankush Kawali, Rohit Shetty, Padmamalini Mahendradas
Summary: This retrospective case series explored the systemic status in ophthalmic patients with a recent history of COVID-19 or positive COVID-19 antibody status. The study found that serum D-dimer and ferritin levels were significantly elevated in patients with sight threatening ocular manifestations. Furthermore, ESR and CRP remained elevated even after recovery from COVID-19, although the differences were not statistically significant.
OCULAR IMMUNOLOGY AND INFLAMMATION
(2022)
Letter
Ophthalmology
Rohini Sangoram, Padmamalini Mahendradas, Sai Bhakti Mishra, Ankush Kawali, Srinivasan Sanjay, Rohit Shetty
Summary: This case report describes an incidence of HSV 1 anterior uveitis following COVID-19 vaccination. A viral etiology should be considered when ocular symptoms occur after vaccination.
OCULAR IMMUNOLOGY AND INFLAMMATION
(2022)
Letter
Ophthalmology
Ankush Kawali, Srinivasan Sanjay, Padmamalini Mahendradas, Rohit Shetty
Summary: During the COVID-19 pandemic, there have been reports of a known uveitic entity being associated with SARS-CoV-2, but causality has not been proven. If manifestations resembling a region-specific endemic disease occur in a non-endemic country during the pandemic, it may suggest SARS-CoV-2 as a causative organism.
OCULAR IMMUNOLOGY AND INFLAMMATION
(2023)
Article
Ophthalmology
Padmamalini Mahendradas, Sai Bhakti Mishra, Rubble Mangla, Srinivasan Sanjay, Ankush Kawali, Rohit Shetty, Balebail Dharmanand
Summary: This case report highlights the potential risk of exacerbation of uveitis with posterior segment manifestations following anti-SARS-CoV-2 vaccination in patients with JIA-associated uveitis.
JOURNAL OF OPHTHALMIC INFLAMMATION AND INFECTION
(2022)
Letter
Ophthalmology
Ankush Kawali, Srinivasan Sanjay, Padmamalini Mahendradas, Bhujang Shetty
Summary: The characteristics and course of known seasonal diseases may or may not change during the COVID-19 pandemic. It is debatable whether COVID-19 should be labeled as a novel cause of these seasonal diseases or considered as a coinfection. Further investigations are necessary to rule out previously known causes and correlate them with COVID-19.
OCULAR IMMUNOLOGY AND INFLAMMATION
(2023)
Article
Ophthalmology
Ankush Kawali, Sujani Shroff, Srinivasan Sanjay, Sai Bhakti Mishra, Ashwin Mohan, Padmamalini Mahendradas, Rohit Shetty
Summary: This study analyzed visual field defects (VFDs) in patients with epidemic retinitis (ER). The findings showed that ER can cause persistent VFDs even after resolution, and treatment with oral doxycycline without steroids was found to be non-inferior to combined treatment.
OCULAR IMMUNOLOGY AND INFLAMMATION
(2023)
Article
Ophthalmology
Srinivasan Sanjay, Ashit Handa, Ankush Kawali, Rohit Shetty, Sai Bhakti Mishra, Padmamalini Mahendradas
Summary: This study reported cases of scleritis and episcleritis occurring within a month after COVID-19 vaccination. A total of 15 eyes from 12 patients were included. The mean time of symptom onset was 15.7 days for scleritis and 13.2 days for episcleritis. Treatment included topical steroids and systemic COX2 inhibitors. Scleritis and episcleritis following COVID-19 vaccination are usually mild and do not typically require intensive immunosuppression.
OCULAR IMMUNOLOGY AND INFLAMMATION
(2023)
Article
Ophthalmology
Padmamalini Mahendradas, Swaminathan Sethu, Chaitra Jayadev, Aaditi Anilkumar, Ankush Kawali, Srinivasan Sanjay, Sai Bhakti Mishra, Rohit Shetty, Bhujang K. Shetty
Summary: The purpose of this study was to examine the use of teleophthalmology for managing uveitis patients and to describe the experience of teleconsultation for uveitis at a tertiary eye care hospital in India during the COVID-19 pandemic. The results showed that teleconsultation using a customized smartphone-based application could provide alternative ophthalmic care for uveitis patients and help reduce hospital visits during the pandemic.
INDIAN JOURNAL OF OPHTHALMOLOGY
(2022)
