Article
Medicine, General & Internal
Deborah Schofield, Joshua Kraindler, Owen Tan, Rupendra N. Shrestha, Sarah West, Natalie Hart, Liny Tan, Alan Ma, John R. Grigg, Robyn Jamieson
Summary: This study estimated the healthcare and societal costs of inherited retinal diseases (IRDs) in Australia. The total estimated lifetime cost per person with an IRD was $5.2 million, with 87% being societal costs and 13% healthcare costs. The highest cost items were lost income, both for individuals with IRDs and their carers and spouses.
MEDICAL JOURNAL OF AUSTRALIA
(2023)
Review
Medicine, General & Internal
Varshanie Jeevakumar, Rebekah Sefton, Joyce Chan, Bamini Gopinath, Gerald Liew, Tejal M. Shah, Joyce Siette
Summary: This systematic review examines the association between retinal markers and cognitive impairment in adults aged 65 years and over. Optical coherence tomography (OCT) is the most commonly used retinal scanning methodology. Results suggest that retinal nerve fibre layer thickness is linked with cognitive performance and may be a potential tool for detecting cognitive impairment in older adults. Further longitudinal studies are needed to validate the findings and understand the underlying mechanisms before implementing OCT as a dementia screening tool.
Review
Chemistry, Multidisciplinary
Sam Yu, Vasudevan Lakshminarayanan
Summary: The review summarizes the relationship between fractal dimension and retinal pathology from 28 studies analyzed via meta-analysis. The results suggest decreased retinal fractal dimension for diabetic retinopathy and myopia, while the associations with other diseases like diabetes mellitus, hypertension, and glaucoma remain uncertain. Standardized retinal fractal analysis procedures are recommended for future meta-analyses due to heterogeneity in imaging setups used across studies.
APPLIED SCIENCES-BASEL
(2021)
Article
Computer Science, Artificial Intelligence
Shuhe Zhang, Ashwin Mohan, Carroll A. B. Webers, Tos T. J. M. Berendschot
Summary: In this research, a duality between cataractous retinal image dehazing and image denoising was studied. The study proposed a method that combines image denoising and sigmoid function to achieve dehazing of cataractous retinal images. The method employs a double-pass fundus reflection model in the YPbPr color space and a multilevel stimulated denoising strategy. The proposed method was tested and compared with other enhancement methods, showing superior performance. The study also demonstrated potential applications in blood vessel segmentation, retinal image registrations, and diagnosing with enhanced images.
MEDICAL IMAGE ANALYSIS
(2023)
Article
Computer Science, Artificial Intelligence
Clement Playout, Renaud Duval, Marie Carole Boucher, Farida Cheriet
Summary: This study provides a thorough evaluation of multiple Transformer models for retinal disease classification, with a focus on multi-modality imaging and generalization to external data. It also proposes an improved mechanism for generating interpretable predictions.
MEDICAL IMAGE ANALYSIS
(2022)
Review
Clinical Neurology
Carol Y. Cheung, Vincent Mok, Paul J. Foster, Emanuele Trucco, Christopher Chen, Tien Yin Wong
Summary: Retinal imaging technologies play a crucial role in studying Alzheimer's disease, with qualitative and quantitative measurements associated with cognitive impairment and AD risk. Development of computer algorithms enhances the potential of retinal imaging for early detection and screening of AD.
JOURNAL OF NEUROLOGY NEUROSURGERY AND PSYCHIATRY
(2021)
Article
Medicine, General & Internal
Reinhard Angermann, Anna Lena Huber, Markus Hofer, Yvonne Nowosielski, Stefan Egger, Martina T. Kralinger, Claus Zehetner
Summary: The study found that factors affecting OR time efficiency in the surgical management of primary RRD include giant tear, PVR-C, surgery delayed for 72 hours, GA, and surgery performed by a trainee. In addition, PVR in PPV cases, after-hours settings, and surgeon experience in SB cases are independent risk factors for reduced success rates.
Article
Health Care Sciences & Services
Earnest P. Chen, Michael Mills, Tara Gallagher, Andrew Polis, Sophie Blasberg, Peter Pham, Ronald C. Gentile, Tsontcho Ianchulev
Summary: This study evaluates the effectiveness of the Accustat (R) test in remote monitoring of visual function. The results show a high correlation between the Accustat test and the office Snellen test, indicating the potential utility of scalable remote monitoring of central retinal function via telehealth.
Letter
Ophthalmology
Julio J. Gonzalez-Lopez, Beatriz Felix Espinar, Cristina Ye-Zhu
Summary: COVID-19 can cause eye complications, such as conjunctivitis and retinal microvascular ischemia. This case report describes bilateral retinal microangiopathy occurring during the late phase of COVID-19, leading to visual field defects.
OCULAR IMMUNOLOGY AND INFLAMMATION
(2021)
Article
Medicine, General & Internal
Ahmed Mahdy, Martin Stradner, Andreas Roessler, Bianca Brix, Angelika Lackner, Adam Salon, Nandu Goswami
Summary: This case-control study found a high prevalence of hypertension and signs of endothelial dysfunction in patients with autoimmune rheumatic diseases, which are important contributing risk factors for cardiovascular diseases.
JOURNAL OF CLINICAL MEDICINE
(2021)
Review
Pharmacology & Pharmacy
Walter H. Moos, Douglas V. Faller, Ioannis P. Glavas, David N. Harpp, Natalia Kamperi, Iphigenia Kanara, Krishna Kodukula, Anastasios N. Mavrakis, Julie Pernokas, Mark Pernokas, Carl A. Pinkert, Whitney R. Powers, Konstantina Sampani, Kosta Steliou, Constantin Tamvakopoulos, Demetrios G. Vavvas, Robert J. Zamboni, Xiaohong Chen
Summary: Pathological deterioration of mitochondrial function is increasingly linked with degenerative illnesses, including genetic diseases. Vision impairment due to mitochondrial dysfunction is common in ophthalmic disorders, and alpha-lipoyl-L-carnitine has potential in treating eye diseases.
BIOCHEMICAL PHARMACOLOGY
(2022)
Review
Ophthalmology
Sepehr Feizi, Mohammadhasan Alemzadeh-Ansari, Farid Karimian, Hamed Esfandiari
Summary: This article investigates the biological roles of erythropoietin (EPO) in the development and normal functions of the eye and its applications in managing various ocular diseases.
SURVEY OF OPHTHALMOLOGY
(2022)
Article
Engineering, Electrical & Electronic
Shuhe Zhang, Carroll A. B. Webers, Tos T. J. M. Berendschot
Summary: This study introduces a novel double pass fundus reflection (DPFR) model for retinal image enhancement, showcasing its superiority in restoration quality and implementation efficiency through experimental validation.
Review
Medicine, General & Internal
Paul McCann, Zanna Kruoch, Riaz Qureshi, Tianjing Li
Summary: Dry eye is a common condition that creates a significant burden on patients and healthcare systems. This study aims to provide guidance on interventions for dry eye by collecting and synthesizing evidence from relevant systematic reviews. The study is scheduled to start in May 2021 and end in April 2022, with the results to be published in a peer-reviewed journal.
Article
Health Care Sciences & Services
Betty A. Situ, Hong-Uyen Hua, Abdul-Hadi Kaakour, Lauren Patty Daskivich, Stavros Savvas, Brian C. Toy
Summary: This study compared teleretinal screening with face-to-face screening and found that teleretinal screening can significantly improve clinical efficiency, reduce wait times, and increase adherence to recommended screening guidelines.
JOURNAL OF TELEMEDICINE AND TELECARE
(2023)
Review
Ophthalmology
Andrea Russo, Francesco Morescalchi, Simone Donati, Elena Gambicorti, Claudio Azzolini, Ciro Costagliola, Francesco Semeraro
INTERNATIONAL OPHTHALMOLOGY
(2018)
Article
Ophthalmology
Paolo Vinciguerra, Fabrizio I. Camesasca, Emanuela Morenghi, Claudio Azzolini, Luca Pagano, Silvia Trazza, Riccardo Vinciguerra
JOURNAL OF REFRACTIVE SURGERY
(2018)
Review
Ophthalmology
Raffaele Nuzzi, Federico Tridico
JOURNAL OF OPHTHALMOLOGY
(2019)
Review
Ophthalmology
Chiara De Giacinto, Marco R. Pastore, Gabriella Cirigliano, Daniele Tognetto
JOURNAL OF OPHTHALMOLOGY
(2019)
Review
Ophthalmology
Greg Budoff, Neelakshi Bhagat, Marco A. Zarbin
JOURNAL OF OPHTHALMOLOGY
(2019)
Article
Ophthalmology
Simone Donati, Paola Della Valle, Elias Premi, Marco Mazzola, Laura Lo Presti, Claudio Azzolini
JOURNAL OF OPHTHALMOLOGY
(2019)
Article
Ophthalmology
Federico Peralta Iturburu, Claudia Garcia-Arumi, Maria Bove Alvarez, Jose Garcia-Arumi
JOURNAL OF OPHTHALMOLOGY
(2019)
Review
Ophthalmology
Qi Chen, Zao-xia Liu
JOURNAL OF OPHTHALMOLOGY
(2019)
Article
Clinical Neurology
Paolo Castelnuovo, Alberto D. Arosio, Luca Volpi, Federico De Maria, Arianna Ravasio, Simone Donati, Claudio Azzolini, Iacopo Dallan, Maurizio Bignami, Davide Locatelli
WORLD NEUROSURGERY
(2019)
Article
Ophthalmology
Rino Frisina, Francesco Tessarolo, Ivan Marchesoni, Federico Piccoli, Emiliana Bonomi, Patrizio Caciagli, Edoardo Midena, Giandomenico Nollo
JOURNAL OF OPHTHALMOLOGY
(2019)
Article
Ophthalmology
Simone Donati, Andrea Maria Maresca, Jennifer Cattaneo, Alessandra Grossi, Marco Mazzola, Simona Maria Caprani, Laura Premoli, Franco Docchio, Damiano Rizzoni, Luigina Guasti, Claudio Azzolini
Summary: The study utilized optical coherence tomography angiography to evaluate retinal microvasculature changes in hypertensive patients, revealing significant differences in vascular density and choroidal thickness compared to healthy subjects. These findings highlight the potential of OCTA in identifying early pathological markers of hypertensive damage and monitoring disease progression.
EUROPEAN JOURNAL OF OPHTHALMOLOGY
(2021)
Editorial Material
Ophthalmology
Claudio Azzolini
JOURNAL OF OPHTHALMOLOGY
(2020)
Review
Ophthalmology
Cristian Metrangolo, Simone Donati, Marco Mazzola, Liviana Fontanel, Walter Messina, Giulia D'alterio, Marisa Rubino, Paolo Radice, Elias Premi, Claudio Azzolini
Summary: This review article discusses the importance and application of structural OCT-based biomarkers in the initial assessment and treatment follow-up of nAMD patients, providing valuable tools for monitoring disease progression and treatment response.
JOURNAL OF OPHTHALMOLOGY
(2021)
Article
Ophthalmology
Claudio Azzolini, Simone Donati, Giovanni Micheloni, Vittoria Moretti, Roberto Valli, Francesco Acquati, Lucy Costantino, Fulvio Ferrara, Davide Borroni, Elias Premi, Francesco Testa, Francesca Simonelli, Giovanni Porta
Summary: The study evaluated the effects of simulating hypoxic stimulus on a set of genes related to eye morphogenesis and cell differentiation. Results showed that while Otx1 and Otx2 did not show significant changes in expression levels during treatment, VEGF-A and TP73 genes were significantly regulated during both the hypoxic stimulus and recovery stages.
JOURNAL OF OPHTHALMOLOGY
(2021)
Review
Ophthalmology
Elias Premi, Simone Donati, Lorenzo Azzi, Giovanni Porta, Cristian Metrangolo, Liviana Fontanel, Francesco Morescalchi, Claudio Azzolini
Summary: Macular holes are a spectrum of retinal diseases with different subtypes and treatment approaches. Recent advancements in retinal imaging have allowed researchers to define a common nomenclature for these conditions.
JOURNAL OF OPHTHALMOLOGY
(2022)