Molecular Transformation via Nickelacycle Intermediate

Nickelacycles have been known as a key reaction intermediate. The beta-hydrogen transfer reactions from nickelacycles allow us to synthesize acyclic organic compounds. The reductive elimination from nickelacycles allows us to synthesize a variety of cyclic organic compounds. Thus, the generation of a new nickelacycles from a new combination of unsaturated compounds and nickel (0) species is a key to develop nickel-catalyzed new reactions. We report here the new molecular transformations of a variety of unsaturated compounds via nickelacycles in which both acyclic and cyclic compounds were obtained. In addition, the isolation of the reaction intermediates and their reaction mechanisms are discussed as well.