Article
Radiology, Nuclear Medicine & Medical Imaging
Josua A. A. Decker, Jim O'Doherty, U. Joseph Schoepf, Thomas M. M. Todoran, Gilberto J. J. Aquino, Verena Brandt, Dhiraj Baruah, Nicola Fink, Emese Zsarnoczay, Thomas Flohr, Bernhard Schmidt, Thomas Allmendinger, Franka Risch, Akos Varga-Szemes, Tilman Emrich
Summary: This study assessed the impact of scan modes and reconstruction kernels using a novel dual-source photon-counting detector CT (PCD-CT) on the lumen visibility and sharpness of different stent sizes. The results showed that the UHR acquisition mode and sharp reconstruction kernels significantly improved the in-stent lumen visibility and sharpness, especially for smaller stent sizes.
EUROPEAN RADIOLOGY
(2023)
Article
Chemistry, Multidisciplinary
Benedicta D. Arhatari, Andrew W. Stevenson, Darren Thompson, Adam Walsh, Tom Fiala, Gary Ruben, Nader Afshar, Sinem Ozbilgen, Tingting Feng, Stephen Mudie, Prithi Tissa
Summary: The Micro-Computed Tomography (MCT) beamline, the first one in the BRIGHT project, has been constructed at the Australian Synchrotron to provide higher spatial resolution imaging for smaller samples compared to the existing Imaging and Medical Beamline (IMBL). This beamline operates with an X-ray energy range from 8 to 40 keV using a bending magnet as the source. It offers various imaging modes including phase-contrast modalities and conventional absorption contrast, leveraging the unique properties of synchrotron radiation sources. The progress and imaging results of the MCT project in delivering high-spatial-resolution imaging will be presented in the paper.
APPLIED SCIENCES-BASEL
(2023)
Article
Multidisciplinary Sciences
Hongchang Wang, Kawal Sawhney
Summary: Researchers have successfully generated omnidirectional differential phase images using X-ray differential phase contrast imaging, providing more information for studying complex samples and enabling simultaneous extraction of omnidirectional dark-field images to study ordered scattering structures.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
(2021)
Article
Multidisciplinary Sciences
Hongchang Wang, Kawal Sawhney
Summary: This article introduces a method for generating omnidirectional differential phase images by scanning a randomly structured modulator, which provides more information than traditional imaging methods and allows the simultaneous extraction of omnidirectional dark-field images for studying strongly ordered scattering structures.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
(2021)
Article
Multidisciplinary Sciences
Guibin Zan, Sheraz Gul, Jin Zhang, Wei Zhao, Sylvia Lewis, David J. Vine, Yijin Liu, Piero Pianetta, Wenbing Yun
Summary: The study developed a TLI system with MAAST source, offering high-resolution and tri-contrast X-ray imaging for biomedical applications. Tomography of Drum fish tooth revealed valuable complementary structural information using this method.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
(2021)
Article
Optics
Zhi Qiao, Xianbo Shi, Yudong Yao, Michael J. Wojcik, Luca Rebuffi, Mathew J. Cherukara, Lahsen Assoufid
Summary: By utilizing deep learning, the speckle-based phase-contrast imaging neural network (SPINNet) significantly enhances imaging quality and retrieval speed compared to existing methods. It enables high-resolution and fast data acquisition and processing for various applications.
Article
Food Science & Technology
Masafumi Hidaka, Shuhei Miyashita, Naoto Yagi, Masato Hoshino, Yukiya Kogasaka, Tomoyuki Fujii, Yoshinori Kanayama
Summary: This study conducted X-ray phase-contrast CT imaging on cooked edamame and found that vascular structures and cracks were clearly visible. The fine structure of the seed coat, important for seed development and processing, was also observed. The density of edamame decreased with increasing boiling time, resulting in reduced hardness. The results demonstrate that high-resolution nondestructive X-ray phase-contrast CT imaging can effectively evaluate vegetable quality and observe internal structures related to plant development.
Article
Engineering, Biomedical
Eric Grolman, Quinton E. A. Sirianni, Joy Dunmore-Buyze, Charmainne Cruje, Maria Drangova, Elizabeth R. Gillies
Summary: Medical imaging plays a crucial role in clinical diagnosis and disease research. This article introduces a new self-immolative polymeric chelate system that has a long circulation time in the blood and completely degrades into small molecules for excretion. The successful application of this system in micro-CT demonstrates its promising potential in the development of imaging contrast agents.
ACTA BIOMATERIALIA
(2023)
Article
Physics, Applied
L. Brombal, F. Arfelli, F. Brun, F. Longo, N. Poles, L. Rigon
Summary: Accurate simulation tools are important for the design and optimization of x-ray phase-contrast imaging setups. This study presents a practical implementation of x-ray phase-contrast in Geant4 and validates the simulation results against theoretical predictions.
JOURNAL OF PHYSICS D-APPLIED PHYSICS
(2022)
Article
Computer Science, Interdisciplinary Applications
A. Aminzadeh, B. D. Arhatari, A. Maksimenko, C. J. Hall, D. Hausermann, A. G. Peele, J. Fox, B. Kumar, Z. Prodanovic, M. Dimmock, D. Lockie, K. M. Pavlov, Y. Nesterets, D. Thompson, S. C. Mayo, D. M. Paganin, S. T. Taba, S. Lewis, P. C. Brennan, H. M. Quiney, T. E. Gureyev
Summary: In this study, a method to improve the detection of microcalcifications in breast tissues using propagation-based phase-contrast X-ray computed tomography was proposed. The results showed that the visibility of microcalcifications in the dark-field images was more than two times higher compared to the bright-field images, and the dark-field images provided more accurate information about the size and shape of the microcalcifications.
IEEE TRANSACTIONS ON MEDICAL IMAGING
(2022)
Article
Radiology, Nuclear Medicine & Medical Imaging
Leening P. Liu, Nadav Shapira, Andrew A. Chen, Russell T. Shinohara, Pooyan Sahbaee, Mitchell Schnall, Harold Litt, Peter B. Noel
Summary: This study compared the image characteristics of a first-generation dual-source photon-counting computed tomography (PCCT) and a dual-source dual-energy CT (DECT) scanner at ultra-low radiation dose levels. The results showed that PCCT had high precision in Hounsfield unit (HU) measurements at various radiation dose levels, outperforming DECT at low doses and significantly reducing electronic background noise.
EUROPEAN RADIOLOGY
(2022)
Article
Chemistry, Physical
Julien Gonthier, Tilman Rilling, Ernesto Scoppola, Fabian Zemke, Aleksander Gurlo, Peter Fratzl, Wolfgang Wagermaier
Summary: This study used in operando X-ray micro-computed tomography (mu CT) to monitor the progression of the liquid, gaseous, and solid phases of silica gels during ambient pressure drying and spring-back. The findings challenge the common assumption about the penetration of gas during the spring-back effect and show that the emergence of the spring-back effect is correlated to an equal volume fraction of solid, liquid, and gas in the gels.
CHEMISTRY OF MATERIALS
(2023)
Article
Physics, Multidisciplinary
Darren J. Batey, Frederic Van Assche, Sander Vanheule, Matthieu N. Boone, Andrew J. Parnell, Oleksandr O. Mykhaylyk, Christoph Rau, Silvia Cipiccia
Summary: This experiment demonstrated the successful application of X-ray ptychography in a small-scale laboratory setting, showcasing the potential for high-resolution phase contrast imaging to be performed at small-scale sources worldwide.
PHYSICAL REVIEW LETTERS
(2021)
Article
Optics
K. A. Ivanov, I. M. Gavrilin, R. V. Volkov, S. A. Gavrilov, A. B. Savel'Ev
Summary: The characterization of hard x-ray copper K (alpha) source indicates that using structured copper targets can significantly increase photon flux and conversion efficiency, but the efficient use at higher intensity is limited. The lateral coherence of the x-ray source does not differ between the flat and thicket targets, making it suitable for x-ray phase contrast imaging.
LASER PHYSICS LETTERS
(2021)
Review
Chemistry, Multidisciplinary
Akio Yoneyama, Daiko Takamatsu, Thet-Thet Lwin, Shigehito Yamada, Tetsuya Takakuwa, Kazuyuki Hyodo, Keiichi Hirano, Satoshi Takeya
Summary: Crystal-based X-ray interferometry (CXI) detects X-ray phase shifts with the highest sensitivity among the X-ray phase-detecting methods. Phase-contrast X-ray imaging (PCXI) using CXI has the highest density resolution and has been widely applied in various fields. Novel imaging methods have also been developed to take advantage of CXI's high sensitivity, such as visualization of the effective atomic number and the three-dimensional temperature. This article reviews the principles, history, and potential applications of PCXI and CXI systems.
APPLIED SCIENCES-BASEL
(2023)
Article
Geriatrics & Gerontology
Ahmed Al Saedi, Craig A. Goodman, Damian E. Myers, Alan Hayes, Gustavo Duque
JOURNALS OF GERONTOLOGY SERIES A-BIOLOGICAL SCIENCES AND MEDICAL SCIENCES
(2020)
Article
Radiology, Nuclear Medicine & Medical Imaging
Seyedamir Tavakoli Taba, Benedicta D. Arhatari, Yakov I. Nesterets, Ziba Gadomkar, Sheridan C. Mayo, Darren Thompson, Jane Fox, Beena Kumar, Zdenka Prodanovic, Daniel Hausermann, Anton Maksimenko, Christopher Hall, Matthew Dimmock, Konstantin M. Pavlov, Darren Lockie, Masoumeh Gity, Andrew Peele, Harry M. Quiney, Sarah Lewis, Timur E. Gureyev, Patrick C. Brennan
Summary: This study aimed to optimize the experimental conditions of Propagation-based phase-contrast CT (PB-CT) for breast cancer imaging and found that it achieved higher image quality compared to conventional absorption-based CT (AB-CT) even at lower doses, potentially improving breast cancer diagnosis.
ACADEMIC RADIOLOGY
(2021)
Article
Cardiac & Cardiovascular Systems
Yue Qu, David McGiffin, Christopher Hayward, Janelle McLean, Courtney Duncan, Desiree Robson, Christina Kure, Rong Shen, Helen Williams, Sherry Mayo, Helmut Thissen, Silvana Marasco, Adam Zimmet, Justin Negri, Paul Jansz, Kumud Dhital, David M. Kaye, Anton Y. Peleg
JOURNAL OF HEART AND LUNG TRANSPLANTATION
(2020)
Article
Endocrinology & Metabolism
Ahmed Al Saedi, Damian E. Myers, Nicole Stupka, Gustavo Duque
Article
Chemistry, Multidisciplinary
Benedicta D. Arhatari, Andrew W. Stevenson, Brian Abbey, Yakov I. Nesterets, Anton Maksimenko, Christopher J. Hall, Darren Thompson, Sheridan C. Mayo, Tom Fiala, Harry M. Quiney, Seyedamir T. Taba, Sarah J. Lewis, Patrick C. Brennan, Matthew Dimmock, Daniel Hausermann, Timur E. Gureyev
Summary: IMBL is a beamline at the Australian Synchrotron that delivers hard X-rays for biomedical applications, including propagation-based X-ray phase-contrast computed tomography (PCT) for imaging low-density materials. The unique properties of synchrotron X-ray sources allow for high sensitivity phase-contrast imaging with short exposure times. Ongoing research aims to introduce innovative 3D X-ray medical imaging techniques to improve breast cancer detection and diagnosis.
APPLIED SCIENCES-BASEL
(2021)
Article
Physics, Applied
Jeremy A. Davis, Elette Engels, Marco Petasecca, Jason Paino, Moeava Tehei, Stephanie Corde, Andrew Stevenson, Daniel Hausermann, Susanna Guatelli, Anatoly Rosenfeld, Michael L. F. Lerch
Summary: Recommendations for an experimental protocol for beam alignment/optimization and dosimetry in in vitro studies at the Australian Synchrotron's Imaging and Medical Beam Line are presented, along with an evaluation based on the consistency and reproducibility of in vitro experiments conducted at the facility over several years.
JOURNAL OF APPLIED PHYSICS
(2021)
Article
Radiology, Nuclear Medicine & Medical Imaging
Sarina Wan, Benedicta D. Arhatari, Yakov Nesterets, Sheridan C. Mayo, Darren Thompson, Jane Fox, Beena Kumar, Zdenka Prodanovic, Daniel Hausermann, Anton Maksimenko, Christopher Hall, Matthew Dimmock, Konstantin M. Pavlov, Darren Lockie, Mary Rickard, Ziba Gadomkar, Alaleh Aminzadeh, Elham Vafa, Andrew Peele, Harry M. Quiney, Sarah Lewis, Timur E. Gureyev, Patrick C. Brennan, Seyedamir Tavakoli Taba
Summary: This study investigated the relationship between X-ray energy and image quality in PB-CT imaging, with results showing that images produced at 30 keV had the highest quality, leading to improved contrast and potentially lower breast cancer mortality rates.
JOURNAL OF MEDICAL IMAGING
(2021)
Article
Food Science & Technology
Sumana Chakrabarti-Bell, Jonas Lukasczyk, Jie Liu, Ross Maciejewski, Xianghui Xiao, Sherry Mayo, Klaus Regenauer-Lieb
Summary: Using Synchrotron X-ray tomography, the study investigated how the growth and movement of gas bubbles in leavened and unleavened bread doughs of different flours are affected. It was found that bubbles were mobile in all doughs, with a higher rate of coalescence in leavened doughs. The study also compared the rate of coalescence between Australian Wylkatchem flour dough and Canadian Western Red Spring flour dough.
INNOVATIVE FOOD SCIENCE & EMERGING TECHNOLOGIES
(2021)
Article
Optics
S. J. Alloo, D. M. Paganin, K. S. Morgan, T. E. Gureyev, S. C. Mayo, S. Mohammadi, D. Lockie, R. H. Menk, F. Arfelli, F. Zanconati, G. Tromba, K. M. Pavlov
Summary: Propagation-based phase-contrast x-ray imaging (PB-PCXI) is a useful technique for imaging weakly attenuating samples, providing better contrast than conventional attenuation-based imaging. In this study, a PB-PCXI algorithm is proposed to extract the x-ray attenuation and refraction information of complex materials from an unknown sample, without prior information. The algorithm involves curve fitting an error-function-based model to a phase-retrieved interface, allowing for the calculation of true attenuation and refraction values.
Article
Radiology, Nuclear Medicine & Medical Imaging
Samantha J. Alloo, David M. Paganin, Kaye S. Morgan, Marcus J. Kitchen, Andrew W. Stevenson, Sheridan C. Mayo, Heyang T. Li, Ben M. Kennedy, Anton Maksimenko, Joshua C. Bowden, Konstantin M. Pavlov
Summary: This study investigates the extraction of an object's dark-field signal using intrinsic speckle tracking, demonstrating the ability to tomographically reconstruct the dark-field signal of a wood sample, enhancing phase-contrast reconstructions.
JOURNAL OF MEDICAL IMAGING
(2022)
Article
Computer Science, Interdisciplinary Applications
A. Aminzadeh, B. D. Arhatari, A. Maksimenko, C. J. Hall, D. Hausermann, A. G. Peele, J. Fox, B. Kumar, Z. Prodanovic, M. Dimmock, D. Lockie, K. M. Pavlov, Y. Nesterets, D. Thompson, S. C. Mayo, D. M. Paganin, S. T. Taba, S. Lewis, P. C. Brennan, H. M. Quiney, T. E. Gureyev
Summary: In this study, a method to improve the detection of microcalcifications in breast tissues using propagation-based phase-contrast X-ray computed tomography was proposed. The results showed that the visibility of microcalcifications in the dark-field images was more than two times higher compared to the bright-field images, and the dark-field images provided more accurate information about the size and shape of the microcalcifications.
IEEE TRANSACTIONS ON MEDICAL IMAGING
(2022)
Proceedings Paper
Optics
Belinda Lim, Sarah Lewis, Benedicta D. Arhatari, Yakov Nesterets, Sheridan Mayo, Darren Thomposon, Jane Fox, Beena Kumar, Daniel Hausermann, Anton Maksimenko, Christopher Hall, Matthew Dimmock, Darren Lockie, Mary Rickard, Nicola Giannotti, Andrew Peele, Harry Quiney, Timur E. Gureyev, Patrick Brennan, Seyedamir T. Taba
Summary: This study aims to determine the optimal x-ray energy for PB-CT images of breast mastectomy samples and investigate the correlation between objective physical measures of image quality and subjective human observer scores. The results suggest that 30-34 keV provides optimum image quality for breast PB-CT.
MEDICAL IMAGING 2022: PHYSICS OF MEDICAL IMAGING
(2022)
Proceedings Paper
Optics
S. J. Alloo, D. M. Paganin, K. S. Morgan, M. J. Kitchen, A. W. Stevenson, S. C. Mayo, H. T. Li, B. M. Kennedy, A. Maksimenko, J. Bowden, K. M. Pavlov
Summary: Spatial resolution in standard phase-contrast X-ray imaging is limited by the size and number of detector pixels. Dark-field imaging allows information about unresolved microstructures to be obtained through small-angle X-ray scattering. This paper utilizes speckle-tracking-based X-ray imaging to extract effective dark-field signal from a wood sample.
DEVELOPMENTS IN X-RAY TOMOGRAPHY XIII
(2021)
Proceedings Paper
Optics
Benedicta D. Arhatari, Yakov Nesterets, Seyedamir T. Taba, Anton Maksimenko, Christopher J. Hall, Andrew W. Stevenson, Daniel Hausermann, Sarah J. Lewis, Matthew Dimmock, Darren Thompson, Sheridan C. Mayo, Harry M. Quiney, Timur E. Gureyev, Patrick C. Brennan
Summary: The PB-CT technique utilizes high coherence and brightness of synchrotron X-ray sources, improving sensitivity to small density differences in soft tissues and tumors. It is expected to reduce radiation dose and enhance detection and diagnosis of breast cancer.
DEVELOPMENTS IN X-RAY TOMOGRAPHY XIII
(2021)
