期刊
JOURNAL OF SULFUR CHEMISTRY
卷 36, 期 1, 页码 1-8出版社
TAYLOR & FRANCIS LTD
DOI: 10.1080/17415993.2014.963580
关键词
chronopotentiometry; cyclic voltammetry; chronocoulometry; acetaminophen poisoning; garlic extract
资金
- Bu-Ali Sina University Research Council
- Center of Excellence in Development of Environmentally Friendly Methods for Chemical Synthesis (CEDEFMCS)
The electrochemical oxidation of N-acetyl-p-aminophenol (acetaminophen) (AC) has been studied in the presence of garlic and onion extracts using cyclic voltammetry, chronopotentiometry and chronocoulometry methods. The results revealed that the electrochemically generated toxic N-acetyl-p-benzoquinone-imine participates in the Michael addition reaction with organosulfur compounds contained in garlic or onion extracts and is converted to its reduced none toxic form(s). Based on these results, garlic and onion extracts can be useful for the treatment of acetaminophen poisoning before starting clinical treatments.
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