Article
Clinical Neurology
Jinlei Li, Chunyu Liu, Ting Fang Alvin Ang, Rhoda Au
Summary: This study found that decreasing BMI trends in late life were associated with higher risk of developing dementia. Among them, individuals with an initial increase and subsequent decline in BMI during mid-life had a greater risk of dementia.
ALZHEIMERS & DEMENTIA
(2022)
Article
Multidisciplinary Sciences
Mi Kyoung Son, Dae Sub Song, Kyoungho Lee, Hyun-Young Park
Summary: This study aimed to identify modifiable risk factors for atrial fibrillation (AF) in the midlife general population and estimate their impact. The results showed that high systolic blood pressure, obesity with central obesity, and an inactive lifestyle were significantly associated with incident AF. Maintaining or achieving a lower burden of modifiable risk factors was associated with decreased AF risk.
SCIENTIFIC REPORTS
(2022)
Article
Public, Environmental & Occupational Health
Jinlei Li, Prajakta Joshi, Ting Fang Alvin Ang, Chunyu Liu, Sanford Auerbach, Sherral Devine, Rhoda Au
Summary: This study found a complex relationship between BMI and dementia risk, with the association potentially showing different patterns as individuals age. Monitoring BMI at different ages could help mitigate the risk of dementia over a person's lifetime.
AMERICAN JOURNAL OF EPIDEMIOLOGY
(2021)
Article
Nutrition & Dietetics
Hans Demmelmair, Manja Fleddermann, Berthold Koletzko
Summary: This study examined the long-term effects of different infant feeding choices on growth measures until the age of seven. The results showed that the three study groups did not differ in their anthropometric measures, but the IGF-1 serum concentrations at four months were associated with weight, height, and BMI at the age of seven. The findings suggest that diet-induced modulation of IGF-1 in the first months of life may have lasting programming effects on later growth.
Article
Nutrition & Dietetics
Tsung Yu, Yacong Bo, Ly-Yun Chang, Xudong Liu, Tony Tam, Xiang Qian Lao
Summary: This study found that BMI remains the primary marker for screening excessive adiposity in assessing the risk of mortality. However, waist circumference, waist-to-height ratio, and body fat percentage can also be valuable additional indicators in the evaluation of mortality risk.
CLINICAL NUTRITION
(2021)
Article
Public, Environmental & Occupational Health
Guoyang Qin, Hui Li, Yong Qin, Bin Liu
Summary: The study revealed that the COVID-19 epidemic affected the BMI and obesity detection rate of adolescents, with adolescents from different age groups and genders showing similar development trends.
FRONTIERS IN PUBLIC HEALTH
(2023)
Review
Nutrition & Dietetics
Magali Rios-Leyvraz, Natalia Ortega, Arnaud Chiolero
Summary: This study aimed to assess the reliability of self-reported weight and height values compared to measured values in children. The findings showed a high correlation between self-reported and measured values, but self-reported values tended to underestimate the actual measurements. Self-reported weight and height can be a reliable alternative to measurements, but caution should be taken when estimating the prevalence of over- or underweight.
Article
Biochemistry & Molecular Biology
Hui-Juan Yang, Ye Kang, Yi-Zi Li, Fang-Hua Liu, Shi Yan, Song Gao, Yun-Long Huo, Ting-Ting Gong, Qi-Jun Wu
Summary: This study aimed to investigate the associations between prediagnosis dietary choline intake and ovarian cancer survival. The findings suggest that higher intake of lipid-soluble choline and phosphatidylcholine are associated with improved overall survival among ovarian cancer patients.
Article
Endocrinology & Metabolism
Jing Jiang, Hao Wang, Kang Liu, Shiqi He, Zhaoyang Li, Yu Yuan, Kuai Yu, Pinpin Long, Jing Wang, Tingyue Diao, Xiaomin Zhang, Meian He, Huan Guo, Tangchun Wu
Summary: This study examined the association between complement C3 levels and incident type 2 diabetes mellitus (T2DM), and found that higher C3 levels were associated with an increased risk of T2DM. Furthermore, it was suggested that body mass index (BMI) might mediate the association between C3 and T2DM.
JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM
(2023)
Article
Endocrinology & Metabolism
Xuelun Zou, Leiyun Wang, Linxiao Xiao, Zihao Xu, Tianxing Yao, Minxue Shen, Yi Zeng, Le Zhang
Summary: The study revealed a significant positive association between obesity class I and II and ischemic stroke, while obesity class III was not related. Obesity was strongly associated with large artery stroke and cardioembolic stroke among all ischemic stroke subtypes in the obese population.
FRONTIERS IN ENDOCRINOLOGY
(2021)
Article
Nutrition & Dietetics
Mario Kasovic, Lovro Stefan, Pavel Piler, Martin Zvonar
Summary: The study found that children of mothers who were overweight/obese pre-pregnancy were more likely to report sports injuries, while children of underweight mothers had lower odds of reporting sports injuries. Additionally, increasing maternal physical activity was associated with a decreased risk of sports injuries in children.
Article
Endocrinology & Metabolism
Nana Wang, Yuying Li, Chuanji Guo
Summary: This study demonstrates that waist-corrected body mass index (wBMI), combining BMI and waist circumference measurements, is superior in predicting obesity and diabetes mellitus (DM). The study found a significant association between wBMI and the incidence of DM, with wBMI being a more reliable predictor compared to waist circumference, BMI, and waist-to-height ratio.
FRONTIERS IN ENDOCRINOLOGY
(2023)
Article
Oncology
Mathias Rask-Andersen, Emma Ivansson, Julia Hoglund Glund, Weronica E. Ek, Torgny Karlsson, Asa Johansson
Summary: Obesity is linked to various types of cancer, and the distribution of fat, which varies between sexes, has been suggested to be an independent risk factor. However, there is limited research on the sex-specific effects on cancer risk. In this study, we examined the effects of fat accumulation and distribution on cancer risk in both females and males. Our findings showed that adiposity traits were associated with most cancer types, and fat accumulation had a greater association with cancer compared to fat distribution. Additionally, the effects of fat accumulation or distribution on colorectal, esophageal, and liver cancer differed between sexes.
Article
Multidisciplinary Sciences
Yi-de Yang, Ming Xie, Yuan Zeng, Shuqian Yuan, Haokai Tang, Yanhui Dong, Zhiyong Zou, Bin Dong, Zhenghe Wang, Xiangli Ye, Xiuqin Hong, Qiu Xiao, Jun Ma
Summary: The study found that children with persistent obesity, newly developed obesity, or converting from obese to non-obese had significantly higher risk of high blood pressure. For children with general obesity (GOB) or abdominal obesity (AOB), a reduction of 0.21-0.88 kg/m(2) of baseline BMI (0.86-3.59%) or 0.009-0.024 of baseline WHtR (1.66-4.42%) was associated with a significant decrease in high blood pressure risk.
Article
Physiology
Qingmei Wang, Junwei Qian, Haoran Pan, Qianqian Ju
Summary: Background: Recent studies have shown a decline in students' fitness levels, which is important for their overall health and academic performance. This study aimed to investigate the relationship between body composition and upper limb physical fitness in Chinese students and identify the factors contributing to low physical fitness levels. The results showed an increase in male students' Body-Mass-Index (BMI) and a decrease in upper limb physical fitness. Body composition was found to be a predictor of upper limb physical fitness, and students with better body composition had higher grip strength, drape height, and anaerobic power.
FRONTIERS IN PHYSIOLOGY
(2023)
Article
Nutrition & Dietetics
Chengyao Tang, Ehab Salah Eshak, Kokoro Shirai, Akiko Tamakoshi, Hiroyasu Iso
Summary: Higher dietary intakes of vitamins B-1 and B-3 were inversely associated with mortality from ischemic heart disease, and a higher dietary intake of vitamin B-1 was inversely associated with a reduced risk of mortality from heart failure.
BRITISH JOURNAL OF NUTRITION
(2023)
Article
Oncology
Ayako Kato, Chika Okada, Ehab S. Eshak, Hiroyasu Iso, Akiko Tamakoshi
Summary: This study found that higher intake of alpha-linolenic acid (ALA) may be beneficial in lowering the risk of distal colon cancer. However, the intake of marine-derived n-3 polyunsaturated fatty acids (PUFA) was not associated with colorectal cancer (CRC) risk.
Article
Pediatrics
Kanami Tanigawa, Yoko Kawanishi, Satoyo Ikehara, Takashi Kimura, Kimiko Ueda, Tadashi Kimura, Keiichi Ozono, Hiroyasu Iso
Summary: This study examined the association between gestational weight gain (GWG) and the risk of overweight in 3-year-old children. The results showed a positive association between GWG and the risk of overweight, with both excessive and inadequate GWG being associated with increased risk.
Article
Public, Environmental & Occupational Health
Mizuki Sata, Kazumasa Yamagishi, Toshimi Sairenchi, Fujiko Irie, Keiko Sunou, Hiroshi Watanabe, Hiroyasu Iso, Hitoshi Ota
Summary: This study found that breastfeeding can prevent overweight and obesity in childhood, but there is insufficient evidence about its long-term impact on body size in adolescence and adulthood.
JOURNAL OF EPIDEMIOLOGY
(2023)
Article
Nutrition & Dietetics
Yuji Shimizu, Hirotomo Yamanashi, Yukiko Honda, Fumiaki Nonaka, Jun Miyata, Shin-Ya Kawashiri, Yuko Noguchi, Seiko Nakamichi, Yasuhiro Nagata, Takahiro Maeda
Summary: Aggressive endothelial repair contributes to the progression of structural and functional atherosclerosis, while inadequate endothelial repair exacerbates functional atherosclerosis. Aging increases the risk of insufficient endothelial repair. LDL cholesterol activation of endothelial repair is positively associated with structural atherosclerosis but inversely associated with functional atherosclerosis in older individuals. Combining structural and functional assessments may be informative for evaluating atherosclerosis in clinical practice.
Article
Cardiac & Cardiovascular Systems
Masayuki Teramoto, Kazumasa Yamagishi, Isao Muraki, Akiko Tamakoshi, Hiroyasu Iso
Summary: This study examined the effects of coffee and green tea consumption on cardiovascular disease mortality among people with severe hypertension. The results showed that heavy coffee consumption was associated with an increased risk of CVD mortality, while green tea consumption was not.
JOURNAL OF THE AMERICAN HEART ASSOCIATION
(2023)
Article
Gastroenterology & Hepatology
Ahmed Arafa, Ehab S. Eshak, Kokoro Shirai, Isao Muraki, Akiko Tamakoshi, Hiroyasu Iso
Summary: Daytime napping is associated with a higher risk of liver cancer, especially among older adults aged 60-70.
ANNALS OF HEPATOLOGY
(2023)
Article
Public, Environmental & Occupational Health
Kanami Tanigawa, Satoyo Ikehara, Meishan Cui, Yoko Kawanishi, Tadashi Kimura, Kimiko Ueda, Kazumasa Yamagishi, Hiroyasu Iso
Summary: Both short and long interpregnancy intervals (IPIs) are associated with an increased risk of preterm birth, especially in women with inadequate intake of dietary folate and folic acid supplementation during pregnancy. These findings are based on a nationwide birth cohort study conducted in Asia.
JOURNAL OF EPIDEMIOLOGY
(2023)
Article
Neurosciences
Rie Kishida, Kazumasa Yamagishi, Ai Ikeda, Mina Hayama-Terada, Yuji Shimizu, Isao Muraki, Mitsumasa Umesawa, Hironori Imano, Tomoko Sankai, Takeo Okada, Akihiko Kitamura, Masahiko Kiyama, Hiroyasu Iso
Summary: This study aimed to examine the relationship between serum folate levels and the risk of disabling dementia. A nested case-control study involving 13,934 Japanese individuals found that low serum folate levels were negatively associated with the risk of disabling dementia. After a 20.8-year follow-up, it was observed that low serum folate levels were associated with an increased risk of disabling dementia among Japanese individuals.
NUTRITIONAL NEUROSCIENCE
(2023)
Article
Cardiac & Cardiovascular Systems
Ai Koba, Kazumasa Yamagishi, Toshimi Sairenchi, Hiroyuki Noda, Fujiko Irie, Nobue Takizawa, Takuji Tomizawa, Hiroyasu Iso, Hitoshi Ota
Summary: This study investigated the risk factors associated with mortality from aortic diseases in a community-based Japanese cohort. The results showed that smoking, high blood pressure, high cholesterol, and low blood lipid levels were positively associated with mortality from aortic diseases, while diabetes was inversely associated.
JOURNAL OF THE AMERICAN HEART ASSOCIATION
(2023)
Article
Biochemistry & Molecular Biology
Yuji Shimizu, Naomi Hayashida, Hirotomo Yamanashi, Yuko Noguchi, Shin-Ya Kawashiri, Midori Takada, Kazuhiko Arima, Seiko Nakamichi, Yasuhiro Nagata, Takahiro Maeda
Summary: A cross-sectional study conducted on 536 Japanese individuals aged 60 to 69 years found a significant positive association between serum GDF-15 concentration and atherosclerosis. This association remained even after adjusting for thyroid function, renal function, and other known cardiovascular risk factors.
Article
Public, Environmental & Occupational Health
Takumi Matsumura, Isao Muraki, Ai Ikeda, Kazumasa Yamagishi, Kokoro Shirai, Nobufumi Yasuda, Norie Sawada, Manami Inoue, Hiroyasu Iso, Eric J. Brunner, Shoichiro Tsugane
Summary: In a long-term follow-up study, hobby engagement in both mid-life and late life was found to be associated with a lower risk of disabling dementia without a history of stroke. This finding is significant for individuals in mid-life when cognitive function is typically normal.
JOURNAL OF EPIDEMIOLOGY
(2023)
Article
Multidisciplinary Sciences
Keiko Yamada, Takashi Kimura, Meishan Cui, Eizaburo Tanaka, Yasuhiko Kubota, Satoyo Ikehara, Hiroyasu Iso
Summary: The aim of this cross-sectional study was to investigate the association between the presence of autistic traits in pregnant women and the prevalence and severity of antenatal pain. The study analyzed data from 89,068 pregnant women in Japan. Autistic traits were assessed using a Japanese version of the Autism-Spectrum Quotient short form, while antenatal pain was measured using the SF-8 bodily pain item. The study found a positive dose-response association between autistic traits and both mild and moderate-to-severe antenatal pain, with a stronger association observed for moderate-to-severe pain.
SCIENTIFIC REPORTS
(2023)
Article
Public, Environmental & Occupational Health
Keiko Ishimura, Ryoto Sakaniwa, Kokoro Shirai, Jun Aida, Kenji Takeuchi, Katsunori Kondo, Hiroyasu Iso
Summary: A three-year longitudinal study of Japanese adults aged >65 years found that the frequency of going outdoors is associated with the risk of poor oral health. The study showed that frequent outdoor activities can reduce the risk of oral health problems, and this association may be mediated through modifiable risk factors.
JOURNAL OF EPIDEMIOLOGY
(2023)
Article
Neurosciences
Adam Vacek, Grant Mair, Philip White, Philip M. Bath, Keith W. Muir, Rustam Al-Shahi Salman, Chloe Martin, David Dye, Francesca M. Chappell, Ruediger von Kummer, Malcolm Macleod, Nikola Sprigg, Joanna M. Wardlaw
Summary: This study evaluated the performance of e-ASPECTS software in delineating the extent of intracranial hemorrhage (ICH) on brain CT scans. The results showed that the software achieved excellent or good delineation of ICH extent in 71% of cases. However, it was more likely to over- or under-estimate the extent when ICH was more extensive, intraventricular, or extra-axial.
JOURNAL OF STROKE & CEREBROVASCULAR DISEASES
(2024)
Article
Neurosciences
Mathias Jacobsen Bach, Audrone Jakubauskaite, Ian Law, Otto Molby Henriksen, Inger Havsteen, Alexander Cuculiza Henriksen, Sverre Rosenbaum, Lisbeth Marner
Summary: This study found that the rCBFacz value after ACZ challenge can serve as an important indicator for predicting future cerebrovascular events, with high accuracy and prognostic value.
JOURNAL OF STROKE & CEREBROVASCULAR DISEASES
(2024)
Article
Neurosciences
Tak Kyu Oh, Saeyeon Kim, In-Ae Song
Summary: The study found that many survivors of nontraumatic intracranial hemorrhage in South Korea experience unemployment, decreased household income, and newly acquired disability after intensive care unit admission. However, these changes are not associated with 2-year all-cause mortality.
JOURNAL OF STROKE & CEREBROVASCULAR DISEASES
(2024)
Article
Neurosciences
Eduardo Sousa de Melo, Rodrigo de Paiva Bezerra, Arthur Cesario de Holanda, Maria Junia Lira e Silva, Paloma Peter Travassos, Tayne Fernanda Lemos da Silva, Genova Maria de Azevedo Oliveira, Silvia Marinho Martins Alves, Carolina de Araujo Medeiros, Maria das Neves Dantas da Silveira Barros, Wilson Alves de Oliveira, Gisele Sampaio Silva, Luciana Patrizia Alves de Andrade Valenca
Summary: Cardiac involvement has been found to be the predominant factor correlated with stroke in Chagas disease. While atherosclerosis-related risk factors are prevalent, their influence on ischemic stroke in Chagas disease appears limited.
JOURNAL OF STROKE & CEREBROVASCULAR DISEASES
(2024)
Article
Neurosciences
Pingping Zheng, Ning Zhang, Zixi Chen
Summary: This case presents a rare infectious cause of stroke and air embolism involving a pulmonary abscess and pulmonary vein thrombosis. Early detection, diagnosis, and appropriate treatment of infected systemic embolism in young patients are crucial to prevent serious complications.
JOURNAL OF STROKE & CEREBROVASCULAR DISEASES
(2024)
Article
Neurosciences
Filippo Luca Gurgoglione, Luigi Vignali, Maria Alberta Cattabiani, Emilia Solinas, Giorgio Benatti, Iacopo Tadonio, Federico Barocelli, Chiara Dizdari, Domenico Tuttolomondo, Diego Ardissino, Francesco Nicolini, Giampaolo Niccoli
Summary: The incidence of recurrent ischemic neurological events after transcatheter patent foramen ovale closure is relatively low. Obesity, Risk of Paradoxical Embolism score < 7, and migraine are independent positive predictors of recurrent stroke or transient ischemic attack.
JOURNAL OF STROKE & CEREBROVASCULAR DISEASES
(2024)
Article
Neurosciences
Angelo Cascio Rizzo, Ghil Schwarz, Amedeo Cervo, Giuditta Giussani, Chiara Ceresa, Antonella Gatti, Fausto De Angeli, Cristina Motto, Angelo Guccione, Rachele Tortorella, Giuseppe Granata, Claudia Rollo, Antonio Macera, Mariangela Piano, Guglielmo Pero, Elio Clemente Agostoni
Summary: This study aimed to evaluate the efficacy and safety of endovascular treatment (EVT) in primary and EVT-induced secondary medium-vessel occlusions (MeVO). The results showed that primary MeVO had poorer outcomes in terms of complications, EVT efficacy, and the proportion of patients with a modified Rankin Scale (mRS) of 0-2 at 3 months compared to exclusive large-vessel occlusion (LVO). However, EVT-induced secondary MeVO showed similar safety and efficacy outcomes as exclusive LVO and had better outcomes in terms of mRS 0-2 compared to primary MeVO.
JOURNAL OF STROKE & CEREBROVASCULAR DISEASES
(2024)
Article
Neurosciences
Jing Zhang, Chenming Wei, Jian Wu
Summary: This case report describes a patient with Bloom syndrome who developed acute cerebral infarction along with elevated antiphospholipid antibodies, suggesting a possible association between immune and coagulation abnormalities caused by Bloom syndrome and the development of acute cerebral infarction.
JOURNAL OF STROKE & CEREBROVASCULAR DISEASES
(2024)
Article
Neurosciences
Yunxia Zhou, Shenglan He, Yanhong Hu
Summary: Compared with clopidogrel, DAPT with ticagrelor plus aspirin was associated with significantly lower thromboembolic events without an increase in hemorrhagic events in the treatment of intracranial aneurysms, according to the one-year clinical outcome analysis. However, larger upcoming trials are needed to confirm the effectiveness and safety of ticagrelor-associated DAPT.
JOURNAL OF STROKE & CEREBROVASCULAR DISEASES
(2024)
Article
Neurosciences
Edvania Andrade de Moura Silva, Ludmilla Ribeiro Batista, Marcela Aline Fernandes Braga, Luci Fuscaldi Teixeira-Salmela, Christina Danielli Coelho de Morais Faria, Iza Faria-Fortini
Summary: The study found that stroke severity is the best predictor of self-perceived manual ability at both three and six months after stroke. Age, although significant, contributes little to the prediction of manual ability.
JOURNAL OF STROKE & CEREBROVASCULAR DISEASES
(2024)
Article
Neurosciences
Sidarrth Prasad, Erica M. Jones, Mehari Gebreyohanns, Veronica Aguilera, DaiWai M. Olson, Jane A. Anderson, Sean I. Savitz, Salvador C. Flores, Steven J. Warach, Charlotte E. Rhodes, Mark P. Goldberg, Nneka L. Ifejika
Summary: This study identified the barriers and facilitators to adopting tenecteplase (TNK) as a thrombolytic treatment for acute ischemic stroke (AIS) by conducting qualitative research with stroke clinicians in Texas. The findings suggest that providing evidence and identifying key change processes can help clinicians achieve consensus on adopting TNK for AIS treatment.
JOURNAL OF STROKE & CEREBROVASCULAR DISEASES
(2024)
Article
Neurosciences
Jeshma Jayan, Sunil K. Narayan, Yasmin Nesha Haniffa, Navin Kumar
Summary: This study investigated the effects of transcranial electrical and magnetic stimulation on somatosensory evoked potentials in chronic ischemic stroke patients, finding that the real tDCS and rTMS combination results in significant improvement and is safe for use.
JOURNAL OF STROKE & CEREBROVASCULAR DISEASES
(2024)
Article
Neurosciences
Phoebe M. Tran, Cenjing Zhu, William T. Harris II, Sajeesh K. Kamala Raghavan, Agricola Odoi, Liem Tran
Summary: This study assessed the geographic accessibility of stroke rehabilitation facilities in Tennessee. The study found that rural counties had significantly longer travel distances and times compared to urban counties. Counties with high and medium stroke prevalence also had higher travel times and distances compared to low stroke prevalence counties. Therefore, addressing transportation barriers and implementing tele-rehabilitation are crucial for improving access to stroke aftercare in these areas.
JOURNAL OF STROKE & CEREBROVASCULAR DISEASES
(2024)
Article
Neurosciences
Lili Xu, Shuaiyu Chen, Jing Xu, Yanyan Shi, Zhihang Huang, Meng Wang, Ziqiao Wei, Hui Cao, Junshan Zhou, Wei Wang, Mingyang Du
Summary: This study found that the Chinese Visceral Adiposity Index (CVAI) is positively correlated with 90-day poor outcome in Chinese ischemic stroke patients after endovascular thrombectomy (EVT).
JOURNAL OF STROKE & CEREBROVASCULAR DISEASES
(2024)
Article
Neurosciences
Guangying Wu, Shuhua Li, Min Luo, Xiaotian Li, Xinghua Zhu, Junhuai Zhang, Qian He, Qian Yang, Guojiang Zhao, Shasha Luo, Zhijie Yang
Summary: The study aimed to investigate the relationship between serum alkaline phosphatase (ALP) levels and the severity and prognosis of intracerebral hemorrhage (ICH). The results showed that serum ALP levels in ICH patients were significantly elevated and correlated with hematoma volume and Glasgow coma scale (GCS) score. High serum ALP levels may serve as a potential predictor for the severity and unfavorable prognosis of ICH.
JOURNAL OF STROKE & CEREBROVASCULAR DISEASES
(2024)