期刊
JOURNAL OF STROKE & CEREBROVASCULAR DISEASES
卷 22, 期 8, 页码 1428-1431出版社
ELSEVIER SCIENCE BV
DOI: 10.1016/j.jstrokecerebrovasdis.2012.12.009
关键词
Diffusion-weighted imaging; susceptibility-weighted imaging; ischemic-penumbra; misery-perfusion; brain; magnetic resonance imaging
Susceptibility-weighted imaging (SWI) has recently attracted attention for its ability to investigate acute stroke pathophysiology. SWI detects an increased ratio of deoxyhemoglobin to oxyhemoglobin in cerebral venous compartments, which can illustrate cerebral misery perfusion with a compensatory increase of oxygen extraction fraction in the hypoperfused brain. In this study we make the first case report of blunt cervical trauma leading to a stroke, demonstrating the disparity between diffusion-weighted imaging (DWI) and SWI changes, or DWI-SWI mismatch, in the acute ischemic brain. The area of mismatch between a smaller DWI cytotoxic edema and a larger SWI misery perfusion in our patient matured into a complete infarction with time. The DWI-SWI mismatch may signify the presence of an ischemic penumbra, and provide information about viability of the brain tissue at risk of potential infarction if without early reperfusion.
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