Environmental perception and epigenetic memory: mechanistic insight throughFLC

Phenotypic evolution through variation in splicing of the noncoding RNACOOLAIR

(2015) Peijin Li et al.   GENES & DEVELOPMENT

A methyltransferase required for proper timing of the vernalization response inArabidopsis

(2015) Joohyun Lee et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Vernalizing cold is registered digitally atFLC

(2015) Andrew Angel et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

How is FLC repression initiated by cold?

(2015) Chris A. Helliwell et al.   TRENDS IN PLANT SCIENCE

Local chromatin environment of a Polycomb target gene instructs its own epigenetic inheritance

(2015) Scott Berry et al.   eLife

Antagonistic Roles for H3K36me3 and H3K27me3 in the Cold-Induced Epigenetic Switch at Arabidopsis FLC

(2014) Hongchun Yang et al.   CURRENT BIOLOGY

MultipleFLChaplotypes defined by independentcis-regulatory variation underpin life history diversity inArabidopsis thaliana

(2014) Peijin Li et al.   GENES & DEVELOPMENT

Small but sturdy: small RNAs in cellular memory and epigenetics

(2014) E. Stuwe et al.   GENES & DEVELOPMENT

Nascent RNA interaction keeps PRC2 activity poised and in check

(2014) Syuzo Kaneko et al.   GENES & DEVELOPMENT

Gene Silencing Triggers Polycomb Repressive Complex 2 Recruitment to CpG Islands Genome Wide

(2014) Eva Madi Riising et al.   MOLECULAR CELL

Functional Consequences of Splicing of the Antisense Transcript COOLAIR on FLC Transcription

(2014) Sebastian Marquardt et al.   MOLECULAR CELL

Epigenetic reprogramming that prevents transgenerational inheritance of the vernalized state

(2014) Pedro Crevillén et al.   NATURE

A strand-specific switch in noncoding transcription switches the function of a Polycomb/Trithorax response element

(2014) Veronika A Herzog et al.   NATURE GENETICS

What are memories made of? How Polycomb and Trithorax proteins mediate epigenetic memory

(2014) Philipp A. Steffen et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

AntisenseCOOLAIRmediates the coordinated switching of chromatin states atFLCduring vernalization

(2014) Tibor Csorba et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Antisense-mediated FLC transcriptional repression requires the P-TEFb transcription elongation factor

(2014) Z.-W. Wang et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

H3K27me and PRC2 transmit a memory of repression across generations and during development

(2014) L. J. Gaydos et al.   SCIENCE

Evolutionary conservation of cold-induced antisense RNAs of FLOWERING LOCUS C in Arabidopsis thaliana perennial relatives

(2014) Loren Castaings et al.   Nature Communications

Jumonji demethylases moderate precocious flowering at elevated temperature via regulation of FLC in Arabidopsis

(2014) Eng-Seng Gan et al.   Nature Communications

Arabidopsis Polycomb Repressive Complex 2 binding sites contain putative GAGA factor binding motifs within coding regions of genes

(2013) Weiwei Deng et al.   BMC GENOMICS

Arabidopsis MSI1 connects LHP1 to PRC2 complexes

(2013) Maria Derkacheva et al.   EMBO JOURNAL

NATURAL VARIATION IN EPIGENETIC GENE REGULATION AND ITS EFFECTS ON PLANT DEVELOPMENTAL TRAITS

(2013) Franziska Turck et al.   EVOLUTION

Physical clustering of FLC alleles during Polycomb-mediated epigenetic silencing in vernalization

(2013) S. Rosa et al.   GENES & DEVELOPMENT

Promiscuous RNA binding by Polycomb repressive complex 2

(2013) Chen Davidovich et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

Noncoding RNAs prevent spreading of a repressive histone mark

(2013) Claudia Keller et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

PRC2 binds active promoters and contacts nascent RNAs in embryonic stem cells

(2013) Syuzo Kaneko et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

Combinatorial functions of diverse histone methylations inArabidopsis thalianaflowering time regulation

(2013) Sarfraz Shafiq et al.   NEW PHYTOLOGIST

A Histone Mutant Reproduces the Phenotype Caused by Loss of Histone-Modifying Factor Polycomb

(2013) A. R. Pengelly et al.   SCIENCE

R-Loop Stabilization Represses Antisense Transcription at the Arabidopsis FLC Locus

(2013) Q. Sun et al.   SCIENCE

Chromatin Sampling—An Emerging Perspective on Targeting Polycomb Repressor Proteins

(2013) Robert J. Klose et al.   PLoS Genetics

TrxG and PcG Proteins but Not Methylated Histones Remain Associated with DNA through Replication

(2012) Svetlana Petruk et al.   CELL

Asymmetrically Modified Nucleosomes

(2012) Philipp Voigt et al.   CELL

Bistability, Bifurcations, and Waddington's Epigenetic Landscape

(2012) James E. Ferrell   CURRENT BIOLOGY

A gene loop containing the floral repressor FLC is disrupted in the early phase of vernalization

(2012) Pedro Crevillén et al.   EMBO JOURNAL

A stochastic model of chromatin modification: Cell population coding of winter memory in plants

(2012) Akiko Satake et al.   JOURNAL OF THEORETICAL BIOLOGY

Kinetic Competition between RNA Polymerase II and Sen1-Dependent Transcription Termination

(2012) Dane Z. Hazelbaker et al.   MOLECULAR CELL

Quantitative Modulation of Polycomb Silencing Underlies Natural Variation in Vernalization

(2012) V. Coustham et al.   SCIENCE

Flowering time control: another window to the connection between antisense RNA and chromatin

(2012) Robert Ietswaart et al.   TRENDS IN GENETICS

Mechanisms for the Inheritance of Chromatin States

(2011) Danesh Moazed   CELL

FT, A Mobile Developmental Signal in Plants

(2011) Philip A. Wigge   CURRENT BIOLOGY

H3K36 Methylation Antagonizes PRC2-mediated H3K27 Methylation

(2011) Wen Yuan et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

A Polycomb-based switch underlying quantitative epigenetic memory

(2011) Andrew Angel et al.   NATURE

The Polycomb complex PRC2 and its mark in life

(2011) Raphaël Margueron et al.   NATURE

A pre-initiation complex at the 3′-end of genes drives antisense transcription independent of divergent sense transcription

(2011) Struan C. Murray et al.   NUCLEIC ACIDS RESEARCH

Polycomb Group Complexes Mediate Developmental Transitions in Plants

(2011) S. Holec et al.   PLANT PHYSIOLOGY

Vernalization-Repression of Arabidopsis FLC Requires Promoter Sequences but Not Antisense Transcripts

(2011) Chris A. Helliwell et al.   PLoS One

Major-Effect Alleles at Relatively Few Loci Underlie Distinct Vernalization and Flowering Variation in Arabidopsis Accessions

(2011) Amy Strange et al.   PLoS One

Histone modification: cause or cog?

(2011) Steven Henikoff et al.   TRENDS IN GENETICS

Chromatin as a potential carrier of heritable information

(2010) Paul D Kaufman et al.   CURRENT OPINION IN CELL BIOLOGY

Regulation of the floral repressor gene FLC: the complexity of transcription in a chromatin context

(2010) Pedro Crevillén et al.   CURRENT OPINION IN PLANT BIOLOGY

The Spen Family Protein FPA Controls Alternative Cleavage and Polyadenylation of RNA

(2010) Csaba Hornyik et al.   DEVELOPMENTAL CELL

cis-Regulatory Elements and Chromatin State Coordinately Control Temporal and Spatial Expression of FLOWERING LOCUS T in Arabidopsis

(2010) J. Adrian et al.   PLANT CELL

Transcription-dependence of histone H3 lysine 27 trimethylation at the Arabidopsis polycomb target gene FLC

(2010) Diana Mihaela Buzas et al.   PLANT JOURNAL

Robust control of the seasonal expression of the Arabidopsis FLC gene in a fluctuating environment

(2010) S. Aikawa et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Vernalization-Mediated Epigenetic Silencing by a Long Intronic Noncoding RNA

(2010) J. B. Heo et al.   SCIENCE

Molecular Signals of Epigenetic States

(2010) Roberto Bonasio et al.   SCIENCE

Genome-Wide Kinetics of Nucleosome Turnover Determined by Metabolic Labeling of Histones

(2010) R. B. Deal et al.   SCIENCE

Long Noncoding RNA as Modular Scaffold of Histone Modification Complexes

(2010) M.-C. Tsai et al.   SCIENCE

Polycomb Proteins Remain Bound to Chromatin and DNA during DNA Replication In Vitro

(2009) Nicole J. Francis et al.   CELL

Cold-induced silencing by long antisense transcripts of an Arabidopsis Polycomb target

(2009) Szymon Swiezewski et al.   NATURE

PEP1 regulates perennial flowering in Arabis alpina

(2009) Renhou Wang et al.   NATURE

Role of the polycomb protein EED in the propagation of repressive histone marks

(2009) Raphael Margueron et al.   NATURE

Control of alternative splicing through siRNA-mediated transcriptional gene silencing

(2009) Mariano Alló et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

ARABIDOPSIS TRITHORAX-RELATED7 Is Required for Methylation of Lysine 4 of Histone H3 and for Transcriptional Activation of FLOWERING LOCUS C

(2009) Y. Tamada et al.   PLANT CELL

Establishment of the Winter-Annual Growth Habit via FRIGIDA-Mediated Histone Methylation at FLOWERING LOCUS C in Arabidopsis

(2009) D. Jiang et al.   PLANT CELL

SET DOMAIN GROUP25 Encodes a Histone Methyltransferase and Is Involved in FLOWERING LOCUS C Activation and Repression of Flowering

(2009) A. Berr et al.   PLANT PHYSIOLOGY

Targeted 3' Processing of Antisense Transcripts Triggers Arabidopsis FLC Chromatin Silencing

(2009) F. Liu et al.   SCIENCE

Bistability, Epigenetics, and Bet-Hedging in Bacteria

(2008) Jan-Willem Veening et al.   Annual Review of Microbiology

A Repressor Complex Governs the Integration of Flowering Signals in Arabidopsis

(2008) Dan Li et al.   DEVELOPMENTAL CELL

A model for transmission of the H3K27me3 epigenetic mark

(2008) Klaus H. Hansen et al.   NATURE CELL BIOLOGY

ARABIDOPSIS TRITHORAX1 Dynamically Regulates FLOWERING LOCUS C Activation via Histone 3 Lysine 4 Trimethylation

(2008) S. Pien et al.   PLANT CELL

Resetting and regulation ofFLOWERING LOCUS Cexpression during Arabidopsis reproductive development

(2008) Jean Choi et al.   PLANT JOURNAL

Resetting of FLOWERING LOCUS C expression after epigenetic repression by vernalization

(2008) C. C. Sheldon et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

A PHD-Polycomb Repressive Complex 2 triggers the epigenetic silencing of FLC during vernalization

(2008) F. De Lucia et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA