Article
Chemistry, Analytical
Sutthima Sriprasertsuk, Simone C. Mathias, John R. Varcoe, Carol Crean
Summary: PPy.SDS-coated carbon fiber electrodes demonstrated enhanced drug sensing capabilities compared to bare carbon fibers, with a 14-fold increase in electrochemical surface area. The use of a large counter anion as dopant, such as dodecyl sulfate, resulted in a greater drug sensing response. Differential pulse voltammetry (DPV) with PPy.SDS fiber electrodes was able to detect paracetamol with a detection limit of 34 μM and a linear response range of 50-500 μM, even in the presence of interferents like dopamine and ascorbic acid at 100 μM concentrations. This indicates the potential for real-world applications of PPy.SDS electrodes in drug sensing, with the ability to detect anti-psychotic medication like clozapine at low concentrations.
JOURNAL OF ELECTROANALYTICAL CHEMISTRY
(2021)
Article
Biochemical Research Methods
Nouman Almofti, Soledad Gonzalez-Rubio, Ana Ballesteros-Gomez, Eloy Girela, Soledad Rubio
Summary: This study optimized and validated a simple, time-saving, and environmentally friendly sample preparation method using supramolecular solvents (SUPRAS) for the extraction of selected drug-facilitated sexual assault (DFSA) substances from human urine. The method involved stirring, centrifugation, and dilution, and the SUPRAS extracts were analyzed by LC-MS/MS. The method was successfully validated for various DFSA compounds, with high extraction efficiency and acceptable matrix effects, making it suitable for monitoring illegal drugs in DFSA cases by forensic laboratories.
ANALYTICAL AND BIOANALYTICAL CHEMISTRY
(2023)
Article
Chemistry, Multidisciplinary
Skyler D. D. Ware, Wendy Zhang, David J. J. Charboneau, Channing K. K. Klein, Sarah E. E. Reisman, Kimberly A. A. See
Summary: This study investigates factors influencing the electrochemical reduction of Sm(III) to Sm(II), including the effects of supporting electrolyte, electrode material, and Sm precursor. The coordination strength of the counteranion of the Sm salt is found to affect the reversibility and redox potential of the Sm(II)/(III) couple, and the counteranion primarily determines the reducibility of Sm(III). Electrochemically generated SmI2 performs similarly to commercial SmI2 solutions in a proof-of-concept reaction.
CHEMISTRY-A EUROPEAN JOURNAL
(2023)
Article
Chemistry, Physical
Karla Caroline de Freitas Araujo, Emily Cintia Tossi de Araujo Costa, Danyelle Medeiros de Araujo, Elisama V. Santos, Carlos A. Martinez-Huitle, Pollyana Souza Castro
Summary: In the development of electrochemical sensors, carbon micro-structured or micro-materials have been widely used as supports/modifiers to improve the performance of bare electrodes. However, no attempts for electroanalytical determination of caffeine with CF microelectrode have been reported in the literature. Therefore, a homemade CF-microelectrode was fabricated and used to determine caffeine in soft beverage samples.
Article
Chemistry, Analytical
Fernanda C. O. L. Martins, Djenaine De Souza
Summary: This work presents the development of an electroanalytical method for detecting nanomolar levels of selenium, utilizing a silver solid amalgam electrode modified with a stable mercury film and square-wave cathodic adsorptive stripping voltammetry. The optimized parameters resulted in satisfactory results, providing potential for selenium detection in food and beverage samples.
MICROCHEMICAL JOURNAL
(2021)
Article
Chemistry, Analytical
Ghadeer A. R. Y. Suaifan, Mohammad F. Khanfar, Mayadah B. Shehadeh, Asmaa Alnajajrah, Raghad Abuhamdan, Sameer Ahmad Hasan
Summary: This study successfully developed an electroanalytical electrode for the detection of albendazole (ABZ) active ingredient in pharmaceutical dosage form and contaminated animal-derived products. The modified electrode demonstrated high sensitivity and applicability, making it suitable for quality control in the pharmaceutical and food industry.
Review
Pharmacology & Pharmacy
K. Skov, S. S. Johansen, K. Linnet, M. K. K. Nielsen
Summary: The toxicological findings in DFSA cases are comparable across different countries, with ethanol, cocaine, cannabis being among the most frequently detected substances. Typical DFSA cases primarily involve women in their mid-twenties and an acquaintance as the perpetrator.
EUROPEAN REVIEW FOR MEDICAL AND PHARMACOLOGICAL SCIENCES
(2022)
Article
Chemistry, Analytical
Diele A. G. Araujo, Ana C. M. Oliveira, Lauro A. Pradela-Filho, Regina M. Takeuchi, Andre L. Santos
Summary: Voltammetry and amperometry are inexpensive and high-performance analytical techniques, but lack selectivity in complex matrices. A new cost-effective approach was presented in this study to combine sample pretreatment and voltammetric detection into a single step, achieving fast quantification of sulfite in beverage samples. The proposed system, despite its simplicity and low cost, showed good analytical performance and can be applied to quantify any volatile electroactive species, providing a unique way to assess real-time extraction curves and optimize new gas extraction procedures.
ANALYTICA CHIMICA ACTA
(2021)
Article
Multidisciplinary Sciences
Khalid Mahmoud Hassan, ElKhabiry Shaban, Ghada Mahmoud Elhaddad, Sameha Hassan Shokair, Mehboobali Pannipara, Ibrahim ElTantawy ElSayed
Summary: A new heterocyclic azodye, CQAPDN, was synthesized and its structure was elucidated. The dye showed good dyeing performance and fastness properties on polyester fibers. Electrochemical studies revealed the excellent electrocatalytic activity of CQAPDN and potential for azo-group removal using controlled potential electrolysis technique.
JOURNAL OF KING SAUD UNIVERSITY SCIENCE
(2022)
Article
Chemistry, Analytical
Romana Jarosova, Adam D. Douglass, Michael A. Johnson
Summary: In this study, a waveform for the measurement of oxytocin was optimized using carbon-fiber microelectrodes and flow injection analysis. The method achieved a low limit of quantitation and was successfully applied to measure oxytocin release in the brains of genetically engineered zebrafish.
ANALYTICAL CHEMISTRY
(2022)
Article
Chemistry, Physical
Gulsah Congur
Summary: A novel electrochemical sensor for phenol detection was successfully developed with lower detection limits using m-GMN/c-PGEs, demonstrating good detection performance and selectivity in water samples.
SURFACES AND INTERFACES
(2021)
Article
Chemistry, Analytical
Sarbjeet Kaur, Shalini, Bilal Ahmad Shiekh, Vipan Kumar, Inderpreet Kaur
Summary: A new compound TNFC was synthesized and confirmed by various experimental methods, and then successfully applied as a receptor for Cu2+ in differential pulse voltammetric and potentiometric sensors for quantification.
JOURNAL OF ELECTROANALYTICAL CHEMISTRY
(2022)
Article
Medicine, Legal
Keiko Sasaki, Noriaki Shima, Tooru Kamata, Akari Ishikawa, Atsushi Nitta, Misato Wada, Shihoko Nakano-Fujii, Hidenao Kakehashi, Takako Sato, Munehiro Katagi
Summary: Quantitative hair analysis of different hypnotics using LC-MS/MS indicated similar incorporation ratios among four benzodiazepines, allowing for estimation of other benzodiazepines with similar structures in hair. However, the distribution of drugs in hair varied depending on hair color, with lipophilic ZP showing a higher incorporation ratio compared to benzodiazepines. The study also demonstrated the application of the data to drug-facilitated sexual assault cases.
FORENSIC SCIENCE INTERNATIONAL
(2021)
Article
Chemistry, Analytical
Reem Zeitoun, Asim Biswas
Summary: The study examined the feasibility of pure cobalt, molybdenum, and their alloy as phosphate sensors, with the alloy showing good selectivity but a high limit of detection and long response time.
Article
Chemistry, Analytical
Michael R. Shaltry, Prabhat K. Tripathy, Tae-Sic Yoo, Guy L. Fredrickson
Summary: The study utilized tungsten rods as working and counter electrodes to conduct electrochemical measurements on YCl3, ScCl3, GdCl3, and MgCl2 in a molten LiCl-KCl eutectic. Analysis of cyclic voltammetry data provided values for diffusion coefficients, exchange current density, and charge transfer resistance, and discussed the effectiveness of normalization techniques for comparing experimental results.
JOURNAL OF ELECTROANALYTICAL CHEMISTRY
(2021)
Article
Chemistry, Analytical
Kevin C. Honeychurch, Gwen M. Davidson, Emma Brown, John P. Hart
ANALYTICA CHIMICA ACTA
(2015)
Article
Chemistry, Analytical
Kevin C. Honeychurch
ANALYTICAL METHODS
(2015)
Article
Biochemical Research Methods
Samira Inacia Santos e Silva, Paul Bowdler, Danielle Giltrow, Stephanie Riddell, Kevin C. Honeychurch
DRUG TESTING AND ANALYSIS
(2016)
Article
Chemistry, Analytical
James Robson, Stephen Townsend, Paul Bowdler, Kevin C. Honeychurch
Article
Biochemical Research Methods
Kevin C. Honeychurch, Lucy Gilbert, John P. Hart
ANALYTICAL AND BIOANALYTICAL CHEMISTRY
(2010)
Article
Chemistry, Analytical
Kevin C. Honeychurch, Ai Teng Chong, Khalil Elamin, John P. Hart
ANALYTICAL METHODS
(2012)
Article
Chemistry, Analytical
Mai Shafei, Kevin C. Honeychurch
ANALYTICAL METHODS
(2013)
Article
Chemistry, Analytical
Natasha D. McGuire, Kevin C. Honeychurch, John P. Hart
Article
Chemistry, Analytical
Kevin C. Honeychurch, Saman Al-Berezanchi, John P. Hart
Article
Chemistry, Analytical
Kevin C. Honeychurch, Adrian Crew, Hannah Northall, Stuart Radbourne, Owian Davies, Sam Newman, John P. Hart
Article
Chemistry, Analytical
Xianglu Peng, Melanie Brown, Paul Bowdler, Kevin C. Honeychurch
INTERNATIONAL JOURNAL OF ANALYTICAL CHEMISTRY
(2020)
Article
Chemistry, Analytical
Auwal M. Musa, Janice Kiely, Richard Luxton, Kevin C. Honeychurch
Summary: This study investigates the potential use of graphene-based electrodes in electrochemical determination of estradiol using amperometric techniques. Graphene, a carbon-based nanomaterial, has unique properties that make it ideal for electrochemical sensing. Different types of graphene-based electrodes are evaluated for their electrochemical properties and structural characteristics. The study also examines the possibility of using these electrodes for determining estradiol levels in tap water samples.
Article
Chemistry, Analytical
Margaret Sotom, Paul Bowdler, Kevin C. Honeychurch
Summary: A liquid chromatography-tandem mass spectrometry screening method in sweat was developed for the simultaneous determination of licit drugs, illicit drugs, and metabolites. The method was linear and had limits of quantitation and detection suitable for drug analysis. The study showed that sweat patches can be used to indicate an individual's drug use.
ANALYTICAL METHODS
(2023)
Article
Chemistry, Analytical
Sarah Cook, Kevin C. Honeychurch
Summary: The study demonstrates the possibility of using an electrochemical technique as a semi-quantitative presumptive test for the detection of blood residues. The method is based on the cyclic voltammetric behaviour of methylene blue mediated detection of hemoglobin, showing successful identification of blood residues on cloth with few interferences.
ANALYTICAL METHODS
(2021)
Article
Medicine, Legal
Paul Bowdler, Ella Gale, Freya Bryant, Samuel Codd, Sophie Hudd, Reece Longden, Paul White, Kevin C. Honeychurch
FORENSIC SCIENCE INTERNATIONAL
(2020)