期刊
JOURNAL OF SOL-GEL SCIENCE AND TECHNOLOGY
卷 89, 期 1, 页码 284-294出版社
SPRINGER
DOI: 10.1007/s10971-018-4759-y
关键词
Ca(Zn(OH)(3))(2)center dot 2H(2)O and ZnO NPs; Antimicrobial properties; MIC; Agar-well diffusion method; Biodeterioration; Structural damage
资金
- National Council for Science and Technology (Consejo Nacional de Ciencia y Tecnologia [CONACyT]) of the Fronteras de la Ciencia 138 project
- CONACyT [MSC 282192]
The process of biodeterioration is one of the main problems affecting historical monuments and buildings. On rock surfaces, different types of microorganisms establish in the most adequate niches and accelerate degradation, leading to the irreversible loss of cultural heritage. Therefore, new ways to preserve cultural heritage must be urgently studied to prevent such damage. In this study, the broad-spectrum antimicrobial activity of calcium zinc hydroxide dehydrate [Ca(Zn(OH)(3))(2)2H(2)O] (CZ) and zinc oxide (ZnO) nanoparticles synthesized by the sol-gel method is examined against fungal and bacterial model organisms. The selected microbes were inhibited by both nanoparticles, yet CZ was the most effective, with a bactericidal activity of 1.25 to 5mg/mL and a fungicidal activity of 0.625mg/mL. Both nanoparticles caused structural damage to the evaluated fungal cells, resulting in morphological changes and affecting the germination of conidia. For the first time in the literature, the antibacterial activity and the mode of action of CZ are reported. In conclusion, CZ nanoparticles are shown to be potential candidates for the treatment of rock surfaces of built cultural heritage
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