Article
Clinical Neurology
Luc Masset, Milan Nigam, Anne Ladarre, Marie Vidailhet, Smaranda Leu-Semenescu, Philippe Fossati, Isabelle Arnulf, Jean-Baptiste Maranci
Summary: Dreams during REM sleep can help reduce negative emotions, as shown by the study on emotional dynamics. Previous studies were limited to dream reports, but by studying individuals with REM sleep behavior disorder (RBD), researchers gained direct access to observe emotional dream behaviors. Analysis of 17 participants with RBD and 39.7 hours of REM sleep video revealed that emotional behaviors follow a biphasic temporal course, with an initial increase in frequency followed by a progressive decrease. Negative emotional behaviors occurred earlier than positive and neutral behaviors, and rapid succession of emotions of opposite valence was observed to prevent prolonged periods of negative emotions.
Article
Biology
Brittany J. Bush, Caroline Donnay, Eva-Jenee A. Andrews, Darielle Lewis-Sanders, Cloe L. Gray, Zhimei Qiao, Allison J. Brager, Hadiya Johnson, Hamadi C. S. Brewer, Sahil Sood, Talib Saafir, Morris Benveniste, Ketema N. Paul, J. Christopher Ehlen
Summary: Resilience, the ability to overcome stressful conditions, varies significantly among individuals and is influenced by sleep amount and sleep regulation in the prefrontal cortex.
Article
Biochemistry & Molecular Biology
Pao-Huan Chen, Cheng-Chih Chung, Shuen-Hsin Liu, Yu-Hsun Kao, Yi-Jen Chen
Summary: Lithium treatment can improve cardiac dysfunction caused by REM sleep deprivation and alleviate fibrosis. The potential mechanisms may involve the regulation of TGF-β, angiotensin II, and Ca2+ signaling.
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
(2022)
Article
Peripheral Vascular Disease
Rong Ren, Ye Zhang, Linghui Yang, Yuan Shi, Naima Covassin, Xiangdong Tang
Summary: This study aimed to quantify the independent association between arousals during REM/NREM sleep and prevalent hypertension. The results showed a significant dose-response relationship between arousal index during REM sleep and hypertension, while arousal index during NREM sleep was not a significant predictor of hypertension.
JOURNAL OF HYPERTENSION
(2023)
Article
Neurosciences
GoEun Han, Sumire Matsumoto, Javier Diaz, Robert W. W. Greene, Kaspar E. E. Vogt
Summary: Blocking calcium entry through L-type VGCCs does not interfere with EEG delta oscillations or their homeostatic regulation, despite prior evidence from calcium channel knockout mice.
FRONTIERS IN NEUROSCIENCE
(2022)
Article
Clinical Neurology
Cole D. Stang, Aidan F. Mullan, Mania Hajeb, Emanuele Camerucci, Pierpaolo Turcano, Peter Martin, Michelle M. Mielke, Keith A. Josephs, James H. Bower, Erik K. St Louis, Bradley F. Boeve, Rodolfo Savica
Summary: The study revealed that the prevalence of rapid eye movement (REM) sleep behavior disorder (RBD) increased over time in patients with alpha-synucleinopathies, with higher likelihood of developing RBD in male patients. However, RBD did not increase mortality risk within the cohort.
ANNALS OF NEUROLOGY
(2021)
Article
Clinical Neurology
Marcus O. Harrington, Jennifer E. Ashton, Hong-Viet V. Ngo, Scott A. Cairney
Summary: This study manipulated theta activity during sleep using auditory closed-loop stimulation, showing that stimulation led to a short-term increase in theta power followed by a prolonged suppression, as well as an increase in beta power. These results highlight the potential of auditory stimulation in investigating REM sleep electrophysiology and its impact on behavior.
Article
Physiology
Ian M. Greenlund, Carl A. Smoot, Jason R. Carter
Summary: The study found that men showed significantly greater blood pressure response following spontaneous K-complexes during sleep compared to women, indicating further differences in cardiovascular health between men and women.
JOURNAL OF APPLIED PHYSIOLOGY
(2021)
Article
Clinical Neurology
Carlos M. O. de Almeida, Manuelina M. C. Brito, Nayanne B. Bosaipo, Angela V. Pimentel, Vitor Tumas, Antonio W. Zuardi, Jose A. S. Crippa, Jaime E. C. Hallak, Alan L. Eckeli
Summary: This study evaluated the efficacy and safety of CBD as an alternative therapy for RBD in patients with Parkinson's disease. While CBD did not show significant differences compared to placebo for primary outcomes, there was a transient improvement in sleep satisfaction observed with a 300mg dose.
MOVEMENT DISORDERS
(2021)
Article
Clinical Neurology
Junjie Xu, Rui Zhou, Guodong Wang, Ying Guo, Xue Gao, Shuang Zhou, Chengyuan Ma, Lin Chen, Bihan Shi, Haiyan Wang, Fengchao Wang, Qinghua Liu
Summary: This study identified SLP-L and SLP-S isoforms as critical factors in the increase of sleep quantity and intensity in mice.
Article
Food Science & Technology
Min Young Um, Minseok Yoon, Jaekwang Lee, Jonghoon Jung, Suengmok Cho
Summary: The study found that turmeric has a sleep-promoting effect by reducing sleep latency and enhancing non-rapid eye movement sleep through H1R blockade. This mechanism was validated in experiments and may have potential clinical value for treating insomnia.
MOLECULAR NUTRITION & FOOD RESEARCH
(2021)
Article
Physiology
Evgeny Yu Bersenev, Yulia Ukraintseva, Gennadiy Kovrov, Yusef D. Yakhya, Galina Yu Vassilieva, Elena S. Tomilovskaya, Ilya Rukavishnikov, Sergey Posokhov, Artemiy Orlov, Nikolay Yu Osetsky, Oleg Orlov
Summary: During the 21-day Dry Immersion (DI), sleep architecture was significantly disturbed on the 3rd day, but returned to baseline values after the 10th day. An increase in REM duration on the 19th day and in recovery was accompanied by changes in nighttime heart rate and blood pressure parameters, suggesting regulatory changes in the cardiovascular system in response to environmental changes.
FRONTIERS IN PHYSIOLOGY
(2021)
Article
Biology
Manuel Spitschan, Nayantara Santhi, Amrita Ahluwalia, Dorothee Fischer, Lilian Hunt, Natasha A. Karp, Francis Levi, Ines Pineda-Torra, Parisa Vidafar, Rhiannon White
Summary: Growing evidence suggests that sex differences have a significant impact on various aspects of human biology. This review focuses on exploring the influence of sex on the circadian and sleep physiology of humans and identifies a data gap in investigating the non-visual effects of light. A virtual workshop on the biomedical implications of sex differences in sleep and circadian physiology highlights the need for inclusive and accessible research design, recruitment strategies to achieve a balanced sample size, utilization of data visualization to understand the influence of sex, statistical analyses that incorporate sex as a factor, and making participant-level data open for future meta-analytic efforts.
Article
Clinical Neurology
Julia E. Perkins, Annette Janzen, Felix P. Bernhard, Karen Wilhelm, Donald C. Brien, Jeff Huang, Brian C. Coe, David Vadasz, Geert Mayer, Douglas P. Munoz, Wolfgang H. Oertel
Summary: Patients with isolated REM Sleep Behavior Disorder (RBD) and Parkinson's disease (PD) show altered pupil and blink behavior compared to healthy controls. While RBD saccade parameters were similar to controls, suggesting that pupil and blink brain areas may be impacted before saccadic control areas, making them potential prodromal PD biomarkers.
MOVEMENT DISORDERS
(2021)
Article
Geriatrics & Gerontology
Chao Han, Jing An, Piu Chan
Summary: The study found that both pRBD and sleep insufficiency were independently associated with an increased risk of falls among the elderly population in China. When these two factors coexisted, the risk of falls increased less than expected, indicating a negative interaction between them.
Article
Psychology, Clinical
Elisabet Alzueta, Simon Podhajsky, Qingyu Zhao, Susan F. Tapert, Wesley K. Thompson, Massimiliano de Zambotti, Dilara Yuksel, Orsolya Kiss, Rena Wang, Laila Volpe, Devin Prouty, Ian M. Colrain, Duncan B. Clark, David B. Goldston, Kate B. Nooner, Michael D. De Bellis, Sandra A. Brown, Bonnie J. Nagel, Adolf Pfefferbaum, Edith Sullivan, Fiona C. Baker, Kilian M. Pohl
Summary: This study found that the COVID-19 pandemic has significantly increased the risk of depression in emerging adults, particularly young women. Frequent alcohol use and short sleep duration during the pandemic have been associated with an increase in depressive symptoms.
PSYCHOLOGICAL MEDICINE
(2023)
Article
Obstetrics & Gynecology
Elisabet Alzueta, Massimiliano de Zambotti, Harold Javitz, Teji Dulai, Benedetta Albinni, Katharine C. Simon, Negin Sattari, Jing Zhang, Alessandra Shuster, Sara C. Mednick, Fiona C. Baker
Summary: Using the Oura ring, this study tracked changes in sleep and related physiological features across the regular, healthy menstrual cycle of women. It found that objective and perceived measures of sleep and mood did not fluctuate significantly during the menstrual cycle, but other physiological changes in skin temperature and heart rate were evident.
INTERNATIONAL JOURNAL OF WOMENS HEALTH
(2022)
Article
Clinical Neurology
Fiona C. Baker, Kathryn Aldrich Lee
SLEEP MEDICINE CLINICS
(2022)
Article
Psychology, Clinical
William E. Pelham III, Dilara Yuksel, Susan F. Tapert, Fiona C. Baker, Kilian M. Pohl, Wesley K. Thompson, Simon Podhajsky, Chase Reuter, Qingyu Zhao, Sonja C. Eberson-Shumate, Duncan B. Clark, David B. Goldston, Kate B. Nooner, Sandra A. Brown
Summary: This study examined the impact of the COVID-19 pandemic on drinking and nicotine use in young adults and found that the pandemic had some short-term effects on drinking but had little effect on nicotine use.
ADDICTIVE BEHAVIORS
(2022)
Article
Health Care Sciences & Services
Edith Sullivan, Wesley K. Thompson, Ty Brumback, Devin Prouty, Susan F. Tapert, Sandra A. Brown, Michael D. De Bellis, Kate B. Nooner, Fiona C. Baker, Ian M. Colrain, Duncan B. Clark, Bonnie J. Nagel, Kilian M. Pohl, Adolf Pfefferbaum
Summary: This study found that testing experience has a significant impact on the measurement of trajectories in longitudinal studies. Learning has a major effect on accuracy and speed, while developmental effects on accuracy can be adequately described by linear fits and nonlinear fits for speed.
BMC MEDICAL RESEARCH METHODOLOGY
(2022)
Article
Psychology, Developmental
Jason M. Nagata, Jonathan Chu, Kyle T. Ganson, Stuart B. Murray, Puja Iyer, Kelley Pettee Gabriel, Andrea K. Garber, Kirsten Bibbins-Domingo, Fiona C. Baker
Summary: The study found that longer screen time each day was prospectively associated with higher prevalence of conduct and oppositional defiant disorder, with the strongest association found between social media use and conduct disorder.
JOURNAL OF CHILD PSYCHOLOGY AND PSYCHIATRY
(2023)
Article
Family Studies
Marybel R. Gonzalez, Sandra A. Brown, William E. Pelham, Susan F. Tapert, Stefanie C. Bodison, Connor McCabe, Fiona C. Baker, Arielle Baskin-Sommers, Anthony Steven Dick, Gayathri J. Dowling, Sabrina Gebreselassie, Mathieu Guillaume, Andrew T. Marshall, Chandni Sheth, Elizabeth R. Sowell, Amandine Van Rinsveld
Summary: During the COVID-19 pandemic, families faced unprecedented financial and social disruptions. The study found that poorer family well-being was linked to preexisting psychosocial and financial adversity, as well as pandemic-related material hardship and social disruptions. Parental alcohol use increased the risk of worsening family relationships, while better coping strategies were associated with overall better family well-being.
JOURNAL OF RESEARCH ON ADOLESCENCE
(2023)
Editorial Material
Endocrinology & Metabolism
Fiona C. Baker
JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM
(2023)
Letter
Clinical Neurology
Davide Benedetti, Luca Menghini, Raphael Vallat, Remington Mallett, Orsolya Kiss, Ugo Faraguna, Fiona C. Baker, Massimiliano de Zambotti
Article
Clinical Neurology
Luca Menghini, Dilara Yuksel, Devin Prouty, Fiona C. Baker, Christopher King, Massimiliano de Zambotti
Summary: This study characterized the daily patterns of sleep, stress, presleep worry, and mood in adolescents with and without insomnia symptomatology using wearable tracking and daily diary ratings. It was found that adolescents with insomnia reported higher levels of stress and worry, mainly related to school. Stress and worry predicted shorter sleep duration and earlier wake up times, which in turn predicted higher stress the following day. There was also a stronger effect of higher stress on sleep-time heart rate in adolescents with insomnia.
Article
Obstetrics & Gynecology
F. C. Baker
Summary: Women often experience sleep disturbances, especially night-time awakenings, during the transition to menopause and postmenopause. These disturbances can negatively impact daytime functioning, productivity, and mental and physical health. Management strategies include cognitive behavioral therapy for insomnia and hormone therapy.
Article
Clinical Neurology
Alessandra E. Shuster, Katharine C. Simon, Jing Zhang, Negin Sattari, Andres Pena, Elisabet Alzueta, Massimiliano de Zambotti, Fiona C. Baker, Sara C. Mednick
Summary: This study investigates the interaction between sleep and mood, considering menstrual cycle phase. The results show that subjective sleep quality and menstrual status interact to impact positive mood levels. Good sleep quality acts as a protective buffer to positive mood across the menstrual cycle.
Article
Substance Abuse
Jonatan Ottino-Gonzalez, Renata B. Cupertino, Zhipeng Cao, Sage Hahn, Devarshi Pancholi, Matthew D. Albaugh, Ty Brumback, Fiona C. Baker, Sandra A. Brown, Duncan B. Clark, Massimiliano de Zambotti, David B. Goldston, Beatriz Luna, Bonnie J. Nagel, Kate B. Nooner, Kilian M. Pohl, Susan F. Tapert, Wesley K. Thompson, Terry L. Jernigan, Patricia Conrod, Scott Mackey, Hugh Garavan
Summary: A distinct pattern of structural covariance networks (SCN) derived from MRI measurements of brain cortical thickness can be used to identify young adults with alcohol use disorder (AUD) and predict problematic drinking in adolescents. SCN can serve as a marker for brain-related psychopathology.
Article
Pediatrics
Jason M. Nagata, Nora Trompeter, Gurbinder Singh, Kyle T. Ganson, Alexander Testa, Dylan B. Jackson, Shervin Assari, Stuart B. Murray, Kirsten Bibbins-Domingo, Fiona C. Baker
Summary: This study aimed to investigate the prevalence and sociodemographic correlates of cyberbullying victimization and perpetration among 11-12-year-old early adolescents. The results showed that nearly one in 10 early adolescents reported cyberbullying victimization, with boys more likely to perpetrate cyberbullying but less likely to be victims compared to girls. Sexual minorities had higher odds of cyberbullying victimization, while lower household income was associated with higher odds of victimization. Total screen time, particularly on the internet and social media, was associated with both victimization and perpetration.
ACADEMIC PEDIATRICS
(2022)
Article
Health Care Sciences & Services
Massimiliano de Zambotti, Dilara Yuksel, Orsolya Kiss, Giacinto Barresi, Nicole Arra, Laila Volpe, Christopher King, Fiona C. Baker
Summary: This study describes a novel digital immersive virtual reality mind-body approach to reducing bedtime arousal in adolescents with insomnia. Preliminary data supports the effectiveness of this approach in regulating psychophysiological arousal levels by targeting neurocognitive and autonomic pathways.