期刊
JOURNAL OF RHEUMATOLOGY
卷 38, 期 8, 页码 1720-1727出版社
J RHEUMATOL PUBL CO
DOI: 10.3899/jrheum.110392
关键词
RESPONSE TO CHANGE; CLINICIANS; OUTCOMES; RESPONSIVENESS
类别
The OMERACT patient reported outcomes (PRO) working group evaluated the methodologies for measuring responsiveness to change at the Outcome Measures in Rheumatology (OMERACT) 10 meeting. The outcome measures used in PRO studies are often expressed as continuous data at the group level (e.g., mean change in pain on a 0-100 visual analog scale). This is difficult to interpret and cannot easily be translated to the individual level of response. When interpreting scores at the individual level, it is important to take into account the following 4 main concepts: (1) improvement; (2) status of well-being; (3) onset of action; and (4) sustainability. Information from clinical trials on how many patients showed a response, what the level of response was, and how many patients are doing well, would be extremely useful for physicians. The objective of this article is to outline how continuous data may be reported in a clinically relevant manner. We will describe 5 techniques of reporting continuous variables in clinical studies and discuss the relevance of each. (J Rheumatol 2011;38:1720-7; doi : 10.3899/jrheum.110392)
作者
我是这篇论文的作者
点击您的名字以认领此论文并将其添加到您的个人资料中。
推荐
暂无数据