Article
Integrative & Complementary Medicine
Cheng-Peng Sun, Zi-Li Jia, Xiao-Kui Huo, Xiang-Ge Tian, Lei Feng, Chao Wang, Bao-Jing Zhang, Wen-Yu Zhao, Xiao-Chi Ma
Summary: Inula, a genus of the Asteraceae, is rich in secondary metabolites with pharmacological activities, which have potential applications in drug development for various diseases. Recent researches from 2010 to 2020 have provided scientific basis and support for the utilization of Inula in new drug development.
AMERICAN JOURNAL OF CHINESE MEDICINE
(2021)
Review
Food Science & Technology
Da-Yong Zhou, Zi-Xuan Wu, Fa-Wen Yin, Shuang Song, Ao Li, Bei-Wei Zhu, Liang-Li (Lucy) Yu
Summary: This review discusses the structural modifications of chitosan to enhance its properties and the potential applications of chitosan and its derivatives in various health-related fields. The study also explores the potential of using chitosan in food systems to improve safety, quality, and health benefits while reducing environmental hazards.
ANNUAL REVIEW OF FOOD SCIENCE AND TECHNOLOGY, VOL 12, 2021
(2021)
Editorial Material
Biotechnology & Applied Microbiology
Christian Siadjeu, Boas Pucker
Summary: Recent advancements in plant genomics have allowed for a thorough exploration of the medicinal capabilities of plants by analyzing their gene repertoire. Comparative genomics and integration of transcriptomic data can reveal genes involved in biosynthesis pathways. Data-driven discovery of specialized metabolites has the potential to expedite research in this field.
Article
Food Science & Technology
Zhenguo Yan, Lihang Xie, Mengchen Li, Meng Yuan, Yao Tian, Daoyang Sun, Yanlong Zhang, Lixin Niu
Summary: The study measured the chemical composition, antioxidant, antibacterial, anticholinesterase, and antitumor activities of peony roots from different species and subspecies, showing the presence of various secondary metabolites and significant antioxidant and antibacterial effects. Paeoniflorin and paeonol were the highest content bioactive compounds found in the roots.
FOOD RESEARCH INTERNATIONAL
(2021)
Article
Food Science & Technology
Sneh Punia Bangar, Priyanka Kajla, Vandana Chaudhary, Nitya Sharma, Fatih Ozogul
Summary: Flavonoids, such as luteolin, are increasingly used in foods and active packaging systems for their functional properties and antimicrobial effects. Luteolin, a polyphenolic plant flavonoid, is naturally found as glycosides and can be converted into luteolin glucuronides in the intestine, which are responsible for its bioactivities. This review aims to compile important data on the biosynthesis, mechanism of action, bioactivities, bioavailability, and toxicity potential of luteolin.
Article
Agricultural Engineering
Pascual Garcia-Perez, Manuel Ayuso, Eva Lozano-Milo, Carla Pereira, Maria Ines Dias, Marija Ivanov, Ricardo C. Calhelha, Marina Sokovic, Isabel C. F. R. Ferreira, Lillian Barros, Pedro P. Gallego
Summary: This study utilized plant in vitro culture to investigate the phenolic compounds and associated bioactivities of Bryophyllum plants, finding that induction of nutritional stress can enhance the accumulation of phenolic compounds, especially flavonols and anthocyanins. The B. x houghtonii plant exhibited the highest antioxidant, cytotoxic, and anti-inflammatory activities, while B. daigremontianum showed effectiveness against various bacterial and fungal strains. The research aims to explore the phytochemical potential of this unexplored subgenus, suggesting Bryophyllum plants as a valuable source of bioactive compounds for food, cosmetic, and pharmaceutical industries.
INDUSTRIAL CROPS AND PRODUCTS
(2021)
Review
Biotechnology & Applied Microbiology
Peishan Li, Shufen He, Xuejiao Zhang, Qi Gao, Yanan Liu, Liwei Liu
Summary: Prodiginines are a diverse group of microbial secondary metabolites with various biological activities. Despite the focus on the star molecule prodigiosin, little is known about other prodiginine members, limiting their research and application. This review provides insights into the prodiginine family and serves as a guideline for new research.
APPLIED MICROBIOLOGY AND BIOTECHNOLOGY
(2022)
Article
Biochemistry & Molecular Biology
Mei-Jun Chu, Meng Li, Yongda Zhao
Summary: This review comprehensively summarizes 84 dimeric pyrrole-imidazole alkaloids (PIAs) discovered from 1981 to September 2022, including their source organisms, chemical structures, biological activities, and biosynthesis. The PIA dimers are classified and presented based on their carbon skeleton features and biosynthetic pathways. Additionally, relevant summaries of the source organisms and associated bioactivities of these compounds belonging to different chemical classes are provided, which will contribute to the understanding of the fascinating chemistry and biology of these unusual PIA dimers.
BIOORGANIC CHEMISTRY
(2023)
Review
Chemistry, Medicinal
Maan T. Khayat, Khadijah A. Mohammad, Abdelsattar M. Omar, Gamal A. Mohamed, Sabrin R. M. Ibrahim
Summary: This study compiles the reported bergamotane sesquiterpenoids from fungal sources from 1958 to June 2022, including a total of 97 compounds. Among these compounds, 38 were derived from fungi isolated from different marine sources. The study summarizes the biological activities, structural characterization, and biosynthesis of these compounds, providing insights for developing and discovering new valuable pharmaceutical agents.
Review
Biochemistry & Molecular Biology
Chu Wu, Yun Wang, Yujie Yang
Summary: This review focuses on the secondary metabolites and bioactivities of Pestalotiopsis species, collecting published articles from 2014 to 2021 and highlighting 239 new secondary metabolites. To date, 384 Pestalotiopsis species have been discovered, with the majority remaining unstudied. These species may contain secondary metabolites with unique bioactivities that could be beneficial in pharmacology.
Review
Biology
Ghosoon Albahri, Adnan Badran, Akram Hijazi, Anis Daou, Elias Baydoun, Mohamad Nasser, Othmane Merah
Summary: The skin protects the body from external damage and infections. Wound healing is a complex process involving various cellular activities. Natural plant-based medicines have been widely used for wound treatment and infection prevention, offering alternatives to antibiotic usage. This review focuses on commonly used medicinal plants from the Northern Hemisphere for wound care.
Review
Biochemistry & Molecular Biology
Mithun Rudrapal, Johra Khan, Abdul Aziz Bin Dukhyil, Randa Mohammed Ibrahim Ismail Alarousy, Emmanuel Ifeanyi Attah, Tripti Sharma, Shubham Jagdish Khairnar, Atul Rupchand Bendale
Summary: Chalcones are secondary metabolites found in edible and medicinal plants, with diverse pharmacological activities. Research on chalcones can provide a reliable platform for natural product-based drug discovery and promising drug candidates.
Review
Biochemistry & Molecular Biology
Rawan H. Hareeri, Mohammed M. Aldurdunji, Hossam M. Abdallah, Ali A. Alqarni, Shaimaa G. A. Mohamed, Gamal A. Mohamed, Sabrin R. M. Ibrahim
Summary: Aspergillus ochraceus is a fungus that has the ability to produce a wide range of biometabolites with diverse bioactivities. These metabolites have potential applications in various industries and biotechnological fields.
Review
Biotechnology & Applied Microbiology
Xin-Xin Kang, Shu-Lei Jia, Xin Wei, Mei Zhang, Guang-Lei Liu, Zhong Hu, Zhe Chi, Zhen-Ming Chi
Summary: Liamocins, glycolipids synthesized by Aureobasidium spp., show high bioactivity against pathogenic bacteria and cancer cells. Their biosynthesis involves multiple enzymes and genes, making them valuable in biotechnology applications across various sectors.
CRITICAL REVIEWS IN BIOTECHNOLOGY
(2022)
Article
Chemistry, Applied
Li-Na Zhao, Yu-Biao Cao, Qin Luo, Yong-Liang Xu, Na Li, Cheng-Xiao Wang, Jun-Wei Xu
Summary: In this study, a novel approach to enhance the production and bioactivities of Ganoderma exopolysaccharides was explored. The PMM1 gene was cloned and overexpressed in Ganoderma for the first time, leading to a significant increase in exopolysaccharide production. The transformed strain also exhibited stronger regulation effects on macrophage.
CARBOHYDRATE POLYMERS
(2022)