Article
Spectroscopy
Elliot J. Tay, Jonathan E. Barnsley, Daniel B. Thomas, Keith C. Gordon
Summary: Resonance Raman spectroscopy was used to identify and characterize psittacofulvins, showing different behaviors in red and yellow regions with Raman band wavenumber shifts. One yellow region exhibited similar characteristics to the red regions, suggesting the presence of psittacofulvins with greater conjugation.
SPECTROCHIMICA ACTA PART A-MOLECULAR AND BIOMOLECULAR SPECTROSCOPY
(2021)
Article
Chemistry, Analytical
Yeran Bai, Zhongyue Guo, Fatima C. Pereira, Michael Wagner, Ji-Xin Cheng
Summary: A mid-infrared photothermal-fluorescence in situ hybridization (MIP-FISH) platform is developed for simultaneous identification and metabolic analysis of microbes with single-cell resolution and high throughput. By improving MIP imaging, isotopically labeled compounds incorporated into proteins of individual bacterial cells can be sensitively detected, while FISH labeling with rRNA-targeted probes enables the identification of the analyzed cells. In proof-of-concept experiments, MIP-FISH successfully discriminates and identifies labeled bacterial cells within a complex human gut microbiome sample based on the clear spectral red shift in the protein amide I region caused by incorporation of 13C atoms from 13C-labeled glucose. This study opens up new opportunities for single-cell structure-function analyses in microbiology.
ANALYTICAL CHEMISTRY
(2023)
Article
Multidisciplinary Sciences
Andreij C. Gadelha, Douglas A. A. Ohlberg, Cassiano Rabelo, Eliel G. S. Neto, Thiago L. Vasconcelos, Joao L. Campos, Jessica S. Lemos, Vinicius Ornelas, Daniel Miranda, Rafael Nadas, Fabiano C. Santana, Kenji Watanabe, Takashi Taniguchi, Benoit van Troeye, Michael Lamparski, Vincent Meunier, Viet-Hung Nguyen, Dawid Paszko, Jean-Christophe Charlier, Leonardo C. Campos, Luiz G. Cancado, Gilberto Medeiros-Ribeiro, Ado Jorio
Summary: The twisted bilayer graphene undergoes self-organized lattice reconstruction, resulting in the formation of a superlattice that modulates vibrational and electronic structures, leading to phenomena such as strong correlations and superconductivity. Although experimental techniques and theoretical models face challenges in observing and describing these effects, nano-Raman spectroscopy can localize some vibrational modes and provide insights into the effects of electron-phonon coupling on the material properties.
Article
Materials Science, Multidisciplinary
Yusi Peng, Chenglong Lin, Yanyan Li, Yong Gao, Jing Wang, Jun He, Zhengren Huang, Jianjun Liu, Xiaoying Luo, Yong Yang
Summary: A highly sensitive semiconductor-based SERS substrate has been developed in this study, which can accurately identify the infectiousness of SARS-CoV-2 virions in actual environments through molecular enrichment and chemical enhancement effects.
Article
Biochemistry & Molecular Biology
Eric Boateng Osei, Liliia Paniushkina, Konrad Wilhelm, Juergen Popp, Irina Nazarenko, Christoph Krafft
Summary: Extracellular vesicles (EVs) ranging in size from 60 to 800 nm were isolated from plasma of control and prostate cancer patients using differential centrifugation and ultrafiltration techniques. Spontaneous Raman and surface-enhanced Raman spectroscopy (SERS) were employed to identify fractions that best discriminate between control and cancer patients, with results showing that EV12 and EV120 fractions provide the most effective separation.
Article
Chemistry, Multidisciplinary
Lanping Zeng, Weiying Song, Xiangfeng Jin, Quanfeng He, Lianhuan Han, Yuan-fei Wu, Corinne Lagrost, Yann Leroux, Philippe Hapiot, Yang Cao, Jun Cheng, Dongping Zhan
Summary: Single layer graphene (SLG) has excellent electron conductivity on its basal plane, but if its band gap could be opened and regulated controllably, it would behave as a semiconductor. By using scanning electrochemical microscopy, researchers demonstrated that electrochemically induced brominating addition reaction can open and regulate the band gap of SLG. This work provides a feasible and effective way to regulate the band gap of SLG, which would open new applications for SLG in micro-nano electronics and ultra-large-scale integrated circuits.
Article
Chemistry, Multidisciplinary
Robin R. Jones, Cornelia Miksch, Hyunah Kwon, Coosje Pothoven, Kristina R. Rusimova, Maarten Kamp, Kedong Gong, Liwu Zhang, Tim Batten, Brian Smith, Alejandro V. Silhanek, Peer Fischer, Daniel Wolverson, Ventsislav K. Valev
Summary: Against the backdrop of current healthcare and climate emergencies, surface enhanced Raman scattering (SERS) is gaining popularity as a technique for identifying and fingerprinting molecules in various substances. Researchers have investigated plasmonic nanohelices and found that they possess excellent SERS properties. These nanohelices can be produced at a low cost, exhibit strong and uniform Raman enhancement effects, and are anticipated to have broad applications in surface enhanced Raman spectroscopies and material science.
ADVANCED MATERIALS
(2023)
Article
Chemistry, Analytical
Xingkang Diao, Xinli Li, Shuping Hou, Haijuan Li, Guohua Qi, Yongdong Jin
Summary: Exosomes are promising noninvasive biomarkers for the early diagnosis and treatment of diseases, especially cancer. However, accurately distinguishing exosomes from clinical samples remains a challenge due to their heterogeneity. In this study, a machine learning-based label-free surface-enhanced Raman spectroscopy method was used to accurately identify exosomes in human serum samples for the diagnosis of breast cancer and cervical cancer.
ANALYTICAL CHEMISTRY
(2023)
Article
Chemistry, Analytical
Fanglan Yao, Pengcheng Xu, Hao Jia, Xinyu Li, Haitao Yu, Xinxin Li
Summary: The MEMS TGA technology utilizes temperature programming and microcantilever to achieve ultra-sensitive mass-loss analysis and high-efficiency rapid heating, meeting the higher requirements of TGA.
ANALYTICAL CHEMISTRY
(2022)
Article
Biochemistry & Molecular Biology
Michaela Matulova, Marek Bujdos, Marcel B. Miglierini, Martin Cesnek, Eva Duborska, Katarina Mosnackova, Hana Vojtkova, Tomas Kmjec, Julius Dekan, Peter Matus, Martin Urik
Summary: Iron-based nanomaterials have high technological impacts on environmental applications, particularly in wastewater treatment using the co-precipitation method. This research focused on the impact of selenium on the structure of iron nanomaterials, specifically in terms of their maturation and thermal transformation into hematite. The study found that selenium affected the structural order of precipitates initially, but crystal integrity and homogeneity increased consistently over time. The thermal transformation into well-crystallized hematite was more pronounced in the presence of selenite compared to selenate-treated and selenium-free samples.
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
(2021)
Article
Chemistry, Analytical
Xiaozhang Qu, Dan Sun, Yuqi Cheng, Jiafeng Wang, Yan Wang, Weiqing Xu, Guohua Qi, Shuping Xu
Summary: The study used smart nanoprobes to discriminate and monitor the dynamic expression of PD-L1, revealing rapid modulation of PD-L1 content on cell membranes under external electrostimulation. The findings suggest that external electrostimulation may offer a superior approach for regulating PD-L1 compared to chemical drugs, showing potential clinical application value. This versatile strategy could be applied to many membrane protein-related studies, providing a practical method for assessing molecular profiles of cell membrane proteins in response to external stimuli.
Review
Chemistry, Analytical
Wenqiang Pei, Rui Hu, Hao Liu, Le Wang, Yongchao Lai
Summary: An analytical method with high sensitivity and selectivity is needed to understand the impact of nanoplastics. This review article discusses the challenges in nanoplastic analysis using Raman spectroscopy and provides an overview of recent progress in this field. Various techniques, such as hyphenated technology and surface enhanced Raman spectroscopy, are highlighted for their efforts to improve the sensitivity, accuracy, and feasibility of Raman spectroscopy for nanoplastic analysis. The article concludes with a summary of current challenges and future research opportunities in advanced Raman spectroscopy for nanoplastic analysis.
TRAC-TRENDS IN ANALYTICAL CHEMISTRY
(2023)
Article
Biochemistry & Molecular Biology
Aristides Marcano Olaizola, Robinson Kuis, Anthony Johnson, David Kingsley
Summary: This study investigates the generation of singlet oxygen from dissolved oxygen in water and heavy water using Raman stimulation. Without singlet oxygen photosensitizers, nanosecond-pulsed visible blue laser light can produce a red Stokes peak that is oxygen-dependent. This peak is absent in the presence of an oxygen quencher, and the temporal photodepletion of uric acid absorbance peak supports singlet oxygen generation. The authors suggest a two-photon stimulated Raman process as the mechanism behind singlet oxygen production from dissolved O2 in the solvents.
JOURNAL OF PHOTOCHEMISTRY AND PHOTOBIOLOGY B-BIOLOGY
(2022)
Review
Health Care Sciences & Services
Charlotte Delrue, Marijn M. Speeckaert
Summary: Raman spectroscopy is a spectroscopic technique that can detect biochemical changes in biological samples at the molecular level, making it a valuable tool for disease diagnosis and prognosis. It offers several advantages over conventional methods.
JOURNAL OF PERSONALIZED MEDICINE
(2022)
Article
Engineering, Electrical & Electronic
Jorge A. Calderon, Heiddy P. Quiroz, M. Manso-Silvan, Alvaro Munoz Noval, A. Dussan, H. Mendez
Summary: The structural, morphological, topographical, and magnetic properties of GaSb/Mn multilayers deposited via DC magnetron sputtering at room temperature and 423 K were investigated in this study. The results showed the formation of p-type GaSb layers and effective interlayers due to the neighboring Mn layer. The multilayers exhibited a columnar microstructure and the grain sizes and roughness increased with the number of layers. Additionally, the formation of interlayers between GaSb and Mn layers was observed, which contributed to the magnetic behavior of the multilayers.
JOURNAL OF MATERIALS SCIENCE-MATERIALS IN ELECTRONICS
(2022)
