The role of the opioid system in alcohol dependence

Investigating expectation and reward in human opioid addiction with [11C]raclopride PET

(2013) Ben J. Watson et al.   ADDICTION BIOLOGY

A randomised, double-blind, placebo-controlled, efficacy study of nalmefene, as-needed use, in patients with alcohol dependence

(2013) Antoni Gual et al.   EUROPEAN NEUROPSYCHOPHARMACOLOGY

Dissociable Effects of Kappa-Opioid Receptor Activation on Impulsive Phenotypes in Wistar Rats

(2013) Brendan M Walker et al.   NEUROPSYCHOPHARMACOLOGY

The relationship between naloxone-induced cortisol and delta opioid receptor availability in mesolimbic structures is disrupted in alcohol-dependent subjects

(2012) Gary S. Wand et al.   ADDICTION BIOLOGY

Endogenous Opioid Release in the Human Brain Reward System Induced by Acute Amphetamine Administration

(2012) Alessandro Colasanti et al.   BIOLOGICAL PSYCHIATRY

Extending the Treatment Options in Alcohol Dependence: A Randomized Controlled Study of As-Needed Nalmefene

(2012) Karl Mann et al.   BIOLOGICAL PSYCHIATRY

Naltrexone for the Treatment of Alcoholism: Clinical Findings, Mechanisms of Action, and Pharmacogenetics

(2012) Lara Ray et al.   CNS & Neurological Disorders-Drug Targets

Alcohol Consumption Induces Endogenous Opioid Release in the Human Orbitofrontal Cortex and Nucleus Accumbens

(2012) J. M. Mitchell et al.   Science Translational Medicine

Increased ethanol intake in prodynorphin knockout mice is associated to changes in opioid receptor function and dopamine transmission

(2011) Teresa Femenía et al.   ADDICTION BIOLOGY

Different alcohol exposures induce selective alterations on the expression of dynorphin and nociceptin systems related genes in rat brain

(2011) Claudio D'Addario et al.   ADDICTION BIOLOGY

Prodynorphin CpG-SNPs associated with alcohol dependence: elevated methylation in the brain of human alcoholics

(2011) Malik Mumtaz Taqi et al.   ADDICTION BIOLOGY

The endogenous opioid system in human alcoholics: molecular adaptations in brain areas involved in cognitive control of addiction

(2011) Igor Bazov et al.   ADDICTION BIOLOGY

Ethanol as a Prodrug: Brain Metabolism of Ethanol Mediates its Reinforcing Effects

(2011) Eduardo Karahanian et al.   ALCOHOLISM-CLINICAL AND EXPERIMENTAL RESEARCH

Positron Emission Tomography Imaging of Mu- and Delta-Opioid Receptor Binding in Alcohol-Dependent and Healthy Control Subjects

(2011) Elise M. Weerts et al.   ALCOHOLISM-CLINICAL AND EXPERIMENTAL RESEARCH

Gabapentin Combined With Naltrexone for the Treatment of Alcohol Dependence

(2011) Raymond F. Anton et al.   AMERICAN JOURNAL OF PSYCHIATRY

Alcohol dependence, disinhibited behavior and variation in the prodynorphin gene

(2011) Janine D. Flory et al.   BIOLOGICAL PSYCHOLOGY

Genetic Vulnerability and Susceptibility to Substance Dependence

(2011) Laura Jean Bierut   NEURON

6β-Naltrexol, a Peripherally Selective Opioid Antagonist that Inhibits Morphine-Induced Slowing of Gastrointestinal Transit: An Exploratory Study

(2011) Janet Yancey-Wrona et al.   PAIN MEDICINE

Effect of Chronic Ethanol on Enkephalin in the Hypothalamus and Extra-Hypothalamic Areas

(2010) Guo-Qing Chang et al.   ALCOHOLISM-CLINICAL AND EXPERIMENTAL RESEARCH

Effects of the NOP receptor agonist Ro65-6570 on the acquisition of opiate- and psychostimulant-induced conditioned place preference in rats

(2010) Kris Rutten et al.   EUROPEAN JOURNAL OF PHARMACOLOGY

Preclinical evidence of new opioid modulators for the treatment of addiction

(2010) Marta Rodríguez-Arias et al.   EXPERT OPINION ON INVESTIGATIONAL DRUGS

In vivo characterization of the opioid antagonist nalmefene in mice

(2010) Melissa D. Osborn et al.   LIFE SCIENCES

The role of the dynorphin–κ opioid system in the reinforcing effects of drugs of abuse

(2010) Sunmee Wee et al.   PSYCHOPHARMACOLOGY

Biochemical and Neurotransmitter Changes Implicated in Alcohol-Induced Brain Damage in Chronic or 'Binge Drinking' Alcohol Abuse

(2009) R. J. Ward et al.   ALCOHOL AND ALCOHOLISM

kappa-Opioid receptor signaling and brain reward function

(2009) Adrie W. Bruijnzeel   BRAIN RESEARCH REVIEWS

Brain opioid receptor binding in early abstinence from alcohol dependence and relationship to craving: An [11C]diprenorphine PET study

(2009) Tim M. Williams et al.   EUROPEAN NEUROPSYCHOPHARMACOLOGY

Now or Later? An fMRI study of the effects of endogenous opioid blockade on a decision-making network

(2009) Charlotte A. Boettiger et al.   PHARMACOLOGY BIOCHEMISTRY AND BEHAVIOR

Reward Processing by the Opioid System in the Brain

(2009) Julie Le Merrer et al.   PHYSIOLOGICAL REVIEWS

Mu and Delta Opioid Receptors Oppositely Regulate Motor Impulsivity in the Signaled Nose Poke Task

(2009) Mary C. Olmstead et al.   PLoS One

Genetic approaches to addiction: genes and alcohol

(2008) Francesca Ducci et al.   ADDICTION

Acamprosate: Recent Findings and Future Research Directions

(2008) Karl Mann et al.   ALCOHOLISM-CLINICAL AND EXPERIMENTAL RESEARCH

Alcohol and opioid dependence medications: Prescription trends, overall and by physician specialty

(2008) Tami L. Mark et al.   DRUG AND ALCOHOL DEPENDENCE

Activation of kappa opioid receptors decreases synaptic transmission and inhibits long-term potentiation in the basolateral amygdala of the mouse

(2008) Volker Huge et al.   EUROPEAN JOURNAL OF PAIN

Acute and chronic heroin dependence in mice: Contribution of opioid and excitatory amino acid receptors

(2008) Gad Klein et al.   EUROPEAN JOURNAL OF PHARMACOLOGY

Regarding “Dynorphin is a downstream effector of striatal BDNF regulation of ethanol intake”

(2008) Brendan M. Walker et al.   FASEB JOURNAL

Ethanol dually modulates GABAergic synaptic transmission onto dopaminergic neurons in ventral tegmental area: Role of μ-opioid receptors

(2008) C. Xiao et al.   NEUROSCIENCE

Effects of acute ethanol on opioid peptide release in the central amygdala: an in vivo microdialysis study

(2008) Minh P. Lam et al.   PSYCHOPHARMACOLOGY