Orexin receptor antagonism: an ascending multiple-dose study with almorexant

Orexin Receptor Antagonism, a New Sleep-Enabling Paradigm: A Proof-of-Concept Clinical Trial

(2012) P Hoever et al.   CLINICAL PHARMACOLOGY & THERAPEUTICS

Absolute Oral Bioavailability of Almorexant, a Dual Orexin Receptor Antagonist, in Healthy Human Subjects

(2012) Matthias Hoch et al.   PHARMACOLOGY

Pharmacokinetics and Tolerability of Almorexant in Japanese and Caucasian Healthy Male Subjects

(2011) Matthias Hoch et al.   PHARMACOLOGY

Orexin Receptor Antagonism, a New Sleep-Promoting Paradigm: An Ascending Single-Dose Study With Almorexant

(2010) P Hoever et al.   CLINICAL PHARMACOLOGY & THERAPEUTICS

Food Effect and Biocomparison of Two Formulations of the Dual Orexin Receptor Antagonist Almorexant in Healthy Male Subjects

(2010) Matthias Hoch et al.   JOURNAL OF CLINICAL PHARMACOLOGY

Orexin/Hypocretin: A Neuropeptide at the Interface of Sleep, Energy Homeostasis, and Reward System

(2009) N. Tsujino et al.   PHARMACOLOGICAL REVIEWS

The influence of circadian rhythms on the kinetics of drugs in humans

(2008) Massimo Baraldo   Expert Opinion on Drug Metabolism & Toxicology

The pharmacokinetic and pharmacodynamic effects of SL65.1498, a GABA-A 2,3 selective agonist, in comparison with lorazepam in healthy volunteers

(2008) SL de Haas et al.   JOURNAL OF PSYCHOPHARMACOLOGY

Emerging anti-insomnia drugs: tackling sleeplessness and the quality of wake time

(2008) Keith A. Wafford et al.   NATURE REVIEWS DRUG DISCOVERY