Article
Multidisciplinary Sciences
Hsin-Yi Fan, Cheuk-Kwan Sun, Yu-Shian Cheng, Weilun Chung, Ruu-Fen Tzang, Hsien-Jane Chiu, Chun-Ning Ho, Kuo-Chuan Hung
Summary: This study provides a systematic review and analysis of the effectiveness of electroencephalogram-based neurofeedback (EEG-NF) in treating the core symptoms of attention-deficit hyperactivity disorder (ADHD) in adolescents/adults. The results suggest that EEG-NF can effectively improve inattention symptoms, but its effectiveness in reducing hyperactivity/impulsivity remains inconclusive.
SCIENTIFIC REPORTS
(2022)
Review
Behavioral Sciences
Sara Carucci, Carla Balia, Antonella Gagliano, Angelico Lampis, Jan K. Buitelaar, Marina Danckaerts, Ralf W. Dittmann, Peter Garas, Chris Hollis, Sarah Inglis, Kerstin Konrad, Hanna Kovshoff, Elizabeth B. Liddle, Suzanne McCarthy, Peter Nagy, Pietro Panei, Roberta Romaniello, Tatiana Usala, Ian C. K. Wong, Tobias Banaschewski, Edmund Sonuga-Barke, David Coghill, Alessandro Zuddas
Summary: The study reviewed the association of long-term MPH exposure with height, weight, and timing of puberty in ADHD individuals. MPH was found to have consistent significant effects on reducing height and weight, with more prominent impacts observed in the initial months of treatment. Limited data were available on the timing of puberty. Prospective studies are needed to further explore the underlying biological mechanisms and potential clinical implications.
NEUROSCIENCE AND BIOBEHAVIORAL REVIEWS
(2021)
Review
Biochemistry & Molecular Biology
E. M. Bruxel, C. R. Moreira-Maia, G. C. Akutagava-Martins, T. P. Quinn, M. Klein, B. Franke, M. Ribases, P. Rovira, C. Sanchez-Mora, D. B. Kappel, N. R. Mota, E. H. Grevet, C. H. D. Bau, M. Arcos-Burgos, L. A. Rohde, M. H. Hutz
Summary: This study conducted a meta-analysis to investigate the association between ADGRL3 gene variants and ADHD susceptibility in children and adults, finding significant correlation in children but not in adults. The results suggest that ADGRL3 gene is predominantly associated with childhood ADHD.
MOLECULAR PSYCHIATRY
(2021)
Review
Medicine, General & Internal
Danfeng Yuan, Manxue Zhang, Yan Huang, Xinwei Wang, Jian Jiao, Yi Huang
Summary: This meta-analysis suggests that noradrenergic gene polymorphisms may impact the efficacy of methylphenidate (MPH) in children with attention-deficit hyperactivity disorder (ADHD). Specifically, the NET rs28386840 is associated with improved MPH response, while the ADRA2A MspI is linked to improvements in inattention symptoms. Further research with larger sample sizes is needed to validate these findings.
Article
Pediatrics
Li-Fan Pai, Der-Shiun Wang, Wan-Fu Hsu, Shao-Wei Huang, Chi-Hsiang Chung, Shyi-Jou Chen, Wu-Chien Chien, Der-Ming Chu
Summary: This study found that children with ADHD have a higher risk of central precocious puberty. Early referral to a pediatric endocrinologist for evaluation can lead to correct diagnosis. Early intervention treatment with gonadotropin-releasing hormone agonist may improve final height in children with central precocious puberty.
PEDIATRIC RESEARCH
(2022)
Review
Multidisciplinary Sciences
Jung Tae Kim, Kibong Kim, Lin Ang, Hye Won Lee, Jun-Yong Choi, Myeong Soo Lee
Summary: This article describes a systematic review that aims to evaluate the effectiveness of acupuncture as a treatment for ADHD. The study will conduct literature searches in multiple databases and analyze the selected studies using the Cochrane Risk of Bias Assessment Tool. The findings of this review will be used to support relevant health policies and practices.
Review
Clinical Neurology
Shun Wang, Baozhen Yao, Haiju Zhang, Liping Xia, Shiqian Yu, Xia Peng, Dan Xiang, Zhongchun Liu
Summary: Epilepsy and attention-deficit/hyperactivity disorder (ADHD) are common neurological and neuropsychiatric disorders, and they can coexist. However, the degree of comorbidity between both disorders has never been quantified. A meta-analysis of 63 studies with over 1 million individuals from 17 countries revealed that the pooled prevalence of ADHD in epilepsy was 22.3%, while the pooled prevalence of epilepsy in ADHD was 3.4%. Factors such as sample size, specification, geographical variations, and diagnostic methods contributed to the observed heterogeneity in comorbidity rates. Further research is needed to understand the underlying mechanisms.
JOURNAL OF NEUROLOGY
(2023)
Article
Multidisciplinary Sciences
Amy M. Ni, Brittany S. Bowes, Douglas A. Ruff, Marlene R. Cohen
Summary: Most systems neuroscience studies can be categorized into basic science work and translational work. This study combines these two approaches and reveals that orally administered methylphenidate enhances spatially selective visual attention and improves visual performance. Furthermore, it suggests that decreased correlated variability of neurons may be a general mechanism for treating neuropsychiatric disorders.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
(2022)
Article
Psychiatry
Dara E. Babinski, Erika F. H. Saunders, Fan He, Duanping Liao, Amanda M. Pearl, Daniel A. Waschbusch
Summary: This study examined the diagnostic indicators, clinical characteristics, and functional impairment associated with adult ADHD using electronic medical records and self-report measures. The results showed a significant difference in prevalence of ADHD between self-report screening and medical records. ADHD was found to contribute to functional impairment even when controlling for other psychiatric comorbidities.
PSYCHIATRY RESEARCH
(2022)
Article
Biochemistry & Molecular Biology
Eliane S. Sanches, Raquel Boia, Ricardo A. Leitao, Maria H. Madeira, Carlos A. Fontes-Ribeiro, Antonio Francisco Ambrosio, Rosa Fernandes, Ana Paula Silva
Summary: Attention-Deficit/Hyperactivity Disorder (ADHD) is a common neurodevelopmental disorder that affects children, and it is associated with ophthalmologic abnormalities. The effects of methylphenidate (MPH) on retinal physiology in ADHD are still unclear. This study used animal models to investigate the structural, functional, and cellular alterations in the retina of ADHD, as well as the impact of MPH. The findings revealed deficits in retinal structure, function, and neurons in the ADHD animal model, and MPH had a beneficial effect on reducing inflammation and blood-retinal barrier dysfunction. However, MPH had opposite effects in the control animals, impairing retinal function and promoting inflammation.
Article
Psychology, Developmental
Kelsey K. Wiggs, Rosanna Breaux, Joshua M. Langberg, James L. Peugh, Stephen P. Becker
Summary: This study examines the sleep differences in adolescents with ADHD who use stimulant medication. The findings suggest that stimulant treatment does not significantly affect the sleep of adolescents with ADHD.
EUROPEAN CHILD & ADOLESCENT PSYCHIATRY
(2023)
Article
Multidisciplinary Sciences
Sneha M. Vaddadi, Nicholas J. Czelatka, Belsy D. Gutierrez, Bhumika C. Maddineni, Kenneth L. McCall, Brian J. Piper
Summary: In recent years, the use of prescription stimulants in the United States has been increasing, particularly for amphetamine and lisdexamfetamine. The study found that the usage of stimulants in the Western region was lower compared to other regions, and areas with a higher percentage of Hispanic populations also had lower stimulant usage.
Review
Psychology, Developmental
Khanh Linh Duong, Bo Ram Yang, Hwi-Yeol Yun, Jung-Woo Chae
Summary: This PRISMA meta-analysis aimed to determine the effect of MPH on height in children/adolescents with ADHD and its predictive factors. The study found a significant reduction in height after MPH treatment, with high heterogeneity. Factors such as study region, ADHD subtype, and patient's stimulant-naive status at baseline may modify the effect on height. Clinicians should consider the negative effect of MPH on height in ADHD patients and further well-designed longitudinal studies are needed.
EUROPEAN CHILD & ADOLESCENT PSYCHIATRY
(2023)
Article
Biochemistry & Molecular Biology
Aurina Arnatkeviciute, Mathieu Lemire, Claire Morrison, Michael Mooney, Peter Ryabinin, Nicole M. Roslin, Molly Nikolas, James Coxon, Jeggan Tiego, Ziarih Hawi, Alex Fornito, Walter Henrik, Jean-Luc Martinot, Marie-Laure Paillere Martinot, Eric Artiges, Hugh Garavan, Joel Nigg, Naomi P. Friedman, Christie Burton, Russell Schachar, Jennifer Crosbie, Mark A. Bellgrove
Summary: Deficits in effective executive function are associated with psychiatric disorders and impact everyday functioning. The genetic architecture of these traits is not well understood. This study identified genetic influences on inhibitory control using a genome wide association study, but larger sample sizes are needed for more robust associations. The results also support the use of executive function measures as endophenotypes for neuropsychiatric disorders.
MOLECULAR PSYCHIATRY
(2023)
Article
Clinical Neurology
Tien-Wei Hsu, Mu-Hong Chen, Che-Sheng Chu, Shih-Jen Tsai, Ya-Mei Bai, Tung-Ping Su, Tzeng-Ji Chen, Chih-Sung Liang
Summary: This study found that children, adolescents, and young adults with ADHD have a higher risk of migraine, and the risk is not associated with the dosage of ADHD medications.
Article
Psychiatry
Gabriele Gaigl, Esther Taeumer, Andreas Allgoewer, Thomas Becker, Johanna Breilmann, Peter Falkai, Uta Guehne, Reinhold Kilian, Steffi G. Riedel-Heller, Klemens Ajayi, Jessica Baumgaertner, Peter Brieger, Karel Frasch, Stephan Heres, Markus Jaeger, Andreas Kuethmann, Albert Putzhammer, Bertram Schneeweiss, Michael Schwarz, Markus Koesters, Alkomiet Hasan
Summary: Migration rates globally are increasing, leading to a need for national mental health services to adapt to the needs of individuals with migration backgrounds. This study found that compared to non-migrant patients, those with migration backgrounds were more satisfied with their overall treatment. However, there were no differences between the two groups in terms of treatment needs and utilization of mental health services.
Article
Psychiatry
Ceren Acarturk, Ersin Uygun, Zeynep Ilkkursun, Kenneth Carswell, Federico Tedeschi, Mine Batu, Sevde Eskici, Gulsah Kurt, Minna Anttila, Teresa Au, Josef Baumgartner, Rachel Churchill, Pim Cuijpers, Thomas Becker, Markus Koesters, Tella Lantta, Michela Nose, Giovanni Ostuzzi, Mariana Popa, Marianna Purgato, Marit Sijbrandij, Giulia Turrini, Maritta Valimaki, Lauren Walker, Johannes Wancata, Elisa Zanini, Ross G. White, Mark van Ommeren, Corrado Barbui
Summary: This study assessed the effectiveness of a self-help psychological intervention called Self-Help Plus in preventing the development of mental disorders among Syrian refugees in Turkey. The results showed that participants in the Self-Help Plus group were less likely to have any mental disorders at six-month follow-up compared to the control group. Furthermore, Self-Help Plus was associated with beneficial effects on symptoms of depression, personally identified psychological outcomes, and quality of life.
Article
Public, Environmental & Occupational Health
Uta Guehne, Alexander Pabst, Markus Koesters, Alkomiet Hasan, Peter Falkai, Reinhold Kilian, Andreas Allgoewer, Klemens Ajayi, Jessica Baumgaertner, Peter Brieger, Karel Frasch, Stephan Heres, Markus Jaeger, Andreas Kuethmann, Albert Putzhammer, Bertram Schneeweiss, Michael Schwarz, Thomas Becker, Johanna Breilmann, Steffi G. Riedel-Heller
Summary: The study reveals a high risk of exclusion from competitive employment among individuals with severe mental illness, yet a significant proportion are employed. Efforts are needed to enhance workforce participation by improving physical health and strengthening psychosocial functioning.
JOURNAL OF OCCUPATIONAL MEDICINE AND TOXICOLOGY
(2022)
Article
Psychiatry
Christian Goetzl, Tobias Staiger, Maja Stiawa, Petra Beschoner, Harald Gundel, Thomas Becker, Reinhold Kilian, Silvia Krumm
Summary: The study found that fathers with depression often adopt coping strategies that are independent of their families, but in reality, they need more familial support and consideration of family needs.
PSYCHIATRISCHE PRAXIS
(2022)
Article
Environmental Sciences
Annabel Sandra Mueller-Stierlin, Uemmueguelsuem Dinc, Katrin Herder, Julia Walendzik, Matthias Schuetzwohl, Thomas Becker, Reinhold Kilian
Summary: This study analyzed the cost-effectiveness of providing NWpG mental health care packages plus treatment as usual (NWpG) compared to treatment as usual alone (TAU) in Germany. The results showed no significant differences in costs and quality-adjusted life-years between the NWpG and TAU groups, and the probability of NWpG being cost-effective was estimated to be less than 75%.
INTERNATIONAL JOURNAL OF ENVIRONMENTAL RESEARCH AND PUBLIC HEALTH
(2022)
Article
Clinical Neurology
Daniel Richter, Steffi Riedel-Heller, Johanna Breilmann, Alkomiet Hasan, Peter Falkai, Reinhold Kilian, Andreas Allgoewer, Klemens Ajayi, Jessica Baumgaertner, Peter Brieger, Karel Frasch, Stephan Heres, Markus Jaeger, Andreas Kuethmann, Albert Putzhammer, Bertram Schneeweiss, Michael Schwarz, Thomas Becker, Markus Koesters, Uta Guehne
Summary: This study assessed the experiences and attitudes towards exercise therapy in individuals with severe mental illness (SMI) and found that the majority of patients had a high preference for exercise therapy. Higher values in the GAF assessment and living in a metropolitan area predicted a high preference for exercise therapy among patients with severe mental illness.
FORTSCHRITTE DER NEUROLOGIE PSYCHIATRIE
(2023)
Editorial Material
Psychiatry
Uta Guehne, Stefan Weinmann, Thomas Becker, Steffi G. Riedel-Heller
PSYCHIATRISCHE PRAXIS
(2022)
Article
Psychiatry
Britta Reinke, Candelaria Mahlke, Christina Botros, Alexa Klaering, Martin Lambert, Anne Karow, Juergen Gallinat, Antonia Zapf, Ann-Kathrin Ozga, Alexandra Hoeller, Nadia Bustami, Jens Reimer, Jenny Ludtke, Oliver Schaper, Martin Lison, Andreas Bechdolf, Johanna Baumgardt, Jennifer Spiegel, Olaf Hardt, Sandeep Rout, Sonja Memarzadeh, Sebastian von Peter, Julian Schwarz, Claudia Langer, Sabine Glotz, Karel Frasch, Nicolas Ruesch, Ulf Kuenstler, Thomas Bock, Thomas Becker
Summary: The study investigates the combination of home treatment (HT) and peer support (PS) for patients with severe mental illness (SMI). The randomized controlled trial compares the effects of HT with and without PS on relapse/prevention of recurrence, disease severity, general functioning, self-efficacy, psychosocial health, stigma resistance, recovery support, and service satisfaction. The study aims to provide further evidence for the efficacy of PS and promote its implementation in psychiatric settings.
Article
Multidisciplinary Sciences
Annabel Sandra Mueller-Stierlin, Friedrich Meixner, Jutta Lehle, Anne Kohlmann, Mara Schumacher, Stefanie Woehler, Anke Haensel, Sabrina Reuter, Katrin Herder, Nicole Bias, Thomas Becker, Reinhold Kilian
Summary: The study investigates the role of perceived empowerment (PE) in preventing negative effects of the COVID-19 pandemic on daily living for individuals with severe mental illness (SMI). The results show that negative effects increase with illness-related impairment but decrease with higher levels of PE. PE is negatively associated with the negative impact of the pandemic and positively associated with quality of life.
Article
Environmental Sciences
Moritz E. Wigand, Cristian Timmermann, Ansgar Scherp, Thomas Becker, Florian Steger
Summary: Climate change, pollution, and deforestation have a negative impact on global mental health. Wealthy individuals and high-income countries contribute the most to these environmental issues, while poor individuals and low-income countries are heavily affected. Research on the link between mental health and the environment is growing, with a focus on topics such as climate change, chemical pollution, and neurobiological effects. However, social and ethical aspects of the climate change-mental health link have been neglected and require further research.
Article
Psychiatry
Oxana Kosenko, Karl Bechter, Thomas Becker, Florian Steger
Summary: Gerd Huber was an influential West German psychiatrist and neurologist of the postwar period, known for his significant contributions to the research of schizophrenia. The Huber Archive, containing his personal and professional papers, is of great importance for studying the history of psychiatry in postwar West Germany, the development of concepts in schizophrenia research and biological psychiatry, and other related topics.
PSYCHIATRISCHE PRAXIS
(2023)
Article
Psychiatry
Thomas Becker, Georg Schomerus, Sven Speerforck
Summary: This article discusses the mental health reform processes in Great Britain and Italy, comparing their similarities and differences, and proposes a social history framework to understand these reform processes as part of societal development.
PSYCHIATRISCHE PRAXIS
(2023)
Article
Psychiatry
Leonie Ascone, Anja Christine Rohenkohl, Rene Hurlemann, Eva Meisenzahl, Steffi G. Riedel-Heller, Thomas Becker, Malek Bajbouj, Marie von Lilienfeld-Toal, Jurgen Gallinat, Martin Lambert
Summary: This essay proposes a matrix to visualize the indirect consequences of the pandemic, which include costs, morbidity, and mortality, compared to the direct effects of SARS-CoV-2. By using this matrix, virus-related and psychosocial risks for different populations can be assessed in a systematic and concise manner. The theoretical and empirical basis of COVID-19-related and psychosocial vulnerability, stressors, and consequences are derived, with an exemplary quantification of the matrix showing a high risk for severe COVID-19 consequences and pronounced psychosocial collateral effects for the vulnerable group of people with severe mental illness. This proposed approach could be further discussed for risk-graded pandemic management, crisis recovery, and future preparedness to address psychosocial collateral effects and protect vulnerable groups.
PSYCHIATRISCHE PRAXIS
(2023)
Article
Psychiatry
Sarah Fritz, Markus Koesters, Andreas Allgoewer, Thomas Becker, Reinhold Kilian, Uta Guehne, Steffi G. Riedel-Heller, Alkomiet Hasan, Peter Falkai, Klemens Ajayi, Jessica Baumgaertner, Peter Brieger, Karel Frasch, Stephan Heres, Markus Jaeger, Andreas Kuethmann, Albert Putzhammer, Bertram Schneeweiss, Michael Schwarz, Johanna Breilmann
Summary: The influence of guideline recommendations and other factors on the utilization of psychosocial interventions in people with severe mental illness was examined. Patients are less likely to receive therapies with a strong recommendation compared to other levels of recommendation. Various other factors are diffusely associated with utilization rates, but no ubiquitous predictors could be identified across all therapies.
PSYCHIATRISCHE PRAXIS
(2023)
Article
Surgery
Felix Nickel, Marius Distler, Eldridge F. Limen, Philipp A. Wise, Karl-Friedrich Kowalewski, Patricia M. Tritarelli, Daniel Perez, Jakob R. Izbicki, Jan-Niclas Kersebaum, Jan-Hendrik Egberts, Thomas Becker, Lea Timmermann, Thomas Malinka, Marcus Bahra, Johann Pratschke, Beat P. Mueller-Stich, Juergen Weitz, Thilo Hackert
BRITISH JOURNAL OF SURGERY
(2023)