Article
Clinical Neurology
Tamara Pringsheim, Christos Ganos, Christelle Nilles, Andrea E. E. Cavanna, Donald L. L. Gilbert, Erica Greenberg, Andreas Hartmann, Tammy Hedderly, Isobel Heyman, Holan Liang, Irene Malaty, Osman Malik, Nanette Mol Debes, Kirsten Muller Vahl, Alexander Munchau, Tara Murphy, Peter Nagy, Tamsin Owen, Renata Rizzo, Liselotte Skov, Jeremy Stern, Natalia Szejko, Yulia Worbe, Davide Martino
Summary: In 2020, there was a significant increase in referrals for young people with rapid onset of severe tic-like behaviors. A working group was formed to develop clinical criteria for the diagnosis of functional tic-like behaviors (FTLBs) to aid in recognition and diagnosis by healthcare professionals.
EUROPEAN JOURNAL OF NEUROLOGY
(2023)
Article
Psychiatry
Wen Xu, Qiang Ding, Ying Zhao, Wenqing Jiang, Jingjing Han, Jinhua Sun
Summary: The objective of this study was to investigate the adaptability of Comprehensive Behavioral Intervention for Tics (CBIT) for a Chinese population, and to evaluate the efficacy of combined CBIT and pharmacotherapy (CBIT + PT) compared to CBIT or pharmacotherapy (PT) alone for reducing tics and improving the quality of life (QoL) in Chinese children with chronic tic disorders (CTD) and Tourette syndrome (TS). The results showed that CBIT was effective in reducing tic severity in Chinese children with tic disorders, but CBIT + PT may not be superior to CBIT alone in reducing tic severity and improving quality of life.
FRONTIERS IN PSYCHIATRY
(2022)
Article
Clinical Neurology
Simon Morand-Beaulieu, Michael J. Crowley, Heidi Grantz, James F. Leckman, Lawrence Scahill, Denis G. Sukhodolsky
Summary: Comprehensive Behavioral Intervention for Tics (CBIT) is an effective treatment for Tourette syndrome (TS), but its underlying brain mechanisms are not well understood. This study found no association between EEG coherence during a Go/NoGo task and CBIT outcome, suggesting that the brain processes involved in motor response inhibition may not play a role in CBIT.
CLINICAL NEUROPHYSIOLOGY
(2022)
Article
Medicine, General & Internal
Martina Haas, Ewgeni Jakubovski, Katja Kunert, Carolin Fremer, Nadine Buddensiek, Sebastian Haeckl, Martina Lenz-Ziegenbein, Richard Musil, Veit Roessner, Alexander Muenchau, Irene Neuner, Armin Koch, Kirsten Mueller-Vahl
Summary: Comprehensive Behavioral Intervention for Tics (CBIT) is a first-line therapy for tics, but its availability is limited due to a lack of qualified therapists. This study suggests that internet-delivered, therapist-independent CBIT intervention (iCBIT) is superior to placebo in treating tics, and the treatment effects of iCBIT even increase over time.
JOURNAL OF CLINICAL MEDICINE
(2022)
Review
Medicine, General & Internal
Irene A. Malaty, Seonaid Anderson, Shannon M. Bennett, Cathy L. Budman, Barbara J. Coffey, Keith A. Coffman, Erica Greenberg, Joseph F. McGuire, Kirsten R. Mueller-Vahl, Michael S. Okun, Julio Quezada, Amy Robichaux-Viehoever, Kevin J. Black
Summary: A global phenomenon characterized by sudden onset and rapid escalation of tics and tic-like movements and phonations has emerged in the past 3 years. It has been observed not only in youth known to have tics or Tourette syndrome, but also in those with no prior history of tics.
JOURNAL OF CLINICAL MEDICINE
(2022)
Article
Psychology, Developmental
Noa Gur, Sharon Zimmerman-Brenner, Aviva Fattal-Valevski, Michael Rotstein, Tammy Pilowsky Peleg
Summary: There is increasing evidence suggesting that behavioral techniques, such as Comprehensive Behavioral Intervention for Tics (CBIT), are effective in managing tics in youth with Tourette syndrome and tics disorders (TDs). This study aimed to explore the contribution of CBIT to cognitive inhibition and emotion regulation beyond tic control. The findings revealed that following CBIT intervention, cognitive inhibition and cognitive reappraisal significantly increased. These results suggest that CBIT may have a broader impact on improving cognitive and emotional regulation abilities.
EUROPEAN CHILD & ADOLESCENT PSYCHIATRY
(2023)
Article
Clinical Neurology
Karla Claudio-Campos, Daniel Stevens, Sang-Wahn Koo, Alexa Valko, Oscar Joseph Bienvenu, Cathy B. Budman, Danielle C. Cath, Sabrina Darrow, Daniel Geller, Fernando S. Goes, Marco A. Grados, Benjamin D. Greenberg, Erica Greenberg, Matthew E. Hirschtritt, Cornelia Illmann, Franjo Ivankovic, Robert A. King, James A. Knowles, Janice Krasnow, Paul C. Lee, Gholson J. Lyon, James T. McCracken, Mary M. Robertson, Lisa Osiecki, Mark A. Riddle, Guy Rouleau, Paul Sandor, Gerald Nestadt, Jack Samuels, Jeremiah M. Scharf, Carol A. Mathews
Summary: In individuals with Persistent motor or vocal tic disorder (PMVT) and Tourette syndrome (TS), there are differences in comorbid psychiatric disorders, age of tic onset, and tic severity. ADHD and OCD increase the odds of other psychiatric disorders, contributing to the observed differences between PMVT and TS. First-degree relatives of TS patients have elevated rates of TS, PMVT, OCD, and ADHD compared to the general population.
MOVEMENT DISORDERS
(2021)
Article
Clinical Neurology
Stephanie Cernera, Leena Pramanik, Zachary Boogaart, Jackson N. Cagle, Julieth Gomez, Katie Moore, Ka Loong Kelvin Au, Michael S. Okun, Aysegul Gunduz, Wissam Deeb
Summary: This study aimed to develop a sensor-based paradigm to detect and classify tics in Tourette syndrome. The results demonstrate that wearable sensors can capture physiological differences between tic and voluntary movements and are comparable to expert consensus. This has significant implications for individualizing and improving care for people with TS.
CLINICAL NEUROPHYSIOLOGY
(2022)
Article
Clinical Neurology
Jose Fidel Baizabal-Carvallo, Marlene Alonso-Juarez, Joseph Jankovic
Summary: Tics are rapid, recurrent, non-rhythmic movements or emitted sounds. This study compared tics associated with Tourette syndrome (TS) and secondary tic disorders (STD). It found that patients with TS had a younger age at onset, more severe and complex tics, and involvement of cranial-cervical muscles. Simple phonic tics showed the highest diagnostic accuracy for TS, but there was overlap in tic types and comorbidities between TS and STD patients.
JOURNAL OF NEURAL TRANSMISSION
(2023)
Article
Psychiatry
Takeshi Inoue, Kohei Togashi, Jumpei Iwanami, Douglas W. Woods, Ryoichi Sakuta
Summary: This study assessed the preliminary efficacy, feasibility, and acceptability of remotely administered group comprehensive behavioral intervention for tics (RG-CBIT) in Japan. The results showed that RG-CBIT had satisfactory outcomes in reducing tic severity, as well as high attendance rates and favorable process measurement scores.
FRONTIERS IN PSYCHIATRY
(2022)
Review
Medicine, General & Internal
Keisuke Ueda, Kevin J. Black
Summary: Tics, characterized by sudden, rapid, nonrhythmic movements or vocalizations, are the most common movement disorders in children. Understanding and accurately diagnosing tic disorders are crucial for providing appropriate care and management.
JOURNAL OF CLINICAL MEDICINE
(2021)
Article
Behavioral Sciences
Lina Schubert, Julius Verrel, Amelie Behm, Tobias Baeumer, Christian Beste, Alexander Muenchau
Summary: The study found that associations between urges and tics in patients with Gilles de la Tourette syndrome are complex and heterogeneous, with some individuals not showing the expected positive correlation, and even displaying negative associations. While most patients demonstrated a positive relationship between urges and tics, there were substantial inter-individual differences in these associations.
Review
Psychology, Multidisciplinary
Songting Shou, Yuanliang Li, Guohui Fan, Qiang Zhang, Yurou Yan, Tiying Lv, Junhong Wang
Summary: The study suggests that cognitive-behavioral therapy (CBT) has a better intervention effect on tic disorder, significantly reducing total tic scores and motor tic scores, but not significantly reducing vocal tic scores. Future research should focus on developing new interventions to improve symptoms in different patients, especially for vocal tics.
FRONTIERS IN PSYCHOLOGY
(2022)
Article
Neurosciences
Xuanzi Zhou, Zhaoying Liao, Yi Li, Nanqing Wang, Nong Xiao
Summary: This retrospective study analyzed 126 children diagnosed with Tourette syndrome (TS) at Children's Hospital of Chongqing Medical University from 2019 to 2021. The treatment included tiapride (n = 60) and topiramate (n = 66). The results showed that both tiapride and topiramate significantly reduced tic severity scores, with topiramate showing better results. Furthermore, medication led to significant reduction in five subscores of CPRS in TS patients. However, there was no significant difference in CBCL scores after treatment in both tiapride and topiramate groups.
Article
Clinical Neurology
Melanie J. Firestone, Stacy Holzbauer, Christine Conelea, Richard Danila, Kirk Smith, Rebecca H. Bitsko, Susan M. Klammer, Stefan Gingerich, Ruth Lynfield
Summary: On October 15, 2021, the Minnesota Department of Health initiated an investigation into a cluster of students in a school displaying tic-like behaviors believed to be linked to recent COVID-19. Through interviews and questionnaires, it was discovered that eight female students aged 15-17 had tic-like behaviors lasting more than 24 hours. These behaviors were found to be associated with underlying mental health issues rather than the immediate effects of COVID-19. This study emphasizes the importance of understanding functional tic-like behaviors and adolescent mental health.
FRONTIERS IN NEUROLOGY
(2023)
Article
Oncology
Judith E. Carroll, Zev M. Nakamura, Brent J. Small, Xingtao Zhou, Harvey J. Cohen, Tim A. Ahles, Jaeil Ahn, Traci N. Bethea, Martine Extermann, Deena Graham, Claudine Isaacs, Heather S. L. Jim, Paul B. Jacobsen, Brenna C. McDonald, Sunita K. Patel, Kelly Rentscher, James Root, Andrew J. Saykin, Danielle B. Tometich, Kathleen Van Dyk, Wanting Zhai, Elizabeth C. Breen, Jeanne S. Mandelblatt
Summary: The study examined the longitudinal relationships between levels of C-reactive protein (CRP) and cognition in older breast cancer survivors and noncancer controls. The results showed that breast cancer survivors had higher levels of CRP, and increased CRP levels predicted lower cognitive function. This suggests that chronic inflammation may play a role in the development of cognitive problems.
JOURNAL OF CLINICAL ONCOLOGY
(2023)
Article
Audiology & Speech-Language Pathology
Peter Hutchison, Hannah Maeda, Craig Formby, Brent J. Small, David A. Eddins, Ann Clock Eddins
Summary: There is evidence that the auditory system adapts to hearing loss by modulating central auditory gain mechanisms. In this study, wearing a unilateral earplug for two weeks induced changes in the acoustic reflex threshold (ART), loudness perception, and cortical auditory steady-state response (ASSR). Results showed asymmetrical changes in cortical activity and an increase in central gain in the brainstem. These findings provide new insights into adaptive homeostatic plasticity and can be useful in future studies with clinical populations.
Article
Oncology
AnnaLynn M. Williams, Jeanne Mandelblatt, Mingjuan Wang, Gregory T. Armstrong, Nickhill Bhakta, Tara M. Brinkman, Wassim Chemaitilly, Matthew J. Ehrhardt, Daniel A. Mulrooney, Brent J. Small, Zhaoming Wang, Deokumar Srivastava, Leslie L. Robison, Melissa M. Hudson, Kirsten K. Ness, Kevin R. Krull
Summary: This study aimed to compare the accumulation of deficits in survivors of pediatric cancer with community controls and examine associations with host and treatment factors, neurocognition, and mortality. The results showed that pediatric cancer survivors experience clinically significant premature aging, with a DAI score of 0.16 at age 30 corresponding to age 63 in controls (33 years premature aging). Higher DAI scores were associated with increased risk of neurocognitive impairment and death.
JNCI-JOURNAL OF THE NATIONAL CANCER INSTITUTE
(2023)
Article
Psychology, Multidisciplinary
Danielle B. Tometich, Catherine E. Mosher, Melissa Cyders, Brenna C. McDonald, Andrew J. Saykin, Brent J. Small, Zhai Wanting, Zhou Xingtao, Heather S. L. Jim, Paul Jacobsen, Tim A. Ahles, James C. Root, Deena Graham, Sunita K. Patel, Jeanne Mandelblatt
Summary: Physical activity may improve cognitive function for older cancer survivors, and cognitive function may also affect the ability to organize oneself to be physically active. However, the expected prospective relationships between cognition and physical activity were not found in this study. The findings indicate that there is cross-sectional association between cognition and physical activity in survivors, but long-term predictive relationships were not observed. The study suggests that future research should consider the impact of cognitive function when older cancer survivors are attempting to increase their physical activity.
ANNALS OF BEHAVIORAL MEDICINE
(2023)
Article
Geriatrics & Gerontology
Hillary J. Rouse, Zahinoor Ismail, Ross Andel, Victor A. Molinari, John A. Schinka, Brent J. Small
Summary: This study examined the impact of mild behavioral impairment (MBI) on cognitive performance among cognitively healthy older adults and those with mild cognitive impairment (MCI). The results showed that individuals with MBI performed worse on tasks of attention, episodic memory, executive function, language, and processing speed, and exhibited greater decline over time. The presence of MBI was also associated with poorer performance on tasks of visuospatial ability, executive function, and processing speed among individuals with MCI.
JOURNALS OF GERONTOLOGY SERIES A-BIOLOGICAL SCIENCES AND MEDICAL SCIENCES
(2023)
Article
Oncology
Kelly Nudelman, Kwangsik Nho, Michael Zhang, Brenna C. McDonald, Wanting Zhai, Brent J. Small, Claire E. Wegel, Paul B. Jacobsen, Heather S. L. Jim, Sunita K. Patel, Deena M. A. Graham, Tim A. Ahles, James C. Root, Tatiana Foroud, Elizabeth C. Breen, Judith E. Carroll, Jeanne S. Mandelblatt, Andrew J. Saykin
Summary: This study found that genetics may play an important role in modifying risk for cognitive decline in older female breast cancer survivors. Several genetic variants and genes were identified to be associated with differences in patterns of cognitive decline in cancer patients compared to controls. Further research and validation of these findings in other cancer populations is necessary to inform therapeutic research and evaluations of risk for cognitive decline in older cancer survivors.
Article
Gastroenterology & Hepatology
Xiaoyin Li, Aasha I. Hoogland, Brent J. Small, Sylvia L. Crowder, Brian D. Gonzalez, Laura B. Oswald, Alix G. Sleight, Nathalie Nguyen, Nicole C. Lorona, Victoria Damerell, Khaled R. Komrokji, Kathi Mooney, Mary C. Playdon, Cornelia M. Ulrich, Christopher I. Li, David Shibata, Adetunji T. Toriola, Jennifer Ose, Anita R. Peoples, Erin M. Siegel, Julienne E. Bower, Martin Schneider, Biljana Gigic, Jane C. Figueiredo, Heather S. L. Jim
Summary: This study aimed to identify groups of colorectal cancer patients based on fatigue trajectories and examine the factors that differentiate these groups. Three distinct groups were identified, with a high-fatigue group experiencing significant improvement after 6 months. Patients diagnosed with Stage II-IV disease and/or current smokers were more likely to be in the high fatigue group. Early supportive care may be beneficial for patients with high fatigue at diagnosis.
COLORECTAL DISEASE
(2023)
Article
Psychiatry
Takahiro Soda, Amanda R. Merner, Brent J. Small, Laura N. Torgerson, Katrina Munoz, Jehannine Austin, Eric A. Storch, Stacey Pereira, Gabriel Lazarq-Munoz
Summary: The purpose of this study was to examine the practices and attitudes of child and adolescent psychiatrists (CAP) regarding diagnostic genetic and pharmacogenetic (PGx) testing. The survey of 958 US-based practicing CAP found that over half of the respondents had ordered or referred for a genetic test in the past year. Most agreed that it is their responsibility to discuss genetic information with their patients but rated their knowledge of genetic testing practice guidelines as poor. PGx testing was found to be the most commonly ordered test and was considered at least slightly useful in child and adolescent psychiatry by the majority of respondents. Patient requests and provider misinterpretation of PGx were identified as factors affecting the ordering practices and clinical management.
PSYCHIATRY RESEARCH
(2023)
Article
Oncology
Britney M. Veal, Stacey B. Scott, Heather S. L. Jim, Brent J. Small
Summary: Subjective reports of cancer-related cognitive impairment often exceed objective findings from in-person neuropsychological assessments. This study examined the association between subjective cognition and real-time objective cognitive performance, as well as fatigue and depressed mood, in breast cancer survivors. The results showed that subjective cognition was consistently related to self-reported fatigue and depressed mood, while specific memory lapses were associated with both in-person and daily objective cognitive performance. Incorporating reports of memory lapses may help identify individuals with objectively measured cancer-related cognitive impairment.
Article
Oncology
Aasha I. Hoogland, Brent J. Small, Laura B. Oswald, Crystal Bryant, Yvelise Rodriguez, Brian D. Gonzalez, Xiaoyin Li, Michelle C. Janelsins, Hailey W. Bulls, Brian W. James, Bianca Arboleda, Claudia Colon-Echevarria, Mary K. Townsend, Shelley S. Tworoger, Paulo C. Rodriguez, Julienne E. Bower, Sachin M. Apte, Robert M. Wenham, Heather S. L. Jim
Summary: Treatment-related symptoms such as fatigue, depression, and disruptions in sleep and physical activity are common in gynecologic cancer patients. Higher levels of inflammation, particularly C-reactive protein, are associated with worse symptomatology, specifically depression and disrupted physical activity. However, inflammation may not be significantly related to fatigue or sleep disturbance.
Letter
Hematology
Anna Barata, Aasha I. Hoogland, Brent J. Small, Frederick L. Locke, Heather S. L. Jim
TRANSPLANTATION AND CELLULAR THERAPY
(2023)
Article
Gerontology
Soomi Lee, Monica E. Nelson, Fumiko Hamada, Meredith L. Wallace, Ross Andel, Orfeu M. Buxton, David M. Almeida, Constantine Lyketsos, Brent J. Small
Summary: The relationship between sleep disorders and cognitive decline among older adults is complex, especially in individuals with impaired cognition. Findings suggest that certain sleep disorder diagnoses may be associated with better baseline cognitive performance and slower decline in cognitive abilities over time.
Article
Hematology
Anna Barata, Aasha Hoogland, Anuhya Kommalapati, Jennifer Logue, Taylor Welniak, Kelly A. Hyland, Sarah L. Eisel, Brent J. Small, Reena Jayani, Margaret Booth-Jones, Laura B. Oswald, Brian D. Gonzalez, Kedar S. Kirtane, Michael D. Jain, Sepideh Mokhtari, Julio C. Chavez, Aleksandr Lazaryan, Bijal D. Shah, Frederick L. Locke, Heather S. L. Jim
Summary: Chimeric antigen receptor (CAR) T-cell therapy can lead to cognitive deterioration in lymphoma patients, particularly within the first year of treatment. Specific risk factors such as immune effector cell-associated neurotoxicity syndrome (ICANS) and cytokine release syndrome (CRS), as well as non-specific risk factors like baseline quality of life and frailty, are associated with worsened cognition. However, other potential risk factors do not significantly contribute to cognitive changes. These findings can be informative for educating future patients about the potential cognitive effects of CAR T-cell therapy.
TRANSPLANTATION AND CELLULAR THERAPY
(2022)
Article
Gerontology
Soomi Lee, Taylor F. Vigoureux, Kathryn Hyer, Brent J. Small
Summary: This study examined sleep concerns among direct-care workers in long-term care and found that insomnia-related concerns were most prevalent. Most participants expressed interest in participating in a sleep intervention, with mindfulness strategies being the most preferred intervention. The study highlights the need to address the high prevalence of insomnia-related concerns among direct-care workers.
JOURNAL OF APPLIED GERONTOLOGY
(2022)
Article
Psychology, Developmental
Emily J. Ricketts, Sara Beth Wolicki, Melissa L. Danielson, Michelle Rozenman, Joseph F. McGuire, John Piacentini, Jonathan W. Mink, John T. Walkup, Douglas W. Woods, Rebecca H. Bitsko
Summary: The study found that children with both TS and ADHD were more likely to experience impairment in academic performance, writing, mathematics, and interpersonal relationships compared to those with only ADHD or TS. Targeted interventions specific to TS and ADHD may help alleviate these impairments.
CHILD PSYCHIATRY & HUMAN DEVELOPMENT
(2022)
Article
Psychiatry
Yafit Levin, Rahel Bachem, Dorit Brafman, Menachem Ben-Ezra
Summary: Negative symptoms of schizophrenia have been overlooked, and this study found an association between negative symptoms and the risk of dissociative disorder, independently of depression and anxiety symptoms. It is important to consider both negative symptoms and dissociative symptoms in clinical practice to better understand their interaction.
JOURNAL OF PSYCHIATRIC RESEARCH
(2024)
Review
Psychiatry
Roland Mergl, Sarah M. Quaatz, Vanessa Lemke, Antje-Kathrin Allgaier
Summary: Women who have had miscarriages or stillbirths have an increased risk for depressive symptoms and disorders, with a wide range of prevalence rates. However, depressive symptoms tend to diminish over time.
JOURNAL OF PSYCHIATRIC RESEARCH
(2024)
Article
Psychiatry
Hai-Yang Wang, Lin Zhang, Bei-Yan Guan, Shi-Yao Wang, Cui-Hong Zhang, Ming-Fei Ni, Yan-Wei Miao, Bing-Wei Zhang
Summary: This study investigates the association between cognitive reappraisal and panic disorder (PD), and finds that PD patients have weakened functional connectivity between the prefrontal cortex (PFC) and the amygdala, which is associated with the severity of PD symptoms. Additionally, cognitive reappraisal is negatively correlated with PD severity, and the PFC-amygdala functional connectivity plays a mediating role in this association.
JOURNAL OF PSYCHIATRIC RESEARCH
(2024)
Article
Psychiatry
Yanqiang Tao, Xinyuan Zou, Qihui Tang, Wenxin Hou, Shujian Wang, Zijuan Ma, Gang Liu, Xiangping Liu
Summary: Depression and anxiety are prevalent mental disorders among adolescents. The study utilized network analysis to examine the symptom dimension of depression and anxiety in different age groups of adolescents. The results indicated that different age groups have different key symptoms and bridging symptoms, highlighting the importance of targeting specific symptoms at different stages of adolescence in treatment to alleviate the comorbidity of anxiety and depression.
JOURNAL OF PSYCHIATRIC RESEARCH
(2024)
Article
Psychiatry
Philip J. Batterham, Aliza Werner-Seidler, Bridianne O'Dea, Alison L. Calear, Kate Maston, Andrew Mackinnon, Helen Christensen
Summary: Screening for psychological distress in adolescents is important, and the Distress Questionnaire-5 (DQ5) is a reliable measure for this purpose. The study found that DQ5 had good fit to a unidimensional construct, strong criterion and predictive validity, and sensitivity to change. The brevity and ease of interpretation of DQ5 make it suitable for screening in schools.
JOURNAL OF PSYCHIATRIC RESEARCH
(2024)
Article
Psychiatry
Xiaoli Liu, Qianqian Chen, Fang Cheng, Wenhao Zhuang, Wenwu Zhang, Yiping Tang, Dongsheng Zhou
Summary: This study found working memory defects in adolescents with major depressive disorder compared to healthy controls based on mean oxy-hemoglobin changes, which can be useful for distinguishing adolescents with MDD from healthy controls.
JOURNAL OF PSYCHIATRIC RESEARCH
(2024)
Article
Psychiatry
Anders Nordahl-Hansen, Hugo Cogo-Moreira, Sareh Panjeh, Daniel S. Quintana
Summary: This article aims to determine empirically-derived effect size thresholds associated with psychotherapy for depressive disorders by calculating the effect size distribution. The findings indicate that the observed effect size thresholds are larger than the suggested guidelines, which has implications for interpreting study effects and planning future research.
JOURNAL OF PSYCHIATRIC RESEARCH
(2024)
Article
Psychiatry
Guangli Zhao, Liyong Yu, Peixin Chen, Keli Zhu, Lu Yang, Wenting Lin, Yucai Luo, Zeyang Dou, Hao Xu, Pan Zhang, Tianmin Zhu, Siyi Yu
Summary: This study investigated the neural mechanisms underlying emotional attention bias in patients with CID using ERP and rs-FC approaches. The results revealed abnormalities in attention processing and connectivity in the emotion-cognition networks of CID patients. This study provides a neural basis for understanding attention bias in CID.
JOURNAL OF PSYCHIATRIC RESEARCH
(2024)
Article
Psychiatry
Seungyeon Lee, Sora Mun, Jiyeong Lee, Hee-Gyoo Kang
Summary: Major depressive disorder is a prevalent condition worldwide, but the proportion of patients receiving treatment has not increased. Biomarkers related to drug-treatment responses can be used to monitor the effectiveness of medication. Serum protein levels were compared among patients with depression who received medication, those who did not, and a control group. Eight biomarkers were identified, which can be used to monitor the effectiveness of drug treatment.
JOURNAL OF PSYCHIATRIC RESEARCH
(2024)
Article
Psychiatry
Alfredo L. Sklar, Fang -Cheng Yeh, Mark Curtis, Dylan Seebold, Brian A. Coffman, Dean F. Salisbury
Summary: This study investigated semantic verbal fluency (SVF) impairments in first-episode psychosis patients within the schizophrenia spectrum. The findings revealed disruptions in both functional and structural connectivity in these patients, as well as an association between enhanced connectivity in the right hemisphere and worse SVF performance and longer disease duration.
JOURNAL OF PSYCHIATRIC RESEARCH
(2024)
Article
Psychiatry
Maksymilian Rejek, Blazej Misiak
Summary: This study investigates the association of the exposome score (ES) with psychosis risk in a non-clinical population. The results show that the ES is associated with the extended psychosis phenotype, suggesting its potential to identify individuals who may benefit from further psychosis risk assessment.
JOURNAL OF PSYCHIATRIC RESEARCH
(2024)
