Article
Psychiatry
Sofia Laufer, Estee Herman, David Serfaty, Yael Latzer, Rachel Ashkenazi, Orna Attias, Sinai Oren, Meirav Shimomi, Moria Uziel, Adi Enoch-Levy, Eliezer Witztum, Daniel Stein
Summary: In Jewish Ultra-Orthodox males, some develop restricting-type AN with obsessional physical activity, while others develop unspecified restricting eating disorder in the context of OCD, leading to severe physical and emotional morbidity.
FRONTIERS IN PSYCHIATRY
(2023)
Article
Psychiatry
Geovanny Genaro Reivan Ortiz, Cristhian Javier Rivera Tapia, Braulio Andres Elizalde Martinez, Daniel Icaza
Summary: This study used a structural equation model to evaluate predictive variables of perfectionism in patients with Anorexia Nervosa, Bulimia Nervosa, and OCD, and found a significant correlation among these disorders.
FRONTIERS IN PSYCHIATRY
(2022)
Review
Neurosciences
Kai S. Thomas, Rosalind E. Birch, Catherine R. G. Jones, Ross E. Vanderwert
Summary: This review investigates executive functioning in anorexia nervosa (AN) and obsessive-compulsive disorder (OCD), revealing both similarities and differences in behavioral and neuroimaging findings. It provides important considerations for future research and contributes to the understanding of transdiagnostic correlates.
FRONTIERS IN HUMAN NEUROSCIENCE
(2022)
Article
Psychiatry
Johannes Baltasar Hessler-Kaufmann, Adrian Meule, Martin Greetfeld, Sandra Schlegl, Ulrich Voderholzer
Summary: Research on orthorexia nervosa (ON) has focused on non-clinical samples and found that it is more prevalent in eating disorder (ED) patients compared to the general population. The study suggests that ON may be a subtype of restrictive eating disorders and questions the exclusive health focus associated with the condition.
JOURNAL OF PSYCHOSOMATIC RESEARCH
(2021)
Article
Genetics & Heredity
Weichen Song, Weidi Wang, Shunying Yu, Guan Ning Lin
Summary: Anorexia nervosa and obsessive-compulsive disorder share a high co-morbidity rate and genetic basis, with risk genes showing distinct functional and spatiotemporal enrichment patterns. However, they also exhibit similar prefrontal cortex expression alterations, suggesting overlapping functional pathways as a disease mechanism which contribute to their similar but not identical clinical phenotypes.
Review
Medicine, General & Internal
Maria Pontillo, Valeria Zanna, Francesco Demaria, Roberto Averna, Cristina Di Vincenzo, Margherita De Biase, Michelangelo Di Luzio, Benedetta Foti, Maria Cristina Tata, Stefano Vicari
Summary: Research on Orthorexia nervosa (ON) is divided, with some studies suggesting it may fit the full-syndrome DSM-5 ED, while others propose that ON and DSM-5 EDs may co-occur. Only a few studies have suggested a relationship between ON and OCD. Currently, the clinical significance of ON and its relationship with EDs and OCD remains complicated and unclear, indicating a need for future research on the possible clinical course of ON.
JOURNAL OF CLINICAL MEDICINE
(2022)
Article
Psychiatry
Miaohan Deng, Yuan Wang, Shunying Yu, Qing Fan, Jianyin Qiu, Zhen Wang, Zeping Xiao
Summary: Our study identified neurodevelopment-related genes DMRT2 and miR-30a-5p to be associated with early-onset OCD, whereas we could not establish a direct association between serotonin genes and early-onset OCD. Additionally, variants such as HTR3D were found to be related to trait anxiety in OCD patients. Further studies based on biological or clinical characteristics may provide valuable insights for future research.
FRONTIERS IN PSYCHIATRY
(2022)
Article
Nutrition & Dietetics
Caterina Novara, Sara Piasentin, Sofia Mattioli, Susanna Pardini, Eleonora Maggio
Summary: The purpose of this study was to investigate the dimensions of perfectionism that represent orthorexia nervosa and to evaluate the impact of dieting on orthorexic features and perfectionistic behavior. The results showed that individuals with high orthorexic tendencies displayed higher levels of perfectionism, and orthorexia nervosa was significantly related to different facets of perfectionism. The study found that regardless of diet, perfectionism characterized orthorexia nervosa.
Article
Psychiatry
Yan-Rong Wang, Shao-hua Chang, Xiao-Min Ma, Ji-Ying Li, Rui-Xia Zhang, Jian-Qun Fang
Summary: The study found that male OCD patients have a thinner lower lip and female OCD patients have a smaller nasolabial angle. The facial features of adolescents with OCD were positively correlated with lower lip redness and neutralizing symptoms.
Editorial Material
Clinical Neurology
Trevor. W. Robbins
Summary: This scientific commentary discusses the research conducted by Kim et al. on the unbalanced fronto-pallidal neurocircuit underlying set shifting in patients with obsessive-compulsive disorder, published in the journal Brain.
Article
Nutrition & Dietetics
Montserrat Monserrat Hernandez, Angeles Arjona Garrido, Juan Carlos Checa Olmos, Dario Salguero Garcia
Summary: Current research indicates an increased risk of eating disorders in runners, with a significant relationship observed between negative running addiction (NRA) and compulsive eating, anorexia nervosa (AN), and/or bulimia nervosa (BN). Many runners are at risk of eating disorders, particularly long-distance runners. Childhood experiences, such as obesity or a healthy weight, play a key role in increasing the risk of eating disorders.
Review
Nutrition & Dietetics
Ana Claudia Rodrigues Candido, Sarah Dagostin Ferraz, Maria Laura Rodrigues Uggioni, Ivan Rosso Zanevan, Laura Colonetti, Antonio Jose Grande, Tamy Colonetti, Maria Ines da Rosa
Summary: This study aimed to assess the effects of omega-3 supplementation as an adjunct treatment for eating and psychological symptoms in patients with anorexia nervosa. The systematic review of the literature found no evidence of effectiveness of omega-3 supplementation in improving eating and psychological symptoms in patients with anorexia nervosa, regardless of dose, time or association with other components.
JOURNAL OF HUMAN NUTRITION AND DIETETICS
(2023)
Review
Neurosciences
Nishanth Sadashiva, Manjul Tripathi, Antonio De Salles
Summary: Psychiatric disorders are a hidden pandemic with limited treatment options. Neurosurgical interventions, including stereotactic radiosurgery (SRS), have shown successful treatment in specific psychiatric disorders, improving quality of life and offering a valid alternative for patients with no therapeutic options. SRS is cost-effective and reproducible among specialists, serving as an adjuvant to medical and behavioral treatments. This study reviews the contemporary role of SRS in various psychiatric disorders.
Article
Psychology, Clinical
Adrian Meule, Ulrich Voderholzer
Summary: This study found that obsessive-compulsive symptoms decrease during inpatient treatment of anorexia nervosa, without a symptom shift. However, patients with obsessive-compulsive tendencies should still receive targeted treatment for obsessive-compulsive symptoms during psychotherapeutic aftercare.
JOURNAL OF EATING DISORDERS
(2022)
Article
Medicine, General & Internal
Paolo Meneguzzo, Lorenza Di Pascoli, Maria Cristina Bindolo, Enrico Collantoni, Valentina Meregalli, Tatiana Zanetti, Angela Veronese, Elena Tenconi, Angela Favaro
Summary: In recent years, there have been notable changes in the definition, clinical characteristics, and psychological aspects of anorexia nervosa (AN), with the COVID-19 pandemic identified as a potential external factor impacting the clinical presentation of AN. This study aimed to evaluate the psychological and medical features of individuals with AN during the pandemic. The results revealed that patients during the pandemic were younger, experienced more severe psychological symptoms, and had higher hospitalization rates upon first access, suggesting distinct changes in symptomatology among patients.
JOURNAL OF CLINICAL MEDICINE
(2023)
Article
Clinical Neurology
E. Forcadell, B. Garcia-Delgar, R. Nicolau, A. Perez-Vigil, C. Cordovilla, L. Lazaro, L. Ibanez, P. Mir, M. Madruga-Garrido, M. Correa-Vela, A. Morer
Summary: Most people with persistent tics report experiencing a premonitory urge before the tic. The Premonitory Urge for Tics Scale (PUTS) is a widely used tool for assessing these sensations. In this study, the Spanish-language version of the PUTS was found to be valid and reliable in assessing premonitory urges in children and adolescents, particularly those over the age of 10.
Editorial Material
Psychology, Developmental
Luisa Lazaro
EUROPEAN CHILD & ADOLESCENT PSYCHIATRY
(2023)
Article
Psychology, Developmental
Matti Cervin, Blanca Garcia-Delgar, Rosa Calvo, Ana E. Ortiz, Luisa Lazaro
Summary: This study evaluates the performance of the OCI-CV questionnaire in identifying clinically significant symptoms of pediatric OCD. The results show that OCI-CV performs well in identifying contamination/cleaning symptoms, disturbing thoughts/checking symptoms, and symmetry/ordering symptoms, with high accuracy.
CHILD PSYCHIATRY & HUMAN DEVELOPMENT
(2023)
Article
Psychology, Developmental
Isabel Valli, Elena De la Serna, Alex G. Segura, Jose C. Pariente, Angels Calvet-Mirabent, Roger Borras, Daniel Ilzarbe, Dolores Moreno, Nuria Martin-Martinez, Inmaculada Baeza, Mireia Rosa-Justicia, Clemente Garcia-Rizo, Covadonga M. Diaz-Caneja, Nicolas A. Crossley, Allan H. Young, Eduard Vieta, Sergi Mas, Josefina Castro-Fornieles, Gisela Sugranyes
Summary: This study examined cognitive function and its clinical, genetic, and brain imaging correlates in youth at family risk for schizophrenia (SZ) and bipolar disorder (BP). Participants were grouped into intact, intermediate, and impaired clusters based on cognitive performance. The impaired cluster showed lower total brain surface area, particularly in the frontal and temporal cortices, and had poorer psychosocial functioning and worse PRS-COG compared to the other clusters and controls.
JOURNAL OF THE AMERICAN ACADEMY OF CHILD AND ADOLESCENT PSYCHIATRY
(2023)
Article
Psychology, Clinical
Alex G. Segura, Gisela Mezquida, Albert Martinez-Pinteno, Patricia Gasso, Natalia Rodriguez, Lucia Moreno-Izco, Silvia Amoretti, Miquel Bioque, Antonio Lobo, Ana Gonzalez-Pinto, Alicia Garcia-Alcon, Alexandra Roldan-Bejarano, Eduard Vieta, Elena de la Serna, Alba Toll, Manuel J. Cuesta, Sergi Mas, Miquel Bernardo
Summary: Early intervention is crucial for preventing the progression of psychotic disorders. This study found that genetic susceptibility related to cognitive performance is associated with an increased risk of first-episode psychosis (FEP) and its clinical and cognitive progression. Additionally, genetic susceptibility for depression is associated with a worsening trajectory of executive function and general cognitive status.
PSYCHOLOGICAL MEDICINE
(2023)
Article
Medicine, Research & Experimental
A. Martinez-Pinteno, N. Rodriguez, D. Olivares, S. Madero, M. Gomez, L. Prohens, C. Garcia-Rizo, S. Mas, C. Moren, E. Parellada, P. Gasso
Summary: Positive allosteric modulators of mGluR2, such as JNJ, may be beneficial in treating cognitive and negative symptoms of schizophrenia by mitigating the glutamate storm. In a mouse model of SZ, early treatment with JNJ or clozapine reversed behavioral and neuropathological deficits induced by ketamine exposure. JNJ treatment restored preference for a novel object and social novelty, as well as interest in a novel animal. Additionally, JNJ treatment normalized neuronal immunoreactivity in the prefrontal cortex and c-Fos expression in the hippocampus.
BIOMEDICINE & PHARMACOTHERAPY
(2023)
Article
Biochemistry & Molecular Biology
Patricia Gasso, Albert Martinez-Pinteno, Natalia Rodriguez, Santiago Madero, Marta Gomez, Alex G. G. Segura, Clemente Garca-Rizo, Constanza Moren, Sergi Mas, Eduard Parellada
Summary: Current APs effectively control positive psychotic symptoms by blocking dopamine D2 receptors, but have little effect on negative and cognitive symptoms. New pharmacological strategies, such as mGluR2 PAMs, are being developed to inhibit the release of glutamate and potentially improve symptoms. In this study, JNJ, an mGluR2 PAM, demonstrated neuroprotective and antiapoptotic activity in human neuroblastoma cells and showed potential as a novel therapeutic agent for schizophrenia.
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
(2023)
Article
Biochemistry & Molecular Biology
Nina Treder, Albert Martinez-Pinteno, Natalia Rodriguez, Nestor Arbelo, Santiago Madero, Marta Gomez, Clemente Garcia-Rizo, Sergi Mas, Patricia Gasso, Eduard Parellada, Constanza Moren
Summary: Schizophrenia is a heterogeneous mental disorder that affects approximately 1% of the global population. One of the main pathophysiological theories suggests an imbalance between excitatory glutamatergic pyramidal neurons and inhibitory GABAergic interneurons, involving N-methyl-D-aspartate receptors (NMDAr). This imbalance may lead to excessive glutamate storms, dendritic pruning, and cellular stress, including nitrosative stress mediated by nitric oxide (NO). The administration of NMDAr antagonists has been found to increase nitric oxide synthase (NOS) levels in specific brain regions, suggesting a potential target for early treatments. In a murine model, the protein levels of NOS were analyzed in the prefrontal cortex (PFC) and ventral hippocampus (HPC) after ketamine-induced schizophrenia, as well as after treatment with clozapine (CLZ) or JNJ-46356479 (JNJ). The findings suggest a dysregulation of the NOS system following NMDAr antagonist administration, which can be modulated by early CLZ and JNJ treatments.
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
(2023)
Article
Psychiatry
Gisela Mezquida, Silvia Amoretti, Miquel Bioque, Clemente Garcia-Rizo, Ana M. Sanchez-Torres, Laura Pina-Camacho, Purificacio Lopez-Pena, Anna Mane, Roberto Rodriguez-Jimenez, Iluminada Corripio, Salvador Sarro, Angela Ibanez, Judith Usall, Maria Paz Garcia Portilla, Eduard Vieta, Sergi Mas, Manuel J. Cuesta, Mara Parellada, Ana Gonzalez-Pinto, Esther Berrocoso, Miguel Bernardo
Summary: There are differences in risk factors and characteristics of developing predominant negative symptoms (PNS) in males and females with schizophrenia. The results suggest that sex is an important confounding factor in studies comparing schizophrenia patients with predominant and non-predominant negative symptomatology.
SPANISH JOURNAL OF PSYCHIATRY AND MENTAL HEALTH
(2023)
Article
Psychiatry
Isabel Valli, Alex Gonzalez Segura, Norma Verdolini, Clemente Garcia-Rizo, Daniel Berge, Inmaculada J. Baeza, Manuel Cuesta, Ana Gonzalez-Pinto, Antonio Lobo, Anabel Martinez-Aran, Gisela Mezquida, Laura Pina-Camacho, Alexandra Roldan Bejarano, Sergi Mas, Philip McGuire, Miquel Bernardo, Eduard Vieta
Summary: Obstetric complications (OCs) are important factors contributing to psychosis risk. This study found that complications of pregnancy and abnormalities of foetal growth are significantly associated with psychosis, while complications of delivery are not. There is no significant interaction between genetic risk and OCs. Different types of OCs may have different impacts on psychosis risk based on their nature and timeframe.
ACTA PSYCHIATRICA SCANDINAVICA
(2023)
Article
Psychiatry
Alyson Zwicker, Janice M. Fullerton, Niamh Mullins, Frances Rice, Danella M. Hafeman, Neeltje E. M. van Haren, Nikita Setiaman, John A. Merranko, Benjamin I. Goldstein, Alessandra G. Ferrera, Emma K. Stapp, Elena de la Serna, Dolores Moreno, Gisela Sugranyes, Sergio Mas Herrero, Gloria Roberts, Claudio Toma, Peter R. Schofield, Howard J. Edenberg, Holly C. Wilcox, Melvin G. McInnis, Victoria Powell, Lukas Propper, Eileen Denovan-Wright, Guy Rouleau, Josefina Castro-Fornieles, Manon H. J. Hillegers, Boris Birmaher, Anita Thapar, Philip B. Mitchell, Cathryn M. Lewis, Martin Alda, John I. Nurnberger, Rudolf Uher
Summary: The authors found that polygenic scores (PGSs) can complement family history to improve identification of risk for major mood and psychotic disorders. PGSs for neuroticism and subjective well-being are significantly associated with the onsets of disorders, and PGSs for psychiatric illness have limited predictive power when family history is known.
AMERICAN JOURNAL OF PSYCHIATRY
(2023)
Article
Psychiatry
Alex G. Segura, Elena de la Serna, Gisela Sugranyes, Inmaculada Baeza, Isabel Valli, Covadonga Diaz-Caneja, Nuria Martin, Dolores M. Moreno, Patricia Gasso, Natalia Rodriguez, Sergi Mas, Josefina Castro-Fornieles
Summary: Epigenetic modifications change during lifespan and can be influenced by external stimuli. Stressors can alter the epigenetic pattern and play a critical role in the onset of schizophrenia and bipolar disorder. This study examined the differences in age-related epigenetic modifications between young individuals at familial high risk (FHR) and controls, as well as their association with environmental stressors. The findings showed that FHR individuals had a slower pace of biological aging compared to controls, suggesting an asynchrony in epigenetic age. The impact of specific environmental stressors on methylation pattern changes remains unclear and further research is needed for personalized psychiatry tools.
TRANSLATIONAL PSYCHIATRY
(2023)
Article
Psychiatry
Patricia Camprodon-Boadas, Elena De La Serna, Maria Teresa Plana, Itziar Flamarique, Luisa Lazaro, Roger Borras, Inmaculada Baeza, Elisabet Tasa-Vinyals, Gisela Sugranyes, Ana Encarnacion Ortiz, Josefina Castro-Fornieles
Summary: This study analyzed the psychometric properties of the Brown Assessment of Beliefs Scale (BABS) in adolescents diagnosed with first-episode psychosis, obsessive-compulsive disorder, or anorexia nervosa. It found that the BABS scale is a valid and reliable tool for assessing delusionality in these adolescents, with significant differences observed among the disorders. Assessing these symptoms could have a positive impact on treatment management and prognosis.
PSYCHIATRY RESEARCH
(2023)
Article
Psychiatry
Alex G. Segura, Anna Mane, Llucia Prohens, Natalia Rodriguez, Gisela Mezquida, Manuel Cuesta, Eduard Vieta, Silvia Amoretti, Antonio Lobo, Ana Gonzalez-Pinto, Covadonga M. Diaz-Caneja, Alexandra Roldan Bejarano, Esther Jimenez, Immaculada Baeza, Teresa Legido, Jeronimo Saiz-Ruiz, Miguel Bernardo, Sergi Mas
Summary: The study aimed to investigate the association between cannabis-related polygenic risk scores (PRS) and cannabis use and clinical course after first-episode psychosis (FEP). The results showed that cannabis use was associated with increased positive symptoms and younger age of cannabis initiation influenced the progression of symptoms. Patients with higher cannabis PRS had increased baseline cannabis use and the PRS for lifetime cannabis initiation was associated with negative and general symptomatology over follow-up. These findings suggest that genetic factors may play a role in cannabis use and symptom progression after FEP.
PSYCHIATRY RESEARCH
(2023)
Article
Psychiatry
Yafit Levin, Rahel Bachem, Dorit Brafman, Menachem Ben-Ezra
Summary: Negative symptoms of schizophrenia have been overlooked, and this study found an association between negative symptoms and the risk of dissociative disorder, independently of depression and anxiety symptoms. It is important to consider both negative symptoms and dissociative symptoms in clinical practice to better understand their interaction.
JOURNAL OF PSYCHIATRIC RESEARCH
(2024)
Review
Psychiatry
Roland Mergl, Sarah M. Quaatz, Vanessa Lemke, Antje-Kathrin Allgaier
Summary: Women who have had miscarriages or stillbirths have an increased risk for depressive symptoms and disorders, with a wide range of prevalence rates. However, depressive symptoms tend to diminish over time.
JOURNAL OF PSYCHIATRIC RESEARCH
(2024)
Article
Psychiatry
Hai-Yang Wang, Lin Zhang, Bei-Yan Guan, Shi-Yao Wang, Cui-Hong Zhang, Ming-Fei Ni, Yan-Wei Miao, Bing-Wei Zhang
Summary: This study investigates the association between cognitive reappraisal and panic disorder (PD), and finds that PD patients have weakened functional connectivity between the prefrontal cortex (PFC) and the amygdala, which is associated with the severity of PD symptoms. Additionally, cognitive reappraisal is negatively correlated with PD severity, and the PFC-amygdala functional connectivity plays a mediating role in this association.
JOURNAL OF PSYCHIATRIC RESEARCH
(2024)
Article
Psychiatry
Yanqiang Tao, Xinyuan Zou, Qihui Tang, Wenxin Hou, Shujian Wang, Zijuan Ma, Gang Liu, Xiangping Liu
Summary: Depression and anxiety are prevalent mental disorders among adolescents. The study utilized network analysis to examine the symptom dimension of depression and anxiety in different age groups of adolescents. The results indicated that different age groups have different key symptoms and bridging symptoms, highlighting the importance of targeting specific symptoms at different stages of adolescence in treatment to alleviate the comorbidity of anxiety and depression.
JOURNAL OF PSYCHIATRIC RESEARCH
(2024)
Article
Psychiatry
Philip J. Batterham, Aliza Werner-Seidler, Bridianne O'Dea, Alison L. Calear, Kate Maston, Andrew Mackinnon, Helen Christensen
Summary: Screening for psychological distress in adolescents is important, and the Distress Questionnaire-5 (DQ5) is a reliable measure for this purpose. The study found that DQ5 had good fit to a unidimensional construct, strong criterion and predictive validity, and sensitivity to change. The brevity and ease of interpretation of DQ5 make it suitable for screening in schools.
JOURNAL OF PSYCHIATRIC RESEARCH
(2024)
Article
Psychiatry
Xiaoli Liu, Qianqian Chen, Fang Cheng, Wenhao Zhuang, Wenwu Zhang, Yiping Tang, Dongsheng Zhou
Summary: This study found working memory defects in adolescents with major depressive disorder compared to healthy controls based on mean oxy-hemoglobin changes, which can be useful for distinguishing adolescents with MDD from healthy controls.
JOURNAL OF PSYCHIATRIC RESEARCH
(2024)
Article
Psychiatry
Anders Nordahl-Hansen, Hugo Cogo-Moreira, Sareh Panjeh, Daniel S. Quintana
Summary: This article aims to determine empirically-derived effect size thresholds associated with psychotherapy for depressive disorders by calculating the effect size distribution. The findings indicate that the observed effect size thresholds are larger than the suggested guidelines, which has implications for interpreting study effects and planning future research.
JOURNAL OF PSYCHIATRIC RESEARCH
(2024)
Article
Psychiatry
Guangli Zhao, Liyong Yu, Peixin Chen, Keli Zhu, Lu Yang, Wenting Lin, Yucai Luo, Zeyang Dou, Hao Xu, Pan Zhang, Tianmin Zhu, Siyi Yu
Summary: This study investigated the neural mechanisms underlying emotional attention bias in patients with CID using ERP and rs-FC approaches. The results revealed abnormalities in attention processing and connectivity in the emotion-cognition networks of CID patients. This study provides a neural basis for understanding attention bias in CID.
JOURNAL OF PSYCHIATRIC RESEARCH
(2024)
Article
Psychiatry
Seungyeon Lee, Sora Mun, Jiyeong Lee, Hee-Gyoo Kang
Summary: Major depressive disorder is a prevalent condition worldwide, but the proportion of patients receiving treatment has not increased. Biomarkers related to drug-treatment responses can be used to monitor the effectiveness of medication. Serum protein levels were compared among patients with depression who received medication, those who did not, and a control group. Eight biomarkers were identified, which can be used to monitor the effectiveness of drug treatment.
JOURNAL OF PSYCHIATRIC RESEARCH
(2024)
Article
Psychiatry
Alfredo L. Sklar, Fang -Cheng Yeh, Mark Curtis, Dylan Seebold, Brian A. Coffman, Dean F. Salisbury
Summary: This study investigated semantic verbal fluency (SVF) impairments in first-episode psychosis patients within the schizophrenia spectrum. The findings revealed disruptions in both functional and structural connectivity in these patients, as well as an association between enhanced connectivity in the right hemisphere and worse SVF performance and longer disease duration.
JOURNAL OF PSYCHIATRIC RESEARCH
(2024)
Article
Psychiatry
Maksymilian Rejek, Blazej Misiak
Summary: This study investigates the association of the exposome score (ES) with psychosis risk in a non-clinical population. The results show that the ES is associated with the extended psychosis phenotype, suggesting its potential to identify individuals who may benefit from further psychosis risk assessment.
JOURNAL OF PSYCHIATRIC RESEARCH
(2024)
