Article
Chemistry, Medicinal
Cheng-Dien Hsu, Li-Hsuan Hsieh, Ya-Ling Chen, I-Cheng Lin, Ying-Ru Chen, Chih-Chi Chen, Hitoshi Shirakawa, Suh-Ching Yang
Summary: The study investigated the effects of polyphenolic compounds from pine bark extract (PE) on inattention and impulsivity in children with ADHD. PE supplementation significantly reduced ADHD symptoms and improved antioxidative status. This suggests that PE supplementation may have potential benefits in ameliorating symptoms and enhancing antioxidative status in children with ADHD.
PHYTOTHERAPY RESEARCH
(2021)
Article
Environmental Sciences
Chia-Huang Chang, Ching-Jung Yu, Jung-Chieh Du, Hsien-Chih Chiou, Jia-Woei Hou, Winnie Yang, Chian-Feng Chen, Hsin-Chang Chen, Ying-Sheue Chen, Betau Hwang, Mei-Lien Chen
Summary: This study reveals a potential link between organophosphate pesticide exposure and ADHD, related to oxidative stress and PON genetic polymorphisms. Children exposed to organophosphate pesticides may have higher levels of DMP and HNE-MA. The PON1 genetic polymorphism is associated with exposure levels and the risk of ADHD.
SCIENCE OF THE TOTAL ENVIRONMENT
(2021)
Article
Neurosciences
Markus Koelle, Sarah Mackert, Katharina Heckel, Alexandra Philipsen, Martin Ulrich, Georg Groen
Summary: This study found an association between RTV and white matter structural properties of the corticothalamic tract in adults with ADHD, which was not observed in healthy controls.
JOURNAL OF PSYCHIATRY & NEUROSCIENCE
(2022)
Article
Neurosciences
Aaron Barron, Cathal M. McCarthy, Gerard W. O'Keeffe
Summary: Preeclampsia is a common and serious hypertensive disorder of pregnancy, with in utero exposure potentially acting as an environmental risk factor for various neurodevelopmental disorders. The mechanisms are uncertain, but inflammation and oxidative stress likely play a major role in mediating this association.
MOLECULAR NEUROBIOLOGY
(2021)
Review
Chemistry, Medicinal
Toyosaku Ota, Kazuhiko Yamamuro, Kosuke Okazaki, Toshifumi Kishimoto
Summary: In summary, studies suggest that GXR is an effective monotherapy treatment option for adults with ADHD, with positive effects on attention, emotion, and behavior through its activity at post-synaptic alpha 2A receptors.
DRUG DESIGN DEVELOPMENT AND THERAPY
(2021)
Article
Psychology, Multidisciplinary
Morgan M. Grotewiel, Megan E. Crenshaw, Amelia Dorsey, Elizabeth Street
Summary: Hyperfocus and flow are intense concentration experiences associated with reduced perception of irrelevant stimuli and improved task performance. Hyperfocus has been historically seen as a symptom of ADHD, autism, or schizophrenia, while flow is regarded as an enjoyable experience in positive psychology. Recent studies suggest that hyperfocus and flow may be the same phenomenon viewed from different perspectives.
CURRENT PSYCHOLOGY
(2023)
Article
Immunology
Andrea Pozo-Rodrigalvarez, Roosa Ollaranta, Jenny Skoog, Milos Pekny, Marcela Pekna
Summary: The C3a receptor plays a crucial role in neurodevelopment and cognitive functions in the adult brain, with its deficiency associated with abnormalities in neurodevelopment, including short-term memory deficits and increased locomotor activity.
FRONTIERS IN IMMUNOLOGY
(2021)
Article
Medicine, General & Internal
Vincenza Spera, Alessandro Pallucchini, Marco Carli, Marco Maiello, Angelo G. Maremmani, Giulio Perugi, Icro Maremmani
Summary: The study compared demographic, clinical, and symptomatologic features between Dual Disorder A-ADHD (DD/A-ADHD) patients and those without dual disorders (NDD/A-ADHD). Results showed that NDD patients were more likely diagnosed with inattentive ADHD subtype, while DD/A-ADHD patients displayed more severe symptoms of hyperactivity/impulsivity. Type 1 and Type 2 substance use patterns had different effects on A-ADHD patients, leading to varied implications in diagnostic and therapeutic processes.
JOURNAL OF CLINICAL MEDICINE
(2021)
Article
Psychology, Multidisciplinary
Martina Vnukova, Radek Ptacek, Filip Dechterenko, Jiri Raboch, Martin Anders, Michal Goetz
Summary: The study aimed to assess the psychometric properties of the ASRS in the Czech Republic. The results showed that the Czech translation of the ASRS is appropriate and has acceptable psychometric properties. However, it is recommended to use this tool together with clinical judgment.
FRONTIERS IN PSYCHOLOGY
(2022)
Article
Multidisciplinary Sciences
Hsin-Yi Fan, Cheuk-Kwan Sun, Yu-Shian Cheng, Weilun Chung, Ruu-Fen Tzang, Hsien-Jane Chiu, Chun-Ning Ho, Kuo-Chuan Hung
Summary: This study provides a systematic review and analysis of the effectiveness of electroencephalogram-based neurofeedback (EEG-NF) in treating the core symptoms of attention-deficit hyperactivity disorder (ADHD) in adolescents/adults. The results suggest that EEG-NF can effectively improve inattention symptoms, but its effectiveness in reducing hyperactivity/impulsivity remains inconclusive.
SCIENTIFIC REPORTS
(2022)
Article
Pediatrics
Meritxell Rojo-Marticella, Victoria Arija, Paula Morales-Hidalgo, Patricia Esteban-Figuerola, Nuria Voltas-Moreso, Josefa Canals-Sans
Summary: This study aimed to describe the anthropometric status of school children with ADHD, comparing their age and clinical presentation with control children. The results showed that preschoolers with hyperactive-impulsive ADHD were taller, while elementary school children with combined ADHD were shorter and smaller. Medication may affect the height of children with inattentive presentation. Anthropometric and dietary monitoring should be recommended to parents of children with ADHD.
PEDIATRIC RESEARCH
(2023)
Article
Psychology, Multidisciplinary
Mana Oguchi, Toru Takahashi, Yusuke Nitta, Hiroaki Kumano
Summary: ADHD symptoms exacerbate the impact of procrastination and internalizing symptoms on emotional burden, but do not enhance the association between procrastination and internalizing symptoms. Procrastination should be the treatment target for individuals with ADHD and comorbid internalizing symptoms.
FRONTIERS IN PSYCHOLOGY
(2021)
Article
Psychiatry
Dara E. Babinski, Erika F. H. Saunders, Fan He, Duanping Liao, Amanda M. Pearl, Daniel A. Waschbusch
Summary: This study examined the diagnostic indicators, clinical characteristics, and functional impairment associated with adult ADHD using electronic medical records and self-report measures. The results showed a significant difference in prevalence of ADHD between self-report screening and medical records. ADHD was found to contribute to functional impairment even when controlling for other psychiatric comorbidities.
PSYCHIATRY RESEARCH
(2022)
Article
Biochemistry & Molecular Biology
Nathalie Brunkhorst-Kanaan, Sandra Trautmann, Yannick Schreiber, Dominique Thomas, Sarah Kittel-Schneider, Robert Gurke, Gerd Geisslinger, Andreas Reif, Irmgard Tegeder
Summary: This study found that patients with adult ADHD had increased plasma concentrations of sphingosine-1-phosphate (S1P d18:1), sphinganine-1-phosphate (S1P d18:0), anandamide (AEA), and arachidonoylglycerol, while patients with affective disorders had increased long chain ceramides, particularly Cer22:0, but lower levels of endocannabinoids. Patients with comorbid ADHD and affective disorders displayed intermediate levels of sphingolipids compared to non-comorbid patients. The ratio of S1P d18:1 to Cer22:0 may be a potential diagnostic or prognostic tool.
Review
Biochemistry & Molecular Biology
E. M. Bruxel, C. R. Moreira-Maia, G. C. Akutagava-Martins, T. P. Quinn, M. Klein, B. Franke, M. Ribases, P. Rovira, C. Sanchez-Mora, D. B. Kappel, N. R. Mota, E. H. Grevet, C. H. D. Bau, M. Arcos-Burgos, L. A. Rohde, M. H. Hutz
Summary: This study conducted a meta-analysis to investigate the association between ADGRL3 gene variants and ADHD susceptibility in children and adults, finding significant correlation in children but not in adults. The results suggest that ADGRL3 gene is predominantly associated with childhood ADHD.
MOLECULAR PSYCHIATRY
(2021)
Article
Dermatology
Ilknur Balta, Ayse S. Karadag, Salih Selek, Sevda Onder, Asiye Kanbay, Hatice Burakgazi-Yilmaz
INTERNATIONAL JOURNAL OF DERMATOLOGY
(2016)
Article
Clinical Neurology
Salih Selek, Abdurrahman Altindag, Gulben Saracoglu, Nurten Aksoy
JOURNAL OF AFFECTIVE DISORDERS
(2015)
Article
Psychiatry
I. Fatih Karababa, Huseyin Bayazit, Nihat Kilicaslan, Mustafa Celik, Hasan Cece, Ekrem Karakas, Salih Selek
PSYCHIATRY INVESTIGATION
(2015)
Article
Health Care Sciences & Services
Yaoyun Zhang, Olivia R. Zhang, Rui Li, Aaron Flores, Salih Selek, Xiang Y. Zhang, Hua Xu
HEALTH INFORMATICS JOURNAL
(2019)
Article
Health Care Sciences & Services
Fang Li, Guozheng Rao, Jingcheng Du, Yang Xiang, Yaoyun Zhang, Salih Selek, Jane Elizabeth Hamilton, Hua Xu, Cui Tao
HEALTH INFORMATICS JOURNAL
(2020)
Article
Clinical Neurology
Yezhe Lin, Joshua Tootoo, Melissa K. Allen, Omar F. Pinjari, Jair C. Soares, Salih Selek
JOURNAL OF AFFECTIVE DISORDERS
(2019)
Editorial Material
Psychiatry
Salih Selek, Joao Quevedo
BRAZILIAN JOURNAL OF PSYCHIATRY
(2019)
Article
Education & Educational Research
Smita Saraykar, Ayman Saleh, Salih Selek
ACADEMIC PSYCHIATRY
(2017)
Article
Substance Abuse
Serdar Suleyman Can, Salih Selek
JOURNAL OF SUBSTANCE USE
(2015)
Article
Clinical Neurology
Hasan Kandemir, Mehmet Emin Erdal, Salih Selek, Ozlem Izci Ay, Ibrahim Fatih Karababa, Mustafa Ertan Ay, Sultan Basmaci Kandemir, Senay Gorucu Yilmaz, Suat Ekinci, Bahar Tasdelen, Huseyin Bayazit
NEUROPSYCHIATRIC DISEASE AND TREATMENT
(2015)
Article
Clinical Neurology
Hasan Kandemir, Omer Aydemir, Suat Ekinci, Salih Selek, Sultan B. Kandemir, Huseyin Bayazit
NEUROPSYCHIATRIC DISEASE AND TREATMENT
(2015)
Article
Obstetrics & Gynecology
Mesut Yildiz, Mehmet Vural, Mehmet Emin Erdal, Ozlem Izci Ay, Senay Gorucu Yilmaz, Ibrahim Fatih Karababa, Salih Selek
INTERNATIONAL JOURNAL OF REPRODUCTIVE BIOMEDICINE
(2015)
Article
Medicine, General & Internal
Bulent Bahceci, Erman Bagcioglu, Mehmet Hanefi Kokacya, Aziz Ramazan Dilek, Ilkay Bahceci, Salih Selek
JOURNAL OF THE PAKISTAN MEDICAL ASSOCIATION
(2015)
Meeting Abstract
Neurosciences
Salih Selek, Huseyin Beyazit, Ibrahim F. Karababa, Hasan Cece
BIOLOGICAL PSYCHIATRY
(2014)
Article
Medicine, General & Internal
Ibrahim Fatih Karababa, Mehmet Asoglu, Salih Selek, Emine Poyraz, Sultan Basmaci Kandemir, Huseyin Bayazit, Ahmet Kucuk, Mahmut Kati, Saban Yalcin
ACTA MEDICA MEDITERRANEA
(2015)
Article
Psychiatry
Yafit Levin, Rahel Bachem, Dorit Brafman, Menachem Ben-Ezra
Summary: Negative symptoms of schizophrenia have been overlooked, and this study found an association between negative symptoms and the risk of dissociative disorder, independently of depression and anxiety symptoms. It is important to consider both negative symptoms and dissociative symptoms in clinical practice to better understand their interaction.
JOURNAL OF PSYCHIATRIC RESEARCH
(2024)
Review
Psychiatry
Roland Mergl, Sarah M. Quaatz, Vanessa Lemke, Antje-Kathrin Allgaier
Summary: Women who have had miscarriages or stillbirths have an increased risk for depressive symptoms and disorders, with a wide range of prevalence rates. However, depressive symptoms tend to diminish over time.
JOURNAL OF PSYCHIATRIC RESEARCH
(2024)
Article
Psychiatry
Hai-Yang Wang, Lin Zhang, Bei-Yan Guan, Shi-Yao Wang, Cui-Hong Zhang, Ming-Fei Ni, Yan-Wei Miao, Bing-Wei Zhang
Summary: This study investigates the association between cognitive reappraisal and panic disorder (PD), and finds that PD patients have weakened functional connectivity between the prefrontal cortex (PFC) and the amygdala, which is associated with the severity of PD symptoms. Additionally, cognitive reappraisal is negatively correlated with PD severity, and the PFC-amygdala functional connectivity plays a mediating role in this association.
JOURNAL OF PSYCHIATRIC RESEARCH
(2024)
Article
Psychiatry
Yanqiang Tao, Xinyuan Zou, Qihui Tang, Wenxin Hou, Shujian Wang, Zijuan Ma, Gang Liu, Xiangping Liu
Summary: Depression and anxiety are prevalent mental disorders among adolescents. The study utilized network analysis to examine the symptom dimension of depression and anxiety in different age groups of adolescents. The results indicated that different age groups have different key symptoms and bridging symptoms, highlighting the importance of targeting specific symptoms at different stages of adolescence in treatment to alleviate the comorbidity of anxiety and depression.
JOURNAL OF PSYCHIATRIC RESEARCH
(2024)
Article
Psychiatry
Philip J. Batterham, Aliza Werner-Seidler, Bridianne O'Dea, Alison L. Calear, Kate Maston, Andrew Mackinnon, Helen Christensen
Summary: Screening for psychological distress in adolescents is important, and the Distress Questionnaire-5 (DQ5) is a reliable measure for this purpose. The study found that DQ5 had good fit to a unidimensional construct, strong criterion and predictive validity, and sensitivity to change. The brevity and ease of interpretation of DQ5 make it suitable for screening in schools.
JOURNAL OF PSYCHIATRIC RESEARCH
(2024)
Article
Psychiatry
Xiaoli Liu, Qianqian Chen, Fang Cheng, Wenhao Zhuang, Wenwu Zhang, Yiping Tang, Dongsheng Zhou
Summary: This study found working memory defects in adolescents with major depressive disorder compared to healthy controls based on mean oxy-hemoglobin changes, which can be useful for distinguishing adolescents with MDD from healthy controls.
JOURNAL OF PSYCHIATRIC RESEARCH
(2024)
Article
Psychiatry
Anders Nordahl-Hansen, Hugo Cogo-Moreira, Sareh Panjeh, Daniel S. Quintana
Summary: This article aims to determine empirically-derived effect size thresholds associated with psychotherapy for depressive disorders by calculating the effect size distribution. The findings indicate that the observed effect size thresholds are larger than the suggested guidelines, which has implications for interpreting study effects and planning future research.
JOURNAL OF PSYCHIATRIC RESEARCH
(2024)
Article
Psychiatry
Guangli Zhao, Liyong Yu, Peixin Chen, Keli Zhu, Lu Yang, Wenting Lin, Yucai Luo, Zeyang Dou, Hao Xu, Pan Zhang, Tianmin Zhu, Siyi Yu
Summary: This study investigated the neural mechanisms underlying emotional attention bias in patients with CID using ERP and rs-FC approaches. The results revealed abnormalities in attention processing and connectivity in the emotion-cognition networks of CID patients. This study provides a neural basis for understanding attention bias in CID.
JOURNAL OF PSYCHIATRIC RESEARCH
(2024)
Article
Psychiatry
Seungyeon Lee, Sora Mun, Jiyeong Lee, Hee-Gyoo Kang
Summary: Major depressive disorder is a prevalent condition worldwide, but the proportion of patients receiving treatment has not increased. Biomarkers related to drug-treatment responses can be used to monitor the effectiveness of medication. Serum protein levels were compared among patients with depression who received medication, those who did not, and a control group. Eight biomarkers were identified, which can be used to monitor the effectiveness of drug treatment.
JOURNAL OF PSYCHIATRIC RESEARCH
(2024)
Article
Psychiatry
Alfredo L. Sklar, Fang -Cheng Yeh, Mark Curtis, Dylan Seebold, Brian A. Coffman, Dean F. Salisbury
Summary: This study investigated semantic verbal fluency (SVF) impairments in first-episode psychosis patients within the schizophrenia spectrum. The findings revealed disruptions in both functional and structural connectivity in these patients, as well as an association between enhanced connectivity in the right hemisphere and worse SVF performance and longer disease duration.
JOURNAL OF PSYCHIATRIC RESEARCH
(2024)
Article
Psychiatry
Maksymilian Rejek, Blazej Misiak
Summary: This study investigates the association of the exposome score (ES) with psychosis risk in a non-clinical population. The results show that the ES is associated with the extended psychosis phenotype, suggesting its potential to identify individuals who may benefit from further psychosis risk assessment.
JOURNAL OF PSYCHIATRIC RESEARCH
(2024)