Review
Psychiatry
Xue Xin Goh, Pek Yee Tang, Shiau Foon Tee
Summary: Medicated schizophrenia patients showed significantly higher levels of oxidative stress markers, while unmedicated patients had elevated plasma/serum malondialdehyde and nitric oxide. Drug-naive patients also exhibited higher lipid peroxidation, which may be associated with schizophrenia. Discontinuation of antipsychotic medication in the drug-free group led to increased plasma/serum nitric oxide levels, surpassing the effect seen in the atypical antipsychotic group.
ASIAN JOURNAL OF PSYCHIATRY
(2022)
Article
Nutrition & Dietetics
Annamaria D'Alessandro, Giovina Di Felice, Melania Manco, Anna Pastore, Simona Pezzi, Michela Mariani, Danilo Fintini, Andrea Onetti Muda, Ottavia Porzio
Summary: Obesity is a serious public health challenge that is closely linked to oxidative stress and metabolic disorders. This study analyzed serum samples from children with obesity and found abnormal levels of oxidative stress markers, which were positively correlated with obesity-related indices. Age was also found to be associated with oxidative stress.
Article
Pharmacology & Pharmacy
Caili Zhuo, Juanjuan Xin, Wenjing Huang, Die Zhang, Xin Yan, Ruli Li, He Li, Jie Lan, Lan Lin, Lingyu Li, Xuemei Wang, Linling Liu, Yingling Wang, Xinyue Li, Yan Mao, Hongying Chen, Sisi Wu, Xijing Yang, Wei Jiang
Summary: This study found that the exercise-mediated myokine Irisin plays an important role in cardiovascular diseases by regulating cell energy metabolism. Irisin protects against DOX-induced oxidative stress injury in cardiomyocytes by activating the AMPK-Nrf2 signaling axis, promoting mitochondrial fusion, improving mitochondrial dynamics and function, and strengthening the endogenous anti-oxidant system.
Article
Psychiatry
Jenny Borkent, Magdalini Ioannou, Tessa S. Folkertsma, Klaas J. Wardenaar, Bartholomeus C. M. Haarman, Harry van Goor, Iris E. C. Sommer, Arno R. Bourgonje
Summary: Recent research has shown that levels of serum free thiols (R-SH) are reduced in patients with recently diagnosed schizophrenia spectrum disorders (SSD) compared to healthy controls (HC), and are negatively correlated with the inflammatory marker CRP and age. Further studies are needed to investigate the role of R-SH in SSD.
PSYCHIATRY RESEARCH
(2023)
Article
Psychiatry
Gianluca Pandolfo, Giovanni Genovese, Antonio Bruno, Domenica Campolo, Valeria Tigano, Mariateresa Cristani, Marco Casciaro, Giovanni Pioggia, Sebastiano Gangemi
Summary: The pathophysiology of schizophrenia is still not well understood. Genetic factors and oxidative stress play key roles in its development and progression. Oxidative stress leads to the continuous production of oxidation products, such as AGEs and AOPPs, which interact with their receptors, amplifying the production of reactive oxygen species (ROS) and pro-inflammatory cytokines. In this study, plasma levels of AGEs and AOPPs were found to be significantly higher in schizophrenia patients compared to controls, confirming their involvement in mental disorders. Antioxidant nutraceuticals and a healthy lifestyle could reduce oxidative stress and alleviate schizophrenia symptoms.
PSYCHIATRY RESEARCH
(2022)
Review
Immunology
Arduino A. Mangoni, Angelo Zinellu
Summary: This study evaluated the pathophysiological role of neopterin in patients with rheumatic diseases through systematic review and meta-analysis. The results showed that neopterin concentrations were significantly higher in patients with RD compared to healthy controls. However, there were no significant associations found between neopterin concentrations and factors such as age and gender ratio, but associations were observed with geographical area and type of RD.
FRONTIERS IN IMMUNOLOGY
(2023)
Review
Biochemistry & Molecular Biology
Jennyffer Souza, Rodrigo Augusto da Silva, Debora da Luz Scheffer, Rafael Penteado, Alexandre Solano, Leonardo Barros, Henning Budde, Andres Trostchansky, Alexandra Latini
Summary: Regular physical exercise has been shown to enhance cellular antioxidant defenses by activating the NRF2 signaling pathway, which in turn has beneficial effects on the antioxidant systems in both the brain and skeletal muscle.
Article
Environmental Sciences
Ahmed Abdelraouf Salem, Kira Trares, Matthias Kohl, Eugene Jansen, Hermann Brenner, Ben Schottker
Summary: The study found a significant association between current smoking and increased levels of oxidative stress biomarker D-ROM, while there was no association with TTP levels. There is a dose-response relationship between smoking amount and D-ROM concentrations, indicating long-term effects of smoking on redox balance.
ENVIRONMENTAL RESEARCH
(2022)
Article
Biochemistry & Molecular Biology
Larissa E. van Eijk, Adriana Tami, Jan-Luuk Hillebrands, Wilfred F. A. den Dunnen, Martin H. de Borst, Peter H. J. van der Voort, Marian L. C. Bulthuis, Alida C. M. Veloo, Karin I. Wold, Maria F. Vincenti Gonzalez, Bernardina T. F. van der Gun, Harry van Goor, Arno R. Bourgonje
Summary: Patients with COVID-19 show increased systemic oxidative stress compared to healthy controls, as evidenced by significantly lower serum free thiol concentrations. These free thiols are positively associated with albumin and negatively associated with CRP, demonstrating discriminative ability in differentiating COVID-19 patients from healthy individuals.
Article
Veterinary Sciences
Luis G. Gonzalez Arostegui, Alberto Munoz Prieto, Luis Pardo Marin, Gregorio Garcia Lopez, Asta Tvarijonaviciute, Jose Joaquin Ceron Madrigal, Camila Peres Rubio
Summary: This study evaluates the changes in redox status in canine hypothyroidism and finds significant alterations in antioxidant and oxidant biomarkers in the serum and saliva of dogs with the disease. Further research is needed to validate these findings using larger populations.
BMC VETERINARY RESEARCH
(2023)
Review
Biochemistry & Molecular Biology
Natsuki Eguchi, Nosratola D. Vaziri, Donald C. Dafoe, Hirohito Ichii
Summary: Diabetes is a chronic metabolic disorder characterized by inappropriately elevated glucose levels due to impaired pancreatic beta cell function and insulin resistance. Studies have shown that endoplasmic reticulum stress, mitochondrial dysfunction, and oxidative stress play central roles in promoting beta cell dysfunction, with oxidative stress particularly important as beta cells exhibit lower antioxidative capacity. Efforts are being made to understand and counteract the effects of oxidative stress on beta cell health and survival.
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
(2021)
Review
Biochemistry & Molecular Biology
Nidhi Sharma, Subhrajit Biswas, Noura Al-Dayan, Alaa Saud Alhegaili, Maryam Sarwat
Summary: Reactive oxygen species (ROS) are harmful to cells, leading to oxidative stress and endoplasmic reticulum stress, which are key biological factors in the progression of hepatocellular carcinoma (HCC). The use of antioxidants from herbal sources can significantly reduce oxidative stress, and kaempferol may serve as a potential candidate in preventing HCC.
Review
Biochemistry & Molecular Biology
Tuany Eichwald, Lucila de Bortoli da Silva, Ananda Christina Staats Pires, Lais Niero, Erick Schnorrenberger, Clovis Colpani Filho, Gisele Espindola, Wei-Lin Huang, Gilles J. Guillemin, Jose E. Abdenur, Alexandra Latini
Summary: Tetrahydrobiopterin (BH4) is a cofactor that plays important roles in enzymatic conversions and metabolism. It has been found to have multiple biological functions beyond its traditional cofactor activity, including supporting essential pathways, enhancing antioxidant resistance, and protecting against inflammation. BH4 is regulated by three metabolic pathways and can be a potential pharmacological option for diseases related to mitochondrial dysfunction.
Article
Engineering, Chemical
I-Cheng Chen, Chen-Ying Su, Chi-Hau Fang, Hsu-Wei Fang
Summary: The study showed that preventative LED irradiation significantly reduced the formation of free radicals in OA-like cells, decreased the expression of inflammatory genes, and enhanced matrix gene expression. Combining preventative LED treatment with antioxidants demonstrated synergistic effects of anti-inflammation and MMP-13 reduction, presenting a novel therapeutic strategy for treating early OA.
JOURNAL OF THE TAIWAN INSTITUTE OF CHEMICAL ENGINEERS
(2021)
Article
Oncology
M. Leimkuhler, A. R. Bourgonje, H. van Goor, M. J. E. Campmans-Kuijpers, G. H. de Bock, B. L. van Leeuwen
Summary: This study found that patients with lower preoperative serum free thiol levels are more likely to develop postoperative complications and have a longer hospital stay.
ANNALS OF SURGICAL ONCOLOGY
(2022)
Article
Psychiatry
Cees J. Weeland, Selina Kasprzak, Niels T. de Joode, Yoshinari Abe, Pino Alonso, Stephanie H. Ameis, Alan Anticevic, Paul D. Arnold, Srinivas Balachander, Nerisa Banaj, Nuria Bargallo, Marcelo C. Batistuzzo, Francesco Benedetti, Jan C. Beucke, Irene Bollettini, Vilde Brecke, Silvia Brem, Carolina Cappi, Yuqi Cheng, Kang Ik K. Cho, Daniel L. C. Costa, Sara Dallaspezia, Damiaan Denys, Goi Khia Eng, Sonia Ferreira, Jamie D. Feusner, Martine Fontaine, Jean-Paul Fouche, Rachael G. Grazioplene, Patricia Gruner, Mengxin He, Yoshiyuki Hirano, Marcelo Q. Hoexter, Chaim Huyser, Hao Hu, Fern Jaspers-Fayer, Norbert Kathmann, Christian Kaufmann, Minah Kim, Kathrin Koch, Yoo Bin Kwak, Jun Soo Kwon, Luisa Lazaro, Chiang-Shan R. Li, Christine Lochner, Rachel Marsh, Ignacio Martinez-Zalacain, David Mataix-Cols, Jose M. Menchon, Luciano Minnuzi, Pedro Silva Moreira, Pedro Morgado, Akiko Nakagawa, Takashi Nakamae, Janardhanan C. Narayanaswamy, Erika L. Nurmi, Ana E. Ortiz, Jose C. Pariente, John Piacentini, Maria Pico-Perez, Fabrizio Piras, Federica Piras, Christopher Pittenger, Y. C. Janardhan Reddy, Daniela Rodriguez-Manrique, Yuki Sakai, Eiji Shimizu, Venkataram Shivakumar, Helen Blair Simpson, Noam Soreni, Carles Soriano-Mas, Nuno Sousa, Gianfranco Spalletta, Emily R. Stern, Michael C. Stevens, S. Evelyn Stewart, Philip R. Szeszko, Jumpei Takahashi, Tais Tanamatis, Jinsong Tang, Anders Lillevik Thorsen, David Tolin, Ysbrand D. van der Werf, Hein van Marle, Guido A. van Wingen, Daniela Vecchio, G. Venkatasubramanian, Susanne Walitza, Jicai Wang, Zhen Wang, Anri Watanabe, Lidewij H. Wolters, Xiufeng Xu, Je-Yeon Yun, Qing Zhao, Tonya White, Paul M. Thompson, Dan J. Stein, Odile A. van den Heuvel, Chris Vriend
Summary: Larger thalamic volume has been found in children with obsessive-compulsive disorder (OCD) and particular subregions may drive these differences. In adults, smaller volumes were observed across all subregions and the whole thalamic volume, mostly driven by medicated patients and associated with symptom severity.
TRANSLATIONAL PSYCHIATRY
(2022)
Editorial Material
Psychiatry
Nellai K. Chithra, Satish Suhas, Vanteemar S. Sreeraj, Ganesan Venkatasubramanian
ASIAN JOURNAL OF PSYCHIATRY
(2022)
Article
Psychiatry
Vittal Korann, Satish Suhas, Abhishek Appaji, Bhargavi Nagendra, Ananth Padmanabha, Arpitha Jacob, Priyanka Devi, Rose Dawn Bharath, Vijay Kumar, Shivarama Varambally, Ganesan Venkatasubramanian, Shyam Vasudeva Rao, Caroll A. B. Webers, Tos T. J. M. Berendschot, Naren P. Rao
Summary: This study examined the relationship between retinal vascular measures and brain white matter lesions in schizophrenia for the first time. The results showed that retinal vascular tortuosity and fractal dimension were associated with changes in cerebral white matter and may serve as proxy markers for cerebral microvasculature in schizophrenia. These findings could have important clinical implications for screening schizophrenia patients for risk of adverse cerebrovascular events.
ASIAN JOURNAL OF PSYCHIATRY
(2022)
Article
Neurosciences
Sunil Vasu Kalmady, Animesh Kumar Paul, Janardhanan C. Narayanaswamy, Rimjhim Agrawal, Venkataram Shivakumar, Andrew J. Greenshaw, Serdar M. Dursun, Russell Greiner, Ganesan Venkatasubramanian, Y. C. Janardhan Reddy
Summary: In this study, a transparent and explainable multiparcellation ensemble learning framework was applied to predict OCD, achieving better accuracy than neural networks. Transfer learning using features effective for schizophrenia also improved OCD prediction without loss in performance.
BIOLOGICAL PSYCHIATRY-COGNITIVE NEUROSCIENCE AND NEUROIMAGING
(2022)
Article
Genetics & Heredity
Manjula Subbanna, Venkataram Shivakumar, Gaurav Bhalerao, Shivarama Varambally, Ganesan Venkatasubramanian, Monojit Debnath
Summary: This study examines the impact of genetic variations and gene-gene interactions of Th17 pathway-related genes on the risk, psychopathology, and brain volume in schizophrenia patients. It found that these variations and interactions play a role in determining the risk for schizophrenia as well as influencing psychopathology and brain morphometric changes.
PSYCHIATRIC GENETICS
(2022)
Article
Psychiatry
Abhishek Appaji, Vaishak Harish, Vittal Korann, Priyanka Devi, Arpitha Jacob, Anantha Padmanabha, Vijay Kumar, Shivarama Varambally, Ganesan Venkatasubramanian, Shyam Vasudeva Rao, H. N. Suma, Caroll A. B. Webers, Tos T. J. M. Berendschot, Naren P. Rao
Summary: Psychiatric diagnosis still relies on subjective symptom reports, but recent studies have found retinal vascular abnormalities in patients with schizophrenia. This study used deep learning to analyze retinal fundus images and achieved high accuracy and AUC values for classifying schizophrenia patients, suggesting the potential utility of deep learning in assisting with diagnosis.
SCHIZOPHRENIA RESEARCH
(2022)
Letter
Psychiatry
Satish Suhas, Vanteemar S. Sreeraj, Chandrasegaran Amrutha, Geetha Desai, Ganesan Venkatasubramanian
SCHIZOPHRENIA RESEARCH
(2022)
Article
Medicine, General & Internal
Gomathi Venkatasubramanian, Devaki A. Kelkar, Susmita Mandal, Mohit Kumar Jolly, Madhura Kulkarni
Summary: Breast cancers are treated differently based on ER/PR or HER2 expression, while targeted therapy for triple-negative breast cancers remains challenging. YAP1 as a potential marker may help identify personalized treatment strategies for TNBC.
JOURNAL OF CLINICAL MEDICINE
(2022)
Letter
Psychology
Subhashini K. Rangarajan, Naga V. S. S. Gorthi, Sowmya Selvaraj, Preetie Shetty Akkunje, Rujuta Parlikar, Vanteemar S. Sreeraj, B. K. Yamini, G. V. Rashmi, Palanimuthu Thangaraju Sivakumar, N. Shivashankar, Ganesan Venkatasubramanian
INDIAN JOURNAL OF PSYCHOLOGICAL MEDICINE
(2023)
Article
Psychiatry
Petra J. W. Pouwels, Chris Vriend, Feng Liu, Niels T. de Joode, Maria C. G. Otaduy, Bruno Pastorello, Frances C. Robertson, Ganesan Venkatasubramanian, Jonathan Ipser, Seonjoo Lee, Marcelo C. Batistuzzo, Marcelo Q. Hoexter, Christine Lochner, Euripedes C. Miguel, Janardhanan C. Narayanaswamy, Rashmi Rao, Y. C. Janardhan Reddy, Roseli G. Shavitt, Karthik Sheshachala, Dan J. Stein, Anton J. L. M. van Balkom, Melanie Wall, Helen Blair Simpson, Odile A. van den Heuvel
Summary: This study aimed to translate neuroimaging findings in neuropsychiatric research to worldwide populations by using a harmonized MRI data acquisition and quality assessment method. The results showed that there was less variation within sites than between sites in terms of image quality measures (IQMs) and outcome measures. IQMs had less of an impact on outcome measures after preprocessing. Continuous monitoring of IQMs per site is valuable to detect potential artifacts and outliers.
INTERNATIONAL JOURNAL OF METHODS IN PSYCHIATRIC RESEARCH
(2023)
Editorial Material
Clinical Neurology
Radhika Suneel Kelkar, Vanteemar S. Sreeraj, Urvakhsh Meherwan Mehta, Ameya A. Patwardhan, Jagadisha Thirthalli, Daniel M. Blumberger
Review
Neurosciences
Harsh Pathak, Vanteemar S. Sreeraj, Ganesan Venkatasubramanian
Summary: Transcranial alternating current stimulation (tACS) may alleviate associated symptoms in schizophrenia by modulating neuronal oscillations through sinusoidal alternating current. Preliminary research has shown promising results in the utility of tACS for schizophrenia, particularly in the areas of cognitive deficits and positive symptoms. However, more rigorous randomized controlled trials are needed to substantiate these early findings.
CLINICAL PSYCHOPHARMACOLOGY AND NEUROSCIENCE
(2023)
Article
Neurosciences
Preethi V. Reddy, Pinku Mani Talukdar, Manjula Subbanna, Praerna H. Bhargav, Rashmi Arasappa, Ganesan Venkatasubramanian, Kesavan Muralidharan, Monojit Debnath
Summary: This study found that there were no differences in age and gender between patients with major depressive disorder (MDD) and healthy controls. The plasma levels of C1q, Factor B, and Factor H were significantly elevated in MDD patients compared to healthy controls. However, these complement proteins were not found to correlate with the clinical profile of MDD patients. These findings suggest that the alternative complement pathway plays an important role in immuno-inflammation in MDD.
CLINICAL PSYCHOPHARMACOLOGY AND NEUROSCIENCE
(2023)
Review
Neurosciences
Swarna Buddha Nayok, Vanteemar S. Sreeraj, Venkataram Shivakumar, Ganesan Venkatasubramanian
Summary: Interoception refers to the perception of signals from inside the body, playing a significant role in various bodily systems. It is closely related to the autonomic nervous system and has gained attention in neuropsychiatric research. Different facets of interoception and their assessments have been proposed, and its dysregulation is implicated in psychiatric disorders. This review aims to provide a comprehensive understanding of interoception, its disturbances, and its impact on psychiatric disorders.
CLINICAL PSYCHOPHARMACOLOGY AND NEUROSCIENCE
(2023)
Review
Psychiatry
Emily Chen Chen Smith, Emily Au, Sandra Pereira, Eesha Sharma, Ganesan Venkatasubramanian, Gary Remington, Sri Mahavir Agarwal, Margaret Hahn
Summary: Antipsychotics are crucial for treating schizophrenia spectrum disorders. Previous research suggests that these medications may lead to weight gain and dyslipidemia, while also improving psychiatric symptoms. This study explores the relationship between glucose parameters and changes in psychopathology, finding that increased glucose and insulin levels after treatment are associated with clinical improvement.
PSYCHIATRY RESEARCH
(2023)
Article
Psychiatry
Yafit Levin, Rahel Bachem, Dorit Brafman, Menachem Ben-Ezra
Summary: Negative symptoms of schizophrenia have been overlooked, and this study found an association between negative symptoms and the risk of dissociative disorder, independently of depression and anxiety symptoms. It is important to consider both negative symptoms and dissociative symptoms in clinical practice to better understand their interaction.
JOURNAL OF PSYCHIATRIC RESEARCH
(2024)
Review
Psychiatry
Roland Mergl, Sarah M. Quaatz, Vanessa Lemke, Antje-Kathrin Allgaier
Summary: Women who have had miscarriages or stillbirths have an increased risk for depressive symptoms and disorders, with a wide range of prevalence rates. However, depressive symptoms tend to diminish over time.
JOURNAL OF PSYCHIATRIC RESEARCH
(2024)
Article
Psychiatry
Hai-Yang Wang, Lin Zhang, Bei-Yan Guan, Shi-Yao Wang, Cui-Hong Zhang, Ming-Fei Ni, Yan-Wei Miao, Bing-Wei Zhang
Summary: This study investigates the association between cognitive reappraisal and panic disorder (PD), and finds that PD patients have weakened functional connectivity between the prefrontal cortex (PFC) and the amygdala, which is associated with the severity of PD symptoms. Additionally, cognitive reappraisal is negatively correlated with PD severity, and the PFC-amygdala functional connectivity plays a mediating role in this association.
JOURNAL OF PSYCHIATRIC RESEARCH
(2024)
Article
Psychiatry
Yanqiang Tao, Xinyuan Zou, Qihui Tang, Wenxin Hou, Shujian Wang, Zijuan Ma, Gang Liu, Xiangping Liu
Summary: Depression and anxiety are prevalent mental disorders among adolescents. The study utilized network analysis to examine the symptom dimension of depression and anxiety in different age groups of adolescents. The results indicated that different age groups have different key symptoms and bridging symptoms, highlighting the importance of targeting specific symptoms at different stages of adolescence in treatment to alleviate the comorbidity of anxiety and depression.
JOURNAL OF PSYCHIATRIC RESEARCH
(2024)
Article
Psychiatry
Philip J. Batterham, Aliza Werner-Seidler, Bridianne O'Dea, Alison L. Calear, Kate Maston, Andrew Mackinnon, Helen Christensen
Summary: Screening for psychological distress in adolescents is important, and the Distress Questionnaire-5 (DQ5) is a reliable measure for this purpose. The study found that DQ5 had good fit to a unidimensional construct, strong criterion and predictive validity, and sensitivity to change. The brevity and ease of interpretation of DQ5 make it suitable for screening in schools.
JOURNAL OF PSYCHIATRIC RESEARCH
(2024)
Article
Psychiatry
Xiaoli Liu, Qianqian Chen, Fang Cheng, Wenhao Zhuang, Wenwu Zhang, Yiping Tang, Dongsheng Zhou
Summary: This study found working memory defects in adolescents with major depressive disorder compared to healthy controls based on mean oxy-hemoglobin changes, which can be useful for distinguishing adolescents with MDD from healthy controls.
JOURNAL OF PSYCHIATRIC RESEARCH
(2024)
Article
Psychiatry
Anders Nordahl-Hansen, Hugo Cogo-Moreira, Sareh Panjeh, Daniel S. Quintana
Summary: This article aims to determine empirically-derived effect size thresholds associated with psychotherapy for depressive disorders by calculating the effect size distribution. The findings indicate that the observed effect size thresholds are larger than the suggested guidelines, which has implications for interpreting study effects and planning future research.
JOURNAL OF PSYCHIATRIC RESEARCH
(2024)
Article
Psychiatry
Guangli Zhao, Liyong Yu, Peixin Chen, Keli Zhu, Lu Yang, Wenting Lin, Yucai Luo, Zeyang Dou, Hao Xu, Pan Zhang, Tianmin Zhu, Siyi Yu
Summary: This study investigated the neural mechanisms underlying emotional attention bias in patients with CID using ERP and rs-FC approaches. The results revealed abnormalities in attention processing and connectivity in the emotion-cognition networks of CID patients. This study provides a neural basis for understanding attention bias in CID.
JOURNAL OF PSYCHIATRIC RESEARCH
(2024)
Article
Psychiatry
Seungyeon Lee, Sora Mun, Jiyeong Lee, Hee-Gyoo Kang
Summary: Major depressive disorder is a prevalent condition worldwide, but the proportion of patients receiving treatment has not increased. Biomarkers related to drug-treatment responses can be used to monitor the effectiveness of medication. Serum protein levels were compared among patients with depression who received medication, those who did not, and a control group. Eight biomarkers were identified, which can be used to monitor the effectiveness of drug treatment.
JOURNAL OF PSYCHIATRIC RESEARCH
(2024)
Article
Psychiatry
Alfredo L. Sklar, Fang -Cheng Yeh, Mark Curtis, Dylan Seebold, Brian A. Coffman, Dean F. Salisbury
Summary: This study investigated semantic verbal fluency (SVF) impairments in first-episode psychosis patients within the schizophrenia spectrum. The findings revealed disruptions in both functional and structural connectivity in these patients, as well as an association between enhanced connectivity in the right hemisphere and worse SVF performance and longer disease duration.
JOURNAL OF PSYCHIATRIC RESEARCH
(2024)
Article
Psychiatry
Maksymilian Rejek, Blazej Misiak
Summary: This study investigates the association of the exposome score (ES) with psychosis risk in a non-clinical population. The results show that the ES is associated with the extended psychosis phenotype, suggesting its potential to identify individuals who may benefit from further psychosis risk assessment.
JOURNAL OF PSYCHIATRIC RESEARCH
(2024)
