Melatonin attenuates hypoxic pulmonary hypertension by inhibiting the inflammation and the proliferation of pulmonary arterial smooth muscle cells

Extrapineal melatonin: sources, regulation, and potential functions

(2014) Darío Acuña-Castroviejo et al.   CELLULAR AND MOLECULAR LIFE SCIENCES

Inhibition of Nuclear Factor-κB in the Lungs Prevents Monocrotaline-Induced Pulmonary Hypertension in Mice

(2014) Li Li et al.   HYPERTENSION

Melatonin: a well-documented antioxidant with conditional pro-oxidant actions

(2014) Hong-Mei Zhang et al.   JOURNAL OF PINEAL RESEARCH

Melatonin Enhances the Anti-Tumor Effect of Fisetin by Inhibiting COX-2/iNOS and NF-κB/p300 Signaling Pathways

(2014) Canhui Yi et al.   PLoS One

Regulation of Hypoxia-induced Pulmonary Hypertension by Vascular Smooth Muscle Hypoxia-Inducible Factor-1α

(2013) Molly K. Ball et al.   AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE

15-Lipoxygenase Promotes Chronic Hypoxia–Induced Pulmonary Artery Inflammation via Positive Interaction With Nuclear Factor-κB

(2013) Jing Li et al.   ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY

Melatonin and its atheroprotective effects: A review

(2013) Gaia Favero et al.   MOLECULAR AND CELLULAR ENDOCRINOLOGY

Berberine Targets AP-2/hTERT, NF-κB/COX-2, HIF-1α/VEGF and Cytochrome-c/Caspase Signaling to Suppress Human Cancer Cell Growth

(2013) Lingyi Fu et al.   PLoS One

New mechanisms of pulmonary arterial hypertension: role of Ca2+ signaling

(2012) Frank K. Kuhr et al.   AMERICAN JOURNAL OF PHYSIOLOGY-HEART AND CIRCULATORY PHYSIOLOGY

17β-Estradiol Attenuates Hypoxic Pulmonary Hypertension via Estrogen Receptor–mediated Effects

(2012) Tim Lahm et al.   AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE

Melatonin suppresses proinflammatory mediators in lipopolysaccharide-stimulated CRL1999 cells via targeting MAPK, NF-κB, c/EBPβ, and p300 signaling

(2012) Dingbo Shi et al.   JOURNAL OF PINEAL RESEARCH

Melatonin suppresses tumor progression by reducing angiogenesis stimulated by HIF-1 in a mouse tumor model

(2012) Kil-Jung Kim et al.   JOURNAL OF PINEAL RESEARCH

On the free radical scavenging activities of melatonin's metabolites, AFMK and AMK

(2012) Annia Galano et al.   JOURNAL OF PINEAL RESEARCH

ERK1/2 MAP kinases: Structure, function, and regulation

(2012) Robert Roskoski   PHARMACOLOGICAL RESEARCH

World Health Organization Group III pulmonary hypertension

(2012) Hooman D. Poor et al.   PROGRESS IN CARDIOVASCULAR DISEASES

Reciprocal regulation of HIF-1α and 15-LO/15-HETE promotes anti-apoptosis process in pulmonary artery smooth muscle cells during hypoxia

(2012) Lan Yao et al.   PROSTAGLANDINS & OTHER LIPID MEDIATORS

HIF and the Lung

(2011) Larissa A. Shimoda et al.   AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE

Attenuation of leukocyte recruitment via CXCR1/2 inhibition stops the progression of PAH in mice with genetic ablation of endothelial BMPR-II

(2011) V. J. Burton et al.   BLOOD

Retracted: Mice lacking the Raf-1 kinase inhibitor protein exhibit exaggerated hypoxia-induced pulmonary hypertension

(2011) I Morecroft et al.   BRITISH JOURNAL OF PHARMACOLOGY

mTOR is required for pulmonary arterial vascular smooth muscle cell proliferation under chronic hypoxia

(2011) Vera P. Krymskaya et al.   FASEB JOURNAL

PI3K/Akt and MAPK/ERK1/2 signaling pathways are involved in IGF-1-induced VEGF-C upregulation in breast cancer

(2011) Chenfang Zhu et al.   JOURNAL OF CANCER RESEARCH AND CLINICAL ONCOLOGY

Extrapineal melatonin: analysis of its subcellular distribution and daily fluctuations

(2011) Carmen Venegas et al.   JOURNAL OF PINEAL RESEARCH

Beneficial effects of melatonin in cardiovascular disease

(2010) Russel J. Reiter et al.   ANNALS OF MEDICINE

Inflammation and Pulmonary Hypertension

(2010) Rajamma Mathew   Cardiology in Review

Cardiac hypertrophy and remodelling: pathophysiological consequences and protective effects of melatonin

(2010) Russel J Reiter et al.   JOURNAL OF HYPERTENSION

Absence of the Adenosine A2A Receptor Confers Pulmonary Arterial Hypertension and Increased Pulmonary Vascular Remodeling in Mice

(2010) M.H. Xu et al.   JOURNAL OF VASCULAR RESEARCH

Mechanisms of hypoxic pulmonary vasoconstriction and their roles in pulmonary hypertension: new findings for an old problem

(2009) Jeremy PT Ward et al.   CURRENT OPINION IN PHARMACOLOGY

Guidelines for the diagnosis and treatment of pulmonary hypertension: The Task Force for the Diagnosis and Treatment of Pulmonary Hypertension of the European Society of Cardiology (ESC) and the European Respiratory Society (ERS), endorsed by the International Society of Heart and Lung Transplantation (ISHLT)

(2009) et al.   EUROPEAN HEART JOURNAL

Nanoparticle-Mediated Delivery of Nuclear Factor κB Decoy Into Lungs Ameliorates Monocrotaline-Induced Pulmonary Arterial Hypertension

(2009) Satoshi Kimura et al.   HYPERTENSION

Diagnosis, Assessment, and Treatment of Non-Pulmonary Arterial Hypertension Pulmonary Hypertension

(2009) Marius M. Hoeper et al.   JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY

Cellular and Molecular Basis of Pulmonary Arterial Hypertension

(2009) Nicholas W. Morrell et al.   JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY

Inflammation, Growth Factors, and Pulmonary Vascular Remodeling

(2009) Paul M. Hassoun et al.   JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY

Induction of Vascular Remodeling in the Lung by Chronic House Dust Mite Exposure

(2008) Kristina Rydell-Törmänen et al.   AMERICAN JOURNAL OF RESPIRATORY CELL AND MOLECULAR BIOLOGY

Physiological effects of melatonin: Role of melatonin receptors and signal transduction pathways

(2008) S PANDIPERUMAL et al.   PROGRESS IN NEUROBIOLOGY

Melatonin modulates the expression of VEGF and HIF-1α induced by CoCl2in cultured cancer cells

(2007) Min Dai et al.   JOURNAL OF PINEAL RESEARCH