Review
Biochemistry & Molecular Biology
Joshua M. Bock, Ian M. Greenlund, Virend K. Somers, Sarah E. Baker
Summary: Patients with obstructive sleep apnea (OSA) have a higher risk of developing cardiovascular diseases, especially hypertension. However, potential sex differences in the sympathetic regulation of blood pressure in this population have not been investigated. This review aims to discuss the literature linking sympathetic nerve activity to hypertension in OSA, highlight recent experimental data supporting the hypothesis of sex differences in the regulation of sympathetic nerve activity in OSA, and explore potential sex differences in peripheral adrenergic signaling that may contribute to or offset cardiovascular risk in OSA patients.
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
(2023)
Article
Nutrition & Dietetics
Ciara Cooney, Ed Daly, Maria McDonagh, Lisa Ryan
Summary: This study compared weight changes in two groups of aging Irish adults with overweight and chronic diseases based on measured RMR and estimated RMR. Short-term weight reduction favored a decrease in cardiovascular disease risk factors in both groups, showing similar effects in improving weight outcomes.
Review
Neurosciences
Tomomi Karigo
Summary: This review provides an overview of the current understanding of mouse vocal communications, its underlying neural circuitry, and the potential to use vocal communications as a readout for the animal's internal states during social interactions.
NEUROSCIENCE RESEARCH
(2022)
Article
Nanoscience & Nanotechnology
Wantida Chaiyana, Sudarat Jiamphun, Suchanan Bezuidenhout, Kankanit Yeerong, Nutnicha Krueathanasing, Pattiya Thammasorn, Pipat Jittasai, Suphachai Tanakitvanicharoen, Singkome Tima, Songyot Anuchapreeda
Summary: This study aimed to extract oil from Gryllus bimaculatus de Geer, evaluate its potential for cosmeceutical applications, and develop nanoemulsions to enhance its cosmeceutical properties. The results showed that G. bimaculatus oil had antioxidant, anti-tyrosinase, and anti-skin aging activities. The oil was safe and could be successfully developed into nanoemulsions, which significantly enhanced its cosmeceutical effects.
INTERNATIONAL JOURNAL OF NANOMEDICINE
(2023)
Review
Medicine, General & Internal
Nahid Tabibzadeh, Gilles Crambert
Summary: The kidneys play a crucial role in maintaining the constant volume, pH, and electrolyte composition of the internal milieu by balancing outputs and inputs. Dysfunctions in the kidney, either due to internal alterations or external factors, can lead to various pathologies and affect other organ functions. Studying the alterations in the functions of the collecting duct has provided better understanding and management of related diseases, and the development of therapeutic tools.
JOURNAL OF INTERNAL MEDICINE
(2023)
Article
Cardiac & Cardiovascular Systems
Birgit Assmus, Christiane E. Angermann, Basil Alkhlout, Folkert W. Asselbergs, Steffen Schnupp, Jasper J. Brugts, Peter Nordbeck, Qian Zhou, Marie-Elena Brett, Greg Ginn, Philip B. Adamson, Michael Bohm, Stephan Rosenkranz
Summary: This study investigated the safety and effectiveness of PAP-guided remote patient management in heart failure patients. The results showed that the patients benefited during the post-implant follow-up, regardless of the presence or subtype of pulmonary hypertension at baseline.
EUROPEAN JOURNAL OF HEART FAILURE
(2022)
Article
Neurosciences
Maria Azanova, Maria Herrojo Ruiz, Alexis V. Belianin, Vasily Klucharev, Vadim V. Nikulin
Summary: This study investigated the greater risk aversion in females compared to males and found a link between rest-state theta oscillations and risk taking ability. The results suggest that reward sensitivity mediated by theta oscillations in the anterior cingulate cortex may contribute to the sex differences in risk-taking behavior.
FRONTIERS IN NEUROSCIENCE
(2021)
Article
Green & Sustainable Science & Technology
Weidong Zhu, Fei Yang, Zhenge Qiu, Naiying He, Xiaolong Zhu, Yaqin Li, Yuelin Xu, Zhigang Lu
Summary: This study evaluated the accuracy of GEDI L2A version 2 data in estimating ground elevation and canopy height by comparing it with airborne laser scanning (ALS) data. Among the six algorithms provided by the GEDI L2A data, algorithm a2 demonstrated higher accuracy than the others in detecting ground elevation and canopy height. To enhance the accuracy of canopy height estimation, this study proposed three backpropagation (BP) neural network inversion models based on GEDI, Landsat 8 OLI, and Landsat 9 OLI-2 data.
Article
Physiology
John D. Akins, Yoshiyuki Okada, Joseph M. Hendrix, Wanpen Vongpatanasin, Qi Fu
Summary: Previous studies have shown that older women have increased muscle sympathetic nerve activity (MSNA) responses during the cold pressor test (CPT). However, the impact of baseline MSNA on CPT reactivity in older adults remains unknown due to interindividual variability.
AMERICAN JOURNAL OF PHYSIOLOGY-REGULATORY INTEGRATIVE AND COMPARATIVE PHYSIOLOGY
(2023)
Review
Neurosciences
Ratan Das, Sudip Paul, Gajendra Kumar Mourya, Neelesh Kumar, Masaraf Hussain
Summary: This article provides an overview of various factors associated with the management of neurodegenerative disorders, focusing on assessment, rehabilitation, and assistance for gait and balance disorders.
FRONTIERS IN NEUROSCIENCE
(2022)
Article
Multidisciplinary Sciences
Sameed Ahmed, Jennifer C. Sullivan, Anita T. Layton
Summary: A personalized model for hypertension treatment based on sex and pathophysiological features was developed, revealing the significant roles these factors play in the response to hypertensive treatments.
Article
Chemistry, Physical
Larissa Braun, Max Hohenschutz, Olivier Diat, Regine von Klitzing, Pierre Bauduin
Summary: In recent research, it was found that the superchaotropic Keggin polyoxometalate alpha-SiW12O404 (SiW) can stabilize non-ionic surfactant foams through electrostatic repulsion. The precise mechanism of foam stabilization by SiW remained unresolved. Imaging and conductimetry were used to monitor the foam collapse, while small angle neutron scattering (SANS) tracked the evolution of film thickness. Thin film pressure balance (TFPB) measurements quantified the resistance of single foam films to external pressure and identified intra-film forces. The findings showed that SiW induces electrostatic repulsion within foam films at low SiW/surfactant ratios, and above a concentration threshold, excess SiW screens the electrostatic repulsion, resulting in thinner foam films. Despite this, the foam and single foam films remained stable due to an additional steric stabilizing force from trapped micelles inside the foam films, which acted as a surfactant reservoir and promoted self-healing of the interface, leading to more resilient foam films compared to bare surfactant foams/films.
JOURNAL OF COLLOID AND INTERFACE SCIENCE
(2023)
Article
Medicine, Research & Experimental
Ana Paula Oliverio Leite, Xiao C. Li, Ruman Hassan, Xiaowen Zheng, Barbara T. Alexander, Dulce Elena Casarini, Jia L. Zhuo
Summary: The present study demonstrates that deletion of AT1a receptors in the proximal tubules of the kidney attenuates Ang II-induced hypertension and kidney injury without significant differences between the sexes.
Article
Multidisciplinary Sciences
Chia-Hsin Yeh, Terry B. J. Kuo, Jia-Yi Li, Kuan-Liang Kuo, Chang-Ming Chern, Cheryl C. H. Yang, Hsin-Yi Huang
Summary: Cardiovascular function is influenced by age, sex, and state of consciousness. This study found that cardiovagal baroreflex sensitivity (BRS) exhibits different patterns in males and females before and after the age of 50, and these patterns are associated with changes during the sleep-wake cycle. Age and sex are important factors in determining BRS, with women showing a stronger association and an earlier decline in BRS compared to men. The findings highlight the clinical importance of understanding BRS patterns in different populations.
SCIENTIFIC REPORTS
(2022)
Article
Sociology
Shruti Chaudhry
Summary: This article explores how cross-sex friendships among older adults of South Asian heritage in Scotland reflect the norms of gender, sexualities, and intimate relationships in minority ethnic contexts. It argues that South Asian cultural norms pose challenges to the formation and maintenance of cross-sex friendships, which need to be managed in relation to familial ties and community expectations. The risks are particularly high for women, who face policing of their sexuality even as they age. These friendships signify social change and agency within diasporic communities, while also highlighting the ongoing importance of kin and community.
SOCIOLOGICAL RESEARCH ONLINE
(2022)
Article
Peripheral Vascular Disease
Benjamin Chant, Majda Bakali, Thomas Hinton, Amy E. Burchell, Angus K. Nightingale, Julian F. R. Paton, Emma C. Hart
Article
Peripheral Vascular Disease
Jonathan C. L. Rodrigues, Antonio Matteo Amadu, Amardeep Ghosh Dastidar, Iwan Harries, Amy E. Burchell, Laura E. K. Ratcliffe, Emma C. Hart, Mark C. K. Hamilton, Julian F. R. Paton, Angus K. Nightingale, Nathan E. Manghat
JOURNAL OF CLINICAL HYPERTENSION
(2018)
Article
Radiology, Nuclear Medicine & Medical Imaging
Jonathan C. L. Rodrigues, Tamas Erdei, Amardeep Ghosh Dastidar, Gergley Szantho, Amy E. Burchell, Laura E. K. Ratcliffe, Emma C. Hart, Angus K. Nightingale, Julian F. R. Paton, Nathan E. Manghat, Mark C. K. Hamilton
EUROPEAN RADIOLOGY
(2019)
Article
Biophysics
S. Neumann, F. Sophocleous, M. D. Kobetic, E. C. Hart, A. K. Nightingale, K. H. Parker, M. K. Hamilton, G. Biglino
PHYSIOLOGICAL MEASUREMENT
(2018)
Article
Peripheral Vascular Disease
Sandra Neumann, Amy E. Burchell, Jonathan C. L. Rodrigues, Christopher B. Lawton, Daniel Burden, Melissa Underhill, Matthew D. Kobetic, Zoe H. Adams, Jonathan C. W. Brooks, Angus K. Nightingale, Julian F. R. Paton, Mark C. K. Hamilton, Emma C. Hart
Review
Peripheral Vascular Disease
Thomas C. Hinton, Zoe H. Adams, Richard P. Baker, Katrina A. Hope, Julian F. R. Paton, Emma C. Hart, Angus K. Nightingale
Article
Radiology, Nuclear Medicine & Medical Imaging
Jonathan C. L. Rodrigues, Galina Strelko, Esther A. H. Warnert, Amy E. Burchell, Sandra Neumann, Laura E. K. Ratcliffe, Ashley D. Harris, Benjamin Chant, Ruth Bowles, Angus K. Nightingale, Richard G. Wise, Julian F. R. Paton, Emma C. Hart
EUROPEAN RADIOLOGY
(2020)
Article
Peripheral Vascular Disease
Matthew D. Kobetic, Amy E. Burchell, Laura E. K. Ratcliffe, Sandra Neumann, Zoe H. Adams, Regina Nolan, Angus K. Nightingale, Julian F. R. Paton, Emma C. Hart
Summary: The study found that untreated hypertensive men have lower sympathetic transduction compared to normotensive individuals, indicating that higher levels of MSNA are required to produce the same level of vasoconstrictor tone.
JOURNAL OF HUMAN HYPERTENSION
(2022)
Article
Peripheral Vascular Disease
Nathan E. Manghat, Elizabeth Robinson, Konstantina Mitrousi, Jonathan C. L. Rodrigues, Thomas Hinton, Julian F. R. Paton, Richard G. Wise, Angus K. Nightingale, Emma C. Hart
Summary: Variants in the posterior anatomy of the cerebral circulation are associated with hypertension and poor cerebral perfusion in young adults, indicating potential long-term consequences on cerebrovascular health.
Article
Cardiac & Cardiovascular Systems
Katrina Hope, Ben Chant, Thomas Hinton, Adrian H. Kendrick, Angus K. Nightingale, Julian F. R. Paton, Emma C. Hart
Summary: This study compared the V-E/VCO2 slope in patients with hypertension and normotensive individuals. It found that ventilatory efficiency is impaired in people with hypertension without heart failure. Future research is needed to determine if those hypertensive patients with elevated V-E/VCO2 slopes are at risk of developing heart failure.
JOURNAL OF THE AMERICAN HEART ASSOCIATION
(2023)
Article
Cardiac & Cardiovascular Systems
Zoe H. Adams, Hazel C. Blythe, Nisha Charkoudian, Timothy B. Curry, Michael J. Joyner, Adrian H. Kendrick, Angus K. Nightingale, Ana P. Abdala Sheikh, Emma C. Hart
Summary: Respiratory modulation of sympathetic nerve activity is reduced in postmenopausal females, which is associated with higher resting blood pressure.
AMERICAN JOURNAL OF PHYSIOLOGY-HEART AND CIRCULATORY PHYSIOLOGY
(2023)
Article
Cardiac & Cardiovascular Systems
Jonathan C. L. Rodrigues, Matthew F. R. Jaring, Melissa C. Werndle, Konstantina Mitrousi, Stephen M. Lyen, Angus K. Nightingale, Mark C. K. Hamilton, Stephanie L. Curtis, Nathan E. Manghat, Julian F. R. Paton, Emma C. Hart
JOURNAL OF CARDIOVASCULAR MAGNETIC RESONANCE
(2019)
Review
Clinical Neurology
Nisha Charkoudian, Emma C. J. Hart, Jill N. Barnes, Michael J. Joyner
CLINICAL AUTONOMIC RESEARCH
(2017)
Review
Neurosciences
Fiona D. McBryde, Emma C. Hart, Rohit Ramchandra, Julian F. R. Paton
AUTONOMIC NEUROSCIENCE-BASIC & CLINICAL
(2017)
Review
Cardiac & Cardiovascular Systems
Emma C. Hart, Geoffrey A. Head, Jason R. Carter, B. Gunnar Wallin, Clive N. May, Shereen M. Hamza, John E. Hall, Nisha Charkoudian, John W. Osborn
AMERICAN JOURNAL OF PHYSIOLOGY-HEART AND CIRCULATORY PHYSIOLOGY
(2017)