Epac2-dependent mobilization of intracellular Ca2+by glucagon-like peptide-1 receptor agonist exendin-4 is disrupted in β-cells of phospholipase C-ɛ knockout mice

DAPK1 Interaction with NMDA Receptor NR2B Subunits Mediates Brain Damage in Stroke

(2010) Weihong Tu et al.   CELL

Epac activation induces histone deacetylase nuclear export via a Ras-dependent signalling pathway

(2010) Mélanie Métrich et al.   CELLULAR SIGNALLING

Glucagon-Like Peptide (GLP)-1(9-36)Amide-Mediated Cytoprotection Is Blocked by Exendin(9-39) Yet Does Not Require the Known GLP-1 Receptor

(2010) Kiwon Ban et al.   ENDOCRINOLOGY

cAMP Mediators of Pulsatile Insulin Secretion from Glucose-stimulated Single β-Cells

(2010) Olof Idevall-Hagren et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

β-Arrestin–dependent activation of Ca2+/calmodulin kinase II after β1–adrenergic receptor stimulation

(2010) Supachoke Mangmool et al.   JOURNAL OF CELL BIOLOGY

Epac stimulation induces rapid increases in connexin43 phosphorylation and function without preconditioning effect

(2010) Nicolas Duquesnes et al.   PFLUGERS ARCHIV-EUROPEAN JOURNAL OF PHYSIOLOGY

Glucagon-Like Peptide 1—A Cardiologic Dimension

(2010) Marek Treiman et al.   TRENDS IN CARDIOVASCULAR MEDICINE

Glucose-dependent potentiation of mouse islet insulin secretion by Epac activator 8-pCPT-2’-O-Me-cAMP-AM

(2010) Grant G. Kelley et al.   Islets

Facilitation of β-cell KATPchannel sulfonylurea sensitivity by a cAMP analog selective for the cAMP-regulated guanine nucleotide exchange factor Epac

(2010) Colin A. Leech et al.   Islets

PKA-dependent potentiation of glucose-stimulated insulin secretion by Epac activator 8-pCPT-2′-O-Me-cAMP-AM in human islets of Langerhans

(2009) Oleg G. Chepurny et al.   AMERICAN JOURNAL OF PHYSIOLOGY-ENDOCRINOLOGY AND METABOLISM

Glucagon-like Peptide-1 and Myocardial Protection: More than Glycemic Control

(2009) Anjali V. Fields et al.   CLINICAL CARDIOLOGY

Enhanced Rap1 Activation and Insulin Secretagogue Properties of an Acetoxymethyl Ester of an Epac-selective Cyclic AMP Analog in Rat INS-1 Cells

(2009) Oleg G. Chepurny et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Reporting ethical matters inThe Journal of Physiology: standards and advice

(2009) Gordon B. Drummond   JOURNAL OF PHYSIOLOGY-LONDON

cAMP Analogs and Their Metabolites Enhance TREK-1 mRNA and K+ Current Expression in Adrenocortical Cells

(2009) J. A. Enyeart et al.   MOLECULAR PHARMACOLOGY

NAADP mobilizes calcium from acidic organelles through two-pore channels

(2009) Peter J. Calcraft et al.   NATURE

Identification of a chemical probe for NAADP by virtual screening

(2009) Edmund Naylor et al.   Nature Chemical Biology

The cAMP binding protein Epac regulates cardiac myofilament function

(2009) O. Cazorla et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

8-pCPT-2′-O-Me-cAMP-AM: An Improved Epac-Selective cAMP Analogue

(2008) Marjolein J. Vliem et al.   CHEMBIOCHEM

Cardioprotective and Vasodilatory Actions of Glucagon-Like Peptide 1 Receptor Are Mediated Through Both Glucagon-Like Peptide 1 Receptor–Dependent and –Independent Pathways

(2008) Kiwon Ban et al.   CIRCULATION

Epac Mediates β-Adrenergic Receptor–Induced Cardiomyocyte Hypertrophy

(2008) Mélanie Métrich et al.   CIRCULATION RESEARCH

Generation of Nicotinic Acid Adenine Dinucleotide Phosphate and Cyclic ADP-Ribose by Glucagon-Like Peptide-1 Evokes Ca2+ Signal That Is Essential for Insulin Secretion in Mouse Pancreatic Islets

(2008) B.-J. Kim et al.   DIABETES

Epac and Phospholipase Cϵ Regulate Ca2+Release in the Heart by Activation of Protein Kinase Cϵ and Calcium-Calmodulin Kinase II

(2008) Emily A. Oestreich et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Novel aspects of the molecular mechanisms controlling insulin secretion

(2008) Lena Eliasson et al.   JOURNAL OF PHYSIOLOGY-LONDON

Epac activation, altered calcium homeostasis and ventricular arrhythmogenesis in the murine heart

(2008) Sandeep S. Hothi et al.   PFLUGERS ARCHIV-EUROPEAN JOURNAL OF PHYSIOLOGY

Epac-selective cAMP analogs: New tools with which to evaluate the signal transduction properties of cAMP-regulated guanine nucleotide exchange factors

(2007) George G. Holz et al.   CELLULAR SIGNALLING