Article
Public, Environmental & Occupational Health
Kang Du, Hongyu Guan, Yunyun Zhang, Yuxiu Ding, Decai Wang
Summary: Cataract knowledge is low among older adults in rural China, and there is a low utilization of eye care services. Understanding cataract knowledge is associated with eye care utilization.
FRONTIERS IN PUBLIC HEALTH
(2022)
Review
Clinical Neurology
Hellen Araujo Nogueira, Caroline Tianeze de Castro, Danielle Cristina Guimaraes da Guimara, Marcos Pereira
Summary: Melatonin is a potential therapeutic intervention for improving sleep quality in people with ASD. The study found that the use of melatonin had a positive effect on total sleep time, sleep latency, and sleep efficiency in people with ASD.
PROGRESS IN NEURO-PSYCHOPHARMACOLOGY & BIOLOGICAL PSYCHIATRY
(2023)
Article
Multidisciplinary Sciences
Daniel Vethe, H. J. Drews, J. Scott, M. Engstrom, H. S. A. Heglum, J. Gronli, J. P. Wisor, T. Sand, S. Lydersen, K. Kjorstad, P. M. P. Faaland, C. L. Vestergaard, K. Langsrud, H. Kallestad
Summary: Evening exposure to blue-depleted light environments has been shown to significantly reduce the fragmentation and microarousals of REM sleep, without affecting the density or latency of REM sleep. This non-circadian effect of BDLE may have therapeutic potential in disorders characterized by fragmented REM sleep.
SCIENTIFIC REPORTS
(2022)
Article
Medicine, Research & Experimental
Yu Mi, Chaoqun Wei, Liyao Sun, Huirui Liu, Jiayue Zhang, Jialin Luo, Xiaohan Yu, Jie He, Hongyan Ge, Ping Liu
Summary: UVB-induced oxidative stress may enhance the sensitivity of lens epithelial cells to ferroptotic stress, leading to age-related cataracts.
BIOMEDICINE & PHARMACOTHERAPY
(2023)
Article
Ophthalmology
Lai-Chu See, Pei-Ru Li, Ken-Kuo Lin, Chiun-Ho Hou, Jiahn-Shing Lee
Summary: This study compared the incidence of insomnia after cataract surgery in pseudophakic eyes with blue light-filtering intraocular lenses (BFIOLs) and non-BF-IOLs. The results showed that there was no significant difference in the incidence rate of insomnia between the two IOL groups after up to 10 years of follow-up.
AMERICAN JOURNAL OF OPHTHALMOLOGY
(2022)
Review
Clinical Neurology
Emily J. Ricketts, Daniel S. Joyce, Ariel J. Rissman, Helen J. Burgess, Christopher S. Colwell, Leon C. Lack, Michael Gradisar
Summary: Light exposure plays a significant role in regulating circadian rhythms, and disruptions to this regulation can lead to various impairments. This is particularly relevant for adolescents, whose sleep-wake patterns are affected by reduced daytime light exposure and prolonged use of electronic devices in the evening. Implementing measures to adjust light intensity, spectra, duration, and delivery modality can support the sleep-wake health of adolescents in different contexts.
SLEEP MEDICINE REVIEWS
(2022)
Article
Multidisciplinary Sciences
Jiawei Yin, A. Agung Julius, John T. Wen
Summary: The circadian rhythm, governed by Process C and Process S, regulates various biological processes such as sleep and metabolism, determining the sleep-wake cycle. This paper introduces a method of regulating Process C and Process S through light exposure and sleep scheduling, solving the optimal synchronization problem for the two-process model, with the finding that joint optimization of light and sleep times can reduce synchronization time.
Article
Clinical Neurology
Barbara L. Parry, Charles J. Meliska, Diane L. Sorenson, L. Fernando Martinez, Ana M. Lopez, Sharron E. Dawes, Jeffrey A. Elliott, Richard L. Hauger
Summary: This study examined the effects of combined wake + light therapy on mood improvement in pregnant and postpartum depressed participants. The results showed that the PDI had better clinical efficacy for pregnant depressed participants, while the PAI had better clinical efficacy for postpartum depressed participants. The study also found that 2 weeks of light therapy was as effective as 6 weeks, and the improvement in mood for postpartum depressed participants was positively correlated with the phase advance of 6-SMT.
JOURNAL OF AFFECTIVE DISORDERS
(2023)
Review
Clinical Neurology
Daniel Chih Yung Cheng, James L. Ganner, Christopher J. Gordon, Craig L. Phillips, Ronald R. Grunstein, Maria Comas
Summary: Combined melatonin and bright light therapies have significant effects on improving sleep and circadian outcomes, with better efficacy in elderly populations compared to patients with delayed sleep-wake phase disorder. Adverse effects of melatonin in elderly populations should be carefully considered, and future studies should further investigate the separate and combined effects of these therapies in different target populations.
SLEEP MEDICINE REVIEWS
(2021)
Article
Biochemistry & Molecular Biology
Maria Dolores Hinchado, Eduardo Otero, Isabel Galvez, Leticia Martin-Cordero, Maria del Carmen Navarro, Eduardo Ortega
Summary: The aim of the study was to determine if the poor perceived sleep quality in FM patients could be corroborated by objective physiological determinations. The study found that FM patients reported poorer subjective sleep quality compared to the reference group, but there were no significant differences in objective determinations. The dysregulation of the stress response in FM patients may be associated with the delay in their resting circadian rhythm and difficulty falling asleep.
Article
Physiology
Riccardo Cremascoli, Davide Sparasci, Gianluca Giusti, Stefania Cattaldo, Elisa Prina, Fausto Roveta, Francesco Bruno, Cristina Ghezzi, Silvia Cerri, Marta Picascia, Sara Bernini, Elena Sinforiani, Michele Terzaghi, Lorenzo Priano, Alessandro Mauro, Raffaele Manni
Summary: This study investigates the effects of light therapy on sleep quality, mood, and cognition in patients with mild/moderate Alzheimer's disease. It is shown that light therapy tailored to the individual's circadian phase can induce a circadian phase shift, improve subjective sleep quality and cognitive performance, and shorten the time between dim light melatonin onset and falling asleep.
FRONTIERS IN PHYSIOLOGY
(2022)
Article
Multidisciplinary Sciences
Jade M. Murray, Michelle Magee, Tracey L. Sletten, Christopher Gordon, Nicole Lovato, Krutika Ambani, Delwyn J. Bartlett, David J. Kennaway, Leon C. Lack, Ronald R. Grunstein, Steven W. Lockley, Shantha M. W. Rajaratnam, Andrew J. K. Phillips
Summary: Two methods for predicting dim light melatonin onset (DLMO) in DSWPD patients, a dynamic model and a statistical model, were evaluated in this study. Both models performed well in predicting DLMO, indicating that circadian phase prediction from light data is a viable technique for improving screening, diagnosis, and treatment of DSWPD.
SCIENTIFIC REPORTS
(2021)
Review
Behavioral Sciences
Matthew Salanitro, Torsten Wrigley, Hisham Ghabra, Edward de Haan, Catherine M. Hill, Marco Solmi, Samuele Cortese
Summary: We conducted a systematic review and meta-analyses to assess the efficacy and tolerability of melatonin in individuals with sleep or mental health disorders. The study included 34 randomized control trials and found that melatonin significantly improved sleep onset latency and total sleep time in children/adolescents and adults with certain disorders. No significant differences in tolerability were observed between melatonin and placebo.
NEUROSCIENCE AND BIOBEHAVIORAL REVIEWS
(2022)
Article
Pharmacology & Pharmacy
Zhenxiang Gao, Maria Gorenflo, David C. Kaelber, Vincent M. Monnier, Rong Xu
Summary: Diabetes mellitus (DM) increases the risk of age-related cataracts, and there is currently no medication approved to delay cataract progression. Researchers used AI to search for drugs that could suppress cataract surgery. They combined AI-based candidate drug prediction with clinical data from electronic health records of cataract patients to identify potential drugs. Aspirin, melatonin, ibuprofen, and acetylcysteine were found to be associated with a reduced risk of cataract extraction in different diabetes patient groups. These drugs have the potential to delay cataract progression by inhibiting cyclooxygenase-2 (COX-2).
FRONTIERS IN PHARMACOLOGY
(2023)
Review
Biochemistry & Molecular Biology
Marta Waliszewska-Prosol, Marta Nowakowska-Kotas, Justyna Chojdak-Lukasiewicz, Slawomir Budrewicz
Summary: Migraine and sleep disorders are common chronic diseases with significant negative impacts on society and economy. The association between them is observed but not fully understood, with recent progress in understanding common anatomical structures and pathogenetic mechanisms. Better understanding of these mechanisms in the future will expand treatment options.
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
(2021)
