Article
Chemistry, Multidisciplinary
Zhiquan He, Tengda Rong, Yan Li, Junjie Ma, Quanshui Li, Furong Wu, Yuhang Wang, Fengping Wang
Summary: In this study, a facile synthesis method for bimetallic solid-solution MXene was reported, and its application in SERS detection was investigated. A free-standing film was prepared as the substrate, and a SERS enhancement factor of 10^12 and a femtomolar-level detection limit were achieved. The results indicated that the SERS activity of the TiVC-analyte system was dominated by the chemical mechanism (CM). This work provides guidance for the synthesis of 2D MXene and its application in ultrasensitive SERS detection.
Article
Chemistry, Physical
Mohammad Kamal Hossain, Qasem Ahmed Drmosh, Md Arifuzzaman
Summary: The size of plasmonic nanostructures affects the localization of electromagnetic fields and surface-enhanced Raman scattering (SERS) activity. In this study, silver nanoparticles (Ag-NPs), nanoneedles (Ag-NNs), and nanorings (Ag-NRs) were used to investigate the impact of near-field distributions on SERS. The results showed that Ag-NRs had the highest SERS activity. Through FESEM and FDTD analysis, the influence of electromagnetic field distributions on different sized nanostructures was revealed.
PHYSICAL CHEMISTRY CHEMICAL PHYSICS
(2022)
Article
Spectroscopy
Dechan Lu, Cairou Chen, Peipei Xu, Ruiyun You, Zhenzhen Lu, Yudong Lu
Summary: Accurate and sensitive detection of carcinoembryonic antigen (CEA) is crucial for healthcare and medical field. A novel CEA detection method using a sandwich type immunosensor based on surface-enhanced Raman scattering (SERS) was proposed, which showed high sensitivity, excellent selectivity, and low cost. The proposed immunosensor is a promising approach for high sensitivity quantification of CEA in liquid biopsy samples, with potential application in early cancer screening.
SPECTROCHIMICA ACTA PART A-MOLECULAR AND BIOMOLECULAR SPECTROSCOPY
(2023)
Article
Chemistry, Analytical
Junjie Chen, Suyang Li, Fuqi Yao, Wanbing Xu, Yunfeng Li, Qiang Chen, Pei Liang
Summary: In this study, a high-throughput method for the preparation of monodisperse submicron silver particles using S-shaped microfluidic chips was demonstrated. The particle size and morphology of the silver particles could be controlled by adjusting the concentration of the reducing agent ascorbic acid and the stabilizer PVP. The synthesized submicron silver particles showed ultra-sensitive SERS detection, with a detection limit of 10(-9) M for rhodamine 6G (R6G).
Article
Chemistry, Analytical
Yang Lu, Changbiao Zhan, Liandong Yu, Yiyue Yu, Huakun Jia, Xiaozhe Chen, Dongzhi Zhang, Rongke Gao
Summary: We developed a novel multifunctional nanocone array as a solid immunoassay plate and SERS substrate for the simultaneous detection of PSA and thrombin based on a microfluidic chip. Compared to traditional immunoassays, this nanocone array with a deposited gold film provides a larger surface area for efficient target antigen capture. By integrating this microfluidic chip, we achieved simultaneous detection of PSA and thrombin with high sensitivity. This detection strategy shows great potential for early prostate cancer diagnosis.
SENSORS AND ACTUATORS B-CHEMICAL
(2023)
Article
Chemistry, Physical
Yasemin Celik, Ayse Kurt
Summary: Hybrid SERS substrates combining noble metal nanoparticles and graphene-based materials offer a stable and cost-effective platform for SERS analysis, which shows great potential to promote the application of SERS for routine analyses.
APPLIED SURFACE SCIENCE
(2021)
Article
Nanoscience & Nanotechnology
Cheng-Zhe Xie, Cheng-Han Li, You-Chia Chang, Yih-Fan Chen
Summary: This paper introduces a gel-based 3D substrate for enhanced SERS detection by utilizing photonic nanojets (PNJs). The porous structure of the gel-based substrate allows small molecules to diffuse, while silica beads on the surface generate PNJs during SERS measurements. By coating the substrate with a close-packed array of silica beads, multiple PNJs can be generated, resulting in significantly enhanced Raman signals and improved detection sensitivity. This enhancement scheme can be applied to achieve high-sensitivity SERS detection for various molecules in diverse applications.
ACS APPLIED MATERIALS & INTERFACES
(2023)
Article
Chemistry, Multidisciplinary
Dingyu Song, Tianxing Wang, Lin Zhuang
Summary: Surface-enhanced Raman scattering (SERS) technology is important in spectroscopy. The combination of spin-coating, surface modification, and in situ reduction methods was used to prepare a photonic crystal array of SiO2@Au core-shell nanoparticles as a SERS substrate (SiO2@Au NP array). Compared to a Au-SiO2 NP array prepared using doping methods, the SiO2@Au NP array showed better SERS properties and reproducibility. The approach provides a new option for SERS substrate preparation and has potential applications in trace contaminant detection and nondestructive testing.
Article
Chemistry, Analytical
Xuefang Gu, Shu Tian, Yiyang Chen, Yuxin Wang, Dandan Gu, Enhui Guo, Ying Liu, Jianguo Li, Anping Deng
Summary: The SERS-based competitive immunoassay for detecting beta-adrenergic agonists was developed using highly ordered gold cavity arrays, achieving high sensitivity and recoveries. Introduction of long DNA concatamers and silver staining can enhance the sensitivity, making it a new efficient and sensitive detection method.
SENSORS AND ACTUATORS B-CHEMICAL
(2021)
Article
Chemistry, Multidisciplinary
Zixun Jia, Sarah Asiri, Asma Elsharif, Widyan Alamoudi, Ebtesam Al-Suhaimi, Sang-Gook Kim
Summary: This work reports a new design of SERS substrate for enhanced Raman spectroscopy, providing high sensitivity and fast contact with target structures for immunomagnetic bacteria detection. The substrate uses transparent PDMS inverted nanocone arrays to guide light to plasmonic gold nanorods at the cone tips, increasing photon density at the hotspots.
APPLIED SCIENCES-BASEL
(2021)
Article
Instruments & Instrumentation
Lan Zhang, Shiying Wu, Tingting Zhang, Anqi Li, Gongying Wang, Lingling Wang, Chang Liu, Weihua Li, Jiansheng Li, Rui Lu
Summary: By calcining titanium dioxide (TiO2) precursors at different temperatures, crystallized TiO2 (c-TiO2) and amorphous TiO2 (a-TiO2) nanosheets were generated for investigating the chemical enhancement of semiconductors and increasing the sensitivity of the surface-enhanced Raman spectroscopy (SERS) substrate. A two-dimensional a-TiO2/Ag nanosheet SERS substrate was successfully fabricated, and it showed highly sensitive and repeatable Raman signals compared to c-TiO2 or Ag nanoparticles alone.
APPLIED SPECTROSCOPY
(2023)
Article
Chemistry, Multidisciplinary
Bjoern K. Birdsong, Billy W. Hoogendoorn, Fritjof Nilsson, Richard L. Andersson, Antonio J. Capezza, Mikael S. Hedenqvist, Stefano Farris, Antonio Guerrero, Richard T. Olsson
Summary: Graphene oxide (GO) was used as a template to synthesize silicon oxide (SiOx) based 2D-nanomaterials with similar morphological features as the GO sheets. By controlled condensation reaction with low concentrations of GO, 2D-nanoflakes consisting of GO-flakes coated with a silica precursor were obtained. The GO template was fully removable without affecting the nanoflake morphology, providing a method for large-scale preparation of SiOx-based 2D nanosheets.
Article
Chemistry, Analytical
Siqi Huang, Caijun Wu, Yuying Wang, Xia Yang, Ruo Yuan, Yaqin Chai
Summary: The Ag/TiO2 nanocomposites were prepared via catalytic hairpin assembly (CHA) strategy to fabricate a SERS biosensor for sensitive detection of UDG, with the introduction of Pb2+ assisted DNAzyme cleavage reaction enhancing the sensitivity of the method, achieving a detection limit of 1.2×10-5 U mL-1.
SENSORS AND ACTUATORS B-CHEMICAL
(2021)
Article
Spectroscopy
Dipanwita Majumdar, Subhajit Jana, Samit Kumar Ray
Summary: In this study, a nanohybrid SERS platform was developed by decorating two-dimensional WSe2 flakes with zero-dimensional Au NPs. The hybrid structure exhibited promising SERS activity with a detection limit as low as 10(-9) M, along with reliable signal stability and reproducibility. These results indicate the great potential of the nanohybrid structure in SERS applications.
SPECTROCHIMICA ACTA PART A-MOLECULAR AND BIOMOLECULAR SPECTROSCOPY
(2022)
Article
Spectroscopy
Dechan Lu, Rongyuan Cai, Yuqin Liao, Ruiyun You, Yudong Lu
Summary: In this study, a simple, efficient, and label-free surface enhanced Raman scattering (SERS) method was developed for the detection of uric acid (UA) content. The method showed a linear response to UA and good recoveries were obtained for the sensing of sweat. Therefore, the developed SERS substrate has potential applications in healthcare monitoring.
SPECTROCHIMICA ACTA PART A-MOLECULAR AND BIOMOLECULAR SPECTROSCOPY
(2023)
Article
Chemistry, Multidisciplinary
Yong Dou, Charles A. Cartier, Wenjie Fei, Shashank Pandey, Sepideh Razavi, Ilona Kretzschmar, Kyle J. M. Bishop
Article
Engineering, Environmental
Megan Webster, Hae Yang Lee, Kristi Pepa, Nathan Winkler, Ilona Kretzschmar, Marco J. Castaldi
WASTE MANAGEMENT & RESEARCH
(2018)
Article
Chemistry, Multidisciplinary
Zohreh Jalilvand, Amar B. Pawar, Ilona Kretzschmar
Article
Chemistry, Multidisciplinary
Thomas W. Long, Ubaldo M. Cordova-Figueroa, Ilona Kretzschmar
Article
Chemistry, Multidisciplinary
Sepideh Razavi, Binhua Lin, Ka Yee C. Lee, Raymond S. Tu, Ilona Kretzschmar
Article
Nanoscience & Nanotechnology
Ellen M. Knapp, Raymond R. Dagastine, Raymond S. Tu, Ilona Kretzschmar
ACS APPLIED MATERIALS & INTERFACES
(2020)
Article
Chemistry, Multidisciplinary
Sayan Das, Zohreh Jalilvand, Mihail N. Popescu, William E. Uspal, Siegfried Dietrich, Ilona Kretzschmar
Article
Chemistry, Multidisciplinary
Zohreh Jalilvand, Hamad Haider, Jingqin Cui, Ilona Kretzschmar
Article
Engineering, Chemical
Megan M. Webster, Michael Lugo-Pimentel, Ilona Kretzschmar, Marco J. Castaldi
INDUSTRIAL & ENGINEERING CHEMISTRY RESEARCH
(2020)
Editorial Material
Chemistry, Multidisciplinary
Ilona Kretzschmar, Maria M. Santore
Article
Chemistry, Physical
Jonathan A. Victoria-Camacho, Ronal A. DeLaCruz-Araujo, Ilona Kretzschmar, Ubaldo M. Cordova-Figueroa
Article
Chemistry, Multidisciplinary
Paulina Librizzi, Aneek Biswas, Roger Chang, Xiang-Tian Kong, Matthew Moocarme, Gaurav Ahuja, Ilona Kretzschmar, Luat T. Vuong
Article
Chemistry, Physical
Gabriel I. Vega-Bellido, Ronal A. DeLaCruz-Araujo, Ilona Kretzschmar, Ubaldo M. Cordova-Figueroa
Article
Chemistry, Physical
Jingqin Cui, Deng Long, Pavel Shapturenka, Ilona Kretzschmar, Xinyi Chen, Taihong Wang
COLLOIDS AND SURFACES A-PHYSICOCHEMICAL AND ENGINEERING ASPECTS
(2017)
Proceedings Paper
Engineering, Electrical & Electronic
Nicholas V. Proscia, Matthew Moocarme, Ilona Kretzschmar, Vinod M. Menon, Luat T. Vuong
2016 CONFERENCE ON LASERS AND ELECTRO-OPTICS (CLEO)
(2016)