Review
Chemistry, Multidisciplinary
Rengan Luo, Da Zhu, Huangxian Ju, Jianping Lei
Summary: Electrochemiluminescence (ECL) is a powerful technique that relies on charge transfer between electrochemical intermediates and co-reactants/emitters to form excited emitters. The development of molecular nanocrystals, such as metal-organic frameworks (MOFs) and covalent organic frameworks (COFs), has allowed for the exploration of ECL mechanisms and enhancement strategies. Reticular crystalline nanoemitters with different topologies provide a platform for understanding ECL fundamentals and designing next-generation ECL devices.
ACCOUNTS OF CHEMICAL RESEARCH
(2023)
Article
Biochemical Research Methods
Huixin Zhang, Lin Du, Zhihao Wei, Xuemei Wang, Neso Sojic, Xin Zhou, Zonghua Wang
Summary: In this study, high-intensity focused ultrasound (HIFU) was introduced as a pretreatment method to enhance the electrochemiluminescence (ECL) signal of luminol without the need for exogenous co-reactants. The in situ generation of superoxide anion (O-2(-center dot)) by HIFU was found to be the key initiator for boosting the ECL emission, providing a promising strategy for ultrasensitive ECL detection in the analysis of complex biological entities.
ANALYTICAL AND BIOANALYTICAL CHEMISTRY
(2022)
Article
Chemistry, Analytical
Yunxiu Jia, Li Zhang, Weijiang Guan, Chao Lu
Summary: Vesicles, such as multilamellar vesicles obtained from sodium bis(2-ethylhexyl) sulfosuccinate (AOT), were found to significantly enhance the electrochemiluminescence (ECL) performance. These vesicles could improve the electron transfer and reaction rate, as well as the stability of intermediate species, leading to enhanced ECL signals. The versatility of vesicle-modified microenvironment for ECL signal amplification was further verified using dodecyl dimethyl(3-sulfopropyl) ammonium hydroxide inner salt (DSB)-based vesicle.
ANALYTICAL CHEMISTRY
(2023)
Article
Chemistry, Analytical
Alessandra Zanut, Marianna Rossetti, Massimo Marcaccio, Francesco Ricci, Francesco Paolucci, Alessandro Porchetta, Giovanni Valenti
Summary: In this study, we investigated the mechanism of ECL signal generation at the nanoscale using DNA nanoswitches with different stem stabilities. By tuning the stability of the DNA nanoswitches, we were able to activate different ECL mechanisms, achieve a digital-like association curve, and increase signal gain significantly while maintaining low detection limits. Our findings demonstrate the potential for designing customized DNA devices for highly efficient dual-signal-output ratiometric-like ECL systems.
ANALYTICAL CHEMISTRY
(2021)
Article
Chemistry, Analytical
Yongjun Zheng, Hong Yang, Lufang Zhao, Yuhan Bai, Xinghua Chen, Kaiqing Wu, Songqin Liu, Yanfei Shen, Yuanjian Zhang
Summary: This research presents a general strategy to induce luminescence in ECL-inactive dyes in an aqueous solution using grafting, a well-developed concept for plant propagation. By grafting ECL emitters, a series of emitters with near-unity resonance energy transfer (RET) efficiency and tunable emission wavelengths were obtained. Each unit in the proposed ECL ensemble maximally functioned, leading to the establishment of a three-dimensional coordinate biosensing system with calibration curve and selectivity simultaneously displayed.
ANALYTICAL CHEMISTRY
(2022)
Article
Chemistry, Physical
Haiping Pan, Jinhao Zhou, Si Liu
Summary: This study demonstrates that visible room temperature electrochemiluminescence (ECL) can be directly modulated via magnetic field effects on the spin evolution in electrochemical-generated radical pairs. By altering the initial spin multiplicity of the radical pairs through varying applied electrode potentials, negative and positive magnetic field effects on electrochemiluminescence (MFEECL) can be generated, paving the way for the design of magnetic-field-manipulated electroluminescent devices.
JOURNAL OF PHYSICAL CHEMISTRY C
(2023)
Article
Electrochemistry
Mohammad Ali Kamyabi, Mohsen Moharramnezhad, Nasim Hajari
Summary: A new enzyme-free electrochemiluminescence glucose sensor was developed based on copper oxide nanoparticles modified Ni-foam electrode, offering wide linear dynamic range and low limit of detection for accurate detection of glucose in blood serum samples.
JOURNAL OF THE ELECTROCHEMICAL SOCIETY
(2021)
Article
Biochemistry & Molecular Biology
Kaiyun Ji, Jinpeng Shan, Xing Wang, Xiaoli Tan, Jingli Hou, Yangping Liu, Yuguang Song
Summary: This study introduces a novel strategy for designing near-infrared O2?- fluorescent probes with high self-stability and sensitivity to O2?-. The probes can image O2?- generation in various cells and show potential in drug toxicity evaluation.
FREE RADICAL BIOLOGY AND MEDICINE
(2021)
Article
Engineering, Environmental
Qiang Bi, Sisi Jiang, Changfeng Hu, Li Zhang, Yilin Zhao, Bo Yang, Guoping Li, Juanqin Xue
Summary: In this study, a N/Co-co-doped graphite gas diffusion electrode (Co-NG GDE) has been prepared and applied in the E-peroxone system. Surprisingly, Co-NG GDE exhibits the highest degradation efficiency for phenol and oxalate, despite its poor performance in the ORR to H2O2. The abundance of O2(center dot-) produced by Co-NG GDE, due to its higher pyridine-N content, can replace H2O2 to form super-active center dot OH.
JOURNAL OF ENVIRONMENTAL CHEMICAL ENGINEERING
(2023)
Article
Chemistry, Multidisciplinary
Tsz-Kan Ma, Diyuan Li, Jonathan D. Wilden
Summary: Mechanistic studies of a reactive oxygen species mediated electrochemical radical reaction of alkyl iodides are described. Hydroxyl radicals and ozone are identified as the active species involved in the formation of alkyl radicals under mildly reducing potential (-1.0 V vs. Ag QRE) in buffered acidic conditions (pH 3.6).
CHEMICAL COMMUNICATIONS
(2021)
Article
Chemistry, Analytical
Yuxi Wei, Jian Zhang, Xiaolin Yang, Zimei Wang, Junxia Wang, Honglan Qi, Chengxiao Zhang
Summary: This study reports the performance enhancement strategies for magnetic beads (MBs)-based electro-chemiluminescence (ECL) platforms. Double magnetic field actuation of the ECL magnetic micro-biosensors (MMbiosensors) greatly enhances sensitivity for cancer biomarker and exosomes detection. The strategies include using a diamagnetic PMT, circular-disc magnets lain-in glassy carbon electrode, and external magnet actuation for pre-concentration of MBs. The developed strategies increase the sensitivity of ECL MMbiosensors by 45-fold for fundamental research and 33-fold for the detection of prostate specific antigen (PSA) and exosomes.
Article
Chemistry, Physical
Yu B. Tsaplev, A. Trofimov
Summary: Quantum yields for luminol and Fe-II in the chemiluminescence of luminol initiated by Fe-II salt solutions were determined. It was concluded that chemiluminescence is not initiated by superoxide anion but by a more efficient primary oxidant. Quenching experiments with dimethyl sulfoxide indicated that hydroxyl radical is also not a primary oxidant. The effect of chelation of Fe-II by EDTA on chemiluminescence was found to be unrelated to the loss of initiating action of Fe(II)EDTA in the luminol chemiluminescence.
RUSSIAN JOURNAL OF PHYSICAL CHEMISTRY A
(2022)
Article
Engineering, Environmental
Kefeng Shang, Rino Morent, Ning Wang, Yongxin Wang, Bangfa Peng, Nan Jiang, Na Lu, Jie Li
Summary: The study shows that persulfate can enhance the degradation of sulfamethoxazole in a water falling film dielectric barrier discharge plasma reactor, with PMS performing better than PDS. Increasing the applied voltage, solution pH, and PMS/PDS concentration promotes SMX degradation. The reactive species generated from the activation of PMS/PDS by discharge plasma play a key role in SMX degradation, with center dot OH and SO4 center dot- being particularly important.
CHEMICAL ENGINEERING JOURNAL
(2022)
Article
Engineering, Electrical & Electronic
Kohei Sakanoue, Andrea Fiorani, Irkham, Yasuaki Einaga
Summary: Electrogenerated chemiluminescence (ECL) is a phenomenon triggered by an electrochemical reaction, highly dependent on electrode material and surface state. Boron-doped diamond (BDD) has potential for ECL applications, with the amount of boron doping affecting the electrochemical response, but thorough investigation is lacking. Results suggest that the suitable boron doping level and surface state for BDD electrode vary depending on the ECL system, emphasizing the importance of proper electrode selection.
ACS APPLIED ELECTRONIC MATERIALS
(2021)
Article
Chemistry, Analytical
Fuad Abduro Bushira, Shimeles Addisu Kitte, Chen Xu, Haijuan Li, Lirong Zheng, Ping Wang, Yongdong Jin
Summary: In this study, the ECL response of the iron SAC-based system was significantly enhanced for the first time by exciting two-dimensional plasmons derived from the AugSiO(2) nanomembrane. The Fe-SAC ECL system was successfully applied for the detection of dopamine, hemin, and mercury with low limits of detection and wider linear ranges under optimal conditions.
ANALYTICAL CHEMISTRY
(2021)
Correction
Engineering, Chemical
Larah Kriselle B. Paragas, Van Dien Dang, Rama Shanker Sahu, Sergi Garcia-Segura, Mark Daniel G. de Luna, Jose Antonio I. Pimentel, Ruey-An Doong
SEPARATION AND PURIFICATION TECHNOLOGY
(2023)
Editorial Material
Green & Sustainable Science & Technology
Alexsandro J. dos Santos, Haruna L. Barazorda-Ccahuana, Griselda Caballero-Manrique, Yvens Cheremond, Patricio J. Espinoza-Montero, J. Ricardo Gonzalez-Rodriguez, Ulises J. Jauregui-Haza, Marcos R. V. Lanza, Andrea Najera, Carla Oporto, Andres Perez Parada, Tzayam Perez, Valeria Delgado Quezada, Veronica Rojas, Velia Sosa, Abdoulaye Thiam, Ricardo A. Torres-Palma, Ronald Vargas, Sergi Garcia-Segura
NATURE SUSTAINABILITY
(2023)
Correction
Green & Sustainable Science & Technology
Alexsandro J. dos Santos, Haruna L. Barazorda-Ccahuana, Griselda Caballero-Manrique, Yvens Cheremond, Patricio J. Espinoza-Montero, J. Ricardo Gonzalez-Rodriguez, Ulises J. Jauregui-Haza, Marcos R. V. Lanza, Andrea Najera, Carla Oporto, Andres Perez Parada, Tzayam Perez, Valeria Delgado Quezada, Veronica Rojas, Velia Sosa, Abdoulaye Thiam, Ricardo A. Torres-Palma, Ronald Vargas, Sergi Garcia-Segura
NATURE SUSTAINABILITY
(2023)
Article
Biochemistry & Molecular Biology
Sergio Garcia-Segura, Javier del Rey, Laia Closa, Iris Garcia-Martinez, Carlos Hobeich, Ana Belen Castel, Francisco Vidal, Jordi Benet, Maria Oliver-Bonet
Summary: Since the first description of a commensal seminal microbiome using sequencing, less than a decade ago, interest in the composition of this microbiome and its relationship with fertility has been growing. Articles using next-generation sequencing techniques agree on the identification of the most abundant bacterial phyla. However, at the genus level, there is still no consensus on which bacteria are most abundant in human seminal plasma.
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
(2023)
Article
Engineering, Chemical
Omar Alrehaili, Ana S. Fajardo, Sergi Garcia-Segura, Paul Westerhoff
Summary: Innovations in reactor geometry can lower energy requirements for electrolysis and degrade environmental pollutants. Microfluidic devices with high electrode surface area to solution volume ratios minimize mass transfer limitations and decrease energy requirements.
SEPARATION AND PURIFICATION TECHNOLOGY
(2023)
Review
Engineering, Environmental
Gamze Ersan, Gabriel Antonio Cerron-Calle, Mahmut S. Ersan, Sergi Garcia-Segura
Summary: Adsorptive separation technologies are effective in removing organic contaminants from aqueous water. The breakthrough of contaminants pose a challenge in regeneration of spent adsorbents. Electrochemically induced regeneration has the potential to overcome these challenges and provide a sustainable solution. This review critically evaluates the fundamental aspects of in situ electro-regeneration for spent carbons and discusses specific examples related to emerging contaminants.
Review
Nanoscience & Nanotechnology
Kuichang Zuo, Sergi Garcia-Segura, Gabriel A. Cerron-Calle, Feng-Yang Chen, Xiaoyin Tian, Xiaoxiong Wang, Xiaochuan Huang, Haotian Wang, Pedro J. J. Alvarez, Jun Lou, Menachem Elimelech, Qilin Li
Summary: Electrified processes provide a chemical-free solution for removing a wide range of contaminants from water, including those difficult to treat using conventional methods. This review presents the principles of several electrified water treatment processes and emphasizes the importance of electrode materials in contaminant transport and transformation.
NATURE REVIEWS MATERIALS
(2023)
Article
Chemistry, Physical
Gabriel Antonio Cerron-Calle, Annika Wines, Sergi Garcia-Segura
Summary: Electrochemical reduction of nitrate provides a green alternative for ammonia production, and Ni/Co(OH)x and Ni/Cu2O/Co(OH)x interfaces demonstrate high competitiveness as PGM-free electrocatalyst. The synergistic effects and mechanisms of direct charge transfer reduction and catalytic hydrogenation contribute to the high conversion rate of nitrate. The stability evaluation shows that the electrocatalyst has high activity retention and negligible metal leaching.
APPLIED CATALYSIS B-ENVIRONMENTAL
(2023)
Article
Electrochemistry
Renato Montenegro-Ayo, Tzayam Perez, Marcos R. V. Lanza, Enric Brillas, Sergi Garcia-Segura, Alexsandro J. dos Santos
Summary: This paper presents the performance evaluation of a novel pre-pilot reactor design using boron-doped diamond (BDD) anode for electrochemical oxidation of emerging pollutants. The reactor's engineering capabilities were assessed using turbulent flow simulation and secondary current distribution modeling. Different medium conditions were tested to determine the degradation efficiency of the reactor towards the model pollutant, ciprofloxacin (CIP). The study showed that the reactor achieved almost complete mineralization of CIP, with the majority of its nitrogen converted into nitrate.
ELECTROCHIMICA ACTA
(2023)
Article
Environmental Sciences
Gabriel Antonio Cerron-Calle, Ana S. Fajardo, Jingyue Liu, Carlos M. Sanchez-Sanchez, Sergi Garcia-Segura
Summary: Fertilizers are crucial in the food-energy-water nexus. The electrocatalytic nitrate reduction for ammonia production is a promising alternative to centralized processes. However, the challenge lies in finding affordable and selective electrocatalysts.
SCIENCE OF THE TOTAL ENVIRONMENT
(2023)
Article
Engineering, Chemical
Ana S. Fajardo, Paul Westerhoff, Sergi Garcia-Segura, Carlos M. Sanchez-Sanchez
Summary: This article discusses how electrolyte engineering can control the selectivity and kinetics of electrochemical reduction of nitrate (ERN). The presence of different alkali cations in the solution has a significant impact on the removal rate of nitrate and the product selectivity. By tuning the electrode-electrolyte interface with suitable cations, a significant shift in product selectivity from Ngas to ammonia production can be achieved. Additionally, solutions containing Cs+ show a approximately 2-fold decrease in electrical energy per order compared to solutions containing Li+.
SEPARATION AND PURIFICATION TECHNOLOGY
(2023)
Article
Chemistry, Multidisciplinary
Andre L. Magdaleno, Gabriel A. Cerron-Calle, Alexsandro J. dos Santos, Marcos R. V. Lanza, Onur G. Apul, Sergi Garcia-Segura
Summary: This study proposes the use of oxygen nanobubbles to enhance the gas efficiency of electrogeneration of H2O2, and finds that nanobubbles have a higher gas-liquid mass transfer coefficient compared to macrobubbles. Additionally, the reaction yield of electrogeneration of H2O2 is improved under the influence of nanobubbles.
Article
Environmental Sciences
Gabriel Antonio Cerron-Calle, Alexsandro J. dos Santos, Marcos R. V. Lanza, Ming-Chun Lu, Sergi Garcia-Segura
Summary: The presence of arsenic in groundwater is a barrier to accessing safe clean water for everyone, even at low concentrations it poses a high risk to human health. Electrified technologies such as electrocoagulation, electrodialysis, and electrosorption are emerging as decentralised water treatment alternatives to manage arsenic pollution. This article presents the principles, limitations, and technology readiness level classification of these upcoming systems, and discusses the challenges associated with the difference between environmental arsenic concentrations and lab-scale tested concentrations. Finally, an outlook and perspective are provided.
CURRENT OPINION IN ENVIRONMENTAL SCIENCE & HEALTH
(2023)
Article
Engineering, Environmental
Enric Brillas, Sergi Garcia-Segura
Summary: Photoelectrocatalysis (PEC) is an electrochemical advanced oxidation process that combines photocatalysis and electrolysis. It utilizes semiconductor photocatalysts to generate electron-hole pairs and oxidation species for the removal of organic pollutants. This paper provides a comprehensive review of the application of PEC with TiO2 photoanodes for wastewater treatment, discussing the fundamentals, operating variables, recent advances, and future prospects of this technique.
JOURNAL OF ENVIRONMENTAL CHEMICAL ENGINEERING
(2023)
Article
Engineering, Chemical
Raul Jose Alves Felisardo, Enric Brillas, Eliane Bezerra Cavalcanti, Sergi Garcia-Segura
Summary: This study reports the remediation of CIP in synthetic urine using electrochemical oxidation with a boron-doped diamond (BDD) anode. The results show that the ECO process with a BDD anode generates hydroxyl radicals and free chlorine as effective oxidants for CIP removal. Uric acid is completely oxidized, while urea and creatinine are partially destroyed. The TOC reduction rate is moderate under specific pH and current density conditions.
SEPARATION AND PURIFICATION TECHNOLOGY
(2024)
