Article
Chemistry, Multidisciplinary
Shingo Hirashima, Soyoung Park, Hiroshi Sugiyama
Summary: Forster resonance energy transfer (FRET) is a useful tool for understanding biomolecular dynamics, and FRET-based analysis of nucleosomes has the potential to bridge the gap between static structures and dynamic cellular behaviors. Nucleoside-based FRET pairs offer advantages over traditional pairs, as they can be incorporated into the helical structures of nucleic acids. This study investigates the construction of nucleosomes with nucleobase FRET pairs and analyzes experimental and theoretical FRET efficiencies using fluorescence spectroscopy and molecular dynamics simulations, respectively. The results show distinguishable experimental FRET efficiencies depending on the positions of FRET pairs in nucleosomal DNA, which are supported by theoretical calculations. This research suggests the possibility of using this approach to analyze structural changes in nucleosomes caused by epigenetic modifications or internucleosomal interactions.
CHEMISTRY-A EUROPEAN JOURNAL
(2023)
Article
Biochemistry & Molecular Biology
Alexey S. Gavrikov, Nina G. Bozhanova, Mikhail S. Baranov, Alexander S. Mishin
Summary: This study introduces a modulated FRET acceptor that simplifies one-channel FRET measurement by using a cell-permeable chromophore to decrease the fluorescence of the donor-fluorescent protein. The chemically modulated FRET acceptor is compatible with live-cell experiments and allows for prolonged time-lapse experiments with dynamic energy transfer evaluation.
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
(2022)
Article
Chemistry, Applied
Yoliztli Banales-Leal, Andrea Garcia-Rodriguez, Fabian Cuetara-Guadarrama, Mireille Vonlanthen, Kendra Sorroza-Martinez, David Morales-Morales, Ernesto Rivera
Summary: A novel series of dendritic compounds with peripheral pyrene groups and a porphyrin core were synthesized and characterized in this study. Metallation with Zn(II) and Mg(II) resulted in red shifts in the Soret absorption band and blue shifts in the emission band for the dendritic porphyrins, with all compounds exhibiting high energy transfer efficiency.
Article
Nanoscience & Nanotechnology
J. A. Rivera, K. V. Desai, J. G. Eden
Summary: By utilizing the SPB biocomplex, several FRET lasers have been realized, with the Cy3-SPB-Cy5 conjugate demonstrating narrow bandwidth and low threshold pump energy, expanding the potential applications in biomedical diagnostics.
Article
Chemistry, Multidisciplinary
Yihang Zhang, Guilong Cai, Yawen Li, Zhenzhen Zhang, Tengfei Li, Xia Zuo, Xinhui Lu, Yuze Lin
Summary: The introduction of BTPR as a third component in organic solar cells reduces the trap density, leading to significant improvements in PCE and energy loss. This offers new possibilities for achieving higher efficiency solar cells.
ADVANCED MATERIALS
(2021)
Article
Chemistry, Multidisciplinary
S. Roth, P. T. Trinh, J. Wachtveitl
Summary: The photophysics of an inorganic/organic hybrid system were studied, focusing on increasing the two-photon efficiency of photoresponsive systems. The CdS/ZnS core/shell quantum dots and coumarin derivatives demonstrated a highly efficient Forster resonance energy transfer mechanism, even after two-photon excitation.
Article
Optics
Smita Dey, Asit Kumar Kar
Summary: The optical properties of luminescent PMMA-ZnO nanocomposites are affected by the variation of ZnO concentration, which decreases emission intensity but increases energy transfer efficiency as ZnO concentration increases. The photoluminescence quantum efficiency of the composite with highest emission is 74%.
OPTICS AND LASER TECHNOLOGY
(2021)
Article
Chemistry, Applied
Andrea Garcia-Rodriguez, Pasquale Porcu, Aldo S. Estrada-Montano, Mireille Vonlanthen, Ricardo D. Martinez-Serrano, Gerardo Zaragoza-Galan, Ernesto Rivera
Summary: A novel series of systems with pyrene and bodipy groups were reported, showing high FRET efficiencies and potential for fluorescence resonance energy transfer applications.
Article
Biochemistry & Molecular Biology
Robert Eckenstaler, Ralf A. Benndorf
Summary: Protein-protein interaction studies provide insights into the formation of complexes, regulation of enzymatic activity, and information transfer within cells. FRET microscopy is a powerful tool for non-invasive investigation of these interactions, allowing for analysis of multiple interacting proteins simultaneously. By combining different FRET data acquisition and interpretation methods, it is possible to distinguish between different types of protein-protein interactions in living cells.
FRONTIERS IN MOLECULAR BIOSCIENCES
(2021)
Article
Materials Science, Multidisciplinary
Dhritiman Banerjee, Asit Kumar Kar
Summary: Surface modification of ZnO nanoparticles using polymer can alter their optoelectronic properties, but at the cost of decreased quantum efficiency. Research on polymer-capped ZnO nanoparticles must consider factors such as spectral overlap between ZnO and polymer, FRET, and exciton diffusion.
Article
Chemistry, Physical
Priyanka Mishra, Pichiah Saravanan, Gopinath Packirisamy
Summary: Researchers have developed a novel FRET-active ZnO/Ag@Ag4V2O7 hybrid material for promoting the photocatalytic oxidation of methane. This hybrid material enhances the photoredox ability through FRET and has a higher positive potential, facilitating the methane oxidation reaction. Experimental results show that the photocurrent density of this material under visible illumination is 300 times higher than that of the individual materials, and it exhibits good apparent quantum efficiency and solar-to-fuel efficiency.
INTERNATIONAL JOURNAL OF HYDROGEN ENERGY
(2023)
Article
Chemistry, Organic
Eduardo Izquierdo, Mireia Casasampere, Gemma Fabrias, Jose Luis Abad, Josefina Casas, Antonio Delgado
Summary: The suitability of two bichromophoric 1-deoxydihydroceramides as FRET probes, containing a labelled spisulosine derivative and two differently omega-labelled fluorescent palmitic acids, has been evaluated. The metabolic incorporation of omega-azido palmitic acid into the labeled spisulosine to produce omega-azido 1-deoxyceramide via ceramide synthase (CerS) has been studied. Optimization of the strain-promoted click reaction between the omega-azido 1-deoxyceramide and suitable fluorophores has enabled the development of the target bichromophoric 1-deoxydihydroceramides, paving the way for FRET-based assays for studying sphingolipid metabolism.
ORGANIC & BIOMOLECULAR CHEMISTRY
(2021)
Article
Chemistry, Multidisciplinary
Muhammad Mubeen, Noor ul Ain, Muhammad Adnan Khalid, Maria Mukhtar, Bushra Naz, Zumaira Siddique, Anwar Ul-Hamid, Azhar Iqbal
Summary: In this article, the band gap of ternary ZnCdS quantum dots (QDs) is tuned by changing the concentration of the capping ligand, mercaptoacetic acid (MAA). The functionalization of QDs controls their size and band gap, resulting in a blue shift in the absorption and photoluminescence (PL) spectra. The combination of MAA-functionalized QDs and ensulizole sunscreen exhibits a very high energy transfer efficiency (E) of approximately 70%.
Article
Chemistry, Physical
Hongxiao Xiang, Silvano R. Valandro, Eric H. Hill
Summary: This study investigates the photophysical properties and aggregation behavior of asymmetric perylene and naphthalene diimides grafted to the edge of layered silicate Laponite. FRET was observed from naphthalene diimide- to perylene diimide-functionalized Laponite, with significantly enhanced FRET achieved by pillaring Laponite with a cationic surfactant. The results demonstrate the ability to tune donor-acceptor interactions and energy transfer processes in inorganic-organic hybrid materials.
JOURNAL OF PHYSICAL CHEMISTRY C
(2023)
Article
Biochemical Research Methods
Muhammad Adnan Khalid, Muhammad Mubeen, Maria Mukhtar, Zumaira Siddique, Poshmal Sumreen, Firdevs Aydin, Demet Asil, Azhar Iqbal
Summary: In this article, the synthesis of graphene quantum dots (GQDs) and surface modified CdS quantum dots (QDs) is reported. The GQDs and CdS QDs are functionalized and attached via electrostatic interactions, allowing efficient Forster resonance energy transfer (FRET). The understanding of energy transfer in the luminescent donor-acceptor FRET system has important practical implications for improving the efficiency of photovoltaics, sensing, imaging, and optoelectronic devices.
JOURNAL OF FLUORESCENCE
(2023)
Article
Chemistry, Multidisciplinary
Axel Olesund, Jessica Johnsson, Fredrik Edhborg, Shima Ghasemi, Kasper Moth-Poulsen, Bo Albinsson
Summary: This study presents a visible-to-UV triplet-triplet annihilation photon upconversion (TTA-UC) system with high quantum yield and proposes a new method to determine the annihilation rate constant. These results are of great significance for driving high-energy photochemical reactions.
JOURNAL OF THE AMERICAN CHEMICAL SOCIETY
(2022)
Article
Chemistry, Multidisciplinary
Wera Larsson, Masakazu Morimoto, Masahiro Irie, Joakim Andreasson, Bo Albinsson
Summary: Green-to-blue triplet-triplet annihilation photon upconversion is used to drive reversible photoisomerization of diarylethene (DAE) photoswitches using visible light. By carefully selecting the molecular system and experimental geometry, a single green light source can selectively trigger ring-opening and ring-closing reactions. The upconversion solution and DAE solution can be characterized concomitantly and individually without further separation processes. The efficiency of ring-closing reaction using upconverted photons is compared to direct isomerization with ultraviolet light.
CHEMISTRY-A EUROPEAN JOURNAL
(2023)
Article
Multidisciplinary Sciences
Yizhou Yang, Yanyan Chen, Fernando Izquierdo-Ruiz, Clara Schafer, Martin Rahm, Karl Borjesson
Summary: A liquid-liquid interfacial approach based on physical-organic considerations is used to synthesize an ultrathin covalent crystal film, enabling the formation of covalently bonded crystal films on a centimeter size scale with a uniform thickness of 13 nm.
NATURE COMMUNICATIONS
(2023)
Article
Chemistry, Multidisciplinary
Arpita Mukherjee, Johannes Feist, Karl Borjesson
Summary: Strong interactions between excitons and photons lead to the formation of exciton-polaritons, which possess completely different properties compared to their constituents. The rate of intersystem crossing from the polariton to the triplet states depends on the energy alignment of the excited polaritonic states. In the strong coupling regime, the rate of intersystem crossing can be substantially enhanced to the point where it approaches the rate of the radiative decay of the polariton.
JOURNAL OF THE AMERICAN CHEMICAL SOCIETY
(2023)
Review
Chemistry, Multidisciplinary
Rahul Bhuyan, Jurgen Mony, Oleg Kotov, Gabriel W. Castellanos, Jaime Gomez Rivas, Timur O. Shegai, Karl Borjesson
Summary: The interaction between molecular electronic transitions and electromagnetic fields can give rise to polaritons, which are hybrid light-matter states. The photonic contribution to these states adds complexity and allows for modifications in the photophysics and photochemistry of organic molecules. Polaritons offer opportunities for molecular photochemistry and photophysics, leading to increasing interest in the field.
Article
Chemistry, Physical
Fredrik Edhborg, Axel Olesund, Vikrant Tripathy, Yang Wang, Tumpa Sadhukhan, Andrew H. H. Olsson, Niels Bisballe, Krishnan Raghavachari, Bo W. Albinsson, Bo W. Albinsson, Amar H. H. Flood
Summary: The triplet energy of cyanostar (CS) macrocycles, which are key components of small-molecule ionic isolation lattices (SMILES), was measured using phosphorescence quenching studies. The obtained triplet energy is crucial for the design of SMILES materials for future use in triplet state engineering.
JOURNAL OF PHYSICAL CHEMISTRY A
(2023)
Article
Chemistry, Multidisciplinary
Yizhou Yang, Martin Ratsch, Austin M. Evans, Karl Borjesson
Summary: The development of covalent organic frameworks (COFs) has led to promising applications in gas storage, catalysis, drug delivery, and sensing. However, current COFs are chemically homogeneous and lack control over the spatial distribution of functionalities. This study successfully synthesized two 3D crystalline COF films that allowed for the epitaxial stacking of frameworks with similar unit cell parameters. The films showed linear growth and confirmed their high degree of polymerization and anisotropic nature.
JOURNAL OF THE AMERICAN CHEMICAL SOCIETY
(2023)
Article
Chemistry, Multidisciplinary
Axel Olesund, Shima Ghasemi, Kasper Moth-Poulsen, Bo Albinsson
Summary: This study aims to investigate the role of specific types and numbers of substituents in naphthalene annihilator compounds in visible-ultraviolet (UV) triplet-triplet annihilation photochemical upconversion (TTA-UC) processes. The research shows that the type of substituent attached to the naphthalene core is crucial for its performance as an annihilator, and larger substituents can enhance the upconverting ability.
JOURNAL OF THE AMERICAN CHEMICAL SOCIETY
(2023)
Meeting Abstract
Biophysics
Vinoth Edal Sundar Rajan, Sune Levin, Micah J. McCauley, Mark C. Williams, Ioulia F. Rouzina, Marcus Wilhelmsson, Fredrik Westerlund
BIOPHYSICAL JOURNAL
(2023)
Article
Chemistry, Multidisciplinary
Arpita Mukherjee, Johannes Feist, Karl Borjesson
Summary: Strong interactions between excitons and photons lead to the formation of exciton-polaritons. The relaxation of polaritonic states enables a new kind of energy transfer event. The rate of intersystem crossing from the polariton to the triplet states depends on the energy alignment of the excited polaritonic states. In the strong coupling regime, the rate of intersystem crossing can be substantially enhanced, which has potential applications in molecular photophysics/chemistry and organic electronics.
JOURNAL OF THE AMERICAN CHEMICAL SOCIETY
(2023)
Review
Chemistry, Multidisciplinary
Rahul Bhuyan, Jurgen Mony, Oleg Kotov, Gabriel W. Castellanos, Jaime Gomez Rivas, Timur O. Shegai, Karl Borjesson
Summary: The interaction between molecular electronic transitions and electromagnetic fields can lead to the emergence of distinct hybrid light-matter states called polaritons. Polaritons offer opportunities for modifying the photophysics and photochemistry of organic molecules beyond what is normally observed. This review focuses on the experimental landmarks in the field of polaritonic chemistry, covering the split into polariton chemistry and photochemistry, and the current status of polaritonic photochemistry and photophysics. The review also discusses the benefits, limitations, and future developments of strong exciton-photon coupling using organic molecules.
Review
Chemistry, Multidisciplinary
Andrew J. Carrod, Victor Gray, Karl Boerjesson
Summary: This article introduces two processes for increasing solar light utilization: triplet-triplet annihilation upconversion (TTA-UC) and singlet fission (SF). Although these two fields are often studied separately, they are actually reverse processes of each other. This article consolidates research in both areas, highlighting their similarities and common challenges, and provides recommendations for future work.
ENERGY & ENVIRONMENTAL SCIENCE
(2022)
Article
Computer Science, Artificial Intelligence
Yi Yu, Karl Borjesson
Summary: This study proposes a new lightweight chemical Transformer model, DeLiCaTe, by reducing the size of Transformer models in molecular science using cross-layer parameter sharing and knowledge distillation. DeLiCaTe achieves comparable performance in QSAR and VS while being more efficient in terms of parameters and layers.
MACHINE LEARNING-SCIENCE AND TECHNOLOGY
(2022)
Article
Chemistry, Physical
Pankaj Bharmoria, Fredrik Edhborg, Hakan Bildirir, Yoichi Sasaki, Shima Ghasemi, Anders Martensson, Nobuhiro Yanai, Nobuo Kimizuka, Bo Albinsson, Karl Borjesson, Kasper Moth-Poulsen
Summary: This study develops recyclable TTA-UC bioplastics by encapsulating TTA-UC chromophores liquid inside semicrystalline gelatin films, showing high-efficiency broad-spectrum upconversion. By synthesizing a new anionic annihilator and combining with a liquid surfactant and protein gelatin, the research achieves high UC quantum yield in air.
JOURNAL OF MATERIALS CHEMISTRY A
(2022)
Article
Chemistry, Multidisciplinary
Rasmus Ringstrom, Fredrik Edhborg, Zachary W. Schroeder, Lan Chen, Michael J. Ferguson, Rik R. Tykwinski, Bo Albinsson
Summary: Three pentacene dimers have been synthesized to study the effect of molecular rotation and rotational conformations on singlet fission. The results show that different conformers exhibit varying SF rates and triplet-pair recombination rates, and that viscosity affects the SF rate and triplet pair lifetime.