Role of Bcl-2 in tumour cell survival and implications for pharmacotherapy

Bim: Guardian of Tissue Homeostasis and Critical Regulator of the Immune System, Tumorigenesis and Bone Biology

(2011) Toru Akiyama et al.   ARCHIVUM IMMUNOLOGIAE ET THERAPIAE EXPERIMENTALIS

Bcl-xL Retrotranslocates Bax from the Mitochondria into the Cytosol

(2011) Frank Edlich et al.   CELL

Deciphering the rules of programmed cell death to improve therapy of cancer and other diseases

(2011) Andreas Strasser et al.   EMBO JOURNAL

Mitochondrial signaling in cell death via the Bcl-2 family

(2010) Brian Leibowitz et al.   CANCER BIOLOGY & THERAPY

FKBP38 Protects Bcl-2 from Caspase-dependent Degradation

(2010) Bo-Hwa Choi et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Apoptosis blocks Beclin 1-dependent autophagosome synthesis: an effect rescued by Bcl-xL

(2009) S Luo et al.   CELL DEATH AND DIFFERENTIATION

Mitochondria in neurodegenerative disorders: regulation of the redox state and death signaling leading to neuronal death and survival

(2009) Makoto Naoi et al.   JOURNAL OF NEURAL TRANSMISSION

WAVE1 regulates Bcl-2 localization and phosphorylation in leukemia cells

(2009) R Kang et al.   LEUKEMIA

Bim-targeted cancer therapy: A link between drug action and underlying molecular changes

(2009) T. Akiyama et al.   MOLECULAR CANCER THERAPEUTICS

BH3-only proteins in apoptosis and beyond: an overview

(2009) E Lomonosova et al.   ONCOGENE

BH3-only proteins and their roles in programmed cell death

(2009) M Giam et al.   ONCOGENE

Oncogene Addiction versus Oncogene Amnesia: Perhaps More than Just a Bad Habit?

(2008) D. W. Felsher et al.   CANCER RESEARCH

Membrane Binding by tBid Initiates an Ordered Series of Events Culminating in Membrane Permeabilization by Bax

(2008) Jonathan F. Lovell et al.   CELL

Cell death and endoplasmic reticulum stress: disease relevance and therapeutic opportunities

(2008) Inki Kim et al.   NATURE REVIEWS DRUG DISCOVERY

Promotion of PDT Efficacy by a Bcl-2 Antagonist

(2008) David Kessel   PHOTOCHEMISTRY AND PHOTOBIOLOGY

The BCL-2 protein family: opposing activities that mediate cell death

(2007) Richard J. Youle et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY