Review
Plant Sciences
Xiang Fu, Bing-Hao Shao, Xue Wei, Hui-Hui Wang, Xing Chen, Tian-tian Zhao, Chun-Mei Wang
Summary: Tubiechong, a traditional medicine widely used in China, Japan, and Singapore, has shown promising results in the treatment of various diseases, including bone disease, pain, and skin conditions. Its pharmacological activities, such as promoting blood circulation and protecting liver, heart, brain, and skin, make it a potential candidate for further development and application. However, more research is needed to explore its chemical constituents and molecular pharmacological mechanisms.
JOURNAL OF ETHNOPHARMACOLOGY
(2022)
Review
Chemistry, Medicinal
Mandisa Mangisa, Douglas Kemboi, Gerda Fouche, Rudzani Nthambeleni, Moses Kiprotich Langat, Clemence Tarirai, Martin Cheek, Odwa Gonyela, Vuyelwa Jacqueline Tembu
Summary: The compounds from Suregada Roxb. ex Rottler plants are used in traditional medicine to treat various ailments and have shown pharmacological activities such as anticancer and antioxidant properties. However, the chemical composition and medicinal uses of many species in this genus are still unknown.
Review
Plant Sciences
Patricia Matos, Maria Teresa Batista, Artur Figueirinha
Summary: Acanthus species have diverse chemical compounds and biological activities, supporting their traditional uses. Further research is needed to explore their pharmacological properties, toxicity, and action mechanisms.
JOURNAL OF ETHNOPHARMACOLOGY
(2022)
Review
Plant Sciences
Xiaofeng Chi, Faqi Zhang, Qingbo Gao, Rui Xing, Shilong Chen
Summary: Gentianaceae is a widely distributed and diverse plant family, with Gentianeae being the largest tribe. Various species from Gentianeae are used in Tibetan medicine for treating different illnesses. Phytochemical studies show that Gentianeae species contain a variety of active components with diverse biological activities.
Article
Biochemistry & Molecular Biology
Folake Idowu-Adebayo, Mary J. Toohey, Vincenzo Fogliano, Anita R. Linnemann
Summary: Adding turmeric to zobo drink can enhance the content of vitamins, polyphenols, and minerals, improving the antioxidant and nutritional quality of the drink. Consuming turmeric-fortified zobo can contribute significantly to the daily recommended intake of iron and zinc.
Review
Pharmacology & Pharmacy
Thiruventhan Karunakaran, Kok Zhuo Ngew, Ahmad Alif Danial Zailan, Vivien Yi Mian Jong, Mohamad Hafizi Abu Bakar
Summary: Mitragynine is a naturally occurring indole alkaloid extracted from the leaves of the medicinal plant Mitragyna speciosa, which shows promising analgesic effects with limited adverse effects compared to morphine. This review discusses the pharmacological and toxicological properties of mitragynine and its diastereomers, speciogynine, speciociliatine, and mitraciliatine, and explores the structure-activity relationship of these compounds.
FRONTIERS IN PHARMACOLOGY
(2022)
Review
Pharmacology & Pharmacy
Taina Santos Souza, Diogo Rodrigo Magalhaes Moreira, Henrique Rodrigues Marcelino
Summary: This review highlights the antimicrobial activity and pharmacokinetic properties of Decoquinate (DQ), and discusses the solutions currently under investigation to overcome its limitations. Pharmaceutical nanotechnology and medicinal chemistry have been used to improve the biopharmaceutical properties and pharmacokinetic profile of DQ. Based on the results presented, DQ prototypes could be tested in clinical trials for human application in the near future.
Review
Integrative & Complementary Medicine
Zeinab Vafaeipour, Bibi Marjan Razavi, Hossein Hosseinzadeh
Summary: This paper provides an updated review on the effects of turmeric and its constituent, curcumin, on metabolic syndrome (MS). Studies have shown that turmeric and curcumin have beneficial effects on different components of MS, including anti-inflammatory, anti-oxidant, antidiabetic, antihyperlipidemic, anti-obesity, and antihypertensive effects. The findings suggest that turmeric or curcumin may serve as a complementary therapy for MS. However, more clinical trials are needed to confirm these effects.
JOURNAL OF INTEGRATIVE MEDICINE-JIM
(2022)
Review
Chemistry, Multidisciplinary
Meng Tian, Yuwen Huang, Xin Wang, Maosheng Cao, Zijiao Zhao, Tong Chen, Chenfeng Yuan, Nan Wang, Boqi Zhang, Chunjin Li, Xu Zhou
Summary: Vaccaria segetalis, a dry mature seed of Vaccaria hispanica (Mill.) Rauschert, has promising clinical applications, especially in the treatment of menstrual disorders and dysmenorrhea. Studies have identified its main active ingredients and pharmacological effects, showing benefits such as prolactin-like, estrogen-like, and anti-tumor properties.
FRONTIERS IN CHEMISTRY
(2021)
Article
Chemistry, Applied
Juho Lim, Thi Thanh Hanh Nguyen, Kunal Pal, Choon Gil Kang, Chanho Park, Seung Wook Kim, Doman Kim
Summary: This study investigated the effects of solid-state fermentation of wild turmeric with Rhizopus oligosporus on phytochemical and biological properties. The results showed that fermented wild turmeric had higher concentrations of curcumin and exhibited increased antioxidant, anti-lipid accumulation, and anti-melanin formation activities. Therefore, fermented wild turmeric products can be used in the cosmeceutical and nutraceutical industries.
Review
Chemistry, Medicinal
Md Shahinozzaman, Diana N. Obanda, Shinkichi Tawata
Summary: Propolis is a resinous substance collected and processed by honeybees to seal cracks in beehives. It is categorized into seven groups based on plant source and location. Pacific, Okinawa, and Taiwanese propolis are Macaranga-type propolis with potential pharmacological benefits.
PHYTOTHERAPY RESEARCH
(2021)
Review
Plant Sciences
Hayat Ouassou, Mohamed Bouhrim, Loubna Kharchoufa, Hamada Imtara, Nour Elhouda Daoudi, Amina Benoutman, Noureddine Bencheikh, Saber Ouahhoud, Amine Elbouzidi, Mohamed Bnouham
Summary: Caralluma europaea has been traditionally used to treat various diseases such as diabetes, cancer, and kidney stones. Pharmacological reports have confirmed its antidiabetic, antioxidant, anti-inflammatory, analgesic, anti-proliferative, antibacterial, antimicrobial, and immunomodulatory effects. Further studies on phytochemistry and food preservative properties are needed for scientific exploitation of traditional uses.
JOURNAL OF ETHNOPHARMACOLOGY
(2021)
Review
Environmental Sciences
Madhuri Grover, Tapan Behl, Tarun Virmani, Saurabh Bhatia, Ahmed Al-Harrasi, Lotfi Aleya
Summary: Vetiver is a traditional plant with versatile applications, and this review compiled the latest information on its phytochemistry, pharmacology, and traditional uses. Traditional utilities of vetiver have been validated in disease-based pharmacological models, but more studies are needed to isolate active constituents and establish their mechanism of action. Additionally, the development of novel techniques for oil extraction is necessary for further exploration of its biological utilities, while attention should be paid to preventing soil erosion during cultivation and harvesting.
ENVIRONMENTAL SCIENCE AND POLLUTION RESEARCH
(2021)
Review
Biochemistry & Molecular Biology
Ashutosh Pareek, Malvika Pant, Madan Mohan Gupta, Pushpa Kashania, Yashumati Ratan, Vivek Jain, Aaushi Pareek, Anil A. A. Chuturgoon
Summary: Moringa oleifera, commonly known as the tree of life or miracle tree, is an important herbal plant with medicinal and non-medicinal benefits. This review provides an analysis of worldwide research on the plant, its pharmacological activities, phytochemical compounds, and ethnomedicinal uses. The plant has been found to contain bioactive constituents in every part, with over one hundred compounds characterized so far. Novel isolates like muramoside A&B and niazimin A&B show promising therapeutic effects. However, further research is needed to explore its traditional uses and mechanistic approach.
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
(2023)
Review
Chemistry, Medicinal
Bibi Marjan Razavi, Mahboobeh Ghasemzadeh Rahbardar, Hossein Hosseinzadeh
Summary: Turmeric and its active constituent, curcumin, possess anti-inflammatory, antinociceptive, and antioxidant effects, making them potentially effective in preventing and treating inflammatory disorders and pain. While literature and patents support their clinical application, further high-quality studies are needed to establish their clinical efficacy.
PHYTOTHERAPY RESEARCH
(2021)